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Oral Antidiabetic Drugs Global Market Report 2025
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Oral antidiabetic drugs are medications taken orally to help regulate and control blood sugar levels in people with type 2 diabetes. These drugs act through different mechanisms, including enhancing insulin sensitivity, promoting insulin secretion, or decreasing glucose production in the liver. They play a crucial role in diabetes management to prevent complications and support long-term health.

The primary classes of oral antidiabetic drugs include biguanides, dipeptidyl peptidase-4 inhibitors, sodium-glucose cotransporter-2 inhibitors, sulfonylureas, thiazolidinediones, meglitinides, alpha-glucosidase inhibitors, among others. Biguanides specifically lower blood glucose mainly by reducing liver glucose production and increasing insulin sensitivity. These medications can be administered orally, sublingually, or buccally, and are used to treat conditions such as type 2 diabetes, gestational diabetes, and type 1 diabetes. They are distributed through various channels including hospital pharmacies, retail pharmacies, online pharmacies, and more, with key end users comprising hospitals, pharmacy stores, drugstores, diabetes treatment centers, and others.

Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report's Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.

The sudden escalation of U.S. tariffs and the consequent trade frictions in spring 2025 are severely impacting the pharmaceutical companies contend with tariffs on APIs, glass vials, and lab equipment inputs with few alternative sources. Generic drug makers, operating on razor-thin margins, are especially vulnerable, with some reducing production of low-profit medicines. Biotech firms face delays in clinical trials due to tariff-related shortages of specialized reagents. In response, the industry is expanding API production in India and Europe, increasing inventory stockpiles, and pushing for trade exemptions for essential medicines.

The oral antidiabetic drugs market research report is one of a series of new reports from The Business Research Company that provides oral antidiabetic drugs market statistics, including the oral antidiabetic drugs industry global market size, regional shares, competitors with the oral antidiabetic drugs market share, detailed oral antidiabetic drugs market segments, market trends, and opportunities, and any further data you may need to thrive in the oral antidiabetic drugs industry. This oral antidiabetic drugs market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.

The oral antidiabetic drug market size has grown strongly in recent years. It will grow from $62.25 billion in 2024 to $66.73 billion in 2025 at a compound annual growth rate (CAGR) of 7.2%. The growth during the historic period can be attributed to the rising prevalence of diabetes, growing awareness of diabetes management, an expanding elderly population, increased availability of advanced oral antidiabetic formulations, and the development of healthcare infrastructure.

The oral antidiabetic drugs market size is expected to see strong growth in the next few years. It will grow to $86.92 billion in 2029 at a compound annual growth rate (CAGR) of 6.8%. The anticipated growth in the forecast period can be linked to the growing adoption of novel oral antidiabetic therapies, increased investments in diabetes research and development, rising demand for affordable diabetes treatments, the global surge in type 2 diabetes prevalence, and a stronger emphasis on personalized medicine in diabetes care. Key trends expected during this time include advancements in drug delivery technologies, innovations in combination therapies, incorporation of digital health tools for diabetes management, development of safer and more effective oral antidiabetic drugs, and progress in personalized treatment strategies.

The rising incidence of type 2 diabetes is expected to drive the growth of the oral antidiabetic drugs market in the coming years. Type 2 diabetes is a chronic condition characterized by the body's resistance to insulin or insufficient insulin production needed to regulate normal blood glucose levels. The increase in type 2 diabetes cases is largely due to rising obesity rates, as excess body fat leads to insulin resistance and disrupted glucose metabolism. Oral antidiabetic drugs help manage type 2 diabetes by improving insulin sensitivity, boosting insulin secretion, or decreasing glucose production and absorption, thereby maintaining healthy blood sugar levels. For example, in March 2025, the Office for Health Improvement and Disparities, a UK government agency, reported that the prevalence of type 2 diabetes among adults aged 17 and older in England rose to 7.0%, up from 6.8% in March 2023. Consequently, the growing prevalence of type 2 diabetes is fueling the expansion of the oral antidiabetic drugs market.

Key players in the oral antidiabetic drugs market are focusing on clinical trials to develop safer and more effective treatments, expand their product lines, and secure regulatory approvals for next-generation therapies. Clinical trials are controlled studies involving human participants to assess the safety, efficacy, and side effects of new drugs or medical interventions. For instance, in April 2025, Eli Lilly and Company, a US-based pharmaceutical firm, launched Orforglipron, a once-daily oral small-molecule GLP-1 receptor agonist designed to simplify diabetes management, following a successful phase 3 trial. This oral medication aims to provide similar efficacy and safety to injectable therapies while improving patient compliance. In clinical trials, Orforglipron reduced HbA1c levels (a measure of blood sugar control) by an average of 1.3% to 1.6% across various doses over 40 weeks.

In January 2024, Roche Group, a Switzerland-based pharmaceutical company, acquired Carmot Therapeutics Inc. for an undisclosed sum. This acquisition was intended to strengthen Roche's pipeline in obesity and diabetes treatments by gaining access to Carmot Therapeutics' innovative small-molecule drugs targeting incretin biology. Carmot Therapeutics, based in the US, is developing oral antidiabetic drugs including CT-996, a once-daily oral small-molecule GLP-1 receptor agonist.

Major players in the oral antidiabetic drugs market are Pfizer Inc., Johnson & Johnson, F. Hoffmann-La Roche Ltd., Merck & Co. Inc., Bayer AG, Novartis AG, Sanofi S.A., Bristol-Myers Squibb Company, AstraZeneca plc, Abbott Laboratories, GlaxoSmithKline plc, Takeda Pharmaceutical Company Limited, Eli Lilly and Company, Novo Nordisk A/S, C.H. Boehringer Sohn AG & Co. KG, Viatris Inc., Teva Pharmaceutical Industries Limited, Astellas Pharma Inc., Sun Pharmaceutical Industries Limited, Cipla Limited.

North America was the largest region in the oral antidiabetic drugs market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in oral antidiabetic drugs report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

The countries covered in the oral antidiabetic drugs market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

The oral antidiabetic drugs market consists of sales of dual or combination oral therapies, glucokinase activators, and amylin analogs. Values in this market are 'factory gate' values, that is, the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).

The revenues for a specified geography are consumption values and are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

Oral Antidiabetic Drugs Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.

This report focuses on oral antidiabetic drugs market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.

Reasons to Purchase

Where is the largest and fastest growing market for oral antidiabetic drugs ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The oral antidiabetic drugs market global report from the Business Research Company answers all these questions and many more.

The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.

The forecasts are made after considering the major factors currently impacting the market. These include the technological advancements such as AI and automation, Russia-Ukraine war, trade tariffs (government-imposed import/export duties), elevated inflation and interest rates.

Scope

Table of Contents

1. Executive Summary

2. Oral Antidiabetic Drugs Market Characteristics

3. Oral Antidiabetic Drugs Market Trends And Strategies

4. Oral Antidiabetic Drugs Market - Macro Economic Scenario Including The Impact Of Interest Rates, Inflation, Geopolitics, Trade Wars and Tariffs, And Covid And Recovery On The Market

5. Global Oral Antidiabetic Drugs Growth Analysis And Strategic Analysis Framework

6. Oral Antidiabetic Drugs Market Segmentation

7. Oral Antidiabetic Drugs Market Regional And Country Analysis

8. Asia-Pacific Oral Antidiabetic Drugs Market

9. China Oral Antidiabetic Drugs Market

10. India Oral Antidiabetic Drugs Market

11. Japan Oral Antidiabetic Drugs Market

12. Australia Oral Antidiabetic Drugs Market

13. Indonesia Oral Antidiabetic Drugs Market

14. South Korea Oral Antidiabetic Drugs Market

15. Western Europe Oral Antidiabetic Drugs Market

16. UK Oral Antidiabetic Drugs Market

17. Germany Oral Antidiabetic Drugs Market

18. France Oral Antidiabetic Drugs Market

19. Italy Oral Antidiabetic Drugs Market

20. Spain Oral Antidiabetic Drugs Market

21. Eastern Europe Oral Antidiabetic Drugs Market

22. Russia Oral Antidiabetic Drugs Market

23. North America Oral Antidiabetic Drugs Market

24. USA Oral Antidiabetic Drugs Market

25. Canada Oral Antidiabetic Drugs Market

26. South America Oral Antidiabetic Drugs Market

27. Brazil Oral Antidiabetic Drugs Market

28. Middle East Oral Antidiabetic Drugs Market

29. Africa Oral Antidiabetic Drugs Market

30. Oral Antidiabetic Drugs Market Competitive Landscape And Company Profiles

31. Oral Antidiabetic Drugs Market Other Major And Innovative Companies

32. Global Oral Antidiabetic Drugs Market Competitive Benchmarking And Dashboard

33. Key Mergers And Acquisitions In The Oral Antidiabetic Drugs Market

34. Recent Developments In The Oral Antidiabetic Drugs Market

35. Oral Antidiabetic Drugs Market High Potential Countries, Segments and Strategies

36. Appendix

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