T-cell Therapy Market Size, Share, Growth Analysis, By Modality, By Type(CAR T-cell Therapy, T Cell Receptor -based, Tumor Infiltrating Lymphocytes -based), By Indication, By End User, By Region - Industry Forecast 2024-2031
Global T-Cell Therapy Market size was valued at USD 2.83 billion in 2022 and is poised to grow from USD 3.83 billion in 2023 to USD 43.0 billion by 2031, growing at a CAGR of 35.3% during the forecast period (2024-2031).
Cancer remains one of the leading causes of mortality worldwide, with projections indicating an addition of 27.5 million cases by 2040, imposing heavy financial, emotional, and physical strains on individuals and healthcare systems alike. While existing treatment options can slow disease progression, achieving long-lasting remission remains a challenge. In response, immunotherapies, particularly T-cell therapies such as CAR-T, TCR, and TIL therapies, are gaining traction for their ability to effectively target and eliminate tumor cells with fewer side effects. This innovative approach harnesses the human immune system's power, positioning T-cell therapy as a transformative solution in cancer treatment. As the development of these cell therapies continues to accelerate, this emerging sector is poised to become one of the most lucrative markets in the biopharmaceutical industry.
Top-down and bottom-up approaches were used to estimate and validate the size of the Global T-Cell Therapy market and to estimate the size of various other dependent submarkets. The research methodology used to estimate the market size includes the following details: The key players in the market were identified through secondary research, and their market shares in the respective regions were determined through primary and secondary research. This entire procedure includes the study of the annual and financial reports of the top market players and extensive interviews for key insights from industry leaders such as CEOs, VPs, directors, and marketing executives. All percentage shares split, and breakdowns were determined using secondary sources and verified through Primary sources. All possible parameters that affect the markets covered in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data.
Global T-Cell Therapy Market Segmental Analysis
Global T-Cell Therapy Market is segmented by therapy type, modality, indication, end-user and region. Based on therapy type, the market is segmented into CAR T-cell therapy, tumor-infiltrating lymphocytes (TIL) therapy and t cell receptor (TCR)-based therapy. Based on modality, the market is segmented into research use and clinical use. Based on indication, the market is segmented into hematologic malignancies, solid tumors, infectious diseases and autoimmune diseases. Based on end-user, the market is segmented into hospitals, cancer treatment centers and research institutes. Based on region, the market is segmented into North America, Europe, Asia Pacific, Latin America and Middle East & Africa.
Driver of the Global T-Cell Therapy Market
The Global T-Cell Therapy market is being significantly driven by the recent FDA approvals of Yescarta, Kymriah, and Tecartus, prompting numerous companies to pivot from developing traditional protein and small-molecule therapeutics to focus on adoptive therapies as their core business strategy. This shift has led to a remarkable increase in the T-cell therapy market, bolstered by strategic investments from both public and private sectors. The burgeoning gene therapy landscape plays a crucial role, as these advancements enhance the efficacy of CAR-T therapies. Additionally, the integration of T-cell approaches in cancer immunotherapy, combined with substantial funding dedicated to CAR T-cell research, is expected to propel the market, particularly with an expanding clinical trial environment for various hematologic cancers.
Restraints in the Global T-Cell Therapy Market
The T-cell therapy market faces significant constraints primarily due to the limited effectiveness of CAR-T therapies in treating solid tumors, compounded by safety concerns arising from the highly immunosuppressive tumor microenvironment. These challenges hinder market expansion, prompting industry stakeholders to explore innovative strategies to overcome these obstacles. Efforts are being made to enhance the applicability of CAR-T treatments in solid tumors, which may subsequently widen their therapeutic impact and improve patient outcomes. As the sector evolves, addressing these limitations will be crucial for tapping into the full potential of T-cell therapies in various oncological applications.
Market Trends of the Global T-Cell Therapy Market
The Global T-Cell Therapy market is witnessing a notable trend towards the application of CAR T-cell therapies in the treatment of solid tumors, particularly in challenging cases such as diffuse midline glioma, a rare and aggressive pediatric cancer. Research highlights the potential of CAR T-cell treatment to significantly improve patient outcomes, with successful trials showing extended tumor eradication in animal models despite facing toxicity challenges. Intracerebroventricular (ICV) delivery methods are emerging as a safer, more efficient alternative to systemic administration, marking a pivotal shift in therapeutic strategies. This evolving landscape is expected to drive substantial growth in the T-Cell Therapy market, attracting investments and innovations tailored for solid tumor applications.
Table of Contents
Introduction
Objectives of the Study
Scope of the Report
Definitions
Research Methodology
Information Procurement
Secondary & Primary Data Methods
Market Size Estimation
Market Assumptions & Limitations
Executive Summary
Global Market Outlook
Supply & Demand Trend Analysis
Segmental Opportunity Analysis
Market Dynamics & Outlook
Market Overview
Market Size
Market Dynamics
Drivers & Opportunities
Restraints & Challenges
Porters Analysis
Competitive rivalry
Threat of substitute
Bargaining power of buyers
Threat of new entrants
Bargaining power of suppliers
Key Market Insights
Key Success Factors
Degree of Competition
Top Investment Pockets
Market Ecosystem
Market Attractiveness Index, 2023
PESTEL Analysis
Macro-Economic Indicators
Value Chain Analysis
Pricing Analysis
Regulatory Landscape
Patent Analysis
Case Studies
Global T-Cell Therapy Market Size by Therapy Type & CAGR (2024-2031)
Market Overview
CAR T-Cell Therapy
Tumor-Infiltrating Lymphocytes (TIL) Therapy
T Cell Receptor (TCR)-Based Therapy
Global T-Cell Therapy Market Size by Modality & CAGR (2024-2031)
Market Overview
Research Use
Clinical Use
Global T-Cell Therapy Market Size by Indication & CAGR (2024-2031)
Market Overview
Hematologic Malignancies
Lymphoma
Leukemia
Multiple Myeloma
Solid Tumors
Melanoma
Lung Cancer
Colorectal Cancer
Breast Cancer
Infectious Diseases
COVID-19
HIV
Autoimmune Diseases
Rheumatoid Arthritis
Multiple Sclerosis
Global T-Cell Therapy Market Size by End-User & CAGR (2024-2031)
Market Overview
Hospitals
Cancer Treatment Centers
Research Institutes
Global T-Cell Therapy Market Size & CAGR (2024-2031)
North America (Therapy Type, Modality, Indication, End-User)
USA
Canada
Europe (Therapy Type, Modality, Indication, End-User)
Germany
Spain
France
UK
Italy
Rest of Europe
Asia Pacific (Therapy Type, Modality, Indication, End-User)
China
India
Japan
South Korea
Rest of Asia-Pacific
Latin America (Therapy Type, Modality, Indication, End-User)
Brazil
Rest of Latin America
Middle East & Africa (Therapy Type, Modality, Indication, End-User)