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In-Vitro Toxicology Testing Global Market Report 2025
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In-vitro toxicology testing encompasses a range of assays and tests utilized to determine toxic dosages of substances like drugs, nutraceuticals, and food additives, identifying their potential toxicity upon administration. Its primary goal is to detect the presence of harmful chemicals and residual solvents, effectively reducing exposure to hazardous elements. This form of testing is predominantly employed in assessing medication doses that demonstrate toxicity during preclinical development, drug discovery, and development stages.

The core products within in-vitro toxicology testing comprise consumables, assays, equipment, software, and services. Consumables encompass various products utilized in laboratory testing procedures, including items like cannulas and lancets for compound analysis. The methods employed consist of cellular assays, biochemical assays, in silico models, and ex vivo models, employing technologies such as cell culture and high-throughput methodologies. These techniques are applied across various applications, encompassing neurotoxicity, dermal toxicity, cytotoxicity, and other related domains. The industry verticals served include pharmaceuticals, biopharmaceuticals, cosmetics, household products, food, and chemicals.

Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report's Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.

The sharp rise in U.S. tariffs and the resulting trade tensions in spring 2025 are having a significant impact on the healthcare sector, especially in the supply of essential medical devices, diagnostic equipment, and pharmaceuticals. Hospitals and healthcare providers are grappling with higher costs for imported surgical tools, imaging systems, and consumables like syringes and catheters, many of which have limited domestic substitutes. These escalating expenses are putting pressure on healthcare budgets, prompting some providers to delay equipment upgrades or pass increased costs on to patients. Furthermore, tariffs on raw materials and components are disrupting the manufacturing of vital drugs and devices, leading to supply chain delays. In response, the industry is adopting diversified sourcing strategies, expanding local production where feasible, and pushing for tariff exemptions on critical medical products.

The in-vitro toxicology testing market research report is one of a series of new reports from The Business Research Company that provides in-vitro toxicology testing market statistics, including in-vitro toxicology testing industry global market size, regional shares, competitors with an in-vitro toxicology testing market share, detailed in-vitro toxicology testing market segments, market trends and opportunities, and any further data you may need to thrive in the in-vitro toxicology testing industry. This in-vitro toxicology testing market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The in-vitro toxicology testing market size has grown rapidly in recent years. It will grow from $11.53 billion in 2024 to $12.73 billion in 2025 at a compound annual growth rate (CAGR) of 10.4%. The growth in the historic period can be attributed to regulatory requirements, ethical concerns and animal welfare, cost and time efficiency, globalization of the pharmaceutical industry, drug discovery and development demands, public awareness of environmental toxins.

The in-vitro toxicology testing market size is expected to see rapid growth in the next few years. It will grow to $19.02 billion in 2029 at a compound annual growth rate (CAGR) of 10.6%. The growth in the forecast period can be attributed to focus on personalized medicine, demand for predictive toxicology models, expansion of environmental testing, oncology drug development challenges, focus on endocrine disruptor screening, shift towards multi-organ chips. Major trends in the forecast period include advancements in 3d cell culture technologies, integration of high-throughput screening, focus on organ-on-a-chip technologies, application in chemical safety assessment, use of human-derived cell lines, incorporation of omics technologies, educational initiatives and training programs.

The forecast of 10.6% growth over the next five years reflects a slight reduction of 0.1% from the previous projection. This reduction is primarily due to the impact of tariffs between the US and other countries. Trade tensions could hinder drug safety monitoring by inflating prices of mass spectrometry reagents and hepatotoxicity assay kits developed in Germany and Singapore, resulting in slower pharmaceutical testing and higher lab screening costs. The effect will also be felt more widely due to reciprocal tariffs and the negative effect on the global economy and trade due to increased trade tensions and restrictions.

The increasing healthcare expenditure is anticipated to drive growth in the in-vitro toxicology testing market. Healthcare expenditure refers to the total amount of money spent by individuals and the government on services such as hospitals, home health services, prescription medications, nursing facilities, and personal healthcare. This spending is rising globally due to the increasing prevalence of diseases that necessitate in-vitro toxicology testing. For example, a report published by the Centers for Medicare & Medicaid Services, a U.S. federal agency, projects that from 2023 to 2032, the average growth rate of national health expenditure (NHE) will be 5.6%, exceeding the average GDP growth rate of 4.3%. Consequently, the proportion of health spending relative to GDP is expected to rise from 17.3% in 2022 to 19.7% by 2032. Therefore, the rising healthcare expenditure is driving the growth of the in-vitro toxicology testing market.

The in-vitro toxicology testing market is set to experience a boost owing to the expanding pharmaceutical industry. This sector, responsible for researching, developing, producing, and marketing pharmaceutical drugs, is witnessing an increased demand for in-vitro toxicology testing services. These services play a critical role in screening new drug candidates and ensuring the safety of existing products. A March 2022 report by Atradius revealed that the US pharmaceutical market represents roughly 45% of the global market and contributes to 22% of the world's production, signifying significant growth potential in driving the demand for in-vitro toxicology testing within this industry.

The rise of innovative cell therapies is a prominent trend gaining momentum in the in-vitro toxicology market. Key players in the in-vitro toxicology testing industry are focusing on developing new funding solutions to strengthen their competitive edge. For instance, in June 2024, Waypoint Bio, a biotechnology company based in the U.S., announced that it had secured $14.5 million in seed funding for its novel cell therapies aimed at solid tumors, employing in vivo spatial pooled screening technology. This platform uniquely integrates spatial biology with pooled screening, allowing for the simultaneous examination of how various cell therapy candidates interact with the solid tumor microenvironment. The system evaluates hundreds of phenotypes at the single-cell level, providing researchers with valuable insights into not only which therapies prove effective but also the reasons behind their successes or failures based on interactions within the tumor environment.

Leading companies in the in-vitro toxicology testing market are pursuing strategic partnerships to enhance their capabilities in providing inhalation toxicology tests and strengthen their market positions. Strategic partnerships involve companies leveraging each other's strengths and resources for mutual benefit and success. For example, in November 2024, Charles River Laboratories International Inc., a U.S.-based provider of pharmaceutical products and services, partnered with Met Tak Life Sciences, a U.S.-based biotechnology firm, to develop a novel approach methodology (NAM) inhalation toxicology test aimed at reducing dependence on traditional animal research methods. By integrating MatTek's advanced 3D human tissue models into their toxicology testing workflows, the collaboration seeks to bridge the gap between animal testing and human biology.

In January 2022, Inotiv Inc., a U.S.-based contract research organization, acquired Integrated Laboratory Systems, LLC for $56 million. This acquisition is set to enhance Inotiv's expertise in computational and in vitro methods for predictive toxicology assessments. Integrated Laboratory Systems, LLC, also based in the U.S., specializes in providing in vivo and in vitro toxicology services.

Major companies operating in the in-vitro toxicology testing market are Thermo Fisher Scientific Inc., Merck KGaA, Laboratory Corporation of America Holdings (LabCorp), Gentronix Limited (a subsidiary of Eurofins Scientific SE), Bio-Rad Laboratories Inc., Eurofins Scientific SE, Charles River Laboratories International Inc., Promega Corporation, Agilent Technologies Inc., Evotec SE, SGS SA, BioIVT LLC, MB Research Laboratories LLC, Creative Biolabs Inc., Creative Bioarray Inc., InSphero AG, PerkinElmer Inc., Cyprotex PLC, MatTek Corporation, Danaher Corporation, Ncardia AG, Sekisui Chemical Co. Ltd., BioReliance Corporation, CellSystems Biotechnologie Vertrieb GmbH, Taconic Biosciences Inc., Biopredic International, MultiCell Technologies Inc., Altasciences Clinical Research Holdings Inc., Molecular Toxicology Inc., Toxys BV, XenoTech LLC, Optivia Biotechnology Inc., Toxikon Corporation

North America was the largest region in the in- vitro toxicology testing market in 2024. Asia-Pacific is expected to be the fastest-growing region in the in- vitro toxicology testing market report during the forecast period. The regions covered in the in-vitro toxicology testing market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

The countries covered in the in-vitro toxicology testing market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

The in-vitro toxicology testing market includes revenues earned by entities by providing metabolic, toxicokinetic, and bioanalytical investigations. The market value includes the value of related goods sold by the service provider or included within the service offering. Only goods and services traded between entities or sold to end consumers are included.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

In-Vitro Toxicology Testing Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.

This report focuses on in-vitro toxicology testing market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.

Reasons to Purchase

Where is the largest and fastest growing market for in-vitro toxicology testing ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The in-vitro toxicology testing market global report from the Business Research Company answers all these questions and many more.

The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.

The forecasts are made after considering the major factors currently impacting the market. These include the technological advancements such as AI and automation, Russia-Ukraine war, trade tariffs (government-imposed import/export duties), elevated inflation and interest rates.

Scope

Table of Contents

1. Executive Summary

2. In-Vitro Toxicology Testing Market Characteristics

3. In-Vitro Toxicology Testing Market Trends And Strategies

4. In-Vitro Toxicology Testing Market - Macro Economic Scenario Including The Impact Of Interest Rates, Inflation, Geopolitics, Trade Wars and Tariffs, And Covid And Recovery On The Market

5. Global In-Vitro Toxicology Testing Growth Analysis And Strategic Analysis Framework

6. In-Vitro Toxicology Testing Market Segmentation

7. In-Vitro Toxicology Testing Market Regional And Country Analysis

8. Asia-Pacific In-Vitro Toxicology Testing Market

9. China In-Vitro Toxicology Testing Market

10. India In-Vitro Toxicology Testing Market

11. Japan In-Vitro Toxicology Testing Market

12. Australia In-Vitro Toxicology Testing Market

13. Indonesia In-Vitro Toxicology Testing Market

14. South Korea In-Vitro Toxicology Testing Market

15. Western Europe In-Vitro Toxicology Testing Market

16. UK In-Vitro Toxicology Testing Market

17. Germany In-Vitro Toxicology Testing Market

18. France In-Vitro Toxicology Testing Market

19. Italy In-Vitro Toxicology Testing Market

20. Spain In-Vitro Toxicology Testing Market

21. Eastern Europe In-Vitro Toxicology Testing Market

22. Russia In-Vitro Toxicology Testing Market

23. North America In-Vitro Toxicology Testing Market

24. USA In-Vitro Toxicology Testing Market

25. Canada In-Vitro Toxicology Testing Market

26. South America In-Vitro Toxicology Testing Market

27. Brazil In-Vitro Toxicology Testing Market

28. Middle East In-Vitro Toxicology Testing Market

29. Africa In-Vitro Toxicology Testing Market

30. In-Vitro Toxicology Testing Market Competitive Landscape And Company Profiles

31. In-Vitro Toxicology Testing Market Other Major And Innovative Companies

32. Global In-Vitro Toxicology Testing Market Competitive Benchmarking And Dashboard

33. Key Mergers And Acquisitions In The In-Vitro Toxicology Testing Market

34. Recent Developments In The In-Vitro Toxicology Testing Market

35. In-Vitro Toxicology Testing Market High Potential Countries, Segments and Strategies

36. Appendix

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