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Gaucher¢¥s Disease Global Market Report 2025
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Gaucher's disease, a rare genetic disorder, disrupts the metabolism of a specific type of fat known as glucocerebroside. The disorder arises from the accumulation of a fatty substance called glucocerebroside within certain cells, particularly in the spleen, liver, bone marrow, and sometimes in the brain.

The primary categories of Gaucher's disease encompass Gaucher disease type 1, Gaucher disease type 2, Gaucher disease type 3, and others. Gaucher disease type 1, the most prevalent form, is distinguished by a deficiency of the enzyme glucocerebrosidase. The diverse diagnostic methods include physical examinations, blood tests, imaging tests, preconception screening, prenatal testing, and others. Treatment options involve enzyme replacement therapy and substrate reduction therapy, which can be administered through oral, parenteral, and various other routes by end users such as hospitals, specialty clinics, homecare, and others.

The Gaucher's disease market research report is one of a series of new reports from The Business Research Company that provides Gaucher's disease market statistics, including the Gaucher's disease industry global market size, regional shares, competitors with Gaucher's disease market share, detailed Gaucher's disease market segments, market trends and opportunities, and any further data you may need to thrive in the Gaucher's disease industry. This Gaucher's disease market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.

The gaucher's disease market size has grown strongly in recent years. It will grow from $1.68 billion in 2024 to $1.78 billion in 2025 at a compound annual growth rate (CAGR) of 5.9%. The growth in the historic period can be attributed to enzyme replacement therapy (ert) development, increasing disease awareness, genetic research and diagnosis, patient advocacy initiatives, government incentives for rare diseases.

The gaucher's disease market size is expected to see strong growth in the next few years. It will grow to $2.21 billion in 2029 at a compound annual growth rate (CAGR) of 5.6%. The growth in the forecast period can be attributed to next-generation therapies, global patient registry expansion, improvements in access to treatment, personalized medicine approaches, regulatory support for rare diseases. Major trends in the forecast period include technological innovations in treatment monitoring, international collaborations in research, oral therapeutics advancements, expanded newborn screening programs, global collaboration for patient access.

The increasing prevalence of genetic abnormalities is anticipated to drive the growth of the Gaucher's disease market in the coming years. Genetic abnormalities refer to changes or mutations in the DNA sequence of an individual's genes that can lead to abnormal features, functions, or characteristics. Gaucher's disease follows an autosomal recessive inheritance pattern, meaning that a person must inherit two copies of the mutated GBA gene, one from each parent, to develop the condition. Individuals with Gaucher's disease do not produce enough of a specific enzyme, resulting in the accumulation of fatty substances known as lipids in certain organs, such as the spleen and liver. For example, in 2023, the Cystic Fibrosis Foundation, a US-based non-profit organization, reported that the total population with cystic fibrosis without lung transplants was 31,171 in 2022 and rose to 31,752 in 2023. Thus, the increasing prevalence of genetic abnormalities is fueling the growth of the Gaucher's disease market.

The growth of the Gaucher's disease market is expected to be fueled by the rising number of clinical trials. Clinical trials, involving human participants, evaluate the safety and efficacy of new medical treatments, interventions, or drugs. Increased clinical trials in Gaucher's disease can lead to advancements in treatment, better disease understanding, improved diagnosis and screening, and the potential development of personalized medicine. According to Xtalks in May 2023, there are 452,604 registered clinical studies, with 64,838 actively seeking participants. This marks a substantial increase from the 365,000 registered trials in 2021, contributing significantly to the growth of the Gaucher's disease market.

Major companies in the Gaucher's disease market are adopting innovative technologies such as next-generation sequencing (NGS) to enhance patient care. NGS, a high-throughput sequencing technology, enables rapid and cost-effective DNA and RNA sequencing. For instance, Eurofins Genomics LLC launched a whole plasmid sequencing service utilizing advanced Gen3 NGS technology, offering same-day results with up to 99% single-base accuracy. This service, accommodating DNA constructs from 2.5 to 300 kb, combines the accuracy and quick turnaround of Sanger sequencing with NGS's comprehensive analysis capabilities, providing a cost-effective and time-efficient solution for genetic analysis.

Key companies in the Gaucher disease market are concentrating on developing innovative solutions such as AAV gene therapy, aimed at providing a groundbreaking, one-time treatment for Gaucher disease Type 1. Adeno-associated virus (AAV) gene therapy utilizes AAV vectors to deliver therapeutic genes to cells, thereby correcting disease-causing mutations. For example, in January 2022, Freeline Therapeutics Holdings plc, a UK-based biotechnology firm, announced that the US FDA approved FLT201 for Gaucher disease Type 1. FLT201 employs an advanced AAVS3 capsid paired with a liver-specific promoter to deliver a novel glucocerebrosidase variant (GCasevar85). This FDA-cleared IND represents the first AAV-mediated gene therapy to enter clinical trials for Gaucher disease Type 1, underscoring its potential to provide a new therapeutic option for patients.

Major companies operating in the gaucher's disease market report are Pfizer Inc., Johnson & Johnson, Merck and Co. Inc., Novartis AG, Sanofi S.A., Abbott Laboratories, GlaxoSmithKline PLC, Takeda Pharmaceutical Company Limited, Moderna Inc., Teva Pharmaceutical Industries Ltd., Boehringer Ingelheim International GmbH, BioMarin Pharmaceutical Inc., CHIESI Farmaceutici SPA, IntraBio Inc., REGENXBIO Inc., JCR Pharmaceuticals Co. Ltd., Ultragenyx Pharmaceutical Inc., Amicus Therapeutics Inc., Pharming Group N.V., Idorsia Pharmaceuticals Ltd., Centogene N.V., Protalix BioTherapeutics, AVROBIO Inc., Resverlogix Corp., GenSight Biologics S.A., ISU Abxis Co. Ltd., SIRION BIOTECH GmbH, Greenovation Biotech GmbH, Orphazyme A/S

North America was the largest region in the Gaucher's disease market in 2024. Europe is expected to be the fastest growing region in the forecast period. The regions covered in the gaucher's disease market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa

The countries covered in the gaucher's disease market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain

The gaucher's disease market includes revenues earned by entities by providing services such as genetic counseling, patient education and support, research and clinical trials, and pain management services. The market value includes the value of related goods sold by the service provider or included within the service offering. Only goods and services traded between entities or sold to end consumers are included. The gaucher's disease market consists of sales of bone health supplements, medical equipment, and diagnostic testing kits. Values in this market are 'factory gate' values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

Gaucher's Disease Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.

This report focuses on gaucher's disease market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.

Reasons to Purchase

Where is the largest and fastest growing market for gaucher's disease ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward? The gaucher's disease market global report from the Business Research Company answers all these questions and many more.

The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.

The forecasts are made after considering the major factors currently impacting the market. These include the Russia-Ukraine war, rising inflation, higher interest rates, and the legacy of the COVID-19 pandemic.

Scope

Table of Contents

1. Executive Summary

2. Gaucher's Disease Market Characteristics

3. Gaucher's Disease Market Trends And Strategies

4. Gaucher's Disease Market - Macro Economic Scenario Including The Impact Of Interest Rates, Inflation, Geopolitics, Covid And Recovery On The Market

5. Global Gaucher's Disease Growth Analysis And Strategic Analysis Framework

6. Gaucher's Disease Market Segmentation

7. Gaucher's Disease Market Regional And Country Analysis

8. Asia-Pacific Gaucher's Disease Market

9. China Gaucher's Disease Market

10. India Gaucher's Disease Market

11. Japan Gaucher's Disease Market

12. Australia Gaucher's Disease Market

13. Indonesia Gaucher's Disease Market

14. South Korea Gaucher's Disease Market

15. Western Europe Gaucher's Disease Market

16. UK Gaucher's Disease Market

17. Germany Gaucher's Disease Market

18. France Gaucher's Disease Market

19. Italy Gaucher's Disease Market

20. Spain Gaucher's Disease Market

21. Eastern Europe Gaucher's Disease Market

22. Russia Gaucher's Disease Market

23. North America Gaucher's Disease Market

24. USA Gaucher's Disease Market

25. Canada Gaucher's Disease Market

26. South America Gaucher's Disease Market

27. Brazil Gaucher's Disease Market

28. Middle East Gaucher's Disease Market

29. Africa Gaucher's Disease Market

30. Gaucher's Disease Market Competitive Landscape And Company Profiles

31. Gaucher's Disease Market Other Major And Innovative Companies

32. Global Gaucher's Disease Market Competitive Benchmarking And Dashboard

33. Key Mergers And Acquisitions In The Gaucher's Disease Market

34. Recent Developments In The Gaucher's Disease Market

35. Gaucher's Disease Market High Potential Countries, Segments and Strategies

36. Appendix

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