한글목차

약제 요약

mRNA-1345 백신은 메신저 RNA(mRNA) 백신입니다. 이 mRNA는 모두 실험실에서 만들어져 체내에서 작은 단백질 조각을 만들도록 지시하며, Moderna의 mRNA-1345 RSV 백신 후보물질은 프리퓨전 F 당단백질을 암호화하여 우수한 중화항체 반응을 유도합니다.

이 경우 백신 후보에는 RSV 당단백질 F의 mRNA 코드가 포함되어 있으며, 이 단백질은 RSV 감염을 일으키지 않지만 바이러스가 발생했을 때 신체의 면역 체계가 바이러스를 인식하고 스스로를 보호하도록 도와줍니다. 따라서 이 임상시험용 백신을 접종해도 RSV에 감염되지 않으며, mRNA-1345RSV 백신 후보물질은 젊은이와 노인(65세 이상)의 호흡기 질환의 주요 원인인 RSV로 인한 질병을 예방할 수 있습니다. mRNA-1345는 현재 노인을 대상으로 한 3상 임상시험이 진행 중이며, RSV는 소아에게도 큰 부담으로 작용하고 있으며, 소아를 대상으로 한 1상 임상시험도 진행 중입니다.

RSV 프로그램은 60세 이상 성인을 대상으로 한 호흡기세포융합바이러스(RSV) 백신 후보인 mRNA-1345에 대한 주요 임상 3상 시험의 시작을 승인했습니다. 그 결과, 이 백신이 선택된 용량에서 고령자에서 허용 가능한 안전성 프로파일을 가지고 있는 것으로 나타났습니다. 이 시험은 ConquerRSV로 알려져 있습니다.

주요 7 시장(미국·독일·프랑스·이탈리아·스페인·영국·일본)의 RSV용 mRNA-1345에 대해 조사분석했으며, 작용기서, 용법과 용량, 연구개발 활동에 관한 인사이트, 매출의 예측 등을 제공하고 있습니다.

목차

제1장 리포트의 서론

제2장 RSV에서의 mRNA-1345 개요

• 제품의 상세
• 임상 개발
  • 임상 연구
  • 임상시험 정보
  • 안전성과 유효성
• 기타 개발 활동
• 제품 개요

제3장 경쟁 구도(출시 치료법)

제4장 경쟁 구도(후기 신치료법)

제5장 mRNA-1345 시장 평가

• RSV에서 mRNA-1345의 시장 전망
• 주요 7 시장 분석
  • 주요 7 시장 RSV용 mRNA-1345의 시장 규모
• 시장 분석 : 국가별
  • 미국의 RSV용 mRNA-1345의 시장 규모
  • 독일의 RSV용 mRNA-1345의 시장 규모
  • 영국의 RSV용 mRNA-1345의 시장 규모

제6장 SWOT 분석

제7장 애널리스트의 견해

제8장 부록

제9장 DelveInsight의 서비스 내용

제10장 면책사항

제11장 DelveInsight 소개

제12장 리포트 구입 옵션

영문목차

"mRNA-1345 Market Size, Forecast, and Emerging Insight - 2032" report provides comprehensive insights about mRNA-1345 for Respiratory syncytial virus (RSV) in the seven major markets. A detailed picture of the mRNA-1345 for RSV in the 7MM, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan for the study period 2019 -2032 is provided in this report along with a detailed description of the mRNA-1345 for RSV. The report provides insights about mechanism of action, dosage and administration, as well as research and development including regulatory milestones, along with other developmental activities. Further, it also consists of future market assessments inclusive of the mRNA-1345 market forecast analysis for RSV in the 7MM, SWOT, analysts' views, comprehensive overview of market competitors, and brief about other emerging therapies in RSV.

Drug Summary:

The mRNA-1345 vaccine is a messenger RNA (mRNA) vaccine. This mRNA is entirely made in a laboratory and instructs the body to build small pieces of proteins. Moderna's mRNA-1345 RSV vaccine candidate encodes for a prefusion F glycoprotein, eliciting a superior neutralizing antibody response.

In this case, the vaccine candidate contains the mRNA code for the RSV glycoprotein F, which does not cause RSV infection but helps the body's immune system recognize and protect itself if it encounters the virus. Therefore, one cannot become infected with RSV by receiving the investigational vaccine. The mRNA-1345 RSV vaccine candidate prevents illness from RSV, a leading cause of respiratory illness in young and older adults (65+). Currently, the drug is in Phase III for older adults. mRNA-1345 is also ongoing in a Phase I trial in pediatric populations; RSV is also a large burden in the pediatric population.

RSV program has endorsed the start of the Phase III portion of the pivotal clinical study of mRNA-1345, the Company's Respiratory Syncytial Virus (RSV) vaccine candidate, in adults 60 years and older. The DSMB's endorsement comes after independent review of preliminary Phase II data, which suggest that the vaccine has an acceptable safety profile in older adults at the selected dose. This study is known as ConquerRSV.

Scope of the Report:

The report provides insights into:

• A comprehensive product overview including the mRNA-1345 description, mechanism of action, dosage and administration, research and development activities in Respiratory syncytial virus (RSV).
• Elaborated details on mRNA-1345 regulatory milestones and other development activities have been provided in this report.
• The report also highlights the mRNA-1345 research and development activities in RSV across the United States, Europe and Japan.
• The report also covers the patents information with expiry timeline around mRNA-1345.
• The report contains forecasted sales of mRNA-1345 for RSV till 2032.
• Comprehensive coverage of the late-stage emerging therapies for RSV.
• The report also features the SWOT analysis with analyst views for mRNA-1345 in RSV.

Methodology:

The report is built using data and information sourced primarily from internal databases, primary and secondary research and in-house analysis by DelveInsight's team of industry experts. Information and data from the secondary sources have been obtained from various printable and nonprintable sources like search engines, news websites, global regulatory authorities websites, trade journals, white papers, magazines, books, trade associations, industry associations, industry portals and access to available databases.

mRNA-1345 Analytical Perspective by DelveInsight

• In-depth mRNA-1345 Market Assessment

This report provides a detailed market assessment of mRNA-1345 for Respiratory syncytial virus (RSV) in the seven major markets, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan. This segment of the report provides forecasted sales data from 2024 to 2032.

• mRNA-1345 Clinical Assessment

The report provides the clinical trials information of mRNA-1345 for RSV covering trial interventions, trial conditions, trial status, start and completion dates.

Report Highlights:

• In the coming years, the market scenario for Respiratory syncytial virus (RSV) is set to change due to the extensive research and incremental healthcare spending across the world; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market.
• The companies are developing therapies that focus on novel approaches to treat/improve the disease condition, assess challenges, and seek opportunities that could influence mRNA-1345 dominance.
• Other emerging products for RSV are expected to give tough market competition to mRNA-1345 and launch of late-stage emerging therapies in the near future will significantly impact the market.
• A detailed description of regulatory milestones, and developmental activities, provide the current development scenario of mRNA-1345 in RSV.
• Our in-depth analysis of the forecasted sales data of mRNA-1345 from 2024 to 2032 will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the mRNA-1345 in RSV.

Key Questions:

• What is the product type, route of administration and mechanism of action of mRNA-1345?
• What is the clinical trial status of the study related to mRNA-1345 in Respiratory syncytial virus (RSV) and study completion date?
• What are the key collaborations, mergers and acquisitions, licensing and other activities related to the mRNA-1345 development?
• What are the key designations that have been granted to mRNA-1345 for RSV?
• What is the forecasted market scenario of mRNA-1345 for RSV?
• What are the forecasted sales of mRNA-1345 in the seven major countries, including the United States, Europe (Germany, France, Italy, Spain, and the United Kingdom), and Japan?
• What are the other emerging products available and how are these giving competition to mRNA-1345 for RSV?
• Which are the late-stage emerging therapies under development for the treatment of RSV?

Table of Contents

1. Report Introduction

2. mRNA-1345 Overview in RSV

• 2.1. Product Detail
• 2.2. Clinical Development
  • 2.2.1. Clinical studies
  • 2.2.2. Clinical trials information
  • 2.2.3. Safety and efficacy
• 2.3. Other Developmental Activities
• 2.4. Product Profile

3. Competitive Landscape (Marketed Therapies)

4. Competitive Landscape (Late-stage Emerging Therapies)

5. mRNA-1345 Market Assessment

• 5.1. Market Outlook of mRNA-1345 in RSV
• 5.2. 7MM Analysis
  • 5.2.1. Market Size of mRNA-1345 in the 7MM for RSV
• 5.3. Country-wise Market Analysis
  • 5.3.1. Market Size of mRNA-1345 in the United States for RSV
  • 5.3.2. Market Size of mRNA-1345 in Germany for RSV
  • 5.3.3. Market Size of mRNA-1345 in France for RSV
  • 5.3.4. Market Size of mRNA-1345 in Italy for RSV
  • 5.3.5. Market Size of mRNA-1345 in Spain for RSV
  • 5.3.6. Market Size of mRNA-1345 in the United Kingdom for RSV
  • 5.3.7. Market Size of mRNA-1345 in Japan for RSV

6. SWOT Analysis

7. Analysts' Views

8. Appendix

• 8.1. Bibliography
• 8.2. Report Methodology

9. DelveInsight Capabilities

10. Disclaimer

11. About DelveInsight

12. Report Purchase Options