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Oncology Based In-Vivo CRO Global Market Report 2025
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An oncology-focused in-vivo contract research organization (CRO) is a company contracted by another entity to conduct various stages of preclinical in-vivo studies for oncology drugs or devices. This includes designing, overseeing, monitoring, and analyzing preclinical in-vivo research involving living organisms such as animals, plants, or cells.

The primary areas of focus for oncology-based in-vivo CROs encompass blood cancer, solid tumors, and other related indications. Blood cancers originate from tissues responsible for blood formation, such as immune cells and bone marrow, including leukemia, lymphoma, and multiple myeloma. These CROs provide in-vivo testing services utilizing models such as blood cancer-based xenografts and others to expedite drug development research, aiding sponsors of drugs and devices in gaining market approval. Various models, including syngeneic, xenograft, patient-derived xenograft (PDX), and others, are employed by oncology-based in-vivo CROs and applied within hospital and rehabilitation settings.

Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report's Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.

The sharp rise in U.S. tariffs and the resulting trade tensions in spring 2025 are having a significant impact on the healthcare sector, especially in the supply of essential medical devices, diagnostic equipment, and pharmaceuticals. Hospitals and healthcare providers are grappling with higher costs for imported surgical tools, imaging systems, and consumables like syringes and catheters, many of which have limited domestic substitutes. These escalating expenses are putting pressure on healthcare budgets, prompting some providers to delay equipment upgrades or pass increased costs on to patients. Furthermore, tariffs on raw materials and components are disrupting the manufacturing of vital drugs and devices, leading to supply chain delays. In response, the industry is adopting diversified sourcing strategies, expanding local production where feasible, and pushing for tariff exemptions on critical medical products.

The oncology based in-vivo CRO software market research report is one of a series of new reports from The Business Research Company that provides oncology based in-vivo CRO software market statistics, including oncology based in-vivo CRO software industry global market size, regional shares, competitors with a oncology based in-vivo CRO software market share, detailed oncology based in-vivo CRO software market segments, market trends and opportunities, and any further data you may need to thrive in the oncology based in-vivo CRO software industry. This oncology based in-vivo CRO software market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The oncology based in-vivo cro market size has grown strongly in recent years. It will grow from $1.39 billion in 2024 to $1.5 billion in 2025 at a compound annual growth rate (CAGR) of 7.7%. The growth in the historic period can be attributed to increasing focus on oncology therapeutics, increasing incidence of cancer, shift towards personalized medicine, pharmaceutical industry growth, and demand for target-specific therapies.

The oncology based in-vivo cro market size is expected to see rapid growth in the next few years. It will grow to $2.27 billion in 2029 at a compound annual growth rate (CAGR) of 10.9%. The growth in the forecast period can be attributed to emerging market opportunities, a shift towards immuno-oncology therapies, a rise in oncology clinical trials, precision medicine, and targeted therapies. Major trends in the forecast period include regenerative medicine and cell therapies, demand for faster drug development, digitalization and data analytics, focus on tumor microenvironment, and rise in biologics and immunotherapies.

The forecast of 10.9% growth over the next five years reflects a slight reduction of 0.2% from the previous projection. This reduction is primarily due to the impact of tariffs between the US and other countries. The imposition of tariffs may pose challenges for U.S. clinical trials by raising costs for PDX mouse models (China) and microimaging scanners (Netherlands), potentially delaying oncology drug approvals and increasing research and development (R&D) expenditures. The effect will also be felt more widely due to reciprocal tariffs and the negative effect on the global economy and trade due to increased trade tensions and restrictions.

The increasing incidence of cancer is projected to drive growth in the oncology-based in-vivo contract research organization (CRO) market in the future. Cancer is characterized by a group of diseases where abnormal cells divide uncontrollably, invade surrounding tissues, and can spread to other parts of the body via the blood and lymphatic systems. Effective cancer diagnosis and treatment necessitate innovative drugs and devices that undergo various preclinical trials, clinical trials, and regulatory processes before they can reach the market. An oncology in-vivo CRO is a company contracted by a sponsor to provide research services, including conducting all or part of the steps involved in preclinical in-vivo studies (testing on living organisms such as animals, plants, or whole cells) prior to human trials. As the prevalence of cancer continues to rise, the demand for innovative treatments and therapies is also increasing, thereby propelling the growth of the oncology-based in-vivo CRO market. For example, the American Cancer Society, a non-profit organization based in the U.S., reported approximately 609,000 cancer-related deaths and 1.9 million new cancer cases identified in the country in 2022. In 2024, an estimated 620,000 cancer deaths are anticipated, reflecting a slight increase in mortality rates. Consequently, the rising prevalence of cancer is driving growth in the oncology-based in-vivo CRO market.

The upsurge in healthcare spending is expected to drive the expansion of the oncology-based in-vitro CRO market. Healthcare expenditure, encompassing costs related to healthcare services, significantly influences the development and accessibility of in-vitro CRO services within the oncology sector. Notably, the Canadian Institute for Health Information reported a rise in healthcare expenditure to $331 billion in 2022, indicating an 0.8% increase from the previous year. This surge in spending accentuates the market's growth within the oncology-based in-vitro CRO domain.

Leading companies in the oncology-based in-vivo CRO market are increasingly focusing on personalized oncology models to establish a competitive edge. These personalized oncology models leverage patient-derived xenografts (PDXs) to develop customized treatment strategies, thereby improving the relevance and effectiveness of preclinical studies. For example, in 2022, Charles River Laboratories, a life sciences company based in the U.S., introduced its OncoMouse platform, which utilizes PDX technology for more precise tumor modeling. This platform offers high-throughput screening capabilities and real-time monitoring of tumor growth, facilitating quick evaluations of therapeutic responses. Furthermore, it includes integrated data analytics to refine treatment protocols according to individual patient profiles. These developments represent a significant shift toward more effective and patient-focused methods in cancer research.

Companies within this market segment are focusing on novel solutions such as CAR T-cell therapies to gain a competitive edge. For instance, Seattle Children's Hospital and Research Institute launched BrainChild Bio in May 2023, targeting CAR T-cell therapies for pediatric brain tumors such as diffuse intrinsic pontine gliomas (DIPG). This platform incorporates synthetic technologies to enhance CAR T-cell therapy for CNS malignancies, aiming to expand its applications to other challenging brain tumors such as glioblastoma and brain metastases. The pursuit of these innovative therapies signifies a strategic move to advance treatment options within the oncology-based in-vivo CRO market.

In March 2023, ClinChoice Medical Development, a US-based contract research organization (CRO) that provides research services to accelerate drug and device approvals, acquired Cromsource S.r.l. for an undisclosed amount. Through this acquisition, ClinChoice Medical Development expands its operational capabilities with additional delivery hubs to complement its existing network in Europe and the US. Data science technology offerings in several areas, including risk-based monitoring and decentralized clinical trials, are expanded through acquisition. Cromsource S.r.l. is an Italy-based contract research organization that provides full-research services to the pharmaceutical, biotechnology, and medical device industries.

Major companies operating in the oncology based in-vivo cro market include Crown Bioscience, Charles River Laboratories International Inc., Taconic Biosciences Inc., The Jackson Laboratory, ICON plc., WuXi AppTec Inc., Eurofins Scientific SE, Labcorp Drug Development, Champion Oncology Inc., Xentech SAS, Thermo Fisher Scientific Inc., MI Bioresearch Inc., Clintec International Private Limited, Worldwide Clinical Trials Inc., Pharm-Olam LLC, Clinipace Clinical Research Private Limited, Covance Inc., Evotec SE, Living Tumor Laboratory, Oncodesign SA, Pharmaron Beijing Co. Ltd., Syngene International Limited, GenScript Biotech Corporation, Shanghai Medicilon Inc., Oncolys BioPharma Inc., Pharmalegacy Laboratories, Oncotest GmbH, Oncovision, Biocytogen LLC, Innovent Biologics Inc.

North America was the largest region in the oncology based in-vivo CRO market in 2024. North America is expected to be the fastest-growing region in the global oncology-based in-vivo CRO market report during the forecast period. The regions covered in the oncology based in-vivo cro market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa

The countries covered in the oncology based in-vivo cro market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain

The oncology-based in-vivo CRO market includes revenues earned by entities by providing preclinical research services such as in-vivo testing via models such as Orthotopic tumor models, tumor passaging, tissue culture models, and others for oncology drugs and devices. The market value includes the value of related goods sold by the service provider or included within the service offering. Only goods and services traded between entities or sold to end consumers are included.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

Oncology Based In-Vivo CRO Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.

This report focuses on oncology based in-vivo cro market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.

Reasons to Purchase

Where is the largest and fastest growing market for oncology based in-vivo cro ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The oncology based in-vivo cro market global report from the Business Research Company answers all these questions and many more.

The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.

The forecasts are made after considering the major factors currently impacting the market. These include the technological advancements such as AI and automation, Russia-Ukraine war, trade tariffs (government-imposed import/export duties), elevated inflation and interest rates.

Scope

Table of Contents

1. Executive Summary

2. Oncology Based In-Vivo CRO Market Characteristics

3. Oncology Based In-Vivo CRO Market Trends And Strategies

4. Oncology Based In-Vivo CRO Market - Macro Economic Scenario Including The Impact Of Interest Rates, Inflation, Geopolitics, Trade Wars and Tariffs, And Covid And Recovery On The Market

5. Global Oncology Based In-Vivo CRO Growth Analysis And Strategic Analysis Framework

6. Oncology Based In-Vivo CRO Market Segmentation

7. Oncology Based In-Vivo CRO Market Regional And Country Analysis

8. Asia-Pacific Oncology Based In-Vivo CRO Market

9. China Oncology Based In-Vivo CRO Market

10. India Oncology Based In-Vivo CRO Market

11. Japan Oncology Based In-Vivo CRO Market

12. Australia Oncology Based In-Vivo CRO Market

13. Indonesia Oncology Based In-Vivo CRO Market

14. South Korea Oncology Based In-Vivo CRO Market

15. Western Europe Oncology Based In-Vivo CRO Market

16. UK Oncology Based In-Vivo CRO Market

17. Germany Oncology Based In-Vivo CRO Market

18. France Oncology Based In-Vivo CRO Market

19. Italy Oncology Based In-Vivo CRO Market

20. Spain Oncology Based In-Vivo CRO Market

21. Eastern Europe Oncology Based In-Vivo CRO Market

22. Russia Oncology Based In-Vivo CRO Market

23. North America Oncology Based In-Vivo CRO Market

24. USA Oncology Based In-Vivo CRO Market

25. Canada Oncology Based In-Vivo CRO Market

26. South America Oncology Based In-Vivo CRO Market

27. Brazil Oncology Based In-Vivo CRO Market

28. Middle East Oncology Based In-Vivo CRO Market

29. Africa Oncology Based In-Vivo CRO Market

30. Oncology Based In-Vivo CRO Market Competitive Landscape And Company Profiles

31. Oncology Based In-Vivo CRO Market Other Major And Innovative Companies

32. Global Oncology Based In-Vivo CRO Market Competitive Benchmarking And Dashboard

33. Key Mergers And Acquisitions In The Oncology Based In-Vivo CRO Market

34. Recent Developments In The Oncology Based In-Vivo CRO Market

35. Oncology Based In-Vivo CRO Market High Potential Countries, Segments and Strategies

36. Appendix

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