세계의 siRNA 시장 보고서(2025년)
Small Interfering Ribonucleic Acid (RNA) Global Market Report 2025
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리서치사 : The Business Research Company
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한글목차

최근, siRNA 시장 규모는 비약적으로 확대하고 있습니다. 2024년 156억 5,000만 달러로 평가되었고, 2025년에는 188억 6,000만 달러에 달할 것으로 추정되며, CAGR 20.5%로 성장이 전망되고 있습니다. 지난 수년간의 성장은 정부 자금 증가, 유전 질환에 대한 인식 증가, siRNA 요법의 임상시험 확대, 생명 공학 기반 확대, 표적 치료제 도입 증가로 인한 것으로 예측됩니다.

siRNA 시장 규모는 향후 수년간 급격한 성장이 예상됩니다. 2029년에는 392억 6,000만 달러에 달할 것으로 예측되며, CAGR 20.1%로 성장할 전망입니다. 예측 기간의 성장은 맞춤형 의료에 대한 수요 증가, siRNA 조사에 대한 투자 확대, 제약 기업 간의 협력 강화, siRNA 기반 약물 승인 증가로 인한 것으로 예측됩니다. 예측 기간의 주요 동향으로는 전달 방법의 기술적 진보, RNAi 치료제의 혁신, 지질 나노입자 캐리어의 개발, 유전자 침묵의 연구 개발, 표적 약물 전달 시스템의 진전 등을 들 수 있습니다.

맞춤형 의료에 대한 수요 증가는 향후 수년간 siRNA 시장의 성장을 이끌 것으로 예측됩니다. 맞춤형 의료는 치료 효과를 최적화하고 치료를 개선하기 위해 환자의 유전적 요인, 환경 요인 및 생활 습관에 따라 치료법을 개별적으로 조정하는 접근법입니다. 유전체 기술의 진보로 유전적 변이를 정확하게 특정하고 개인에 맞는 치료가 가능해짐에 따라 수요가 증가하고 있습니다. siRNA은 표적 유전자 침묵을 가능하게 함으로써 맞춤형 의료를 지원하고 특정 유전성 질환 및 질병의 치료에 적합합니다. 질병을 일으키는 mRNA를 선택적으로 억제함으로써 표적 효과를 최소화하고 치료 효과와 환자 결과를 향상시킵니다. 예를 들어 미국 비영리 단체 '맞춤형 의료연합'에 따르면 2024년 2월 현재 미국 식품의약국(FDA)은 2023년 26건의 새로운 맞춤형 의료를 승인했습니다. 이것은 2022년 12건에서 현저한 증가입니다. 따라서 맞춤형 의료에 대한 수요 증가는 siRNA 시장의 성장을 이끌고 있습니다.

siRNA 치료제 시장의 주요 기업은 희소유전성 질환 치료를 위한 신규 메커니즘에 대해 규제 당국의 승인을 추구하고 있어 환자에게 지속적인 효과를 제공하고, 투여 빈도의 저감을 목표로 하고 있습니다. 규제 당국의 승인은 환자에게 치료법을 안전하게 시험, 판매 또는 사용할 수 있도록 하는 공식 인가를 의미합니다. 예를 들어, 2025년 3월에는 미국에 본사를 둔 바이오 의약품 기업인 아르니람 퍼머슈티컬즈사가 미국 식품의약국(FDA)으로부터 Qfitlia(피투실란)의 승인을 취득했습니다. 이것은 저해 인자의 유무에 관계없이 12세 이상의 성인과 청소년기 A형 또는 B형 혈우병 환자를 대상으로 한 최초의 siRNA 기반 치료법입니다. 이 요법은 항 트롬빈 농도를 낮추고 트롬빈 생성을 촉진하여 응혈을 촉진하고 출혈 에피소드를 줄이기 위해 고안되었습니다. Qfitlia는 피하 투여로 2개월에 1회의 투여 스케줄을 제공하고, 혈우병 관리에 있어서의 새로운 비인자 요법의 선택이 됩니다.

목차

제1장 주요 요약

제2장 시장 특징

제3장 시장 동향 및 전략

제4장 시장 : 금리, 인플레이션, 지정학, 무역전쟁 및 관세, 그리고 코로나 및 회복이 시장에 미치는 영향을 포함한 거시경제 시나리오

제5장 세계의 성장 분석 및 전략 분석 프레임워크

제6장 시장 세분화

제7장 지역별 및 국가별 분석

제8장 아시아태평양 시장

제9장 중국 시장

제10장 인도 시장

제11장 일본 시장

제12장 호주 시장

제13장 인도네시아 시장

제14장 한국 시장

제15장 서유럽 시장

제16장 영국 시장

제17장 독일 시장

제18장 프랑스 시장

제19장 이탈리아 시장

제20장 스페인 시장

제21장 동유럽 시장

제22장 러시아 시장

제23장 북미 시장

제24장 미국 시장

제25장 캐나다 시장

제26장 남미 시장

제27장 브라질 시장

제28장 중동 시장

제29장 아프리카 시장

제30장 경쟁 구도 및 기업 프로파일

제31장 기타 주요 기업 및 혁신 기업

제32장 세계 시장 경쟁 벤치마킹 및 대시보드

제33장 주요 인수합병(M&A)

제34장 최근 시장 동향

제35장 시장의 잠재력이 높은 국가, 부문 및 전략

제36장 부록

AJY
영문 목차

영문목차

Small interfering ribonucleic acid (RNA) is a short, double stranded RNA molecule that plays a key role in gene silencing through a process called RNA interference (RNAi). It binds to complementary messenger RNA (mRNA) sequences, causing their degradation and preventing protein synthesis. The primary purpose of siRNA is to regulate or suppress the expression of specific genes, and it is often used in research and therapeutic applications to target disease causing genes.

The main types of small interfering ribonucleic acid (RNA) include liposome systemic therapy and nanoparticle based systemic therapy. Liposome systemic therapy is a drug delivery method that uses liposomes to carry therapeutic agents throughout the body via the bloodstream. These therapies are indicated for conditions such as cardiovascular diseases, respiratory diseases, oncology, neurodegenerative diseases, and infectious diseases, serving end users such as hospitals, research institutions, pharmaceutical and biotechnology companies, and academic institutions.

Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report's Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.

The sudden escalation of U.S. tariffs and the consequent trade frictions in spring 2025 are severely impacting the pharmaceutical companies contend with tariffs on APIs, glass vials, and lab equipment inputs with few alternative sources. Generic drug makers, operating on razor-thin margins, are especially vulnerable, with some reducing production of low-profit medicines. Biotech firms face delays in clinical trials due to tariff-related shortages of specialized reagents. In response, the industry is expanding API production in India and Europe, increasing inventory stockpiles, and pushing for trade exemptions for essential medicines.

The small interfering ribonucleic acid (RNA) market research report is one of a series of new reports from the business research company that provides small interfering ribonucleic acid (RNA) market statistics, including small interfering ribonucleic acid (RNA) industry global market size, regional shares, competitors with a small interfering ribonucleic acid (RNA) market share, detailed small interfering ribonucleic acid (RNA) market segments, market trends and opportunities, and any further data you may need to thrive in the small interfering ribonucleic acid (RNA) industry. This small interfering ribonucleic acid (RNA) market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The small interfering ribonucleic acid (RNA) market size has grown exponentially in recent years. It will grow from $15.65 billion in 2024 to $18.86 billion in 2025 at a compound annual growth rate (CAGR) of 20.5%. The growth in the historic period can be attributed to rising government funding, increasing awareness of genetic disorders, growing clinical trials for small interfering ribonucleic acid (siRNA) therapies, expansion of biotechnology infrastructure, and rising adoption of targeted therapeutics. biotechnology infrastructure, and increasing adoption of targeted therapeutics.

The small interfering ribonucleic acid (RNA) market size is expected to see exponential growth in the next few years. It will grow to $39.26 billion in 2029 at a compound annual growth rate (CAGR) of 20.1%. The growth in the forecast period can be attributed to rising demand for personalized medicine, growing investment in small interfering ribonucleic acid (siRNA) research, increasing collaborations between pharma companies, and rising approvals of small interfering ribonucleic acid (siRNA) based drugs. Major trends in the forecast period include technological advancements in delivery methods, innovations in RNAi therapeutics, developments in lipid nanoparticle carriers, research and development in gene silencing, and advancements in targeted drug delivery systems.

The rising demand for personalized medicine is expected to drive the growth of the small interfering ribonucleic acid (RNA) market in the coming years. Personalized medicine is an approach that tailors treatments to individual patients based on their genetic, environmental, and lifestyle factors to optimize outcomes and improve care. Demand is increasing due to advancements in genomic technologies, which allow precise identification of genetic variations and enable customized treatments for individuals. Small interfering ribonucleic acid (siRNA) supports personalized medicine by enabling targeted gene silencing, making it suitable for treating specific genetic disorders and diseases. It minimizes off-target effects by selectively inhibiting disease-causing mRNA, enhancing therapeutic efficacy and patient outcomes. For example, in February 2024, according to the Personalized Medicine Coalition, a US based nonprofit organization, the U.S. Food and Drug Administration approved 26 new personalized medicines in 2023, a notable increase from 12 approvals in 2022. Therefore, the growing demand for personalized medicine is driving the expansion of the small interfering ribonucleic acid (RNA) market.

Major companies in the small interfering ribonucleic acid (siRNA) therapeutics market are pursuing regulatory approvals for novel mechanisms to treat rare genetic diseases, aiming to provide sustained effects and reduce dosing frequency for patients. Regulatory approvals are official clearances that permit a therapy to be safely tested, marketed, or used in patients. For instance, in March 2025, Alnylam Pharmaceuticals Inc., a US based biopharmaceutical company, received approval from the U.S. Food and Drug Administration for Qfitlia (fitusiran), the first siRNA-based therapy for adults and adolescents aged 12 years and older with hemophilia A or B, with or without inhibitors. The therapy is designed to lower antithrombin levels, enhancing thrombin generation to promote clot formation and reduce bleeding episodes. Qfitlia provides a subcutaneous, once-every-two-month dosing regimen, offering a novel, non-factor therapeutic option for hemophilia management.

In May 2025, AbbVie Inc., a US based biopharmaceutical company, partnered with ADARx Pharmaceuticals Inc. Through this partnership, AbbVie aims to combine ADARx's proprietary RNA technology with its scientific expertise to develop next-generation siRNA therapies, advancing treatment in neuroscience, immunology, and oncology. ADARx Pharmaceuticals Inc. is a biotechnology company developing siRNA-based therapies that target specific mRNA to treat diseases.

Major companies operating in the small interfering ribonucleic acid (rna) market are Novartis AG, Thermo Fisher Scientific Inc., GlaxoSmithKline plc, Sanofi S.A., Sarepta Therapeutics Inc., Alnylam Pharmaceuticals Inc., Ionis Pharmaceuticals Inc., Wave Life Sciences Ltd., Silence Therapeutics plc, Arrowhead Pharmaceuticals Inc., Quark Pharmaceuticals Inc., Arbutus Biopharma Corporation, Evox Therapeutics Ltd., Phio Pharmaceuticals Inc., Genecon Biotechnologies Co., Ltd., Olix Pharmaceuticals, Inc., Benitec Biopharma Ltd., Bio-Path Holdings, Inc., Calando Pharmaceuticals, Inc., Sirnaomics, Ltd.

North America was the largest region in the small interfering ribonucleic acid (RNA) market in 2024. The regions covered in small interfering ribonucleic acid (RNA) report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

The countries covered in the small interfering ribonucleic acid (RNA) market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

The small interfering ribonucleic acid (RNA) market consists of revenues earned by entities by providing services such as gene silencing assays, delivery system development, molecular diagnostics, preclinical testing, and laboratory research support. The market value includes the value of related goods sold by the service provider or included within the service offering. The small interfering ribonucleic acid (RNA) market also includes sales of synthesis kits, lipid nanoparticles, delivery vectors, RNAi assay kits, transfection reagents, and RNA extraction kits. Values in this market are 'factory gate' values, that is, the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

Small Interfering Ribonucleic Acid (RNA) Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.

This report focuses on small interfering ribonucleic acid (rna) market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.

Reasons to Purchase

Where is the largest and fastest growing market for small interfering ribonucleic acid (rna) ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The small interfering ribonucleic acid (rna) market global report from the Business Research Company answers all these questions and many more.

The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.

The forecasts are made after considering the major factors currently impacting the market. These include the technological advancements such as AI and automation, Russia-Ukraine war, trade tariffs (government-imposed import/export duties), elevated inflation and interest rates.

Scope

Table of Contents

1. Executive Summary

2. Small Interfering Ribonucleic Acid (RNA) Market Characteristics

3. Small Interfering Ribonucleic Acid (RNA) Market Trends And Strategies

4. Small Interfering Ribonucleic Acid (RNA) Market - Macro Economic Scenario Including The Impact Of Interest Rates, Inflation, Geopolitics, Trade Wars and Tariffs, And Covid And Recovery On The Market

5. Global Small Interfering Ribonucleic Acid (RNA) Growth Analysis And Strategic Analysis Framework

6. Small Interfering Ribonucleic Acid (RNA) Market Segmentation

7. Small Interfering Ribonucleic Acid (RNA) Market Regional And Country Analysis

8. Asia-Pacific Small Interfering Ribonucleic Acid (RNA) Market

9. China Small Interfering Ribonucleic Acid (RNA) Market

10. India Small Interfering Ribonucleic Acid (RNA) Market

11. Japan Small Interfering Ribonucleic Acid (RNA) Market

12. Australia Small Interfering Ribonucleic Acid (RNA) Market

13. Indonesia Small Interfering Ribonucleic Acid (RNA) Market

14. South Korea Small Interfering Ribonucleic Acid (RNA) Market

15. Western Europe Small Interfering Ribonucleic Acid (RNA) Market

16. UK Small Interfering Ribonucleic Acid (RNA) Market

17. Germany Small Interfering Ribonucleic Acid (RNA) Market

18. France Small Interfering Ribonucleic Acid (RNA) Market

19. Italy Small Interfering Ribonucleic Acid (RNA) Market

20. Spain Small Interfering Ribonucleic Acid (RNA) Market

21. Eastern Europe Small Interfering Ribonucleic Acid (RNA) Market

22. Russia Small Interfering Ribonucleic Acid (RNA) Market

23. North America Small Interfering Ribonucleic Acid (RNA) Market

24. USA Small Interfering Ribonucleic Acid (RNA) Market

25. Canada Small Interfering Ribonucleic Acid (RNA) Market

26. South America Small Interfering Ribonucleic Acid (RNA) Market

27. Brazil Small Interfering Ribonucleic Acid (RNA) Market

28. Middle East Small Interfering Ribonucleic Acid (RNA) Market

29. Africa Small Interfering Ribonucleic Acid (RNA) Market

30. Small Interfering Ribonucleic Acid (RNA) Market Competitive Landscape And Company Profiles

31. Small Interfering Ribonucleic Acid (RNA) Market Other Major And Innovative Companies

32. Global Small Interfering Ribonucleic Acid (RNA) Market Competitive Benchmarking And Dashboard

33. Key Mergers And Acquisitions In The Small Interfering Ribonucleic Acid (RNA) Market

34. Recent Developments In The Small Interfering Ribonucleic Acid (RNA) Market

35. Small Interfering Ribonucleic Acid (RNA) Market High Potential Countries, Segments and Strategies

36. Appendix

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