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Thermo Fisher Scientific Inc.
Merck KGaA(Sigma-Aldrich)
OriGene Technologies, Inc.
New England Biolabs
Cellecta, Inc.
Agilent Technologies
Applied StemCell, Inc.
Synthego
Genscript
Mirus Bio LLC
Integrated DNA Technologies, Inc.
Mammoth Biosciences, Inc.
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Crispr And Cas Gene Market is estimated to be valued at USD 2.32 Bn in 2025 and is expected to reach USD 9.77 Bn by 2032, growing at a compound annual growth rate (CAGR) of 22.8% from 2025 to 2032.
Report Coverage
Report Details
Base Year:
2024
Market Size in 2025:
USD 2.32 Bn
Historical Data for:
2020 To 2024
Forecast Period:
2025 To 2032
Forecast Period 2025 to 2032 CAGR:
22.80%
2032 Value Projection:
USD 9.77 Bn
Clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 is a unique technology that enables the geneticists and medical researchers to edit parts of the genome by removing, adding or altering sections of the deoxyribonucleic acids (DNA) sequence. The CRISPR-Cas9 system consists of two key molecules that introduce a mutation into the DNA. The first component is an enzyme, which is called as Cas9. This acts as a pair of 'molecular scissors' that can cut the two strands of DNA at a specific location in the genome so that bits of DNA can then be added or removed. The second component is called guide RNA (gRNA). This consists of a small piece of pre-designed RNA sequence (about 20 bases long) located within a longer RNA scaffold. The scaffold part binds to DNA and the pre-designed sequence 'guides' Cas9 to the right part of the genome. This makes sure that the Cas9 enzyme cuts at the right point in the genome.
Market Dynamics
Key players are developing various treatment options, such as CRISPR and CAS genes, for genetic diseases. For instance, in 2016, the U.S.-based company, Addgene, developed the KamiCas9, a version of CRISPR-Cas9 that includes a 'self-inactivating' KamiCas9 system for the editing of central nervous system (CNS) disease genes for the treatment of Huntington's disease.
CRISPR technology is widely used to develop therapeutics for diseases such as diabetes, cancer, etc. Hence, the increasing prevalence of such diseases is expected to drive the market growth over the forecast period. According to The International Diabetes Federation, in 2019, approximately 463 million adults (20-79 years of age) were living with diabetes; by 2045, this will increase to 700 million worldwide. Moreover, one in five of the people who are above 65 years old have diabetes.
Furthermore, according to data findings by the World Health Organization (WHO), in February 2018, cancer was the second-leading cause of death globally, and around 18.1 million new cases and 9.6 million deaths were registered due to cancer. According to the same source, around 70% of deaths from cancer occurred in low and middle income countries, and around one in six deaths across the globe were caused by cancer.
Key features of the study:
This report provides an in-depth analysis of global CRISPR and CAS gene market, provides market size (US$ Billion), and compound annual growth rate (CAGR %) for the forecast period 2025-2032, considering 2024 as the base year
It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrix for this market
This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, regional outlook, and competitive strategies adopted by the leading players
It profiles leading players in the global CRISPR and CAS gene market based on the following parameters - company overview, financial performance, product portfolio, geographical presence, distribution strategies, key developments and strategies, and future plans
Key companies covered as a part of this study include Thermo Fisher Scientific Inc., Merck KGaA (Sigma-Aldrich), OriGene Technologies, Inc., New England Biolabs, Cellecta, Inc., Agilent Technologies, Inc., Applied StemCell, Inc., Synthego, Genscript, Mirus Bio LLC, Integrated DNA Technologies, Inc., and Mammoth Biosciences, Inc.
Insights from this report would allow marketers and the management authorities of the companies to make informed decision regarding their future product launch, technology up-gradation, market expansion, and marketing tactics
The global CRISPR and CAS gene market report caters to various stakeholders in this industry including investors, suppliers, manufacturers, distributors, new entrants, and financial analysts
Stakeholders would have ease in decision making through various strategy matrices used in analyzing the CRISPR and CAS gene market
Detailed Segmentation:
Global CRISPR and CAS Gene Market, By Product Type:
Vector-based CAS
DNA-free CAS
Others
Global CRISPR and CAS Gene Market, By Application:
Genome Engineering
Disease Models
Functional Genomics
Knockdown/Activation
Others
Global CRISPR and CAS Gene Market, By End User:
Biotechnology and Pharmaceutical Companies
Academic & Government Research Institutes
Contract Research Organizations
Global CRISPR and CAS Gene Market, By Region:
North America
By Country:
U.S.
Canada
Latin America
By Country:
Brazil
Mexico
Argentina
Rest of Latin America
Europe
By Country:
U.K.
Germany
Italy
Spain
France
Russia
Rest of Europe
Asia Pacific
By Country:
Australia
India
China
Japan
ASEAN
South Korea
Rest of Asia Pacific
Middle East
By Country:
GCC
Israel
Rest of Middle East
Africa
By Country/Region:
South Africa
Central Africa
North Africa
Company Profiles
Thermo Fisher Scientific Inc.
Merck KGaA (Sigma-Aldrich)
OriGene Technologies, Inc.
New England Biolabs
Cellecta, Inc.
Agilent Technologies, Inc.
Applied StemCell, Inc.
Synthego
Genscript
Mirus Bio LLC
Integrated DNA Technologies, Inc.
Mammoth Biosciences, Inc.
Table of Contents
1. Research Objectives and Assumptions
Research Objectives
Assumptions
Abbreviations
2. Market Purview
Report Description
Market Definition and Scope
Executive Summary
Market Snippet, By Product Type
Market Snippet, By Application
Market Snippet, By End User
Market Snippet, By Region
Coherent Opportunity Map (COM)
3. Market Dynamics, Regulations, and Trends Analysis
Market Dynamics
Drivers
Restraints
Opportunities
Recent Trends
Merger, Acquisition, and Collaborations
Regulatory Scenario
Key Developments
PEST Analysis
PORTER's Analysis
4. Global Crispr And Cas Gene Market, By Product Type, 2020 - 2032, (US$ Bn)
Introduction
Market Share Analysis, 2025 and 2032 (%)
Y-o-Y Growth Analysis, 2021 - 2032
Segment Trends
Vector-based Cas
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020 - 2032, (US$ Bn)
Segment Trends
DNA-free Cas
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020 - 2032, (US$ Bn)
Segment Trends
Others
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020 - 2032, (US$ Bn)
Segment Trends
5. Global Crispr And Cas Gene Market, By Application, 2020 - 2032, (US$ Bn)
Introduction
Market Share Analysis, 2025 and 2032 (%)
Y-o-Y Growth Analysis, 2021 - 2032
Segment Trends
Genome Engineering
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020 - 2032, (US$ Bn)
Segment Trends
Disease Models
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020 - 2032, (US$ Bn)
Segment Trends
Functional Genomics
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020 - 2032, (US$ Bn)
Segment Trends
Knockdown/Activation
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020 - 2032, (US$ Bn)
Segment Trends
Others
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020 - 2032, (US$ Bn)
Segment Trends
6. Global Crispr And Cas Gene Market, By End User, 2020 - 2032, (US$ Bn)
Introduction
Market Share Analysis, 2025 and 2032 (%)
Y-o-Y Growth Analysis, 2021 - 2032
Segment Trends
Biotechnology and Pharmaceutical Companies
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020 - 2032, (US$ Bn)
Academic & Government Research Institutes
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020 - 2032, (US$ Bn)
Contract Research Organizations
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020 - 2032, (US$ Bn)
7. Global Crispr And Cas Gene Market, By Region, 2020 - 2032, (US$ Bn)
Introduction
Market Share Analysis, 2025 and 2032 (%)
Y-o-Y Growth Analysis, 2021-2032
Segment Trends
North America
Market Size and Forecast, Y-o-Y Growth, By Product Type, 2020 - 2032, (US$ Bn)
Market Size and Forecast, Y-o-Y Growth, By Application, 2020 - 2032, (US$ Bn)
Market Size and Forecast, Y-o-Y Growth, By End User, 2020 - 2032, (US$ Bn)
Market Size and Forecast, By Country, Y-o-Y Growth, By Country, 2020 -2032, (US$ Bn)
U.S.
Canada
Europe
Market Size and Forecast, Y-o-Y Growth, By Product Type, 2020 - 2032, (US$ Bn)
Market Size and Forecast, Y-o-Y Growth, By Application, 2020 - 2032, (US$ Bn)
Market Size and Forecast, Y-o-Y Growth, By End User, 2020 - 2032, (US$ Bn)
Market Size and Forecast, By Country, Y-o-Y Growth, By Country, 2020 -2032, (US$ Bn)
U.K.
Germany
Italy
France
Spain
Russia
Rest of Europe
Asia Pacific
Market Size and Forecast, Y-o-Y Growth and By Product Type, 2020 -2032, (US$ Bn)
Market Size and Forecast, Y-o-Y Growth and By Application, 2020 - 2032, (US$ Bn)
Market Size and Forecast, Y-o-Y Growth and By End User, 2020 - 2032, (US$ Bn)
Market Size and Forecast, By Country, Y-o-Y Growth and By Country, 2020 - 2032, (US$ Bn)
China
India
Japan
ASEAN
Australia
South Korea
Rest of Asia Pacific
Latin America
Market Size and Forecast, Y-o-Y Growth, By Product Type, 2020 - 2032, (US$ Bn)
Market Size and Forecast, Y-o-Y Growth, By Application, 2020 - 2032, (US$ Bn)
Market Size and Forecast, Y-o-Y Growth, By End User, 2020 - 2032, (US$ Bn)
Market Size and Forecast, By Country, Y-o-Y Growth, By Country, 2020 -2032, (US$ Bn)
Brazil
Mexico
Argentina
Rest of Latin America
Middle East
Market Size and Forecast, Y-o-Y Growth, By Product Type, 2020 - 2032, (US$ Bn)
Market Size and Forecast, Y-o-Y Growth, By Application, 2020 - 2032, (US$ Bn)
Market Size and Forecast, Y-o-Y Growth, By End User, 2020 - 2032, (US$ Bn)
Market Size and Forecast, By Country, Y-o-Y Growth, By Country, 2020 - 2032, (US$ Bn)
GCC
Israel
Rest of Middle East
Africa
Market Size and Forecast, Y-o-Y Growth, By Product Type, 2020 - 2032, (US$ Bn)
Market Size and Forecast, Y-o-Y Growth, By Application, 2020 - 2032, (US$ Bn)
Market Size and Forecast, Y-o-Y Growth, By End User, 2020 - 2032, (US$ Bn)
Market Size and Forecast, By Country, Y-o-Y Growth, By Country/Region, 2020 -2032, (US$ Bn)