세계의 신생항원 표적치료 시장 보고서(2025년)
Neoantigen Targeted Therapies Global Market Report 2025
상품코드 : 1824418
리서치사 : The Business Research Company
발행일 : On Demand Report
페이지 정보 : 영문 250 Pages
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한글목차

신생항원 표적치료 시장 규모는 향후 수년간 비약적인 성장이 예상됩니다. 2029년에는 CAGR 35.7%로 성장할 전망이며, 159억 3,000만 달러로 성장이 예측됩니다. 예측 기간의 성장은 바이오인포매틱스 진보, 프레시젼 메디신 확대, 신항원 백신 개발, 치료제의 병용 전략, 바이오마커의 검증 등에 기인하고 있습니다. 예측 기간 주요 동향에는 신생항원 내성 관리, 신생항원 프라이밍 입양 요법, 신생항원 기반 조합 요법, 실세계 데이터 통합, 예측 모델 강화 등이 포함됩니다.

향후 5년간의 성장률 35.7%라고 하는 예측은 전회 예측으로부터 0.1%라고 하는 미감소를 반영하고 있습니다. 이 감소는 주로 미국과 타국가 간 관세의 영향 때문입니다. 관세 장벽은 스위스나 일본에서 조달하는 개별화 암 백신과 시퀀싱 시약의 비용을 상승시키고 정밀 종양학의 진보를 늦추며, 면역 요법의 비용을 상승시킴으로써 미국을 저해할 것으로 예측됩니다. 또한 상호 관세와 무역 긴장 증가 및 제한으로 인한 세계 경제와 무역에 대한 악영향으로 그 영향이 더 광범위하게 늘어날 것으로 보입니다.

신생항원 표적치료 시장의 성장이 예상되는 주요 요인은 암 이환율 증가입니다. 이것은 일정 기간 동안 특정 집단 내에서 새롭게 발생하는 암 환자 증가를 의미합니다. 신생항원 표적치료는 종종 병용 투여되며 다양한 유형의 암 치료에 도움이 됩니다. 2022년 미국 암 협회는 미국에서 신규 암 증례의 대폭적인 증가를 보고해 190만 명에 달했습니다. 게다가 같은 해의 암에 의한 사망자수는 60만 9,360명으로, 이 병이 얼마나 심각한 영향을 미치고 있는지를 이야기하고 있습니다. 그 결과, 암 이환율의 급증이 신생항원 표적치료 시장의 성장을 가속하는 주요인이 되고 있습니다.

목차

제1장 주요 요약

제2장 시장 특징

제3장 시장 동향 및 전략

제4장 시장 : 금리, 인플레이션, 지정학, 무역전쟁 및 관세, 그리고 코로나 및 회복이 시장에 미치는 영향을 포함한 거시경제 시나리오

제5장 세계의 성장 분석 및 전략 분석 프레임워크

제6장 시장 세분화

제7장 지역별 및국가별 분석

제8장 아시아태평양 시장

제9장 중국 시장

제10장 인도 시장

제11장 일본 시장

제12장 호주 시장

제13장 인도네시아 시장

제14장 한국 시장

제15장 서유럽 시장

제16장 영국 시장

제17장 독일 시장

제18장 프랑스 시장

제19장 이탈리아 시장

제20장 스페인 시장

제21장 동유럽 시장

제22장 러시아 시장

제23장 북미 시장

제24장 미국 시장

제25장 캐나다 시장

제26장 남미 시장

제27장 브라질 시장

제28장 중동 시장

제29장 아프리카 시장

제30장 경쟁 구도 및 기업 프로파일

제31장 기타 주요 기업 및 혁신 기업

제32장 세계 시장 경쟁 벤치마킹 및 대시보드

제33장 주요 인수합병(M&A)

제34장 최근 시장 동향

제35장 시장의 잠재력이 높은 국가, 부문 및 전략

제36장 부록

AJY
영문 목차

영문목차

Neoantigen-targeted therapies represent a precision medicine approach focused on leveraging neoantigens within cancer cells. Neoantigens, distinct antigens arising from genetic abnormalities in cancer cells, become the target for harnessing the body's immune system to specifically identify and combat cancer.

These therapies fall into two main categories, monotherapy and combination therapy. Monotherapy involves utilizing a single medicine or therapeutic approach to address the disease. Immunotherapy options encompass DNA or RNA-based vaccines, protein-based vaccines, dendritic cell vaccines, and TIL-based therapies, with applications spanning colorectal cancer, renal cell carcinoma, non-small cell lung cancer, bone cancer, and gynecological cancer. Administration routes include intradermal, intravenous, and subcutaneous, while applications extend to medical research institutions, hospitals, clinics, and other healthcare settings.

Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report's Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.

The sharp rise in U.S. tariffs and the resulting trade tensions in spring 2025 are having a significant impact on the healthcare sector, especially in the supply of essential medical devices, diagnostic equipment, and pharmaceuticals. Hospitals and healthcare providers are grappling with higher costs for imported surgical tools, imaging systems, and consumables like syringes and catheters, many of which have limited domestic substitutes. These escalating expenses are putting pressure on healthcare budgets, prompting some providers to delay equipment upgrades or pass increased costs on to patients. Furthermore, tariffs on raw materials and components are disrupting the manufacturing of vital drugs and devices, leading to supply chain delays. In response, the industry is adopting diversified sourcing strategies, expanding local production where feasible, and pushing for tariff exemptions on critical medical products.

The neoantigen targeted therapies market research report is one of a series of new reports from The Business Research Company that provides neoantigen targeted therapies market statistics, including the neoantigen targeted therapies industry global market size, regional shares, competitors with a neoantigen targeted therapies market share, detailed neoantigen targeted therapies market segments, market trends, and opportunities, and any further data you may need to thrive in the neoantigen targeted therapies industry. This neoantigen targeted therapies market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The neoantigen targeted therapies market size has grown exponentially in recent years. It will grow from $3.4 billion in 2024 to $4.71 billion in 2025 at a compound annual growth rate (CAGR) of 38.3%. The growth in the historic period can be attributed to advancements in genomic sequencing, immunotherapy evolution, understanding tumor immunology, clinical success of checkpoint inhibitors, molecular profiling advancements.

The neoantigen targeted therapies market size is expected to see exponential growth in the next few years. It will grow to $15.93 billion in 2029 at a compound annual growth rate (CAGR) of 35.7%. The growth in the forecast period can be attributed to advancements in bioinformatics, precision medicine expansion, neoantigen vaccine development, therapeutic combination strategies, biomarker validation. Major trends in the forecast period include neoantigen resistance management, neoantigen-primed adoptive cell therapies, neoantigen-based combinatorial therapies, integration of real-world data, enhanced predictive models.

The forecast of 35.7% growth over the next five years reflects a slight reduction of 0.1% from the previous projection. This reduction is primarily due to the impact of tariffs between the US and other countries. Tariff barriers are expected to hamper the U.S. by increasing the cost of personalized cancer vaccines and sequencing reagents sourced from Switzerland and Japan, thereby delaying precision oncology advancements and elevating immunotherapy costs. The effect will also be felt more widely due to reciprocal tariffs and the negative effect on the global economy and trade due to increased trade tensions and restrictions.

The anticipated growth in the neoantigen targeted therapies market is primarily attributed to the increasing incidence of cancer cases. This refers to the rise in new cancer cases within a specific population during a given period. Neoantigen targeted therapies, often administered in combination, are instrumental in treating various types of cancer. In 2022, the American Cancer Society reported a substantial increase in new cancer cases in the United States, reaching 1.9 million. Additionally, 609,360 deaths were attributed to cancer in the same year, underscoring the profound impact of the disease. Consequently, the surge in cancer incidence is a key driver propelling the growth of the neoantigen targeted therapies market.

The increasing emphasis on precision oncology is expected to drive the growth of the neoantigen-targeted therapies market in the future. Precision oncology is a cancer treatment approach that utilizes detailed genetic and molecular information about a patient's tumor to guide the selection of targeted therapies. This approach employs neoantigen-targeted therapies by leveraging advanced genomic analysis to identify unique neoantigens expressed by an individual's cancer cells. The use of neoantigen-targeted therapies within precision oncology represents a strategy to tailor treatment to the specific genetic profile of each patient's tumor, providing a more personalized and effective treatment option. For instance, in March 2024, the Precision Oncology Clinical Trials & Statistics 2024 report published by Novotech, an Australia-based full-service clinical contract research organization focused on developing innovative therapeutics across all phases, noted that by November 2023, twelve treatments had received FDA approval for specific biomarker-selected indications, with six of these included in the NCCN guidelines. By the end of the year, 43% of the 217 FDA-approved oncology therapies were classified as precision oncology, with 78 of these therapies featuring DNA or NGS-detectable biomarkers, underscoring the growing importance of biomarker-driven treatments in cancer care. Thus, the rise in precision oncology is fueling the growth of the neoantigen-targeted therapies market.

Major companies in the neoantigen-targeted therapies market are pursuing a strategic partnership approach to personalize cancer therapies and address the challenges of existing immunotherapy in treating solid tumors. Strategic partnerships involve companies leveraging each other's strengths and resources to achieve mutual benefits and success. For example, in January 2023, BioNTech SE, a Germany-based biotechnology company, partnered with the Government of the United Kingdom to advance personalized mRNA cancer immunotherapies. This collaboration aims to deliver tailored treatments to as many as 10,000 patients by 2030, focusing on several critical areas, including the development of cancer immunotherapies, research on infectious disease vaccines, and the establishment of a research and development hub in Cambridge. The initiative will utilize the UK's clinical trial infrastructure and health data resources to enhance patient recruitment and select trial sites for BioNTech's mRNA treatments. The company plans to initiate its first clinical trials in the UK later this year, concentrating on cancer vaccines that could potentially be integrated into standard treatment protocols if proven effective.

Major companies in the neoantigen-targeted therapies market are adopting a strategic partnership approach to personalize neoantigen vaccines and monoclonal antibody drugs to tackle the challenges of existing immunotherapy in treating solid tumors. Strategic partnerships involve companies leveraging each other's strengths and resources for mutual benefit and success. For instance, in April 2023, Moderna, Inc., a US-based pharmaceutical and biotechnology company, collaborated with Merck & Co., Inc., a US-based pharmaceutical company, to launch mRNA-4157 (V940). This investigational individualized neoantigen therapy (INT) is designed to generate a tailored antitumor immune response based on the unique mutational signature of a patient's tumor. mRNA-4157 (V940) works by encoding up to 34 neoantigens to stimulate T cell responses, enhancing the body's ability to target and destroy tumor cells when combined with Merck's immunotherapy KEYTRUDA. This combination aims to improve recurrence-free survival in patients with high-risk resected melanoma.

In January 2023, AstraZeneca plc, a UK-based pharmaceutical company, acquired Neogene Therapeutics Inc. for $200 million. This acquisition is intended to enhance AstraZeneca's oncology portfolio, with a particular focus on developing transformative T-cell receptor (TCR) therapies that target neoantigens in solid tumors. Neogene's expertise in next-generation TCR-T therapies is expected to complement AstraZeneca's existing capabilities in the oncology field, allowing the company to advance its cancer treatment initiatives. Neogene Therapeutics Inc. is a US-based biotechnology company that specializes in neoantigen-targeted therapies.

Major companies operating in the neoantigen targeted therapies market include F. Hoffmann-La Roche AG, Merck and Co. Inc., Bristol Myers Squibb Company, Eli Lilly and Company, Kite Pharma Inc., Gilead Sciences Inc., Amgen Inc., Moderna Inc., BioNTech SE, Bavarian Nordic Inc., Advaxis Inc., Immatics NV, Precision Biologics Inc., Iovance Biotherapeutics Inc., Agenus Inc., Achilles Therapeutics Plc, Medigene AG, Gritstone Bio Inc., SQZ Biotechnologies Company, Aduro BioTech Inc., Inovio Pharmaceuticals Inc., Gradalis Inc., EpiVax Inc., ISA Pharmaceuticals BV, Vaxon Biotech SA, Ziopharm Oncology, Genocea Biosciences Inc., Cellular Biomedicine Group Inc., Immunovaccine Inc.

North America was the largest region in the neoantigen targeted therapies market in 2024. The regions covered in the neoantigen targeted therapies market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

The countries covered in the neoantigen targeted therapies market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

The neoantigen targeted therapies market consists of revenues earned by entities by providing services such as the identification and characterization of neoantigens in individual patients, the selection and administration of the appropriate therapy, and the monitoring of patients' responses. The market value includes the value of related goods sold by the service provider or included within the service offering. Neoantigen targeted therapies also include the sale of neoantigen-based cancer vaccines and genetically modified T cells. Values in this market are 'factory gate' values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

Neoantigen Targeted Therapies Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.

This report focuses on neoantigen targeted therapies market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.

Reasons to Purchase

Where is the largest and fastest growing market for neoantigen targeted therapies ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The neoantigen targeted therapies market global report from the Business Research Company answers all these questions and many more.

The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.

The forecasts are made after considering the major factors currently impacting the market. These include the technological advancements such as AI and automation, Russia-Ukraine war, trade tariffs (government-imposed import/export duties), elevated inflation and interest rates.

Scope

Table of Contents

1. Executive Summary

2. Neoantigen Targeted Therapies Market Characteristics

3. Neoantigen Targeted Therapies Market Trends And Strategies

4. Neoantigen Targeted Therapies Market - Macro Economic Scenario Including The Impact Of Interest Rates, Inflation, Geopolitics, Trade Wars and Tariffs, And Covid And Recovery On The Market

5. Global Neoantigen Targeted Therapies Growth Analysis And Strategic Analysis Framework

6. Neoantigen Targeted Therapies Market Segmentation

7. Neoantigen Targeted Therapies Market Regional And Country Analysis

8. Asia-Pacific Neoantigen Targeted Therapies Market

9. China Neoantigen Targeted Therapies Market

10. India Neoantigen Targeted Therapies Market

11. Japan Neoantigen Targeted Therapies Market

12. Australia Neoantigen Targeted Therapies Market

13. Indonesia Neoantigen Targeted Therapies Market

14. South Korea Neoantigen Targeted Therapies Market

15. Western Europe Neoantigen Targeted Therapies Market

16. UK Neoantigen Targeted Therapies Market

17. Germany Neoantigen Targeted Therapies Market

18. France Neoantigen Targeted Therapies Market

19. Italy Neoantigen Targeted Therapies Market

20. Spain Neoantigen Targeted Therapies Market

21. Eastern Europe Neoantigen Targeted Therapies Market

22. Russia Neoantigen Targeted Therapies Market

23. North America Neoantigen Targeted Therapies Market

24. USA Neoantigen Targeted Therapies Market

25. Canada Neoantigen Targeted Therapies Market

26. South America Neoantigen Targeted Therapies Market

27. Brazil Neoantigen Targeted Therapies Market

28. Middle East Neoantigen Targeted Therapies Market

29. Africa Neoantigen Targeted Therapies Market

30. Neoantigen Targeted Therapies Market Competitive Landscape And Company Profiles

31. Neoantigen Targeted Therapies Market Other Major And Innovative Companies

32. Global Neoantigen Targeted Therapies Market Competitive Benchmarking And Dashboard

33. Key Mergers And Acquisitions In The Neoantigen Targeted Therapies Market

34. Recent Developments In The Neoantigen Targeted Therapies Market

35. Neoantigen Targeted Therapies Market High Potential Countries, Segments and Strategies

36. Appendix

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