Respiratory biologics are a class of targeted therapies derived from living organisms, used to treat chronic respiratory conditions. These biologics typically focus on specific molecules in the immune system, such as interleukins (IL-4, IL-5, IL-13) or immunoglobulin E (IgE), to reduce inflammation and enhance breathing. They are primarily prescribed to patients with severe, uncontrolled respiratory diseases that do not respond adequately to standard treatments such as inhaled corticosteroids and bronchodilators.
Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report's Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.
The primary conditions treated with respiratory biologics include asthma, chronic rhinosinusitis, and hypereosinophilic syndrome. Asthma is a chronic inflammatory disorder of the airways that leads to breathing problems, wheezing, and coughing due to airway narrowing and heightened sensitivity. These biologics are available in various forms, such as intravenous and subcutaneous injections, and are distributed through different channels, including hospitals, specialty clinics, retail pharmacies, and mail-order pharmacies.
The respiratory biologics market research report is one of a series of new reports from The Business Research Company that provides respiratory biologics market statistics, including the respiratory biologics industry global market size, regional shares, competitors with the respiratory biologics market share, detailed respiratory biologics market segments, market trends, and opportunities, and any further data you may need to thrive in the respiratory biologics industry. These respiratory biologics market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.
The respiratory biologics market size has grown rapidly in recent years. It will grow from $6.38 billion in 2024 to $7.47 billion in 2025 at a compound annual growth rate (CAGR) of 17.0%. The growth observed in the historical period can be attributed to several factors, including the rising prevalence of respiratory diseases, the growing adoption of personalized medicine, increased global healthcare spending, heightened awareness and diagnosis rates of respiratory conditions, and an expanding elderly population with respiratory disorders.
The respiratory biologics market size is expected to see rapid growth in the next few years. It will grow to $13.84 billion in 2029 at a compound annual growth rate (CAGR) of 16.7%. The growth projected for the forecast period can be attributed to factors such as the rising prevalence of asthma and COPD, increasing adoption of biologic therapies, higher spending on R&D, growing demand for non-invasive drug delivery methods, and the expansion of reimbursement policies. Key trends during this period include the adoption of monoclonal antibodies for respiratory diseases, advancements in biologic drug formulations and delivery techniques, regulatory approvals, strategic collaborations and acquisitions among major players, and the integration of artificial intelligence in drug discovery and development.
The growing levels of air pollution are expected to drive the expansion of the respiratory biologics market in the coming years. Air pollution refers to the presence of harmful substances, such as gases, particulate matter, and biological molecules, in the atmosphere, which can negatively impact both human health and the environment. The rise in air pollution is largely due to increased industrialization and urbanization, resulting in higher emissions from factories, vehicles, and construction activities. Respiratory biologics help address the health effects of air pollution by offering targeted therapies that reduce inflammation and enhance lung function in individuals exposed to airborne pollutants. For example, in January 2025, the United States Environmental Protection Agency (EPA) reported that over 66 million tons of pollutants were released into the atmosphere in 2023. Additionally, according to the United Nations Environment Programme in September 2022, air pollution causes 7 million premature deaths each year, and 99% of the global population breathes polluted air. Consequently, the rising levels of air pollution are driving the growth of the respiratory biologics market.
Leading companies in the respiratory biologics market are focusing on developing innovative biologic therapies, such as targeted immune treatments for chronic respiratory diseases, to provide precise treatments that reduce inflammation and enhance lung function. These targeted immune therapies for chronic respiratory diseases are designed to manage the body's immune system to reduce swelling and alleviate breathing difficulties in long-term lung conditions. For example, in September 2024, Sanofi S.A., a pharmaceutical company based in France, announced that the US Food and Drug Administration (FDA) had approved Dupixent (dupilumab) as an add-on maintenance therapy for adults with inadequately controlled chronic obstructive pulmonary disease (COPD) who have an eosinophilic phenotype. This approval was a significant milestone, making Dupixent the first biologic medication authorized in the US for this particular group of COPD patients.
In February 2024, GlaxoSmithKline plc, a UK-based pharmaceutical company, acquired Aiolos Bio for an undisclosed amount. With this acquisition, GSK aims to enhance its respiratory and immunology portfolio by gaining access to Aiolos Bio's innovative treatments for inflammatory and immune-mediated diseases. Aiolos Bio is a US-based company focused on developing biological therapies for respiratory and inflammatory conditions.
Major players in the respiratory biologics market are Pfizer Inc., Johnson & Johnson, F. Hoffmann-La Roche Ltd., Merck & Co. Inc., AbbVie Inc., Sanofi S.A., AstraZeneca plc, Novartis AG, GlaxoSmithKline plc, Amgen Inc., Viatris Inc., Regeneron Pharmaceuticals Inc., Boehringer Ingelheim International GmbH, Biogen Inc., Vertex Pharmaceuticals Incorporated, Swedish Orphan Biovitrum AB, Glenmark Pharmaceuticals Ltd., Zymeworks Inc., Kiniksa Pharmaceuticals Ltd., Pieris Pharmaceuticals Inc.
North America was the largest region in the respiratory biologics market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in respiratory biologics report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.
The countries covered in the respiratory biologics market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
The respiratory biologics market consists of sales of monoclonal antibodies (mAbs), interleukin inhibitors, and immunomodulators. Values in this market are 'factory gate' values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
Respiratory Biologics Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.
This report focuses on respiratory biologics market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
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Where is the largest and fastest growing market for respiratory biologics ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward? The respiratory biologics market global report from the Business Research Company answers all these questions and many more.
The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.
The market characteristics section of the report defines and explains the market.
The market size section gives the market size ($b) covering both the historic growth of the market, and forecasting its development.
The forecasts are made after considering the major factors currently impacting the market. These include:
The forecasts are made after considering the major factors currently impacting the market. These include the Russia-Ukraine war, rising inflation, higher interest rates, and the legacy of the COVID-19 pandemic.
Market segmentations break down the market into sub markets.
The regional and country breakdowns section gives an analysis of the market in each geography and the size of the market by geography and compares their historic and forecast growth. It covers the growth trajectory of COVID-19 for all regions, key developed countries and major emerging markets.
The competitive landscape chapter gives a description of the competitive nature of the market, market shares, and a description of the leading companies. Key financial deals which have shaped the market in recent years are identified.
The trends and strategies section analyses the shape of the market as it emerges from the crisis and suggests how companies can grow as the market recovers.
Scope
Markets Covered:1) By Disease Indication: Asthma; Chronic Rhinosinasitis; Hypereosinophilic Syndrome
2) By Route Of Administration: Intravenous; Subcuteneous
3) By Sales Channel: Hospitals; Specialty Clinics; Retail Pharmacies; Mail Order Pharmacies
Subsegments::
1) By Asthma: Severe Eosinophilic Asthma; Allergic Asthma; Non-Allergic Asthma
2) By Type: Chronic Rhinosinusitis: Chronic Rhinosinusitis with Nasal Polyps; Chronic Rhinosinusitis without Nasal Polyps
Regions: Asia-Pacific; Western Europe; Eastern Europe; North America; South America; Middle East; Africa
Time series: Five years historic and ten years forecast.
Data: Ratios of market size and growth to related markets, GDP proportions, expenditure per capita,
Data segmentations: country and regional historic and forecast data, market share of competitors, market segments.
Sourcing and Referencing: Data and analysis throughout the report is sourced using end notes.
Delivery Format: PDF, Word and Excel Data Dashboard.
Table of Contents
1. Executive Summary
2. Respiratory Biologics Market Characteristics
3. Respiratory Biologics Market Trends And Strategies
4. Respiratory Biologics Market - Macro Economic Scenario Including The Impact Of Interest Rates, Inflation, Geopolitics, Trade Wars and Tariffs, And Covid And Recovery On The Market
5. Global Respiratory Biologics Growth Analysis And Strategic Analysis Framework
5.1. Global Respiratory Biologics PESTEL Analysis (Political, Social, Technological, Environmental and Legal Factors, Drivers and Restraints)
5.2. Analysis Of End Use Industries
5.3. Global Respiratory Biologics Market Growth Rate Analysis
5.4. Global Respiratory Biologics Historic Market Size and Growth, 2019 - 2024, Value ($ Billion)
5.5. Global Respiratory Biologics Forecast Market Size and Growth, 2024 - 2029, 2034F, Value ($ Billion)
5.6. Global Respiratory Biologics Total Addressable Market (TAM)
6. Respiratory Biologics Market Segmentation
6.1. Global Respiratory Biologics Market, Segmentation By Disease Indication, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
Asthma
Chronic Rhinosinasitis
Hypereosinophilic Syndrome
6.2. Global Respiratory Biologics Market, Segmentation By Route Of Administration, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
Intravenous
Subcuteneous
6.3. Global Respiratory Biologics Market, Segmentation By Sales Channel, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
Hospitals
Specialty Clinics
Retail Pharmacies
Mail Order Pharmacies
6.4. Global Respiratory Biologics Market, Sub-Segmentation Of Asthma, By Type, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
Severe Eosinophilic Asthma
Allergic Asthma
Non-Allergic Asthma
6.5. Global Respiratory Biologics Market, Sub-Segmentation Of Chronic Rhinosinusitis, By Type, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
Chronic Rhinosinusitis with Nasal Polyps
Chronic Rhinosinusitis without Nasal Polyps
6.6. Global Respiratory Biologics Market, Sub-Segmentation Of Hypereosinophilic Syndrome (HES), By Type, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
Idiopathic HES
Lymphocytic Variant HES
Myeloproliferative HES
7. Respiratory Biologics Market Regional And Country Analysis
7.1. Global Respiratory Biologics Market, Split By Region, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
7.2. Global Respiratory Biologics Market, Split By Country, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
Region Information, Market Information, Background Information, Government Initiatives, Regulations, Regulatory Bodies, Major Associations, Taxes Levied, Corporate Tax Structure, Investments, Major Companies
8.2. Asia-Pacific Respiratory Biologics Market, Segmentation By Disease Indication, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
8.3. Asia-Pacific Respiratory Biologics Market, Segmentation By Route Of Administration, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
8.4. Asia-Pacific Respiratory Biologics Market, Segmentation By Sales Channel, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
9. China Respiratory Biologics Market
9.1. China Respiratory Biologics Market Overview
9.2. China Respiratory Biologics Market, Segmentation By Disease Indication, Historic and Forecast, 2019-2024, 2024-2029F, 2034F,$ Billion
9.3. China Respiratory Biologics Market, Segmentation By Route Of Administration, Historic and Forecast, 2019-2024, 2024-2029F, 2034F,$ Billion
9.4. China Respiratory Biologics Market, Segmentation By Sales Channel, Historic and Forecast, 2019-2024, 2024-2029F, 2034F,$ Billion
10. India Respiratory Biologics Market
10.1. India Respiratory Biologics Market, Segmentation By Disease Indication, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
10.2. India Respiratory Biologics Market, Segmentation By Route Of Administration, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
10.3. India Respiratory Biologics Market, Segmentation By Sales Channel, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
11. Japan Respiratory Biologics Market
11.1. Japan Respiratory Biologics Market Overview
11.2. Japan Respiratory Biologics Market, Segmentation By Disease Indication, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
11.3. Japan Respiratory Biologics Market, Segmentation By Route Of Administration, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
11.4. Japan Respiratory Biologics Market, Segmentation By Sales Channel, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
12. Australia Respiratory Biologics Market
12.1. Australia Respiratory Biologics Market, Segmentation By Disease Indication, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
12.2. Australia Respiratory Biologics Market, Segmentation By Route Of Administration, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
12.3. Australia Respiratory Biologics Market, Segmentation By Sales Channel, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
13. Indonesia Respiratory Biologics Market
13.1. Indonesia Respiratory Biologics Market, Segmentation By Disease Indication, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
13.2. Indonesia Respiratory Biologics Market, Segmentation By Route Of Administration, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
13.3. Indonesia Respiratory Biologics Market, Segmentation By Sales Channel, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
14. South Korea Respiratory Biologics Market
14.1. South Korea Respiratory Biologics Market Overview
14.2. South Korea Respiratory Biologics Market, Segmentation By Disease Indication, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
14.3. South Korea Respiratory Biologics Market, Segmentation By Route Of Administration, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
14.4. South Korea Respiratory Biologics Market, Segmentation By Sales Channel, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
15. Western Europe Respiratory Biologics Market
15.1. Western Europe Respiratory Biologics Market Overview
15.2. Western Europe Respiratory Biologics Market, Segmentation By Disease Indication, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
15.3. Western Europe Respiratory Biologics Market, Segmentation By Route Of Administration, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
15.4. Western Europe Respiratory Biologics Market, Segmentation By Sales Channel, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
16. UK Respiratory Biologics Market
16.1. UK Respiratory Biologics Market, Segmentation By Disease Indication, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
16.2. UK Respiratory Biologics Market, Segmentation By Route Of Administration, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
16.3. UK Respiratory Biologics Market, Segmentation By Sales Channel, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
17. Germany Respiratory Biologics Market
17.1. Germany Respiratory Biologics Market, Segmentation By Disease Indication, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
17.2. Germany Respiratory Biologics Market, Segmentation By Route Of Administration, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
17.3. Germany Respiratory Biologics Market, Segmentation By Sales Channel, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
18. France Respiratory Biologics Market
18.1. France Respiratory Biologics Market, Segmentation By Disease Indication, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
18.2. France Respiratory Biologics Market, Segmentation By Route Of Administration, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
18.3. France Respiratory Biologics Market, Segmentation By Sales Channel, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
19. Italy Respiratory Biologics Market
19.1. Italy Respiratory Biologics Market, Segmentation By Disease Indication, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
19.2. Italy Respiratory Biologics Market, Segmentation By Route Of Administration, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
19.3. Italy Respiratory Biologics Market, Segmentation By Sales Channel, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
20. Spain Respiratory Biologics Market
20.1. Spain Respiratory Biologics Market, Segmentation By Disease Indication, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
20.2. Spain Respiratory Biologics Market, Segmentation By Route Of Administration, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
20.3. Spain Respiratory Biologics Market, Segmentation By Sales Channel, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
21. Eastern Europe Respiratory Biologics Market
21.1. Eastern Europe Respiratory Biologics Market Overview
21.2. Eastern Europe Respiratory Biologics Market, Segmentation By Disease Indication, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
21.3. Eastern Europe Respiratory Biologics Market, Segmentation By Route Of Administration, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
21.4. Eastern Europe Respiratory Biologics Market, Segmentation By Sales Channel, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
22. Russia Respiratory Biologics Market
22.1. Russia Respiratory Biologics Market, Segmentation By Disease Indication, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
22.2. Russia Respiratory Biologics Market, Segmentation By Route Of Administration, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
22.3. Russia Respiratory Biologics Market, Segmentation By Sales Channel, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
23. North America Respiratory Biologics Market
23.1. North America Respiratory Biologics Market Overview
23.2. North America Respiratory Biologics Market, Segmentation By Disease Indication, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
23.3. North America Respiratory Biologics Market, Segmentation By Route Of Administration, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
23.4. North America Respiratory Biologics Market, Segmentation By Sales Channel, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
24. USA Respiratory Biologics Market
24.1. USA Respiratory Biologics Market Overview
24.2. USA Respiratory Biologics Market, Segmentation By Disease Indication, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
24.3. USA Respiratory Biologics Market, Segmentation By Route Of Administration, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
24.4. USA Respiratory Biologics Market, Segmentation By Sales Channel, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
25.2. Canada Respiratory Biologics Market, Segmentation By Disease Indication, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
25.3. Canada Respiratory Biologics Market, Segmentation By Route Of Administration, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
25.4. Canada Respiratory Biologics Market, Segmentation By Sales Channel, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
26. South America Respiratory Biologics Market
26.1. South America Respiratory Biologics Market Overview
26.2. South America Respiratory Biologics Market, Segmentation By Disease Indication, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
26.3. South America Respiratory Biologics Market, Segmentation By Route Of Administration, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
26.4. South America Respiratory Biologics Market, Segmentation By Sales Channel, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
27. Brazil Respiratory Biologics Market
27.1. Brazil Respiratory Biologics Market, Segmentation By Disease Indication, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
27.2. Brazil Respiratory Biologics Market, Segmentation By Route Of Administration, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
27.3. Brazil Respiratory Biologics Market, Segmentation By Sales Channel, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
28. Middle East Respiratory Biologics Market
28.1. Middle East Respiratory Biologics Market Overview
28.2. Middle East Respiratory Biologics Market, Segmentation By Disease Indication, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
28.3. Middle East Respiratory Biologics Market, Segmentation By Route Of Administration, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
28.4. Middle East Respiratory Biologics Market, Segmentation By Sales Channel, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
29. Africa Respiratory Biologics Market
29.1. Africa Respiratory Biologics Market Overview
29.2. Africa Respiratory Biologics Market, Segmentation By Disease Indication, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
29.3. Africa Respiratory Biologics Market, Segmentation By Route Of Administration, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
29.4. Africa Respiratory Biologics Market, Segmentation By Sales Channel, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
30. Respiratory Biologics Market Competitive Landscape And Company Profiles