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CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and Cas (CRISPR-associated) genes form part of a bacterial immune system that protects against viruses and foreign genetic elements. CRISPR refers to sequences of deoxyribonucleic acid (DNA) that contain short, repetitive segments, which bacteria use to store snippets of viral DNA after an infection. If the bacteria encounter the same virus again, they can recognize it based on these stored sequences. Cas genes encode proteins (like Cas9) that act as molecular scissors. These proteins can cut DNA at specific sites guided by RNA molecules (gRNA), which are transcribed from the CRISPR sequences. This mechanism allows precise gene editing and has revolutionized genetic research, enabling scientists to alter DNA in plants, animals and humans with high accuracy.
The CRISPR and Cas gene market consists of sales, by entities (organizations, sole traders and partnerships), of gene-editing tools and technologies used for precise DNA modifications.
The global CRISPR and CAS gene market was valued at $1,297.36 million in 2018 which grew till 2023 at a compound annual growth rate (CAGR) of more than 20.0%.
Growing Interest In Personalized Medicine
Growing interest in personalized medicine propelled the growth of the CRISPR and CAS gene market. Personalized medicine, also known as precision medicine or individualized medicine, is an approach to medical care that aims to tailor treatments and interventions to the specific characteristics of each patient. Personalized medicine drives demand for precise genetic therapies, focusing on treatments tailored to an individual's genetic profile. CRISPR technology enables targeted gene editing to address these variations, leading to increased investment in CRISPR-based therapies. This has accelerated its adoption for treating genetic disorders, cancer and other conditions in healthcare. For instance, in October 2022, according to the Personalized Medicine Coalition, a US-based organization that represents scientists, patients and providers, promoting the understanding and adoption of personalized medicine to benefit patients and the healthcare system, more than 75,000 genetic testing products and 300 personalized medicines were present on the market for people with multiple types of cancers, genetic rare diseases and a range of chronic and infectious diseases. Additionally, personalized medicines accounted for 34% of new drug approvals by the US Food and Drug Administration in 2022 and have accounted for at least 25% of approvals in each of the previous eight years. Therefore, growing interest in personalized medicine supported the growth of the CRISPR and CAS gene market during the historic period.
Advanced Gene Editing Tools To Revolutionize Personalized Medicine Through Precise Genetic Modifications
Major companies in the CRISPR and Cas gene market are focusing on developing advanced gene editing tools to enhance personalized medicine through precise genetic modifications. These tools enable targeted treatments tailored to an individual's genetic profile, addressing conditions like genetic disorders, cancer and rare diseases. By modifying specific genes responsible for disease progression, CRISPR technologies offer more effective therapies, improving patient outcomes and minimizing risks compared to traditional treatments, marking a significant advancement in precision medicine. For example, in May 2024, Profluent, a US-based AI-first protein design company, released the sequence of OpenCRISPR-1, a novel Cas9 gene editor with improved off-target editing created through Profluent's artificial intelligence (AI), using large language model trained on a database of 5.1 million Cas9-like proteins. This open-source project has the potential to revolutionize CRISPR treatment options by leveraging AI to develop new gene-editing reagents, marking a significant step forward in precision medicine.
The global CRISPR and Cas gene market is highly concentrated, with large players operating in the market. The top ten competitors in the market made up to 70.11% of the total market in 2023.
CRISPR And Cas Gene Global Market Opportunities And Strategies To 2033 from The Business Research Company provides the strategists; marketers and senior management with the critical information they need to assess the global CRISPR and Cas gene market as it emerges from the COVID-19 shut down.
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Where is the largest and fastest-growing market for CRISPR and Cas gene? How does the market relate to the overall economy; demography and other similar markets? What forces will shape the market going forward? The CRISPR and Cas gene market global report from The Business Research Company answers all these questions and many more.
The report covers market characteristics; size and growth; segmentation; regional and country breakdowns; competitive landscape; market shares; trends and strategies for this market. It traces the market's history and forecasts market growth by geography. It places the market within the context of the wider CRISPR and Cas gene market; and compares it with other markets.
The report covers the following chapters
Introduction and Market Characteristics- Brief introduction to the segmentations covered in the market, definitions and explanations about the segment by type, by application, by product type, by end use and by service type.
Key Trends- Highlights the major trends shaping the global market. This section also highlights likely future developments in the market.
Macro-Economic Scenario- The report provides an analysis of the impact of the COVID-19 pandemic, impact of the Russia-Ukraine war and impact of rising inflation on global and regional markets, providing strategic insights for businesses in the CRISPR and Cas gene market.
Global Market Size And Growth- Global historic (2018-2023) and forecast (2023-2028, 2033F) market values and drivers and restraints that support and control the growth of the market in the historic and forecast periods.
Regional And Country Analysis- Historic (2018-2023) and forecast (2023-2028, 2033F) market values and growth and market share comparison by region and country.
Market Segmentation- Contains the market values (2018-2023) (2023-2028, 2033F) and analysis for each segment by type, by application, by product type, by end use and by service type in the market. Historic (2018-2023) and forecast (2023-2028) and (2028-2033) market values and growth and market share comparison by region market.
Regional Market Size and Growth- Regional market size (2023), historic (2018-2023) and forecast (2023-2028, 2033F) market values and growth and market share comparison of countries within the region. This report includes information on all the regions Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa and major countries within each region.
Competitive Landscape- Details on the competitive landscape of the market, estimated market shares and company profiles of the leading players.
Other Major And Innovative Companies- Details on the company profiles of other major and innovative companies in the market.
Competitive Dashboard- Briefs on competitive dashboard of major players.
Competitive Benchmarking- Briefs on the financials comparison between major players in the market.
Market Opportunities And Strategies- Describes market opportunities and strategies based on findings of the research, with information on growth opportunities across countries, segments and strategies to be followed in those markets.
Conclusions And Recommendations- This section includes recommendations for CRISPR and Cas gene providers in terms of product/service offerings geographic expansion, marketing strategies and target groups.
Appendix- This section includes details on the NAICS codes covered, abbreviations and currencies codes used in this report.
Markets Covered:
1) By Type: Products; Services
2) By Application: Genome Engineering; Disease Model Studies; Functional Genomics; Epigenetics; Other Applications
3) By Product Type: Kits And Enzymes; Libraries; Design Tool; Antibodies; Other Products
4) By End Use: Biotechnology And Pharmaceutical Companies; Academics And Government Research Institutes; Contract Research Organizations (CROs)
5) By Service Type: Cell Line Engineering, Grna Design, Microbial Gene Editing; DNA Synthesis