The CGT market is evolving rapidly, with billions in investments and thousands of strategic deals shaping its trajectory. Companies that understand the landscape and anticipate future deal trends will have the competitive edge needed to thrive. Whether you are a biotech executive, investor, R&D leader, or regulatory strategist, this report provides data-driven insights to inform your next move.
TWO REPORTS FOR THE PRICE OF ONE
"Cell and Gene Therapy Market Deals: Investment, M&A, and Partnerships, 2021-2025 (3rd Edition)" is published in two installments. The first installment, released in February 2025, covers deals up to the end of 2024. The second installment will be released in Fall 2025 and will cover deals through September 2025. Customers who purchase this third edition will receive both installments. The report covers deals including financing, funding, partnering, M&A, tech transfers, IPOs/SPACs, and other deals.
"Cell and Gene Therapy Market Deals: Investment, M&A, and Partnerships, 2021-2025 (3rd Edition)" is also the companion to another 2025 Kalorama Information report, "Cell and Gene Therapy Market Dynamics by Disease Type: Development, Trends, and Forecasts 2024-2030 (4th Edition) ", which will be released in Spring 2025. The report focuses on cell and gene therapy for disease segments including oncology, neurology, musculoskeletal, dermatology, cardiology/non-oncology blood, and more. "Cell and Gene Therapy Market Dynamics by Disease Type, 4th Edition" will be available for a separate price.
The cell and gene therapy (CGT) field is at the forefront of medical innovation, fueled by cutting-edge advancements in CRISPR, next-generation sequencing (NGS), and breakthrough therapeutics. With around 2,000 companies actively engaged in the CGT industry, the sector has witnessed significant volumes of investments, strategic collaborations, and groundbreaking deals. However, shifting market dynamics-including fluctuating availability of funding of different types, evolving regulatory landscapes, and consolidation trends-have reshaped the investment outlook.
Kalorama Information's new report, "Cell and Gene Therapy Market Deals: Investment, M&A, and Partnerships, 2021-2025 (3rd Edition)", delivers an unparalleled deep dive into the CGT market's financial ecosystem, offering actionable insights into the deals that are driving the future of regenerative medicine.
Report Features
Investment & Funding Trends - Track quarterly funding fluctuations from Q1 2021 to Q4 2024, with a focus on venture capital, private equity, and public offerings.
M&A and Strategic Partnerships - Understand how acquisitions, licensing agreements, manufacturing deals, and co-marketing partnerships are shaping the competitive landscape.
Regional Market Insights - Gain a global perspective on deal activity across North America, Europe, Asia-Pacific, and emerging markets.
Top Players & Deal-Making Trends - Identify the industry's most active investors, biotech startups, and pharmaceutical leaders driving CGT growth.
Regulatory & Market Challenges - Explore how regulatory shifts, reimbursement strategies, and supply chain dynamics impact CGT deal-making.
In addition, the following is just some of the information in this report:
Quarterly Funding Amounts Q1 2021- Q4 2024 by Type and Region
Specific details of 2,000+ CGT Deals from 2021 through 2024
Venture Capital/Private Funding Round Amounts, By Quarter
Monthly VC/Private Funding, by Seed/ Angel, Series A/ B/ C/ D or PIPE/ direct offering
Chronological Trends Presented in Multiple Categories (VC, M&A, Other Areas)
Deals by Type - Technology/Research/Strategic Collaboration; Venture Capital/Private Investment; Acquisition, Merger, Strategic Investment; Licensing; Public Offering/SPAC; Manufacturing, Supply Chain; Distribution, Co-Marketing; Spinout, Restructure; Conclude/Terminate Deal; Joint Venture
Most Active Deal-Making Companies, by Type of Deal (Acquisition/Merger/ Strategic Investment, Overall Deals, Collaborations)
Regional Breakdown of Dealmaking [North America, Europe, APAC, Rest of World] (%)
Methodology
The report's insights are derived from a blend of primary and secondary research, including interviews with industry professionals, comprehensive literature reviews, and analysis of company and government reports.
Table of Contents
Chapter 1: Executive Summary
Introduction
2024 Investments
Figure 1-1: Total Deals per Month, Apr 2021-Dec 2024 (count)
Figure 1-2: Total Deals per Month, by Type, Apr 2021-Dec 2024 (count) [IPO/FPO/SPAC, VC/Private, All Other Deals]
Quarterly Funding Amounts
Table 1-1: Total Quarterly Funding and Shares, by Type, 2024 ($ million) [Collaboration Payments, IPO/FPO, M&A, SPAC, Strategic Investments, VC/Private]
Table 1-2: Total Quarterly Funding, by Type, 2023 ($ million) [Collaboration Payments, IPO/FPO, M&A, SPAC, Strategic Investments, VC/Private]
Table 1-3: Total Quarterly Funding, by Type, 2022 ($ million) [Collaboration Payments, IPO/FPO, M&A, SPAC, Strategic Investments, VC/Private]
Table 1-4: Total Quarterly Funding and Shares, by Type, 2021 ($ million) [Collaboration Payments, IPO/FPO, M&A, SPAC, Strategic Investments, VC/Private]
Figure 1-3: Total Quarterly Investment/Funding, Q1 2021-Q4 2024 ($ million)
Figure 1-4: Total Quarterly Funding, by Type, Q1 2021-Q4 2024 ($ million) [Collaboration Payments, IPO/FPO, M&A, SPAC, Strategic Investments, VC/Private]
Quarterly Funding Category Shares, Q1 2021 Through Q4 2024
Table 1-5: Total Quarterly Funding Share, by Type, 2024 (%) [Collaboration Payments, IPO/FPO, M&A, SPAC, Strategic Investments, VC/Private]
Table 1-6: Total Quarterly Funding Share, by Type, 2023 (%) [Collaboration Payments, IPO/FPO, M&A, SPAC, Strategic Investments, VC/Private]
Table 1-7: Total Quarterly Funding Share, by Type, 2022 (%) [Collaboration Payments, IPO/FPO, M&A, SPAC, Strategic Investments, VC/Private]
Table 1-8: Total Quarterly Funding Share, by Type, 2021 (%) [Collaboration Payments, IPO/FPO, M&A, SPAC, Strategic Investments, VC/Private]
Figure 1-5: Total Quarterly Funding Share, by Type, Q1 2021-Q4 2024 (%) [Collaboration Payments, IPO/FPO, M&A, SPAC, Strategic Investments, VC/Private]
Figure 1-6: 2024 Funding Share, by Type of Funding (%) [Collaboration Payments, IPO/FPO, M&A, SPAC, Strategic Investments, VC/Private]
Figure 1-7: 2023 Funding Share, by Type of Funding (%) [Collaboration Payments, IPO/FPO, M&A, SPAC, Strategic Investments, VC/Private]
Figure 1-8: 2022 Funding Share, by Type of Funding (%) [Collaboration Payments, IPO/FPO, M&A, SPAC, Strategic Investments, VC/Private]
Figure 1-9: 2021 Funding Share, by Type of Funding (%) [Collaboration Payments, IPO/FPO, M&A, SPAC, Strategic Investments, VC/Private]
Quarterly Deal Counts by Category, Q1 2021-Q4 2024
Table 1-9: Quarterly Count of Deals, By 2024 Quarter, By Category (total number) (%) [Acquisition, Merger, Strategic Investment; Conclude/Terminate Deal; Distribution, Co-Marketing; Licensing; Manufacturing, Supply Chain; Public Offering/SPAC; Spinout, Restructure, Technology/Research/Strategic Collaboration; Venture Capital/Private Investment]
Table 1-10: Quarterly Count of Deals, By 2023 Quarter, By Category (total number) (%) [Acquisition, Merger, Strategic Investment; Conclude/Terminate Deal; Distribution, Co-Marketing; Licensing; Manufacturing, Supply Chain; Public Offering/SPAC; Spinout, Restructure, Technology/Research/Strategic Collaboration; Venture Capital/Private Investment]
Table 1-11: Quarterly Count of Deals, by 2022 Quarter, By Category (total number) (%) [Acquisition, Merger, Strategic Investment; Conclude/Terminate Deal; Distribution, Co-Marketing; Licensing; Joint Venture; Manufacturing, Supply Chain; Public Offering/SPAC; Spinout, Restructure, Technology/Research/Strategic Collaboration; Venture Capital/Private Investment]
Table 1-12: Quarterly Count of Deals, by 2021 Quarter, By Category (total number) (%) [Acquisition, Merger, Strategic Investment; Conclude/Terminate Deal; Distribution, Co-Marketing; Licensing; Joint Venture; Manufacturing, Supply Chain; Public Offering/SPAC; Spinout, Restructure, Technology/Research/Strategic Collaboration; Venture Capital/Private Investment]
Table 1-13: Yearly Shares of Number of Deals, By Category, 2021-2024 (%) [Acquisition, Merger, Strategic Investment; Conclude/Terminate Deal; Distribution, Co-Marketing; Licensing; Joint Venture; Manufacturing, Supply Chain; Public Offering/SPAC; Spinout, Restructure, Technology/Research/Strategic Collaboration; Venture Capital/Private Investment]
Growth in Collaborations, Manufacturing/Supply Chain Deals, Licensing, Distribution/Co-Marketing Highlight Activity in Cell and Gene Therapy
Figure 1-10: Yearly Shares of Number of Deals, By Category, 2021-2024 (%) [Acquisition, Merger, Strategic Investment; Conclude/Terminate Deal; Distribution, Co-Marketing; Joint Venture; Licensing; Public Offering/SPAC; Manufacturing, Supply Chain; Technology/Research/Strategic Collaboration; Spinout, Restructure; Venture Capital/Private Investment]
Figure 1-11: Most Frequent Types of Deals by Quarter, by Category, 2021-2024 (Total Number) [Acquisition, Merger, Strategic Investment; Conclude/Terminate Deal; Distribution, Co-Marketing; Joint Venture; Licensing; Public Offering/SPAC; Manufacturing, Supply Chain; Technology/Research/Strategic Collaboration; Spinout, Restructure; Venture Capital/Private Investment]
A Look at Less Frequent CGT Deal Types
Figure 1-12: Lower Frequency Deal Types, by Quarter, by Category, Q1 2021-Q4 2024 (Total Number) [Conclude/Terminate Deal; Distribution, Co-Marketing; Joint Venture; Spinout, Restructure]