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Protein Stability Analysis Global Market Report 2025
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Protein stability analysis refers to the evaluation of how stable a protein is under various conditions, such as temperature, pH, solvent composition, or over time. This analysis helps determine the ability of a protein to maintain its structure (folded conformation) and function without aggregating or degrading.

The primary product categories in protein stability analysis include reagents and assay kits, instruments, consumables and accessories, software, and other related products. Reagents and assay kits are chemical components and pre-assembled tools utilized in laboratories for detecting, quantifying, or analyzing biological or chemical reactions in research, diagnostics, or pharmaceutical development. The analysis is segmented by techniques such as chromatography, spectroscopy, surface plasma resonance imaging (SPRI), differential scanning calorimetry (DSC), differential scanning fluorimetry (DSF), and others. Key end users include pharmaceutical and biotechnology firms, contract research organizations, academic institutions, and research laboratories.

The protein stability analysis market research report is one of a series of new reports from The Business Research Company that provides protein stability analysis market statistics, including the protein stability analysis industry global market size, regional shares, competitors with the protein stability analysis market share, detailed protein stability analysis market segments, market trends, and opportunities, and any further data you may need to thrive in the protein stability analysis industry. These protein stability analysis market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.

The protein stability analysis market size has grown rapidly in recent years. It will grow from $2.32 billion in 2024 to $2.62 billion in 2025 at a compound annual growth rate (CAGR) of 12.7%. Growth during the historical period was supported by increasing development of biologics, heightened demand for biosimilars, enhanced focus on improving product shelf-life, regulatory emphasis on stability-related data, and the broadening of pharmaceutical research initiatives.

The protein stability analysis market size is expected to see rapid growth in the next few years. It will grow to $4.19 billion in 2029 at a compound annual growth rate (CAGR) of 12.5%. The projected growth is driven by the expansion of personalized medicine, greater funding in biopharmaceutical R&D, a rising need for high-throughput screening processes, increasing outsourcing activities to contract research organizations, and the push for advanced analytical technologies. Prominent trends expected in the forecast period include progress in high-throughput screening platforms, incorporation of artificial intelligence for predicting stability, emergence of microfluidic-based tools, increased automation in protein analysis workflows, and breakthroughs in computational modeling approaches.

The growing demand for biologics and biosimilars is expected to significantly drive the protein stability analysis market. Biologics are complex, large-molecule drugs derived from living organisms used in the treatment of various diseases, while biosimilars are highly similar, cost-effective alternatives to approved biologics that maintain clinical equivalence. This rising demand is fueled by patients and healthcare providers seeking more advanced, targeted therapies that deliver better treatment outcomes, increased accessibility, and reduced costs for chronic and complex conditions. Protein stability analysis plays a vital role in ensuring the safety, efficacy, and shelf life of biologics and biosimilars by monitoring their structural integrity and minimizing degradation. For example, according to Samsung Bioepis Co. Ltd., a South Korean biopharmaceutical company, as of 2024, the U.S. Food and Drug Administration (FDA) had approved 45 biosimilars, with 38 already launched in the U.S., reflecting robust market adoption and increased demand.

Companies in the protein stability analysis market are increasingly focusing on technological innovations such as the Veloci biopharma analyzer to enhance the precision, speed, and efficiency of protein characterization and quality assessment. The Veloci biopharma analyzer employs A-TEEM technology for rapid, label-free molecular fingerprinting tailored to life sciences applications, including protein stability testing and vaccine characterization. For instance, in March 2025, Horiba Advanced Techno Co. Ltd., a Japanese company specializing in analytical instruments, launched four new devices-among them, a biopharma analyzer featuring A-TEEM technology, a high-throughput Raman plate reader, and an advanced atomic force microscopy system. These tools are designed to improve molecular fingerprinting, enable real-time reaction monitoring, and facilitate multimodal material analysis, thereby advancing research in areas such as cell culture media, vaccines, and protein analysis.

In February 2022, Waters Corporation, a U.S.-based specialty measurement company, acquired the technology assets and intellectual property of Megadalton Solutions Inc. for an undisclosed sum. This strategic acquisition was intended to bolster Waters Corporation's capabilities and foster innovation in biopharmaceutical development, particularly in the fields of gene and cell therapy. Megadalton Solutions Inc., also based in the U.S., is known for its expertise in analyzing large proteins and protein complexes using charge detection mass spectrometry (CDMS).

Major players in the protein stability analysis market are Roche Diagnostics GmbH, Thermo Fisher Scientific Inc., Amgen Inc., General Electric Healthcare Inc., Agilent Technologies Inc., Charles River Laboratories International Inc., PerkinElmer Inc., Shimadzu Corporation, Sartorius AG, Waters Corporation, Bruker Corporation, HORIBA Ltd., Spectris plc, Unchained Labs Inc., NanoTemper Technologies GmbH, Enzo Life Sciences Inc., Jasco Inc., Neurelis Inc., Setaram Instrumentation SAS, and Luminex Corporation.

North America was the largest region in the protein stability analysis market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in protein stability analysis report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

The countries covered in the protein stability analysis market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

The protein stability analysis market consists of revenues earned by entities providing services such as thermal stability testing, structural analysis, and protein stability screening. The market value includes the value of related goods sold by the service provider or included within the service offering. The protein stability analysis market also includes sales of thermal shift assays, circular dichroism spectrometers, and differential scanning calorimetry instruments. Values in this market are 'factory gate' values, meaning the value of goods sold by manufacturers or creators of the products, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market also includes related services sold by the creators of the goods, such as installation, software updates, training, and maintenance support.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

Protein Stability Analysis Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.

This report focuses on protein stability analysis market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.

Reasons to Purchase

Where is the largest and fastest growing market for protein stability analysis ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward? The protein stability analysis market global report from the Business Research Company answers all these questions and many more.

The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.

The forecasts are made after considering the major factors currently impacting the market. These include the Russia-Ukraine war, rising inflation, higher interest rates, and the legacy of the COVID-19 pandemic.

Scope

Table of Contents

1. Executive Summary

2. Protein Stability Analysis Market Characteristics

3. Protein Stability Analysis Market Trends And Strategies

4. Protein Stability Analysis Market - Macro Economic Scenario Including The Impact Of Interest Rates, Inflation, Geopolitics, Trade Wars and Tariffs, And Covid And Recovery On The Market

5. Global Protein Stability Analysis Growth Analysis And Strategic Analysis Framework

6. Protein Stability Analysis Market Segmentation

7. Protein Stability Analysis Market Regional And Country Analysis

8. Asia-Pacific Protein Stability Analysis Market

9. China Protein Stability Analysis Market

10. India Protein Stability Analysis Market

11. Japan Protein Stability Analysis Market

12. Australia Protein Stability Analysis Market

13. Indonesia Protein Stability Analysis Market

14. South Korea Protein Stability Analysis Market

15. Western Europe Protein Stability Analysis Market

16. UK Protein Stability Analysis Market

17. Germany Protein Stability Analysis Market

18. France Protein Stability Analysis Market

19. Italy Protein Stability Analysis Market

20. Spain Protein Stability Analysis Market

21. Eastern Europe Protein Stability Analysis Market

22. Russia Protein Stability Analysis Market

23. North America Protein Stability Analysis Market

24. USA Protein Stability Analysis Market

25. Canada Protein Stability Analysis Market

26. South America Protein Stability Analysis Market

27. Brazil Protein Stability Analysis Market

28. Middle East Protein Stability Analysis Market

29. Africa Protein Stability Analysis Market

30. Protein Stability Analysis Market Competitive Landscape And Company Profiles

31. Protein Stability Analysis Market Other Major And Innovative Companies

32. Global Protein Stability Analysis Market Competitive Benchmarking And Dashboard

33. Key Mergers And Acquisitions In The Protein Stability Analysis Market

34. Recent Developments In The Protein Stability Analysis Market

35. Protein Stability Analysis Market High Potential Countries, Segments and Strategies

36. Appendix

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