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In-vitro Toxicology Testing Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, 2018-2028 Segmented By Technology, By Application, By Method, By End-User, By Region, Competition
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- Business Overview
- Company Snapshot
- Products & Services
- Financials(In case of listed companies)
- Recent Developments
- SWOT Analysis
- Charles River Laboratories International, Inc.
- SGS SA
- Merck KGaA
- Eurofins Scientific
- Abbott Laboratories
- Laboratory Corporation of America Holdings
- Evotec SE
- Thermo Fisher Scientific, Inc.
- Quest Diagnostics Incorporated
- Agilent Technolgies, Inc.
- Catalent, Inc.
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The Global In-vitro Toxicology Testing Market reached a valuation of USD 16.09 Billion in 2022 and is projected to exhibit strong growth with a Compound Annual Growth Rate (CAGR) of 9.66% and expected to reach USD 27.88 Billion by 2028. In-vitro toxicology testing involves scientific processes to assess the potential toxic effects of various substances on biological systems outside living organisms. These evaluations are typically conducted in controlled laboratory settings using test tubes, culture dishes, or artificial systems, thus replicating the Latin term "in vitro," meaning "in glass." This approach provides insights into toxicological impacts at cellular, molecular, and biochemical levels, serving as a valuable tool in assessing chemical, drug, cosmetic, and consumer product safety without subjecting animals or humans to harm.
Key Market Drivers
Increasing Demand for New Drug and Chemical Safety Assessment
Market Overview |
Forecast Period | 2024-2028 |
Market Size 2022 | USD 16.09 Billion |
Market Size 2028 | USD 27.88 Billion |
CAGR 2023-2028 | 9.66% |
Fastest Growing Segment | Cell Culture Technologies |
Largest Market | North America |
The escalating need for assessing the safety of new drugs and chemicals is a major driver for the Global In-vitro Toxicology Testing Market. Regulatory agencies such as the FDA and EMA demand comprehensive safety assessments for approval. In-vitro testing offers an efficient and cost-effective means to meet these requirements, considering ethical concerns and advancements in understanding. It aligns with reduced animal testing and accelerates safety evaluations in drug discovery.
Advancements in In-Vitro Toxicology Technologies
Technological progress in in-vitro toxicology is instrumental in market growth. Innovations in cell culture techniques, such as 3D models and organ-on-a-chip platforms, improve accuracy in mimicking tissue complexities. Automation, robotics, imaging technologies, and microfluidic devices enhance testing efficiency, predictive capabilities, and physiological relevance.
Increasing Awareness of Safety Testing Importance
Growing awareness among stakeholders about the necessity of safety assessments is a key trend driving the market. Ethical concerns, consumer awareness, regulatory guidelines, and media coverage prompt industries and researchers to prioritize safety evaluations. In-vitro testing gains prominence as a more socially responsible approach.
Key Market Challenges
Complexity of Biological Systems
Replicating intricate interactions within biological systems poses challenges. In-vitro models often fall short in reproducing systemic effects and complex physiological responses, limiting predictive accuracy.
Limited Relevance for Certain Endpoints
Some multifaceted toxicological endpoints may not be well-captured by in-vitro models. This limitation impacts the replacement of traditional animal testing and restricts application in specific regulatory and research contexts.
Long-Term and Chronic Effects
Assessing long-term and chronic effects using short-term in-vitro assays presents challenges. Complexities of chronic exposures and cumulative effects are difficult to replicate within limited time frames.
Key Market Trends
Personalized Medicine Applications
In-vitro toxicology aligns with personalized medicine trends, assessing individual responses to toxicants based on genetic and physiological characteristics. This approach aids risk assessments, informs treatment decisions, and identifies biomarkers for real-time toxicity monitoring.
Segmental Insights
Technology Insights
Reactive cell culture technology dominates the market due to its accuracy. Mimicking cellular responses in controlled environments facilitates toxicity testing across various compounds. This segment is projected to experience the highest CAGR, driven by advancements and applications.
Application Insights
Systemic toxicology testing leads the market as regulatory agencies demand comprehensive safety assessments. This approach predicts potential adverse effects on multiple organ systems without animal testing. It aids drug development and risk assessment.
Method Insights
Cellular assays are dominant due to their direct assessment of toxic effects on human cells. High-throughput capabilities and mechanistic insights into cellular pathways enhance efficiency and understanding.
End-User Insights
The pharmaceutical industry is a major end-user. Regulatory requirements, safety assessments, and early-stage risk identification drive in-vitro toxicity testing adoption in drug development.
Regional Insights
North America leads the market, supported by advanced pharmaceutical industries and stringent regulatory frameworks. Awareness of safety testing, ethical concerns, and technological advancements in the region contribute to growth.
Key Market Players
- Charles River Laboratories International, Inc.
- SGS S.A.
- Merck KGaA
- Eurofins Scientific
- Abbott Laboratories
- Laboratory Corporation of America Holdings
- Evotec S.E.
- Thermo Fisher Scientific, Inc.
- Quest Diagnostics Incorporated
- Agilent Technologies, Inc
Report Scope:
In this report, the Global In-vitro Toxicology Testing Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below.
In-vitro Toxicology Testing Market, By Technology:
- Cell Culture Technology
- High Throughput Technology
- Molecular Imaging
- OMICS Technology
In-vitro Toxicology Testing Market, By Application:
- Systemic Toxicology
- Dermal Toxicity
- Endocrine Disruption
- Occular Toxicity
- Others
In-vitro Toxicology Testing Market, By Method:
- Cellular Assay
- Biochemical Assay
- In-silico
- Ex-vivo
In-vitro Toxicology Testing Market, By End User:
- Pharmaceutical Industry
- Cosmetics & Household Products
- Academic Institutes & Research Laboratories
- Diagnostics
- Chemicals Industry
- Food Industry
Global In-vitro Toxicology Testing Market, By region:
- North America
- United States
- Canada
- Mexico
- Asia-Pacific
- China
- India
- South Korea
- Australia
- Japan
- Europe
- Germany
- France
- United Kingdom
- Spain
- Italy
- South America
- Brazil
- Argentina
- Colombia
- Middle East & Africa
- South Africa
- Saudi Arabia
- UAE
Competitive Landscape
- Company Profiles: Detailed analysis of the major companies present in the Global In-vitro Toxicology Testing Market.
Available Customizations:
- Global In-vitro Toxicology Testing Market report with the given market data, TechSci Research offers customizations according to a company's specific needs. The following customization options are available for the report:
Company Information
- Detailed analysis and profiling of additional market players (up to five).
Table of Contents
1. Product Overview
- 1.1. Market Definition
- 1.2. Scope of the Market
- 1.2.1. Markets Covered
- 1.2.2. Years Considered for Study
- 1.2.3. Key Market Segmentations
2. Research Methodology
- 2.1. Objective of the Study
- 2.2. Baseline Methodology
- 2.3. Key Industry Partners
- 2.4. Major Association and Secondary Sources
- 2.5. Forecasting Methodology
- 2.6. Data Triangulation & Validation
- 2.7. Assumptions and Limitations
3. Executive Summary
- 3.1. Overview of the Market
- 3.2. Overview of Key Market Segmentations
- 3.3. Overview of Key Market Players
- 3.4. Overview of Key Regions/Countries
- 3.5. Overview of Market Drivers, Challenges, Trends
4. Voice of Customer
5. Global In-vitro Toxicology Testing Market Outlook
- 5.1. Market Size & Forecast
- 5.2. Market Share & Forecast
- 5.2.1. By Technology (Cell Culture Technology, High Throughput Technology, Molecular Imaging, OMICS Technology)
- 5.2.2. By Application (Systemic Toxicology, Dermal Toxicity, Endocrine Disruption, Occular Toxicity, Others)
- 5.2.3. By Method (Cellular Assay, Biochemical Assay, In-Silico, Ex-Vivo)
- 5.2.4. By End-User (Pharmaceutical Industry, Cosmetics & Household Products, Academic Institutes & Research Laboratories, Diagnostics, Chemicals Industry, Food Industry)
- 5.2.5. By Company (2022)
- 5.2.6. By Region
- 5.3. Market Map
6. North America In-vitro Toxicology Testing Market Outlook
- 6.1. Market Size & Forecast
- 6.2. Market Share & Forecast
- 6.2.1. By Technology
- 6.2.2. By Application
- 6.2.3. By Method
- 6.2.4. By End-User
- 6.2.5. By Country
- 6.3. North America: Country Analysis
- 6.3.1. United States In-vitro Toxicology Testing Market Outlook
- 6.3.1.1. Market Size & Forecast
- 6.3.1.2. Market Share & Forecast
- 6.3.1.2.1. By Technology
- 6.3.1.2.2. By Application
- 6.3.1.2.3. By Method
- 6.3.1.2.4. By End-User
- 6.3.2. Mexico In-vitro Toxicology Testing Market Outlook
- 6.3.2.1. Market Size & Forecast
- 6.3.2.2. Market Share & Forecast
- 6.3.2.2.1. By Technology
- 6.3.2.2.2. By Application
- 6.3.2.2.3. By Method
- 6.3.2.2.4. By End-User
- 6.3.3. Canada In-vitro Toxicology Testing Market Outlook
- 6.3.3.1. Market Size & Forecast
- 6.3.3.2. Market Share & Forecast
- 6.3.3.2.1. By Technology
- 6.3.3.2.2. By Application
- 6.3.3.2.3. By Method
- 6.3.3.2.4. By End-User
7. Europe In-vitro Toxicology Testing Market Outlook
- 7.1. Market Size & Forecast
- 7.2. Market Share & Forecast
- 7.2.1. By Technology
- 7.2.2. By Application
- 7.2.3. By Method
- 7.2.4. By End-User
- 7.2.5. By Country
- 7.3. Europe: Country Analysis
- 7.3.1. France In-vitro Toxicology Testing Market Outlook
- 7.3.1.1. Market Size & Forecast
- 7.3.1.2. Market Share & Forecast
- 7.3.1.2.1. By Technology
- 7.3.1.2.2. By Application
- 7.3.1.2.3. By Method
- 7.3.1.2.4. By End-User
- 7.3.2. Germany In-vitro Toxicology Testing Market Outlook
- 7.3.2.1. Market Size & Forecast
- 7.3.2.2. Market Share & Forecast
- 7.3.2.2.1. By Technology
- 7.3.2.2.2. By Application
- 7.3.2.2.3. By Method
- 7.3.2.2.4. By End-User
- 7.3.3. United Kingdom In-vitro Toxicology Testing Market Outlook
- 7.3.3.1. Market Size & Forecast
- 7.3.3.2. Market Share & Forecast
- 7.3.3.2.1. By Technology
- 7.3.3.2.2. By Application
- 7.3.3.2.3. By Method
- 7.3.3.2.4. By End-User
- 7.3.4. Italy In-vitro Toxicology Testing Market Outlook
- 7.3.4.1. Market Size & Forecast
- 7.3.4.2. Market Share & Forecast
- 7.3.4.2.1. By Technology
- 7.3.4.2.2. By Application
- 7.3.4.2.3. By Method
- 7.3.4.2.4. By End-User
- 7.3.5. Spain In-vitro Toxicology Testing Market Outlook
- 7.3.5.1. Market Size & Forecast
- 7.3.5.2. Market Share & Forecast
- 7.3.5.2.1. By Technology
- 7.3.5.2.2. By Application
- 7.3.5.2.3. By Method
- 7.3.5.2.4. By End-User
8. Asia-Pacific In-vitro Toxicology Testing Market Outlook
- 8.1. Market Size & Forecast
- 8.2. Market Share & Forecast
- 8.2.1. By Technology
- 8.2.2. By Application
- 8.2.3. By Method
- 8.2.4. By End-User
- 8.2.5. By Country
- 8.3. Asia-Pacific: Country Analysis
- 8.3.1. China In-vitro Toxicology Testing Market Outlook
- 8.3.1.1. Market Size & Forecast
- 8.3.1.2. Market Share & Forecast
- 8.3.1.2.1. By Technology
- 8.3.1.2.2. By Application
- 8.3.1.2.3. By Method
- 8.3.1.2.4. By End-User
- 8.3.2. India In-vitro Toxicology Testing Market Outlook
- 8.3.2.1. Market Size & Forecast
- 8.3.2.2. Market Share & Forecast
- 8.3.2.2.1. By Technology
- 8.3.2.2.2. By Application
- 8.3.2.2.3. By Method
- 8.3.2.2.4. By End-User
- 8.3.3. South Korea In-vitro Toxicology Testing Market Outlook
- 8.3.3.1. Market Size & Forecast
- 8.3.3.2. Market Share & Forecast
- 8.3.3.2.1. By Technology
- 8.3.3.2.2. By Application
- 8.3.3.2.3. By Method
- 8.3.3.2.4. By End-User
- 8.3.4. Japan In-vitro Toxicology Testing Market Outlook
- 8.3.4.1. Market Size & Forecast
- 8.3.4.2. Market Share & Forecast
- 8.3.4.2.1. By Technology
- 8.3.4.2.2. By Application
- 8.3.4.2.3. By Method
- 8.3.4.2.4. By End-User
- 8.3.5. Australia In-vitro Toxicology Testing Market Outlook
- 8.3.5.1. Market Size & Forecast
- 8.3.5.2. Market Share & Forecast
- 8.3.5.2.1. By Technology
- 8.3.5.2.2. By Application
- 8.3.5.2.3. By Method
- 8.3.5.2.4. By End-User
9. South America In-vitro Toxicology Testing Market Outlook
- 9.1. Market Size & Forecast
- 9.2. Market Share & Forecast
- 9.2.1. By Technology
- 9.2.2. By Application
- 9.2.3. By Method
- 9.2.4. By End-User
- 9.2.5. By Country
- 9.3. South America: Country Analysis
- 9.3.1. Brazil In-vitro Toxicology Testing Market Outlook
- 9.3.1.1. Market Size & Forecast
- 9.3.1.2. Market Share & Forecast
- 9.3.1.2.1. By Technology
- 9.3.1.2.2. By Application
- 9.3.1.2.3. By Method
- 9.3.1.2.4. By End-User
- 9.3.2. Argentina In-vitro Toxicology Testing Market Outlook
- 9.3.2.1. Market Size & Forecast
- 9.3.2.2. Market Share & Forecast
- 9.3.2.2.1. By Technology
- 9.3.2.2.2. By Application
- 9.3.2.2.3. By Method
- 9.3.2.2.4. By End-User
- 9.3.3. Colombia In-vitro Toxicology Testing Market Outlook
- 9.3.3.1. Market Size & Forecast
- 9.3.3.2. Market Share & Forecast
- 9.3.3.2.1. By Technology
- 9.3.3.2.2. By Application
- 9.3.3.2.3. By Method
- 9.3.3.2.4. By End-User
10. Middle East and Africa In-vitro Toxicology Testing Market Outlook
- 10.1. Market Size & Forecast
- 10.2. Market Share & Forecast
- 10.2.1. By Technology
- 10.2.2. By Application
- 10.2.3. By Method
- 10.2.4. By End-User
- 10.2.5. By Country
- 10.3. MEA: Country Analysis
- 10.3.1. South Africa In-vitro Toxicology Testing Market Outlook
- 10.3.1.1. Market Size & Forecast
- 10.3.1.2. Market Share & Forecast
- 10.3.1.2.1. By Technology
- 10.3.1.2.2. By Application
- 10.3.1.2.3. By Method
- 10.3.1.2.4. By End-User
- 10.3.2. Saudi Arabia In-vitro Toxicology Testing Market Outlook
- 10.3.2.1. Market Size & Forecast
- 10.3.2.2. Market Share & Forecast
- 10.3.2.2.1. By Technology
- 10.3.2.2.2. By Application
- 10.3.2.2.3. By Method
- 10.3.2.2.4. By End-User
- 10.3.3. UAE In-vitro Toxicology Testing Market Outlook
- 10.3.3.1. Market Size & Forecast
- 10.3.3.2. Market Share & Forecast
- 10.3.3.2.1. By Technology
- 10.3.3.2.2. By Application
- 10.3.3.2.3. By Method
- 10.3.3.2.4. By End-User
11. Market Dynamics
- 11.1. Drivers
- 11.2. Challenges
12. Market Trends & Developments
- 12.1. Recent Developments
- 12.2. Product Launches
- 12.3. Mergers & Acquisitions
13. PESTLE Analysis
14. Porter's Five Forces Analysis
- 14.1. Competition in the Industry
- 14.2. Potential of New Entrants
- 14.3. Power of Suppliers
- 14.4. Power of Customers
- 14.5. Threat of Substitute Product
15. Competitive Landscape
- 15.1. Business Overview
- 15.2. Company Snapshot
- 15.3. Products & Services
- 15.4. Financials (In case of listed companies)
- 15.5. Recent Developments
- 15.6. SWOT Analysis
- 15.6.1. Charles River Laboratories International, Inc.
- 15.6.2. SGS S.A.
- 15.6.3. Merck KGaA
- 15.6.4. Eurofins Scientific
- 15.6.5. Abbott Laboratories
- 15.6.6. Laboratory Corporation of America Holdings
- 15.6.7. Evotec S.E.
- 15.6.8. Thermo Fisher Scientific, Inc.
- 15.6.9. Quest Diagnostics Incorporated
- 15.6.10. Agilent Technolgies, Inc.
- 15.6.11. Catalent, Inc.
16. Strategic Recommendations
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