세계의 무세포 단백질 발현(CFPE) 시장 : 제품별, 방법별, 용도별, 최종사용자별, 지역별(2025-2033년)
Cell-free Protein Expression Market Report by Product, Method, Application, End User, and Region 2025-2033
상품코드:1701884
리서치사:IMARC
발행일:2025년 04월
페이지 정보:영문 148 Pages
라이선스 & 가격 (부가세 별도)
ㅁ Add-on 가능: 고객의 요청에 따라 일정한 범위 내에서 Customization이 가능합니다. 자세한 사항은 문의해 주시기 바랍니다.
한글목차
무세포 단백질 발현(CFPE) 시장 세계 시장 규모는 2024년 2억 8,350만 달러에 달했습니다. 향후 IMARC Group은 이 시장이 2033년까지 5억 1,510만 달러에 달하고, 2025년부터 2033년까지 6.52%의 연평균 성장률(CAGR)을 보일 것으로 예측했습니다. 이 시장은 주로 개인 맞춤형 의료, 백신 개발, 합성 생물학의 발전으로 인해 큰 성장을 이루고 있습니다. 제약 및 생명공학 분야에서 비용 효율적이고 유연한 솔루션에 대한 수요가 증가함에 따라 CFPE는 시장 성장을 더욱 촉진하고 있으며, CFPE는 중요한 산업 활성화 요인으로 자리매김하고 있습니다.
무세포 단백질 발현(CFPE)은 세포에서 추출한 생체 분자 번역 장치를 사용하여 용액에서 원하는 재조합 단백질을 생산하는 것을 말하며, 대장균, 토끼 망상 적혈구, 밀 배아, 곤충 세포, 포유류 무세포 단백질 발현(CFPE) 시스템 등 다양한 세포 용해물을 사용하여 수행 할 수 있습니다. CFPE는 효소공학, 단백질 표지, 단백질 정제, 단백질 간 상호작용, 변이체의 고처리량 생산 등에 널리 사용되고 있으며, 단백질의 안정성, 분해, 접힘에 필요한 성분 분석에도 활용되고 있습니다. 세포 기반 단백질 발현에 비해 무세포 단백질 발현(CFPE)은 시간 효율이 높고 편리하며, 비천연 아미노산을 통합할 수 있고, 안정성과 특이성을 향상시킬 수 있습니다.
무세포 단백질 발현(CFPE) 시장 동향 :
생물 과학의 급속한 발전은 시장 성장을 가속하는 중요한 요인 중 하나입니다. 무세포 단백질 발현(CFPE)은 유전 암호의 확장, 바이러스 조립, 다양한 생체 분자 공정을 위한 재조합 단백질의 합성에 널리 사용되고 있습니다. 또한, 암 및 감염 치료를 위한 항체, 항균제, 사이토카인과 같은 단백질 기반 치료제를 개발하기 위한 제약 산업에서의 기술 활용 증가는 또 다른 성장 촉진요인으로 작용하고 있습니다. 또한, 효율적인 프로토타이핑과 고처리량 실험을 위한 시스템 최적화를 통해 단백질 생산 수율을 향상시키는 머신러닝(ML) 알고리즘의 통합은 시장 성장의 원동력이 되고 있습니다. 또한, 연속 교환 무세포(CECF) 단백질 합성 시스템을 사용하여 복잡한 원핵 생물 및 진핵 생물 단백질을 생산하기 위한 새로운 공정의 도입은 시장 전망을 밝게 하고 있습니다. 다른 요인으로는 바이오 제조 및 프로토타이핑에서 무세포 방법의 광범위한 채택, 단백질체학 및 유전체학의 광범위한 조사 개발(R&D) 활동, 병원체 감지, 염증 반응 및 개인 맞춤형 의료와 같은 진단 응용 분야에서 헬스케어 산업에서 채택이 증가함에 따라 시장 성장을 가속하고 있습니다. 시장 성장을 견인하고 있습니다.
The global cell-free protein expression market size reached USD 283.5 Million in 2024. Looking forward, IMARC Group expects the market to reach USD 515.1 Million by 2033, exhibiting a growth rate (CAGR) of 6.52% during 2025-2033. The market is experiencing significant growth mainly driven by advancements in personalized medicine, vaccine development, and synthetic biology. The rising demand for cost-effective, flexible solutions in pharmaceuticals and biotechnology further propels market growth, positioning CFPE as a key industry enabler.
Cell-free protein expression (CFPE) refers to the production of desired recombinant proteins in solution using biomolecular translation machinery extracted from cells. It can be carried out using different cell lysates, such as E. coli, rabbit reticulocytes, wheat germ, insect cells, and mammalian cell-free protein expression systems. They are widely used in enzyme engineering, protein labeling, protein purification, protein-protein interaction, and high throughput production of mutants. CFPE is also used for analyzing components needed for protein stability, degradation, and folding. As compared to cell-based protein expression, cell-free protein expression is time efficient and convenient, allows the incorporation of non-natural amino acids, and provides enhanced stability and specificity.
Cell-free Protein Expression Market Trends:
The rapid advancement in biological sciences is one of the key factors driving the market growth. Cell-free protein expression is extensively used in the expansion of genetic code, assembly of viruses, and the synthesis of recombinant proteins for various biomolecular processes. Furthermore, the increasing technique utilization in the pharmaceutical industry for developing protein-based therapeutics, such as antibodies, antimicrobials, and cytokines, for treating cancer and infectious diseases is acting as another growth-inducing factor. Additionally, the integration of machine learning (ML) algorithms to improve protein production yield by optimizing the system for efficient prototyping and high-throughput experimentation is providing an impetus to market growth. Moreover, the introduction of novel processes to produce complex prokaryotic and eukaryotic proteins using a continuous-exchange cell-free (CECF) protein synthesis system is creating a positive outlook for the market. Other factors, including the widespread adoption of cell-free methods for biomanufacturing and prototyping, extensive research and development (R&D) activities in proteomics and genomics, and the rising adoption in the healthcare industry for diagnostic applications, such as pathogen sensing, inflammatory response, and personalized medicine, are supporting drive the market growth.
Key Market Segmentation:
Breakup by Product:
Expression Systems
E. coli Cell-free Protein Expression System
Wheat Germ Cell-free Protein Expression System
Rabbit Reticulocytes Cell-free Protein Expression System
Insect Cells Cell-free Protein Expression System
Human Cell-free Protein Expression System
Others
Reagents
Breakup by Method:
Transcription and Translation Systems
Translation Systems
Breakup by Application:
Enzyme Engineering
High Throughput Production
Protein Labeling
Protein-Protein Interaction
Protein Purification
Breakup by End User:
Pharmaceutical and Biotechnology Companies
Academic and Research Institutes
Others
Breakup by Region:
North America
United States
Canada
Asia-Pacific
China
Japan
India
South Korea
Australia
Indonesia
Others
Europe
Germany
France
United Kingdom
Italy
Spain
Russia
Others
Latin America
Brazil
Mexico
Others
Middle East and Africa
Competitive Landscape:
The competitive landscape of the industry has also been examined along with the profiles of the key players being Bioneer Corporation, biotechrabbit GmbH, Cambridge Isotope Laboratories Inc. (Otsuka Pharmaceutical Co. Ltd.), CellFree Sciences Co. Ltd., Cube Biotech GmbH, GeneCopoeia Inc., Jena Bioscience GmbH, Merck KGaA, New England Biolabs, Promega Corporation, Takara Bio Inc. and Thermo Fisher Scientific Inc.
Key Questions Answered in This Report
1.What was the size of the global cell-free protein expression market in 2024?
2.What is the expected growth rate of the global cell-free protein expression market during 2025-2033?
3.What are the key factors driving the global cell-free protein expression market?
4.What has been the impact of COVID-19 on the global cell-free protein expression market?
5.What is the breakup of the global cell-free protein expression market based on the product?
6.What is the breakup of the global cell-free protein expression market based on the method?
7.What is the breakup of the global cell-free protein expression market based on application?
8.What is the breakup of the global cell-free protein expression market based on the end user?
9.What are the key regions in the global cell-free protein expression market?
10.Who are the key players/companies in the global cell-free protein expression market?
Table of Contents
1 Preface
2 Scope and Methodology
2.1 Objectives of the Study
2.2 Stakeholders
2.3 Data Sources
2.3.1 Primary Sources
2.3.2 Secondary Sources
2.4 Market Estimation
2.4.1 Bottom-Up Approach
2.4.2 Top-Down Approach
2.5 Forecasting Methodology
3 Executive Summary
4 Introduction
4.1 Overview
4.2 Key Industry Trends
5 Global Cell-free Protein Expression Market
5.1 Market Overview
5.2 Market Performance
5.3 Impact of COVID-19
5.4 Market Forecast
6 Market Breakup by Product
6.1 Expression Systems
6.1.1 Market Trends
6.1.2 Key Segments
6.1.2.1 E. coli Cell-free Protein Expression System
6.1.2.2 Wheat Germ Cell-free Protein Expression System
6.1.2.3 Rabbit Reticulocytes Cell-free Protein Expression System
6.1.2.4 Insect Cells Cell-free Protein Expression System
6.1.2.5 Human Cell-free Protein Expression System
6.1.2.6 Others
6.1.3 Market Forecast
6.2 Reagents
6.2.1 Market Trends
6.2.2 Market Forecast
7 Market Breakup by Method
7.1 Transcription and Translation Systems
7.1.1 Market Trends
7.1.2 Market Forecast
7.2 Translation Systems
7.2.1 Market Trends
7.2.2 Market Forecast
8 Market Breakup by Application
8.1 Enzyme Engineering
8.1.1 Market Trends
8.1.2 Market Forecast
8.2 High Throughput Production
8.2.1 Market Trends
8.2.2 Market Forecast
8.3 Protein Labeling
8.3.1 Market Trends
8.3.2 Market Forecast
8.4 Protein-Protein Interaction
8.4.1 Market Trends
8.4.2 Market Forecast
8.5 Protein Purification
8.5.1 Market Trends
8.5.2 Market Forecast
9 Market Breakup by End User
9.1 Pharmaceutical and Biotechnology Companies
9.1.1 Market Trends
9.1.2 Market Forecast
9.2 Academic and Research Institutes
9.2.1 Market Trends
9.2.2 Market Forecast
9.3 Others
9.3.1 Market Trends
9.3.2 Market Forecast
10 Market Breakup by Region
10.1 North America
10.1.1 United States
10.1.1.1 Market Trends
10.1.1.2 Market Forecast
10.1.2 Canada
10.1.2.1 Market Trends
10.1.2.2 Market Forecast
10.2 Asia-Pacific
10.2.1 China
10.2.1.1 Market Trends
10.2.1.2 Market Forecast
10.2.2 Japan
10.2.2.1 Market Trends
10.2.2.2 Market Forecast
10.2.3 India
10.2.3.1 Market Trends
10.2.3.2 Market Forecast
10.2.4 South Korea
10.2.4.1 Market Trends
10.2.4.2 Market Forecast
10.2.5 Australia
10.2.5.1 Market Trends
10.2.5.2 Market Forecast
10.2.6 Indonesia
10.2.6.1 Market Trends
10.2.6.2 Market Forecast
10.2.7 Others
10.2.7.1 Market Trends
10.2.7.2 Market Forecast
10.3 Europe
10.3.1 Germany
10.3.1.1 Market Trends
10.3.1.2 Market Forecast
10.3.2 France
10.3.2.1 Market Trends
10.3.2.2 Market Forecast
10.3.3 United Kingdom
10.3.3.1 Market Trends
10.3.3.2 Market Forecast
10.3.4 Italy
10.3.4.1 Market Trends
10.3.4.2 Market Forecast
10.3.5 Spain
10.3.5.1 Market Trends
10.3.5.2 Market Forecast
10.3.6 Russia
10.3.6.1 Market Trends
10.3.6.2 Market Forecast
10.3.7 Others
10.3.7.1 Market Trends
10.3.7.2 Market Forecast
10.4 Latin America
10.4.1 Brazil
10.4.1.1 Market Trends
10.4.1.2 Market Forecast
10.4.2 Mexico
10.4.2.1 Market Trends
10.4.2.2 Market Forecast
10.4.3 Others
10.4.3.1 Market Trends
10.4.3.2 Market Forecast
10.5 Middle East and Africa
10.5.1 Market Trends
10.5.2 Market Breakup by Country
10.5.3 Market Forecast
11 SWOT Analysis
11.1 Overview
11.2 Strengths
11.3 Weaknesses
11.4 Opportunities
11.5 Threats
12 Value Chain Analysis
13 Porters Five Forces Analysis
13.1 Overview
13.2 Bargaining Power of Buyers
13.3 Bargaining Power of Suppliers
13.4 Degree of Competition
13.5 Threat of New Entrants
13.6 Threat of Substitutes
14 Price Analysis
15 Competitive Landscape
15.1 Market Structure
15.2 Key Players
15.3 Profiles of Key Players
15.3.1 Bioneer Corporation
15.3.1.1 Company Overview
15.3.1.2 Product Portfolio
15.3.1.3 Financials
15.3.2 biotechrabbit GmbH
15.3.2.1 Company Overview
15.3.2.2 Product Portfolio
15.3.3 Cambridge Isotope Laboratories Inc. (Otsuka Pharmaceutical Co. Ltd.)
