Advanced therapy medicinal products are medicines derived from genes, cells, or tissue engineering that provide innovative treatments for a variety of diseases and injuries. These therapies function by repairing, replacing, or regenerating human cells, tissues, or organs to restore normal function.
The main types of advanced therapy medicinal products include somatic cell therapy medicinal products, tissue-engineered medicinal products, and gene therapy medicinal products. Somatic cell therapy medicinal products involve treatments using cells from the human body (excluding reproductive cells) that are manipulated or processed to treat, prevent, or cure diseases by repairing or replacing damaged tissues or cells. These therapies employ various technologies such as gene editing, viral vector technology, stem cell technology, and automation and artificial intelligence-driven processes. They are used in treating conditions including muscular dystrophies, Alzheimer's, hemophilia, cystic fibrosis, among others. Distribution channels include hospital pharmacies, retail pharmacies, and online pharmacies, serving a wide range of end users such as hospitals, specialty clinics, and other healthcare providers.
Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report's Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.
The sudden escalation of U.S. tariffs and the consequent trade frictions in spring 2025 are severely impacting the pharmaceutical companies contend with tariffs on APIs, glass vials, and lab equipment inputs with few alternative sources. Generic drug makers, operating on razor-thin margins, are especially vulnerable, with some reducing production of low-profit medicines. Biotech firms face delays in clinical trials due to tariff-related shortages of specialized reagents. In response, the industry is expanding API production in India and Europe, increasing inventory stockpiles, and pushing for trade exemptions for essential medicines.
The advanced therapy medicinal products market research report is one of a series of new reports from The Business Research Company that provides advanced therapy medicinal products market statistics, including advanced therapy medicinal products global market size, regional shares, competitors with advanced therapy medicinal products market share, detailed advanced therapy medicinal products market segments, market trends and opportunities, and any further data you may need to thrive in the advanced therapy medicinal products industry. The advanced therapy medicinal products market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.
The advanced therapy medicinal products market size has grown rapidly in recent years. It will grow from $42.85 billion in 2024 to $51.34 billion in 2025 at a compound annual growth rate (CAGR) of 19.8%. The growth during the historic period can be attributed to the increasing number of clinical trials for gene and cell therapies, the rising incidence of rare and genetic disorders, growing demand for curative treatments rather than chronic disease management, improving success rates of early-phase clinical studies, and the increasing prevalence of chronic and age-related conditions.
The advanced therapy medicinal products market size is expected to see rapid growth in the next few years. It will grow to $104.43 billion in 2029 at a compound annual growth rate (CAGR) of 19.4%. The growth in the forecast period can be attributed to the increasing demand for personalized and precision medicine approaches, a rising pipeline of chimeric antigen receptor T-cell and gene-editing therapies, growing adoption of precision medicine and genomics, increasing healthcare expenditure in emerging markets, and a heightened focus on decentralized clinical trial models. Key trends during the forecast period include the development of allogeneic off-the-shelf therapies, advancements in non-viral gene delivery vectors, integration of digital twins in therapy simulation, implementation of blockchain in supply chain tracking, and innovations in 3D bioprinting for tissue engineering.
The increasing demand for personalized medicine is anticipated to drive the growth of the advanced therapy medicinal products market in the coming years. Personalized medicine is a healthcare approach that customizes treatment and prevention strategies based on an individual's unique genetic profile, lifestyle, and environment. This rising demand is largely due to the growing prevalence of chronic diseases, as personalized treatments improve patient outcomes and minimize side effects. Advanced therapy medicinal products support personalized medicine by providing tailored treatments such as gene, cell, and tissue-engineered therapies that specifically target the unique genetic and biological characteristics of individual patients. In February 2024, the Personalized Medicine Coalition, a US-based nonprofit organization, reported that the FDA approved 16 new personalized treatments for rare disease patients in 2023, up from six in 2022. These approvals also included seven cancer drugs and three treatments for other diseases and conditions. Thus, the growing demand for personalized medicine is fueling the expansion of the advanced therapy medicinal products market.
Key players in the advanced therapy medicinal products market are concentrating on innovative therapies like new CAR-T cell therapies to enhance treatment outcomes for cancer and other severe diseases. CAR-T cell therapies are advanced cancer treatments that use a patient's own T cells, genetically modified to identify and destroy cancer cells. For example, in May 2022, Novartis AG, a Switzerland-based pharmaceutical company, received FDA approval for Kymriah, a CAR-T cell therapy intended for adult patients with relapsed or refractory follicular lymphoma (FL) after two or more prior systemic therapies. This treatment involves genetically engineering the patient's T cells to express a chimeric antigen receptor (CAR) that targets the CD19 protein, enabling the T cells to recognize and eliminate malignant B cells. Kymriah also includes a 4-1BB costimulatory domain, which supports T cell expansion and persistence, resulting in prolonged antitumor effects from a single infusion.
In May 2024, Tri-Tech Forensics Inc., a US-based forensic company, acquired SAM Medical Products for an undisclosed sum. This acquisition is expected to help Tri-Tech Forensics broaden its emergency medical product portfolio and reinforce its market position. SAM Medical Products is a US-based firm specializing in the development, manufacturing, and marketing of orthopedic splints, wound care devices, and medical service products designed for various healthcare professionals.
Major players in the advanced therapy medicinal products market are F. Hoffmann-La Roche Limited., Novartis AG, Bristol-Myers Squibb Company, Takeda Pharmaceutical Company Limited., Lonza Group AG, Catalent Inc., BioMarin Pharmaceutical Inc., AGC Biologics Inc., ViaCyte Inc., Rentschler Biopharma SE, JCR Pharmaceuticals Co. Ltd., Vericel Corporation, UniQure N.V., Fate Therapeutics Inc., WuXi Advanced Therapies Inc., Celonic Group AG, Pharmicell Co. Ltd., Magenta Therapeutics Inc, MEDIPOST Co. Ltd., and Kolon TissueGene Inc.
North America was the largest region in the advanced therapy medicinal products market in 2024. Asia Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in advanced therapy medicinal products report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.
The countries covered in the advanced therapy medicinal products market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
The advanced therapy medicinal products market consists of revenues earned by entities by providing services such as cell and gene therapy development services, viral vector production and characterization, regulatory and clinical trial support, analytical testing and quality control services, and process development and scale-up services. The market value includes the value of related goods sold by the service provider or included within the service offering. The advanced therapy medicinal products market also includes sales of gene therapy vectors, engineered tissue scaffolds, bioengineered skin substitutes, and encapsulated cell therapies. Values in this market are 'factory gate' values; that is, the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).
The revenues for a specified geography are consumption values and are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
Advanced Therapy Medicinal Products Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.
This report focuses on advanced therapy medicinal products market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
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Where is the largest and fastest growing market for advanced therapy medicinal products ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The advanced therapy medicinal products market global report from the Business Research Company answers all these questions and many more.
The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.
The market characteristics section of the report defines and explains the market.
The market size section gives the market size ($b) covering both the historic growth of the market, and forecasting its development.
The forecasts are made after considering the major factors currently impacting the market. These include:
The forecasts are made after considering the major factors currently impacting the market. These include the technological advancements such as AI and automation, Russia-Ukraine war, trade tariffs (government-imposed import/export duties), elevated inflation and interest rates.
Market segmentations break down the market into sub markets.
The regional and country breakdowns section gives an analysis of the market in each geography and the size of the market by geography and compares their historic and forecast growth.
The competitive landscape chapter gives a description of the competitive nature of the market, market shares, and a description of the leading companies. Key financial deals which have shaped the market in recent years are identified.
The trends and strategies section analyses the shape of the market as it emerges from the crisis and suggests how companies can grow as the market recovers.
3) By Gene Therapy Medicinal Products: In Vivo Gene Therapy; Ex Vivo Gene Therapy; Viral Vector-Based Gene Therapy; Non-Viral Vector-Based Gene Therapy; Gene Editing Therapies
3. Advanced Therapy Medicinal Products Market Trends And Strategies
4. Advanced Therapy Medicinal Products Market - Macro Economic Scenario Including The Impact Of Interest Rates, Inflation, Geopolitics, Trade Wars and Tariffs, And Covid And Recovery On The Market
5. Global Advanced Therapy Medicinal Products Growth Analysis And Strategic Analysis Framework
5.1. Global Advanced Therapy Medicinal Products PESTEL Analysis (Political, Social, Technological, Environmental and Legal Factors, Drivers and Restraints)
5.2. Analysis Of End Use Industries
5.3. Global Advanced Therapy Medicinal Products Market Growth Rate Analysis
5.4. Global Advanced Therapy Medicinal Products Historic Market Size and Growth, 2019 - 2024, Value ($ Billion)
5.5. Global Advanced Therapy Medicinal Products Forecast Market Size and Growth, 2024 - 2029, 2034F, Value ($ Billion)
5.6. Global Advanced Therapy Medicinal Products Total Addressable Market (TAM)
6.1. Global Advanced Therapy Medicinal Products Market, Segmentation By Product, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
Somatic Cell Therapy Medicinal Products
Tissue Engineered Medicinal Products
Gene Therapy Medicinal Products
6.2. Global Advanced Therapy Medicinal Products Market, Segmentation By Technology, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
Gene Editing Technologies
Viral Vector Technology
Stem Cell Technology
Automation And Artificial Intelligence-Driven Processes
6.3. Global Advanced Therapy Medicinal Products Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
Muscular Dystrophies
Alzheimer's
Hemophilia
Cystic Fibrosis
Other Applications
6.4. Global Advanced Therapy Medicinal Products Market, Segmentation By Distribution Channel, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
Hospital Pharmacy
Retail Pharmacy
Online Pharmacy
6.5. Global Advanced Therapy Medicinal Products Market, Segmentation By End User, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
Hospitals
Specialty Clinics
Other End Users
6.6. Global Advanced Therapy Medicinal Products Market, Sub-Segmentation Of Somatic Cell Therapy Medicinal Products, By Type, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
Autologous Cell Therapy
Allogeneic Cell Therapy
Stem Cell Therapy
Dendritic Cell Therapy
Natural Killer Cell Therapy
6.7. Global Advanced Therapy Medicinal Products Market, Sub-Segmentation Of Tissue Engineered Medicinal Products, By Type, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
Autologous Tissue-Engineered Products
Allogeneic Tissue-Engineered Products
Scaffold-Based Tissue Engineering
Scaffold-Free Tissue Engineering
Skin Substitutes
6.8. Global Advanced Therapy Medicinal Products Market, Sub-Segmentation Of Gene Therapy Medicinal Products, By Type, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
In Vivo Gene Therapy
Ex Vivo Gene Therapy
Viral Vector-Based Gene Therapy
Non-Viral Vector-Based Gene Therapy
Gene Editing Therapies
7. Advanced Therapy Medicinal Products Market Regional And Country Analysis
7.1. Global Advanced Therapy Medicinal Products Market, Split By Region, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
7.2. Global Advanced Therapy Medicinal Products Market, Split By Country, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
Region Information, Market Information, Background Information, Government Initiatives, Regulations, Regulatory Bodies, Major Associations, Taxes Levied, Corporate Tax Structure, Investments, Major Companies
8.2. Asia-Pacific Advanced Therapy Medicinal Products Market, Segmentation By Product, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
8.3. Asia-Pacific Advanced Therapy Medicinal Products Market, Segmentation By Technology, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
8.4. Asia-Pacific Advanced Therapy Medicinal Products Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
9. China Advanced Therapy Medicinal Products Market
9.1. China Advanced Therapy Medicinal Products Market Overview
9.2. China Advanced Therapy Medicinal Products Market, Segmentation By Product, Historic and Forecast, 2019-2024, 2024-2029F, 2034F,$ Billion
9.3. China Advanced Therapy Medicinal Products Market, Segmentation By Technology, Historic and Forecast, 2019-2024, 2024-2029F, 2034F,$ Billion
9.4. China Advanced Therapy Medicinal Products Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F,$ Billion
10. India Advanced Therapy Medicinal Products Market
10.1. India Advanced Therapy Medicinal Products Market, Segmentation By Product, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
10.2. India Advanced Therapy Medicinal Products Market, Segmentation By Technology, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
10.3. India Advanced Therapy Medicinal Products Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
11. Japan Advanced Therapy Medicinal Products Market
11.1. Japan Advanced Therapy Medicinal Products Market Overview
11.2. Japan Advanced Therapy Medicinal Products Market, Segmentation By Product, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
11.3. Japan Advanced Therapy Medicinal Products Market, Segmentation By Technology, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
11.4. Japan Advanced Therapy Medicinal Products Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
12. Australia Advanced Therapy Medicinal Products Market
12.1. Australia Advanced Therapy Medicinal Products Market, Segmentation By Product, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
12.2. Australia Advanced Therapy Medicinal Products Market, Segmentation By Technology, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
12.3. Australia Advanced Therapy Medicinal Products Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
13. Indonesia Advanced Therapy Medicinal Products Market
13.1. Indonesia Advanced Therapy Medicinal Products Market, Segmentation By Product, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
13.2. Indonesia Advanced Therapy Medicinal Products Market, Segmentation By Technology, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
13.3. Indonesia Advanced Therapy Medicinal Products Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
14. South Korea Advanced Therapy Medicinal Products Market
14.1. South Korea Advanced Therapy Medicinal Products Market Overview
14.2. South Korea Advanced Therapy Medicinal Products Market, Segmentation By Product, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
14.3. South Korea Advanced Therapy Medicinal Products Market, Segmentation By Technology, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
14.4. South Korea Advanced Therapy Medicinal Products Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
15. Western Europe Advanced Therapy Medicinal Products Market
15.1. Western Europe Advanced Therapy Medicinal Products Market Overview
15.2. Western Europe Advanced Therapy Medicinal Products Market, Segmentation By Product, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
15.3. Western Europe Advanced Therapy Medicinal Products Market, Segmentation By Technology, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
15.4. Western Europe Advanced Therapy Medicinal Products Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
16. UK Advanced Therapy Medicinal Products Market
16.1. UK Advanced Therapy Medicinal Products Market, Segmentation By Product, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
16.2. UK Advanced Therapy Medicinal Products Market, Segmentation By Technology, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
16.3. UK Advanced Therapy Medicinal Products Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
20.1. Spain Advanced Therapy Medicinal Products Market, Segmentation By Product, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
20.2. Spain Advanced Therapy Medicinal Products Market, Segmentation By Technology, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
20.3. Spain Advanced Therapy Medicinal Products Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
21. Eastern Europe Advanced Therapy Medicinal Products Market
21.1. Eastern Europe Advanced Therapy Medicinal Products Market Overview
21.2. Eastern Europe Advanced Therapy Medicinal Products Market, Segmentation By Product, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
21.3. Eastern Europe Advanced Therapy Medicinal Products Market, Segmentation By Technology, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
21.4. Eastern Europe Advanced Therapy Medicinal Products Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
22. Russia Advanced Therapy Medicinal Products Market
22.1. Russia Advanced Therapy Medicinal Products Market, Segmentation By Product, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
22.2. Russia Advanced Therapy Medicinal Products Market, Segmentation By Technology, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
22.3. Russia Advanced Therapy Medicinal Products Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
23. North America Advanced Therapy Medicinal Products Market
23.1. North America Advanced Therapy Medicinal Products Market Overview
23.2. North America Advanced Therapy Medicinal Products Market, Segmentation By Product, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
23.3. North America Advanced Therapy Medicinal Products Market, Segmentation By Technology, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
23.4. North America Advanced Therapy Medicinal Products Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
24. USA Advanced Therapy Medicinal Products Market
24.1. USA Advanced Therapy Medicinal Products Market Overview
24.2. USA Advanced Therapy Medicinal Products Market, Segmentation By Product, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
24.3. USA Advanced Therapy Medicinal Products Market, Segmentation By Technology, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
24.4. USA Advanced Therapy Medicinal Products Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
25.2. Canada Advanced Therapy Medicinal Products Market, Segmentation By Product, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
25.3. Canada Advanced Therapy Medicinal Products Market, Segmentation By Technology, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
25.4. Canada Advanced Therapy Medicinal Products Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
26. South America Advanced Therapy Medicinal Products Market
26.1. South America Advanced Therapy Medicinal Products Market Overview
26.2. South America Advanced Therapy Medicinal Products Market, Segmentation By Product, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
26.3. South America Advanced Therapy Medicinal Products Market, Segmentation By Technology, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
26.4. South America Advanced Therapy Medicinal Products Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
27. Brazil Advanced Therapy Medicinal Products Market
27.1. Brazil Advanced Therapy Medicinal Products Market, Segmentation By Product, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
27.2. Brazil Advanced Therapy Medicinal Products Market, Segmentation By Technology, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
27.3. Brazil Advanced Therapy Medicinal Products Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
28. Middle East Advanced Therapy Medicinal Products Market
28.1. Middle East Advanced Therapy Medicinal Products Market Overview
28.2. Middle East Advanced Therapy Medicinal Products Market, Segmentation By Product, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
28.3. Middle East Advanced Therapy Medicinal Products Market, Segmentation By Technology, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
28.4. Middle East Advanced Therapy Medicinal Products Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
29. Africa Advanced Therapy Medicinal Products Market
29.1. Africa Advanced Therapy Medicinal Products Market Overview
29.2. Africa Advanced Therapy Medicinal Products Market, Segmentation By Product, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
29.3. Africa Advanced Therapy Medicinal Products Market, Segmentation By Technology, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
29.4. Africa Advanced Therapy Medicinal Products Market, Segmentation By Application, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
30. Advanced Therapy Medicinal Products Market Competitive Landscape And Company Profiles