Antibody Contract Manufacturing Market: Industry Trends and Global Forecasts, Till 2035 - Distribution by Type of Antibody Manufactured, Type of Expression System Used, Scale of Operation, and Geographical Regions
As per Roots Analysis, the global antibody contract manufacturing market is estimated to grow from USD 18.5 billion in the current year to USD 46.8 billion by 2035, at a CAGR of 9.7% during the forecast period, till 2035.
The market sizing and opportunity analysis has been segmented across the following parameters:
Type of Antibody Manufactured
Monoclonal
Bispecific
Type of Expression System Used
Mammalian
Microbial
Scale of Operation
Clinical
Commercial
Geographical Regions
North America
Europe
Asia
Latin America
Middle East and North Africa
Antibody Contract Manufacturing Market: Growth and Trends
Antibodies constitute one of the fastest growing drug classes amongst the diverse range of biologics. Over the years, there has been evolution of concepts and methods, which have facilitated several innovative advances in the development and manufacturing of increasingly complex and efficacious antibody-based therapeutics. Despite the fact that biopharmaceuticals offer significant profit margins and have been proven to be effective in treating a myriad of diseases, these therapeutic products are generally known to be associated with high costs of development and complex manufacturing protocols
In the past few years, contract manufacturers have played a critical role in the overall biopharmaceutical market. This trend has also become prevalent in the antibody manufacturing market, as developers are increasingly outsourcing their antibody manufacturing operations to contract service providers. This is a result of the diverse expertise of such third-party service providers in offering various advantages, including reduction in overall production cost. In addition, acquiring the necessary expertise and capabilities, which includes designing, constructing and maintaining a facility for manufacturing biologics in-house, requires significantly high capital investments. Therefore, many of the smaller players in the industry and, at times, certain pharma giants as well, have begun outsourcing their manufacturing operations to contract service providers.
Driven by a range of factors, including the growing demand for biologics and antibody manufacturing, technological advancements, and increasing investment in research and development, the antibody contract manufacturing market is poised to grow significantly over the coming years.
The report delves into the current state of the antibody contract manufacturing market and identifies potential growth opportunities within industry. Some key findings from the report include:
Presently, over 125 contract manufacturers claim to offer services for antibody manufacturing across the globe; 74% of the service providers manufacture monoclonal antibodies at commercial scale.
The current market landscape is fragmented, featuring the presence of both large players and new entrants; most of these are mid-sized players (43%) based in North America.
In pursuit of gaining a competitive edge in this field, stakeholders are actively upgrading their existing capabilities and adding new competencies in order to enhance their respective portfolios.
The ongoing efforts to improve capabilities and upgrade facilities have led to the establishment of industry benchmarks, which serve as a standard for new product development initiatives.
The growing interest of stakeholders in this domain is evident from the rise in partnership activity; most of the partnerships signed were focused on antibody manufacturing.
In order to enhance core competencies related to this field of research, CMOs are actively investing in upgrading existing infrastructure and expanding their respective manufacturing capacities.
The global installed antibody contract manufacturing capacity is spread across various regions; over 55% of this capacity is available in manufacturing facilities based in North America.
Given that several antibody-based drug / therapy candidates being evaluated across various stages of development, the demand for such products is anticipated to rise significantly over the next decade.
The antibody manufacturing market is likely to grow at a CAGR of 10%, till 2035; presently, majority of the market share is occupied by North America, followed by Europe.
Monoclonal Antibodies Capture the Largest Market Share
In terms of the type of antibody manufactured, the market is distributed across monoclonal and bispecific antibody. At present, the monoclonal antibody segment constitutes the majority share of the global antibody contract manufacturing market. However, players are also intensely focused on the development of bispecific antibodies for therapeutic purposes.
Microbial Expression System is the Fastest Growing Segment
In terms of the type of expression system used, the market is distributed across mammalian and microbial expression systems. Currently, the mammalian expression system segment captures the highest proportion of the global antibody contract manufacturing market given the fact that mammalian expression systems enable antibodies to achieve greater biological activity and binding affinity.
Commercial Scale Segment Occupies the Largest Share
In terms of the scale of operation, the market is distributed across clinical and commercial scale. In the current year, majority of the antibody contract manufacturing market is held by commercial scale owing to the increasing demand for commercial production of antibodies.
North America is Leading the Global Antibody Contract Manufacturing Market
In terms of key geographical regions, the market is distributed across North America, Europe, Asia, Latin America and Middle East and North Africa. North America dominates the antibody contract manufacturing market and accounts for the largest revenue share in the current year. Further, the market in Asia is likely to grow at a higher CAGR in the coming future.
Example Players in the Antibody Contract Manufacturing Market
AGC Biologics
Aldevron
Emergent BioSolutions
Eurofins CDMO
FUJIFILM Diosynth Biotechnologies
KBI Biopharma
Lonza
Nitto Avecia Pharma Services
Novasep
Pierre Fabre
Samsung BioLogics
Synthon
Thermo Fisher Scientific
Antibody Contract Manufacturing Market: Research Coverage
Market Sizing and Opportunity Analysis: The report features a thorough analysis of the global antibody contract manufacturing market, in terms of the key market segments, including [A] type of antibody manufactured, [B] type of expression system used, [C] scale of operation and [D] geographical regions.
Market Landscape: An in-depth assessment of the companies involved in antibody contract manufacturing market, based on several relevant parameters, such as [A] year of establishment, [B] company size, [C] location of headquarters, [D] location of manufacturing facilities, [E] scale of operation, [F] type of antibody, [G] type of expression systems used, [H] fill / finish operations and [I] affiliations to regulatory agencies.
Company Competitiveness Analysis: A comprehensive competitive analysis of antibody contract manufacturers, examining factors, such as [A] company strength and [B] portfolio strength and [C] portfolio diversity.
Company Profiles: Detailed profiles of key service providers engaged in the antibody contract manufacturing market, emphasizing on [A] overview of the company, [B] financial information (if available), [C] service portfolio, and [D] recent developments and an informed future outlook.
Case Study: A detailed comparison of the key features of large and small molecule drugs, along with insights into the manufacturing steps and challenges faced during these manufacturing processes.
Benchmark Analysis: A detailed benchmark analysis of the key focus areas of small, mid-sized, large and very large companies by comparing their existing capabilities within and outside their respective peer groups.
Capacity Analysis: An insightful analysis of the overall, installed capacity for manufacturing antibodies, based on various parameters, such as [A] company size and [B] key geographical regions.
Demand Analysis: An in-depth review of the annual commercial and clinical demand for antibodies, based on various relevant parameters, such as [A] target patient population, [B] dosing frequency and [C] dose strength.
SWOT Analysis: An analysis of industry-affiliated trends, opportunities and challenges, which are likely to impact the evolution of antibody contract manufacturing market.
Key Questions Answered in this Report
How many companies are currently engaged in this market?
Which are the leading companies in this market?
What factors are likely to influence the evolution of this market?
What is the current and future market size?
What is the CAGR of this market?
How is the current and future market opportunity likely to be distributed across key market segments?
Reasons to Buy this Report
The report provides a comprehensive market analysis, offering detailed revenue projections of the overall market and its specific sub-segments. This information is valuable to both established market leaders and emerging entrants.
Stakeholders can leverage the report to gain a deeper understanding of the competitive dynamics within the market. By analyzing the competitive landscape, businesses can make informed decisions to optimize their market positioning and develop effective go-to-market strategies.
The report offers stakeholders a comprehensive overview of the market, including key drivers, barriers, opportunities, and challenges. This information empowers stakeholders to stay abreast of market trends and make data-driven decisions to capitalize on growth prospects.
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TABLE OF CONTENTS
1. PREFACE
1.1. Introduction
1.2. Market Share Insights
1.3. Key Market Insights
1.4. Report Coverage
1.5. Key Questions Answered
1.6. Chapter Outlines
2. RESEARCH METHODOLOGY
2.1. Chapter Overview
2.2. Research Assumptions
2.3. Project Methodology
2.4. Forecast Methodology
2.5. Robust Quality Control
2.6. Key Market Segmentations
2.7. Key Considerations
2.7.1. Demographics
2.7.2. Economic Factors
2.7.3. Government Regulations
2.7.4. Supply Chain
2.7.5. COVID Impact
2.7.6. Market Access
2.7.7. Healthcare Policies
2.7.8. Industry Consolidation
3. ECONOMIC AND OTHER PROJECT SPECIFIC CONSIDERATIONS
3.1. Chapter Overview
3.2. Market Dynamics
3.2.1. Time Period
3.2.1.1. Historical Trends
3.2.1.2. Current and Future Estimates
3.2.2. Currency Coverage and Foreign Exchange Rate
3.2.2.1. Major Currencies Affecting the Market
3.2.2.2. Factors Affecting Currency Fluctuations and Foreign Exchange Rates
3.2.2.3. Impact of Foreign Exchange Rate Volatility on the Market
3.2.2.4. Strategies for Mitigating Foreign Exchange Risks
3.2.3. Trade Policies
3.2.3.1. Impact of Trade Barriers on the Market
3.2.3.2. Strategies for Mitigating the Risks associated with Trade Barriers
3.2.4. Recession
3.2.4.1. Historical Analysis of Past Recessions and Lessons Learnt
3.2.4.2. Assessment of Current Economic Conditions and Potential Impact on the Market
3.2.5. Inflation
3.2.5.1. Measurement and Analysis of Inflationary Pressures in the Economy
3.2.5.2. Potential Impact of Inflation on the Market Evolution
4. EXECUTIVE SUMMARY
5. INTRODUCTION
5.1. Chapter Overview
5.2. Concept of an Antibody
5.3. Structure of an Antibody
5.4. Antibody Isotypes
5.5. Mechanism of Action of Antibodies
5.6. Types of Antibodies
5.6.1. Monoclonal Antibodies
5.6.2. Bispecific Antibodies
5.6.3. Polyclonal Antibodies
5.7. Overview of Contract Manufacturing
5.8. Need for Outsourcing in the Biopharmaceutical Industry
5.9. Advantages of Outsourcing Manufacturing Services