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Single-Cell Genome Sequencing Global Market Report 2025
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Single-cell genome sequencing is a powerful method for detecting genomic changes such as copy number variations (CNVs) and point mutations, as well as revealing cell-to-cell heterogeneity in biological materials. It is employed to investigate both healthy and diseased physiology.

The main types of single-cell genome sequencing include instruments and reagents. Instruments refer to specialized equipment or devices used to perform the various steps involved in the sequencing process. Various technologies, such as next-generation sequencing (NGS), polymerase chain reaction (PCR), quantitative polymerase chain reaction (qPCR), microarray, and multiple displacement amplification (MDA), are utilized in disease areas such as cancer, immunology, prenatal diagnosis, neurobiology, microbiology, and others. The applications encompass circulating cells, cell differentiation or reprogramming, genomic variation, subpopulation characterization, and others, serving academic research laboratories, biotechnology biopharmaceutical companies, clinics, and other related entities.

Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report's Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.

The sharp rise in U.S. tariffs and the resulting trade tensions in spring 2025 are having a significant impact on the healthcare sector, especially in the supply of essential medical devices, diagnostic equipment, and pharmaceuticals. Hospitals and healthcare providers are grappling with higher costs for imported surgical tools, imaging systems, and consumables like syringes and catheters, many of which have limited domestic substitutes. These escalating expenses are putting pressure on healthcare budgets, prompting some providers to delay equipment upgrades or pass increased costs on to patients. Furthermore, tariffs on raw materials and components are disrupting the manufacturing of vital drugs and devices, leading to supply chain delays. In response, the industry is adopting diversified sourcing strategies, expanding local production where feasible, and pushing for tariff exemptions on critical medical products.

The single-cell genome sequencing market research report is one of a series of new reports from The Business Research Company that provides single-cell genome sequencing market statistics, including single-cell genome sequencing industry global market size, regional shares, competitors with a single-cell genome sequencing market share, detailed single-cell genome sequencing market segments, market trends and opportunities, and any further data you may need to thrive in the single-cell genome sequencing industry. This single-cell genome sequencing market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The single-cell genome sequencing market size has grown rapidly in recent years. It will grow from $2.49 billion in 2024 to $2.83 billion in 2025 at a compound annual growth rate (CAGR) of 13.6%. The growth in the historic period can be attributed to increased understanding of genetic heterogeneity, rising demand for precision medicine, increased cancer research, growth in prevalence of infectious diseases, increased healthcare spending.

The single-cell genome sequencing market size is expected to see rapid growth in the next few years. It will grow to $5.02 billion in 2029 at a compound annual growth rate (CAGR) of 15.4%. The growth in the forecast period can be attributed to increasing prevalence of autoimmune diseases, increasing neurological disorders, increasing government initiatives and funding, rise of contract research organizations (cros), increasing awareness of scrna-seq's potential. Major trends in the forecast period include advancements in single-cell sequencing technologies, development of single-cell multi-omics technologies, collaborative initiatives to accelerate advancements, innovative solutions, and key players' partnerships.

The forecast of 15.4% growth over the next five years reflects a slight reduction of 0.2% from the previous projection. This reduction is primarily due to the impact of tariffs between the US and other countries. Tariff barriers are expected to hamper the U.S. by increasing the cost of microfluidic single-cell isolation kits and barcoding reagents sourced from Israel and the UK, thereby slowing cancer heterogeneity studies and elevating research institution budgets. The effect will also be felt more widely due to reciprocal tariffs and the negative effect on the global economy and trade due to increased trade tensions and restrictions.

The anticipated rise in cancer prevalence is expected to drive the growth of the single-cell genome sequencing market in the future. Cancer, a diverse group of diseases characterized by uncontrolled cell growth, is a result of genetic changes affecting cell division and normal cellular functions. The disease is marked by genetic alterations, and single-cell genome sequencing proves invaluable in revealing these genetic changes at the individual cancer cell level. For example, in January 2023, the American Cancer Society reported approximately 1.9 million new cancer cases and 609,360 cancer-related deaths in the US in 2022. Predictions indicate a further increase, with an estimated 27.5 million new cancer cases and 16.3 million cancer deaths projected by 2040. Consequently, the rising incidence of cancer is expected to be a driving factor for the growth of the single-cell genome sequencing market.

The remarkable expansion of genomic data is a substantial contributor to the ongoing growth of the single-cell genome sequencing market. Genomic data encompasses information related to the structure and function of an organism's genome. The exponential increase in genomic data generated through single-cell sequencing opens up opportunities for data analysis, interpretation, and the development of bioinformatics tools, fostering market growth. As per a 2022 report from the National Human Genome Research Institute (NHGRI), the genomic data is projected to reach between 2 and 40 exabytes within the next decade. Hence, the rapid surge in genomic data is poised to propel the single-cell genome sequencing market.

Technological advancements emerge as a noteworthy trend gaining traction in the single-cell genome sequencing market. Leading companies in the sector are dedicated to developing technologically advanced solutions to enhance their market position. For instance, in May 2023, Mission Bio Inc., a US-based company specializing in single-cell multi-omics platforms, introduced the Tapestri Genome Editing Solution. This end-to-end product for genome editing analysis is expected to be a more effective analytical tool for developing next-generation gene-edited drugs, offering single-cell insights capable of impacting efficacy and safety.

Major players in the single-cell genome sequencing market are concentrating on the development of single-cell proteomics, a nascent discipline seeking to understand the diversity of protein expression within individual cells. Integrating single-cell genomics with proteomics techniques allows for studying the relationship between genomic information and protein expression at the single-cell level. For example, in October 2023, Proteome Sciences plc, a UK-based biotechnology company, launched SysQuant SCP, a single-cell proteomics commercial service. Leveraging the capabilities of its TMTpro isobaric labelling reagents, SysQuant SCP generates and analyzes quantitative mass spectrometry data to uncover subtle variations in individual cells and within subpopulations of the same primary cell type. This data is expected to advance our understanding of biological drivers of heterogeneity and evolution in disease contexts and therapy responses, providing new targets for personalized medicine.

In January 2023, Qiagen, a Germany-based pharmaceutical research company, acquired Verogen for an undisclosed amount. This acquisition aims to strengthen Qiagen's position in human identification and forensic testing by incorporating Verogen's NGS technology and expertise. Verogen is a biotechnology company based in the United States.

Major companies operating in the single-cell genome sequencing market include F Hoffmann-La Roche Ltd., Thermo Fisher Scientific Inc., DH Life Sciences LLC., Becton Dickinson And Company (BD), Agilent Technologies Inc., Illumina Inc., Bio-Rad Laboratories Inc., QIAGEN GmbH, Bio-Techne Corporation, BGI Genomics Co. Ltd., Fulgent Genetics Inc., 10x Genomics Inc., Promega Corporation, Takara Bio Inc., Oxford Nanopore Technologies PLC, Pacific Biosciences of California Inc., Standard BioTools Inc., Singleron Biotechnologies, MGI Tech Co. Ltd, GENEWIZ Inc., Mission Bio Inc., Zymo Research Corporation, Menarini Silicon Biosystems SpA, Novogene Co. Ltd., RareCyte Inc., Fluxion Biosciences Inc., Single Cell Discoveries B.V., Parse Biosciences Inc., BioSpyder Technologies Inc., SeqWell Inc.

North America was the largest region in the single-cell genome sequencing market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the single-cell genome sequencing market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa

The countries covered in the single-cell genome sequencing market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Italy, Spain, Canada.

The single-cell genome sequencing market consists of revenues earned by entities by providing single-cell analysis, genetic heterogeneity study, identification of genomes of individual cells, and microbiomes and cancer study. The market value includes the value of related goods sold by the service provider or included within the service offering. The single-cell genome sequencing market also includes sales of single cell kit, DNA sequencing instruments and single-cell sequencing kits. Values in this market are 'factory gate' values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

Single-Cell Genome Sequencing Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.

This report focuses on single-cell genome sequencing market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.

Reasons to Purchase

Where is the largest and fastest growing market for single-cell genome sequencing ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The single-cell genome sequencing market global report from the Business Research Company answers all these questions and many more.

The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.

The forecasts are made after considering the major factors currently impacting the market. These include the technological advancements such as AI and automation, Russia-Ukraine war, trade tariffs (government-imposed import/export duties), elevated inflation and interest rates.

Scope

Table of Contents

1. Executive Summary

2. Single-Cell Genome Sequencing Market Characteristics

3. Single-Cell Genome Sequencing Market Trends And Strategies

4. Single-Cell Genome Sequencing Market - Macro Economic Scenario Including The Impact Of Interest Rates, Inflation, Geopolitics, Trade Wars and Tariffs, And Covid And Recovery On The Market

5. Global Single-Cell Genome Sequencing Growth Analysis And Strategic Analysis Framework

6. Single-Cell Genome Sequencing Market Segmentation

7. Single-Cell Genome Sequencing Market Regional And Country Analysis

8. Asia-Pacific Single-Cell Genome Sequencing Market

9. China Single-Cell Genome Sequencing Market

10. India Single-Cell Genome Sequencing Market

11. Japan Single-Cell Genome Sequencing Market

12. Australia Single-Cell Genome Sequencing Market

13. Indonesia Single-Cell Genome Sequencing Market

14. South Korea Single-Cell Genome Sequencing Market

15. Western Europe Single-Cell Genome Sequencing Market

16. UK Single-Cell Genome Sequencing Market

17. Germany Single-Cell Genome Sequencing Market

18. France Single-Cell Genome Sequencing Market

19. Italy Single-Cell Genome Sequencing Market

20. Spain Single-Cell Genome Sequencing Market

21. Eastern Europe Single-Cell Genome Sequencing Market

22. Russia Single-Cell Genome Sequencing Market

23. North America Single-Cell Genome Sequencing Market

24. USA Single-Cell Genome Sequencing Market

25. Canada Single-Cell Genome Sequencing Market

26. South America Single-Cell Genome Sequencing Market

27. Brazil Single-Cell Genome Sequencing Market

28. Middle East Single-Cell Genome Sequencing Market

29. Africa Single-Cell Genome Sequencing Market

30. Single-Cell Genome Sequencing Market Competitive Landscape And Company Profiles

31. Single-Cell Genome Sequencing Market Other Major And Innovative Companies

32. Global Single-Cell Genome Sequencing Market Competitive Benchmarking And Dashboard

33. Key Mergers And Acquisitions In The Single-Cell Genome Sequencing Market

34. Recent Developments In The Single-Cell Genome Sequencing Market

35. Single-Cell Genome Sequencing Market High Potential Countries, Segments and Strategies

36. Appendix

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