Calcineurin Inhibitor Market is estimated to be valued at USD 12.37 Bn in 2025 and is expected to reach USD 25.36 Bn by 2032, growing at a compound annual growth rate (CAGR) of 10.8% from 2025 to 2032.
Report Coverage
Report Details
Base Year:
2024
Market Size in 2025:
USD 12.37 Bn
Historical Data for:
2020 To 2024
Forecast Period:
2025 To 2032
Forecast Period 2025 to 2032 CAGR:
10.80%
2032 Value Projection:
USD 25.36 Bn
Calcineurin inhibitors are a type of immunosuppressant. These drugs work by suppressing the activity of the immune system to prevent it from attacking the transplanted organ. They are commonly used in organ transplantation, especially kidney, heart, and liver transplants. There are two main types of calcineurin inhibitors: cyclosporine and tacrolimus. Both of these drugs have been proven to be effective in preventing organ rejection, but they can also have serious side effects, including kidney damage, high blood pressure, and an increased risk of infections and cancer. The global calcineurin inhibitors market is expected to grow due to the increasing prevalence of organ transplantation and autoimmune diseases. The market is also driven by the development of new drugs and the expansion of indications for existing drugs. However, the market growth may be hindered by the side effects of these drugs and the high cost of transplantation. Key players in the global calcineurin inhibitors market include Novartis AG, Astellas Pharma Inc., Allergan, Inc., and Pfizer Inc. These companies are focusing on research and development activities to develop new and improved calcineurin inhibitors. In terms of geography, North America holds the largest share of the calcineurin inhibitors market, followed by Europe. This is due to the high prevalence of organ transplantation and autoimmune diseases in these regions. The market in Asia Pacific is expected to grow at a significant rate due to the increasing healthcare expenditure and the growing awareness about organ transplantation in this region.
Market Dynamics:
Increasing cases of autoimmune diseases and organ transplantation is expected to drive growth of the global calcineurin inhibitor market in the near future. Increasing demand for the calcineurin inhibitors to prevent rejection of transplanted organs is the major driving factor. For instance, in December 2020, Biocon, an innovation-led global biopharmaceutical company, announced the launch of Tacrolimus capsules in the U.S. Tacrolimus is a calcineurin inhibitor, an immunosuppressant used in the treatment of organ transplant patients that reduces the body's ability to reject a transplanted organ.
However, side effects associated with calcineurin inhibitors such as skin irritation and gastrointestinal disturbances may hamper the market growth. Moreover, risks connected with overdosing of the orally administered drugs such as nephrotoxicity and hepatotoxicity are also expected to hamper the market growth in the near future.
Key features of the study:
This report provides in-depth analysis of the global calcineurin inhibitor market, and provides market size (US$ Bn) and compound annual growth rate (CAGR%) for the forecast period (2025-2032), considering 2024 as the base year
It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market
This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends, regional outlook, and competitive strategies adopted by key players
It profiles key players in the global calcineurin inhibitor market based on the following parameters-company highlights, products portfolio, key highlights, financial performance, and strategies
Key companies covered as a part of this study include Novartis AG, Amgen, F. Hoffmann-La Roche Ltd, Pfizer Inc., Incyte Corporation, Chiesi Farmaceutici S.p.A., Astellas Pharma Inc., Sanofi SA, Bristol Myers Squibb Company, Mylan N.V., Dr. Reddy's Laboratories Ltd., Senju Pharmaceutical Co. Ltd, Abbott, Lupin Limited, and Vibcare Pharma Pvt. Ltd.
Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future product launches, type up-gradation, market expansion, and marketing tactics
Global calcineurin inhibitor market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts
Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the global calcineurin inhibitor market
Detailed Segmentation:
Global Calcineurin Inhibitor Market, By Drug Type:
Cyclosporine
Tacrolimus
Pimecrolimus
Voclosporin
Others
Global Calcineurin Inhibitor Market, By Route of Administration:
Oral
Topical
Intravenous
Global Calcineurin Inhibitor Market, By Indication:
Organ Transplant Rejection Prevention
Autoimmune Diseases
Ophthalmic Diseases
Other Dermatological Conditions
Global Calcineurin Inhibitor Market, By Distribution Channel:
Hospital Pharmacies
Retail Pharmacies
Online Pharmacies
Global Calcineurin Inhibitor Market, By End User:
Hospitals
Specialty Clinics
Dermatology Centers
Transplant Centers
Global Calcineurin Inhibitor Market, By Region:
North America
Europe
Asia Pacific
Latin America
Middle East
Africa
Company Profiles:
Novartis AG
Amgen
F. Hoffmann-La Roche Ltd
Pfizer Inc.
Incyte Corporation
Chiesi Farmaceutici S.p.A.
Astellas Pharma Inc.
Sanofi SA
Bristol Myers Squibb Company
Mylan N.V.
Dr. Reddy's Laboratories Ltd.
Senju Pharmaceutical Co. Ltd
Abbott
Lupin Limited
Vibcare Pharma Pvt. Ltd.
Table of Contents
1. Research Objectives and Assumptions
Research Objectives
Assumptions
Abbreviations
2. Market Purview
Report Description
Market Definition and Scope
Executive Summary
Market Calcineurin Inhibitor, By Drug Type
Market Calcineurin Inhibitor, By Route of Administration
Market Calcineurin Inhibitor, By Indication
Market Calcineurin Inhibitor, By Distribution Channel
Market Calcineurin Inhibitor, By End User
Market Calcineurin Inhibitor, By Region
Coherent Opportunity Map (COM)
3. Market Dynamics, Regulations, and Trends Analysis
Market Dynamics
Drivers
Restraints
Opportunities
Impact Analysis
Key Highlights
Regulatory Scenario
Product Launches/Approvals
PEST Analysis
PORTER's Analysis
Merger and Acquisition Scenario
4. Global Calcineurin Inhibitor Market- Impact of Coronavirus (COVID-19) Pandemic
COVID-19 Epidemiology
Supply Side and Demand Side Analysis
Economic Impact
5. Global Calcineurin Inhibitor Market, By Drug Type, 2020-2032, (US$ Bn)
Introduction
Market Share Analysis, 2025 and 2032 (%)
Y-o-Y Growth Analysis, 2025 - 2032
Segment Trends
Cyclosporine
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (US$ Bn)
Tacrolimus
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (US$ Bn)
Pimecrolimus
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (US$ Bn)
Voclosporin
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (US$ Bn)
Others
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (US$ Bn)
6. Global Calcineurin Inhibitor Market, By Route of Administration, 2020-2032, (US$ Bn)
Introduction
Market Share Analysis, 2025 and 2032 (%)
Y-o-Y Growth Analysis, 2021- 2032
Segment Trends
Oral
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (US$ Bn)
Topical
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (US$ Bn)
Intravenous
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (US$ Bn)
7. Global Calcineurin Inhibitor Market, By Indication, 2020-2032, (US$ Bn)
Introduction
Market Share Analysis, 2025 and 2032 (%)
Y-o-Y Growth Analysis, 2021- 2032
Segment Trends
Organ Transplant Rejection Prevention
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (US$ Bn)
Autoimmune Diseases
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (US$ Bn)
Ophthalmic Diseases
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (US$ Bn)
Other Dermatological Conditions
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (US$ Bn)
8. Global Calcineurin Inhibitor Market, By Distribution Channel, 2020-2032, (US$ Bn)
Introduction
Market Share Analysis, 2025 and 2032 (%)
Y-o-Y Growth Analysis, 2021- 2032
Segment Trends
Hospital Pharmacies
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (US$ Bn)
Retail Pharmacies
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (US$ Bn)
Online Pharmacies
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (US$ Bn)
9. Global Calcineurin Inhibitor Market, By End User, 2020-2032, (US$ Bn)
Introduction
Market Share Analysis, 2023and 2032 (%)
Y-o-Y Growth Analysis, 2021- 2032
Segment Trends
Hospitals
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (US$ Bn)
Specialty Clinics
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (US$ Bn)
Dermatology Centers
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (US$ Bn)
Transplant Centers
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (US$ Bn)
10. Global Calcineurin Inhibitor Market, By Region, 2020-2032, (US$ Bn)
Introduction
Market Share Analysis, By Region, 2025 and 2032 (%)
Y-o-Y Growth Analysis, For Region, 2021 - 2032
Country Trends
North America
Introduction
Market Size and Forecast, and Y-o-Y Growth, By Drug Type, 2020-2032, (US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Route of Administration, 2020-2032, (US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Indication, 2020-2032, (US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Distribution Channel, 2020-2032, (US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By End User, 2020-2032, (US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Country, 2020-2032,(US$ Bn)
U.S.
Canada
Latin America
Introduction
Market Size and Forecast, and Y-o-Y Growth, By Drug Type, 2020-2032, (US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Route of Administration, 2020-2032, (US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Indication, 2020-2032, (US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Distribution Channel, 2020-2032, (US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By End User, 2020-2032, (US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Country, 2020-2032,(US$ Bn)
Brazil
Argentina
Mexico
Rest of Latin America
Europe
Introduction
Market Size and Forecast, and Y-o-Y Growth, By Drug Type, 2020-2032, (US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Route of Administration, 2020-2032, (US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Indication, 2020-2032, (US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Distribution Channel, 2020-2032, (US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By End User, 2020-2032, (US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Country, 2020-2032,(US$ Bn)
Germany
U.K.
Spain
France
Italy
Russia
Rest of Europe
Asia Pacific
Introduction
Market Size and Forecast, and Y-o-Y Growth, By Drug Type, 2020-2032, (US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Route of Administration, 2020-2032, (US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Indication, 2020-2032, (US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Distribution Channel, 2020-2032, (US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By End User, 2020-2032, (US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Country, 2020-2032,(US$ Bn)
China
India
Japan
Australia
South Korea
ASEAN
Rest of Asia Pacific
Middle East
Introduction
Market Size and Forecast, and Y-o-Y Growth, By Drug Type, 2020-2032, (US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Route of Administration, 2020-2032, (US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Indication, 2020-2032, (US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Distribution Channel, 2020-2032, (US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By End User, 2020-2032, (US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Country, 2020-2032,(US$ Bn)
GCC
Israel
Rest of Middle East
Africa
Introduction
Market Size and Forecast, and Y-o-Y Growth, By Drug Type, 2020-2032, (US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Route of Administration, 2020-2032, (US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Indication, 2020-2032, (US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Distribution Channel, 2020-2032, (US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By End User, 2020-2032, (US$ Bn)
Market Size and Forecast, and Y-o-Y Growth, By Country, 2020-2032,(US$ Bn)