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ADC Technology Market by Generation of Technology, Type of Conjugation, Type of Linker, Type of Payment Model Adopted and Key Geographical Regions : Industry Trends and Global Forecasts, Till 2035
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ADC TECHNOLOGY MARKET (FOCUS ON ADC LINKER & ADC CONJUGATION TECHNOLOGIES): OVERVIEW

As per Roots Analysis, the global ADC technology market is estimated to grow from USD 1.18 billion in the current year to USD 4.37 billion by 2035, at a CAGR of 11.5% during the forecast period, till 2035.

The market sizing and opportunity analysis has been segmented across the following parameters:

Generation of Technology

Type of Conjugation

Type of Linker

Type of Payment Model Adopted

Key Geographical Regions

ADC TECHNOLOGY MARKET (FOCUS ON ADC LINKER & ADC CONJUGATION TECHNOLOGIES): GROWTH AND TRENDS

Antibody drug conjugate has emerged as a versatile anti-cancer therapy that has been proven to be more effective and less toxic to patients. Such interventions are designed to identify specific antigens that are expressed on the surface of cancer (target) cells so that the effects of the cytotoxin / drug are focused on the elimination of only the cancerous cells. Over the past few years, more than 20 ADC therapies have been approved by various regulatory agencies. Moreover, over 350 drug therapies are being evaluated in clinical trials across the globe. This demonstrates the extensive development initiatives that are being undertaken by stakeholders in this domain. However, the complex design and structure of ADCs present a significant challenge to the overall tolerability and efficacy of the molecule. Thus, more advanced ADC technology is required to generate the controlled assembly of ADCs while maintaining tolerability and safety profiles. It is worth highlighting that significant investments have been made in the ADC technology market in order to meet the growing demand for antibody drug conjugates. As drug developers invest more in these innovative therapies, the market for ADC technology is likely to witness substantial market growth during the forecast period.

ADC TECHNOLOGY MARKET (FOCUS ON ADC LINKER & ADC CONJUGATION TECHNOLOGIES): KEY INSIGHTS

The report delves into the current state of the ADC technology market and identifies potential growth opportunities within the industry. Some key findings from the report include:

1. At present, over 95 ADC linker and conjugation technologies are being offered by various technology developers across the globe; around 55% of these are third-generation technologies.

2. The current market landscape is highly fragmented, featuring the presence of both new entrants and well-established players across key geographical regions.

3. Over 2,100 patents have been filed / granted for ADC linker and conjugation technologies, by industry and non-industry players, to protect the intellectual property generated within this field.

4. To cater to the increasing demand for homogenous ADC therapies, a number of players have stepped up to introduce technologically advanced platforms and establish a strong brand position in this industry.

5. A considerable increase in partnership activity has been witnessed in this domain; ~70% of the deals were related to licensing of technologies, primarily focused on product development and R&D purposes.

6. ADC drug developers are anticipated to continue to form strategic alliances with ADC linker and conjugation technology providers to further strengthen their respective technology portfolios.

7. Stakeholders have adopted different business models to maximize the gain from ADC technologies; a considerable number of players have signed multiple partnerships to out-license their technologies.

8. In pursuit of gaining a competitive edge, stakeholders are actively enhancing their existing capabilities to improve their respective technology portfolios and compliance with evolving industry standards.

9. At present, over 350 ADC therapeutic candidates are undergoing clinical trials for the treatment of various oncological disorders; majority of these ADCs are being evaluated as monotherapies.

10. With the growing focus on development of efficacious and site-selective drugs, the ADCs linker and conjugation technologies market is anticipated to witness an annualized growth of ~15%, over the next decade.

11. The estimated market opportunity is projected to be well distributed across different types of linkers and key geographical regions.

ADC TECHNOLOGY MARKET (FOCUS ON ADC LINKER & ADC CONJUGATION TECHNOLOGIES): KEY SEGMENTS

Third-Generation Technologies are Likely to Dominate the ADC Technology Market During the Forecast Period

Based on the generation of technology, the market is segmented into second-generation, third-generation and next-generation. It is worth highlighting that majority of the current ADC technology market is captured by third-generation technologies and this trend is likely to remain the same in the forthcoming years.

Currently, Chemical Conjugation Segment Occupies the Largest Share of the ADC Technology Market

Based on the type of conjugation, the market is segmented into chemical, chemoenzymatic and enzymatic. The current market is expected to be driven by chemical conjugators. It is worth highlighting that the chemoenzymatic segment is likely to grow at a relatively higher CAGR, during the forecast period.

Cleavable Segment is Likely to Capture the Largest Share of the ADC Technology Market During the Forecast Period

Based on the type of linker, the market is segmented into cleavable and non-cleavable. It is worth highlighting that majority of the current ADC technology market is captured by cleavable linkers and this trend is unlikely to change in the mid-long term.

North America Accounts for the Largest Share of the Market

Based on key geographical regions, the market is segmented into North America, Europe, and Asia-Pacific and Rest of the World. A significant proportion of the market is expected to be captured by North America and Europe. It is worth highlighting that, over the years, the market in Asia-Pacific and Rest of the World is expected to grow at a higher CAGR.

Example Players in the ADC Technology Market

Primary Research Overview

The opinions and insights presented in this study were influenced by discussions conducted with multiple stakeholders. The research report features detailed transcripts of interviews held with the following industry stakeholders:

ADC TECHNOLOGY MARKET (FOCUS ON ADC LINKER & ADC CONJUGATION TECHNOLOGIES): RESEARCH COVERAGE

KEY QUESTIONS ANSWERED IN THIS REPORT

REASONS TO BUY THIS REPORT

ADDITIONAL BENEFITS

TABLE OF CONTENTS

1. PREFACE

2. EXECUTIVE SUMMARY

3. INTRODUCTION

4. ADC LINKER AND CONJUGATION TECHNOLOGIES: MARKET LANDSCAPE

5 TECHNOLOGY COMPETITIVENESS ANALYSIS

6. COMPANY PROFILES

7. PATENT ANALYSIS

8. PARTNERSHIPS AND COLLABORATIONS

9. BUSINESS MODEL ANALYSIS

10. LIKELY PARTNERS ANALYSIS

11. BRAND POSITIONING ANALYSIS

12. CASE STUDY: ANTIBODY DRUG CONJUGATES

13. MARKET SIZING AND OPPORTUNITY ANALYSIS

14. EXECUTIVE INSIGHTS

15. CONCLUDING REMARKS

16. APPENDIX 1: TABULATED DATA

17. APPENDIX 2: LIST OF COMPANIES AND ORGANIZATIONS

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