지질 나노입자 제조 시장 : 전달 분자 유형별, 사업 규모별, 기업 규모별, 주요 지역별 - 업계 동향과 세계 예측(-2035년)
Lipid Nanoparticle Manufacturing Market by Type of Lipid Nanoparticle, Type of Molecule Delivered, Company Size, Target Therapeutic Area, Type of End-user and Key Geographical Regions : Industry Trends and Global Forecasts, Till 2035
상품코드:1648559
리서치사:Roots Analysis
발행일:2025년 01월
페이지 정보:영문 290 Pages
라이선스 & 가격 (부가세 별도)
한글목차
세계의 지질 나노입자 제조 시장 규모는 2035년까지의 예측 기간 중 18.86%의 CAGR로 확대하며, 현재 3억 7,000만 달러에서 2035년까지 25억 3,000만 달러로 성장할 것으로 예측됩니다.
지난 수십년간 제약 산업은 괄목할 만한 성장을 이루었습니다. 이는 시판되었거나 여러 단계의 개발 단계에 있는 신약 후보물질의 파이프라인이 지속적으로 증가하고 있는 것으로도 알 수 있습니다. 그러나 약물의 낮은 용해도/투과성은 특정 약리학적 제품과 관련된 주요 관심사 중 하나입니다. 따라서 제약 분야 기업은 약리학적 제제의 물리화학적 특성 및 약물과 유사한 거동을 개선하고 강화하는 방법을 적극적으로 모색하고 있습니다. 다른 대안 중 지질 나노입자(LNP)의 사용은 많은 의약품 개발자의 관심을 끌고 있습니다. 이는 LNP가 구조와 기능면에서 매우 다양하고 난수용성 약물의 용해도와 생체 이용률을 향상시킬 수 있는 능력을 가지고 있기 때문입니다.
일상 업무와 관련된 기술적 문제를 고려하여 점점 더 많은 제약회사들이 LNP 제조를 전문업체에 위탁하고 있으며, LNP 제조를 위해 위탁 생산업체를 이용하는 것은(서비스 프로바이더가 제공하는) 신기술에 대한 접근성, 더 큰 생산 능력, 더 큰 운영 유연성 등 많은 이점이 있습니다. 그 결과, 많은 기업이 전략적 제휴를 맺고 각자의 서비스 포트폴리오와 LNP 제조 능력을 확장하여 이 분야에서의 입지를 강화하기 위해 적극적으로 노력하고 있으며, LNP를 사용하여 약물과 같은 특성을 개선할 수 있는 이점을 고려할 때, 고품질 LNP 나노입자에 대한 수요가 증가할 것입니다.에 대한 수요는 향후 수년간 특수 수탁제조 시장에서 상당한 성장을 가속할 것으로 예상됩니다.
복수의 서비스 프로바이더가, 다양한 규모의 사업과 다양한 유형의 분자 인캡슐레이션에 대응하는 지질 나노입자 수탁제조에 필요한 역량을 보유하고 있습니다. 현재 약 35개의 지질 나노입자 기술이 LNP 기반 치료제를 제조하기 위해 전 세계 기업에 의해 제공되고 있습니다.
현재 전 세계에서 약 60개 기업이 다양한 치료 목적으로 다른 유형의 지질 개발 및 생산을 지원하는 수탁제조 서비스를 제공한다고 주장하고 있습니다. 지질 나노입자에 대한 수요 증가에 대응하기 위해 서비스 제공 업체는 기존 역량을 지속적으로 확장하고 진화하는 업계 벤치마크를 준수하기 위해 노력하고 있습니다. 경쟁 우위를 확보하기 위해 업계 이해관계자들은 각자의 포트폴리오를 강화하기 위해 새로운 LNP 제조 기술을 적극적으로 발전시키고 혁신하고 있습니다.
세계의 지질 나노입자 제조 시장에 대해 조사했으며, 시장의 개요와 전달 분자 유형별, 사업 규모별, 기업 규모별, 주요 지역별 동향 및 시장에 참여하는 기업의 개요 등을 제공하고 있습니다.
목차
제1장 서문
제2장 조사 방법
제3장 경제 및 기타 프로젝트 특유의 고려 사항
제4장 개요
제5장 서론
제6장 지질 나노입자 : 서비스 프로바이더의 상황
챕터 개요
지질 나노입자 제조 : 서비스 프로바이더 리스트
제7장 지질 나노입자 : 기술 상황
제8장 기타 지질 : 서비스 프로바이더의 상황
제9장 기업 경쟁력 분석
챕터 개요
전제와 주요 파라미터
조사 방법
지질 나노입자 제조 서비스 프로바이더 : 기업 경쟁력 분석
제10장 기술 경쟁력 분석
제11장 기업 개요 : 지질 나노입자 서비스 프로바이더
챕터 개요
Curia
Emergent BioSolutions
EUROAPI
Evonik
Ardena
BIOVECTRA
Company Overview
Precision NanoSystems
제12장 기업 개요 : 지질 나노입자 기술개발 기업
챕터 개요
Ascendia Pharmaceuticals
leon-nanodrugs
Pantherna Therapeutics
TLC Biosciences
Acuitas Therapeutics
Integrated Nanotherapeutics
Matinas BioPharma
제13장 기업 개요 : 기타 지질 서비스 프로바이더
챕터 개요
Avanti Polar Lipids
Corden Pharma
Fujifilm
Merck
FormuMax Scientific
Creative Biolabs
Fresenius Kabi
제14장 파트너십과 협업
제15장 파트너 후보의 분석
제16장 제조 대 구입 의사결정 프레임워크
제17장 용량 분석
제18장 시장에 대한 영향 분석 : 촉진요인, 억제요인, 기회, 과제
제19장 세계의 지질 나노입자 제조 시장
제20장 지질 나노입자 제조 시장(전달 분자 유형별)
제21장 지질 나노입자 제조 시장(사업 규모별)
제22장 지질 나노입자 제조 시장(기업 규모별)
제23장 지질 나노입자 제조 시장(주요 지역별)
제24장 결론
제25장 이그제큐티브 인사이트
제26장 부록 1 : 표 형식 데이터
제27장 부록 2 : 기업 및 조직 리스트
KSA
영문 목차
영문목차
LIPID NANOPARTICLE MANUFACTURING MARKET: OVERVIEW
As per Roots Analysis, the global lipid nanoparticle manufacturing market is estimated to grow from USD 0.37 billion in the current year to USD 2.53 billion by 2035, at a CAGR of 18.86% during the forecast period, till 2035.
The market sizing and opportunity analysis has been segmented across the following parameters:
Type of Lipid Nanoparticle
Solid Lipid Nanoparticles
Nanostructured Lipid Carriers
Type of Molecule Delivered
Nucleic Acids
Small Molecules
Peptides/ Proteins
Others
Company Size
Very Large and Large
Mid-sized
Small
Therapeutic Area
Infectious Diseases
Oncological Disorders
Blood Disorders
Rare Diseases
Other Disorders
Type of End-user
Pharmaceutical and Biotechnology Companies
Academic and Research Institutes
Other End-users
Key Geographical Regions
North America
Europe
Asia-Pacific
Rest of the World
LIPID NANOPARTICLE MANUFACTURING MARKET: GROWTH AND TRENDS
Over the past few decades, the pharmaceutical industry has witnessed significant growth. This is evident from the continuously growing pipeline of drug candidates that have been marketed or are being evaluated across several development stages. However, low drug solubility / permeability is one of the primary concerns associated with certain pharmacological products. Therefore, players engaged in the pharmaceutical domain are actively trying to identify ways to improve / augment physiochemical properties and drug-like behavior of pharmacological products. Amidst other alternatives, the use of lipid nanoparticles (LNPs) has garnered the attention of many drug developers. This can be attributed to the great versatility of LNPs, in terms of structure and functionality, as well as the ability to enhance the solubility and bioavailability of poorly water-soluble drugs.
Considering the routine operations-related and technical challenges, an increased number of pharmaceutical companies have demonstrated the preference to outsource their respective LNP production operations to specialized service providers. There are numerous benefits of engaging contract manufacturing firms for LNP manufacturing, such as access to new technologies (available with the service provider), larger capacities and greater operational flexibility. As a result, many of the companies are actively trying to consolidate their presence in this field, by entering into strategic alliances to broaden their respective service portfolios and LNP manufacturing capabilities. Given the benefits of using LNPs to improve drug-like properties, the demand for high quality LNPs nanoparticles is likely to drive considerable growth within the specialty contract manufacturing market in the coming years.
The report delves into the current state of the lipid nanoparticle manufacturing market and identifies potential growth opportunities within the industry. Some key findings from the report include:
Over 40 companies claim to offer contract manufacturing services for lipid nanoparticles; majority of these firms are mid-sized players, based in North America.
Several service providers have the necessary capabilities to offer lipid nanoparticle contract manufacturing, across different scales of operation and for encapsulating various types of molecules.
Presently, close to 35 lipid nanoparticle technologies are being offered by companies worldwide in order to manufacture LNP based therapeutics; the market is characterized by the presence of small companies.
Stakeholders have adopted various business models to maximize the gain from LNP technologies; majority of these technologies are intended for drug delivery via injectable route, primarily targeting oncological disorders.
Currently, close to 60 players across the world, claim to provide contract manufacturing services to support the development and production of other types of lipids for various therapeutic purposes.
In order to cater to the rising demand for lipid nanoparticles, service providers are continuously expanding their existing capabilities to drive compliance to evolving industry benchmarks.
In pursuit of obtaining a competitive edge, industry stakeholders are actively advancing and innovating new LNP manufacturing technologies to enhance their respective portfolios.
In order to expand their lipid nanoparticle service portfolios and gain access to emerging technologies, companies are actively entering into various strategic partnerships with various international and local players.
Various mRNA-based therapeutic / vaccine developers across the world are anticipated to forge strategic alliances with LNP contract manufacturing service providers, to further augment their drug portfolio.
The global installed lipid nanoparticle manufacturing capacity is spread across various geographies; majority of this capacity is installed in the production plants located in the US.
Driven by the increasing number of chronic indications (requiring novel personalized therapies), and ongoing research on lipid nanoparticle-based therapeutics, this market is anticipated to grow at a CAGR of 12%, till 2035.
The projected future opportunity for the lipid nanoparticle manufacturing market is likely to be well distributed across different target therapeutic areas, end-users and key geographical regions.
Currently, Solid Lipid Nanoparticles Occupy the Largest Share of the Lipid Nanoparticle Manufacturing Market
Based on the type of lipid nanoparticle, the market is segmented into solid lipid nanoparticles and nanostructured lipid carriers. At present, the solid lipid nanoparticles segment holds the maximum share of the lipid nanoparticle manufacturing market. This trend is likely to remain the same in the forthcoming years. It is worth highlighting that the lipid nanoparticle manufacturing market for nanostructured lipid carriers is likely to grow at a relatively higher CAGR.
Small Molecules are the Fastest Growing Segment of the Lipid Nanoparticle Manufacturing Market
Based on the type of molecule delivered, the market is segmented into nucleic acids, small molecules, proteins/peptides and others. Currently, nucleic acid holds the maximum share of the lipid nanoparticle manufacturing market. However, the small molecules segment is likely to dominate the lipid nanoparticle manufacturing market in the forthcoming decade.
Large and Very Large Companies are Likely to Dominate the Lipid Nanoparticle Manufacturing Market
Based on the company size, the market is segmented into very large and large companies, mid-sized companies and small companies. At present, very large and large companies hold the maximum share of the lipid nanoparticle manufacturing market. This trend is likely to remain the same in the forthcoming years. It is worth highlighting that the lipid nanoparticle manufacturing market for mid-sized companies is likely to grow at a relatively higher CAGR.
Oncological Disorders is the Fastest Growing Segment of the Lipid Nanoparticle Manufacturing Market
Based on the target therapeutic area, the market is segmented into infectious diseases, oncological disorders, blood disorders, rare diseases and other disorders. It is worth highlighting that currently, the oncological disorders segment holds a larger share of the lipid nanoparticle manufacturing market. This trend is likely to remain the same in the coming decade.
Currently, Pharmaceutical and Biotechnology Companies Occupy the Largest Share of the Lipid Nanoparticle Manufacturing Market
Based on the type of end-user, the market is segmented into pharmaceutical and biotechnology companies, academic and research institutes, and other end-users. It is worth highlighting that the majority of the current lipid nanoparticle manufacturing market is captured by pharmaceutical and biotechnology companies. This trend is likely to remain the same in the near future.
North America Accounts for the Largest Share of the Market
Based on key geographical regions, the market is segmented into North America, Europe, Asia-Pacific and Rest of the world. It is worth highlighting that, over the years, the market in Europe is expected to grow at a higher CAGR.
Example Players in the Lipid Nanoparticle Manufacturing Market
Acuitas Therapeutics
Ascendia Pharmaceuticals
Avanti Polar Lipids
BIOVECTRA
CordenPharma
Creative Biolabs
Curapath
Curia
Emergent Biosolutions
EUROAPI
Evonik
Formumax Scientific
Fresinius Kabi
Fujifilm
Integrated Nanotherapeutics
leon-nanodrugs
Matinas BioPharma
Merck
Pantherna Therapeutics
Precision NanoSystems
TLC Biosciences
Primary Research Overview
The opinions and insights presented in this study were influenced by discussions conducted with multiple stakeholders. The research report features detailed transcripts of interviews held with the following industry stakeholders:
Founder and Chief Executive Officer, LIPOSOMA
Former Director, Process Development - Chemistry and Former Acting Manager, Biotech Process Development, BIOVECTRA
Formulation Scientist, OZ Biosciences
LIPID NANOPARTICLE MANUFACTURING MARKET: RESEARCH COVERAGE
Market Sizing and Opportunity Analysis: The report features an in-depth analysis of the lipid nanoparticle manufacturing market, focusing on key market segments, including [A] type of lipid nanoparticle, [B] type of molecule delivered, [C] company size, [D] target therapeutic area, [E] type of end-user and [F] key geographical regions.
Market Landscape (Lipid Nanoparticles Manufacturers): A comprehensive evaluation of lipid nanoparticles manufacturers, considering various parameters, such as [A] year of establishment, [B] company size, [C] location of headquarters, [D] location of manufacturing facility, [E] scale of operation, [F] type of molecule delivered, [F] therapeutic area and [G] type of additional services offered.
Market Landscape (Lipid Nanoparticles Technology Developers): A comprehensive evaluation of lipid nanoparticle technology developers, considering various parameters, such as [A] type of formulation method, [B] type of molecule delivered, [C] compatible dosage form, [D] route of administration, [E] therapeutic area. Additionally, the chapter includes information on the lipid nanoparticle technology developers, including [F] year of establishment, [G] company size (in terms of employee count), [H] location of headquarters, [I] business model and [J] most active players (in terms of number of technologies developed).
Market Landscape (Lipid Contract Manufacturers): A comprehensive evaluation of lipid contract manufacturers, considering various parameters, such as [A] year of establishment, [B] company size (in terms of employee count), [C] location of headquarters, [D] location of manufacturing facilities, [E] scale of operation, [F] type of lipid manufactured, [G] type of product and [H] type of additional services offered.
Company Competitiveness Analysis (Lipid Nanoparticle Contract Manufacturers): A comprehensive competitive analysis of lipid nanoparticle contract manufacturing organizations, examining factors, such as [A] company strength, [B] service strength and [C] number of LNP manufacturing facilities.
Technology Competitiveness Analysis: A comprehensive competitive analysis of lipid nanoparticle technologies, examining factors, such as [A] developer strength, [B] technology strength and [C] technology applicability.
Company Profiles: In-depth profiles of key industry players offering LNP manufacturing services and LNP technology, focusing on [A] company overviews, [B] LNP service / technology portfolio, [C] recent developments and [D] an informed future outlook.
Partnerships and Collaborations: An analysis of partnerships established in this sector, since 2019, covering [A] year of partnership, [B] type of partnership, [C] type of molecule, [D] therapeutic area, [E] type of partner, [F] most active players (in terms of the number of partnerships signed) and [G] regional distribution of partnership activity.
Likely Partner Analysis: A detailed evaluation of mRNA vaccines and therapeutics developers that are most likely to collaborate with lipid nanoparticle manufacturers. This analysis considers various relevant parameters, including [A] developer strength (which takes into account a company's size and experience in this field), [B] pipeline strength (which takes into account the number of mRNA drugs in the pipeline), as well as [C] other mRNA drug related capabilities (which takes into account the target therapeutic area, route of administration and type of candidate).
Make versus Buy Decision Framework: A comprehensive make-or-buy framework that highlights the crucial factors influencing companies (referred to as sponsors in later sections) in their decision to either outsource LNP manufacturing operations or establish in-house capabilities.
Capacity Analysis: Estimation of global installed lipid nanoparticle contract manufacturing capacity, derived from data provided by various stakeholders in the public domain. This analysis emphasizes the distribution of the available capacity on the basis of [A] company size (small, mid-sized, and large and very large companies), [B] scale of operation (preclinical, clinical and commercial) and [C] geography (North America, Europe and Asia-Pacific).
Market Impact Analysis: The report analyzes various factors such as drivers, restraints, opportunities, and challenges affecting the market growth.
KEY QUESTIONS ANSWERED IN THIS REPORT
How many companies are currently engaged in this market?
Which are the leading companies in this market?
What is the global installed capacity of lipid nanoparticle contract manufacturers?
What factors are likely to influence the evolution of this market?
What is the current and future market size?
What is the CAGR of this market?
How is the current and future market opportunity likely to be distributed across key market segments?
REASONS TO BUY THIS REPORT
The report provides a comprehensive market analysis, offering detailed revenue projections of the overall market and its specific sub-segments. This information is valuable to both established market leaders and emerging entrants.
Stakeholders can leverage the report to gain a deeper understanding of the competitive dynamics within the market. By analyzing the competitive landscape, businesses can make informed decisions to optimize their market positioning and develop effective go-to-market strategies.
The report offers stakeholders a comprehensive overview of the market, including key drivers, barriers, opportunities, and challenges. This information empowers stakeholders to stay abreast of market trends and make data-driven decisions to capitalize on growth prospects.
ADDITIONAL BENEFITS
Complimentary PPT Insights Packs
Complimentary Excel Data Packs for all Analytical Modules in the Report
10% Free Content Customization
Detailed Report Walkthrough Session with Research Team
Free Updated report if the report is 6-12 months old or older
TABLE OF CONTENTS
1. PREFACE
1.1. Introduction
1.2. Key Market Insights
1.3. Scope of the Report
1.4. Inclusions and Exclusions
1.5. Key Questions Answered
1.6. Chapter Outlines
2. RESEARCH METHODOLOGY
2.1. Chapter Overview
2.2. Research Assumptions
2.3. Project Methodology
2.4. Forecast Methodology
2.5. Robust Quality Control
2.6. Key Market Segmentations
2.7. Key Considerations
2.7.1. Demographics
2.7.2. Economic Factors
2.7.3. Government Regulations
2.7.4. Supply Chain
2.7.5. COVID Impact / Related Factors
2.7.6. Market Access
2.7.7. Healthcare Policies
2.7.8. Industry Consolidation
3. ECONOMIC AND OTHER PROJECT SPECIFIC CONSIDERATIONS
3.1. Chapter Overview
3.2. Market Dynamics
3.2.1. Time Period
3.2.1.1. Historical Trends
3.2.1.2. Current and Forecasted Estimates
3.2.2. Currency Coverage
3.2.2.1. Overview of Major Currencies Affecting the Market
3.2.2.2. Impact of Currency Fluctuations on the Industry
3.2.3. Foreign Exchange Impact
3.2.3.1. Evaluation of Foreign Exchange Rates and Their Impact on Market
3.2.3.2. Strategies for Mitigating Foreign Exchange Risk
3.2.4. Recession
3.2.4.1. Historical Analysis of Past Recessions and Lessons Learnt
3.2.4.2. Assessment of Current Economic Conditions and Potential Impact on the Market
3.2.5. Inflation
3.2.5.1. Measurement and Analysis of Inflationary Pressures in the Economy
3.2.5.2. Potential Impact of Inflation on the Market Evolution
4. EXECUTIVE SUMMARY
5. INTRODUCTION
5.1. Chapter Overview
5.2. Overview of Lipids
5.3 Introduction to Lipid Nanoparticles
5.3.1. Types of Lipid Nanoparticles
5.3.1.1. Solid Lipid Nanoparticles
5.3.1.2. Nanostructured Lipid Carriers
5.3.2. Advantages of Lipid Nanoparticles
5.3.3. Applications of Lipid Nanoparticles in Pharmaceutical Industry
5.3.3.1. Cancer Treatment
5.3.3.2. Gene Therapy
5.3.3.3. Vaccine Development
5.3.3.4. Medical Imaging / Diagnostics
5.3.3.5. Additional Applications
5.4. Challenges Associated with Lipid Nanoparticle Manufacturing
5.5. Need for Outsourcing Lipid Nanoparticle Manufacturing
5.6. Concluding Remarks
6. LIPID NANOPARTICLES: SERVICE PROVIDERS LANDSCAPE
6.1. Chapter Overview
6.2. Lipid Nanoparticle Manufacturing: List of Service Providers
6.2.1 Analysis by Year of Establishment
6.2.2 Analysis by Company Size
6.2.3 Analysis by Location of Headquarters
6.2.4 Analysis by Company Size and Location of Headquarters
6.2.5 Analysis by Location of Lipid Nanoparticle Manufacturing Facility
6.2.6 Analysis by Scale of Operation
6.2.7 Analysis by Type of Molecule Delivered
6.2.8 Analysis by Therapeutic Area
6.2.9 Analysis by Type of Additional Services Offered
7. LIPID NANOPARTICLES: TECHNOLOGY LANDSCAPE
7.1. Chapter Overview
7.2. Lipid Nanoparticle: Technology Landscape
7.2.1. Analysis by Type of Formulation Method
7.2.2. Analysis by Type of Molecule Delivered
7.2.3. Analysis by Compatible Dosage Form
7.2.4. Analysis by Routes of Administration
7.2.5. Analysis by Therapeutic Area
7.3. Lipid Nanoparticle Technologies: List of Technology Developers
7.3.1. Analysis by Year of Establishment
7.3.2. Analysis by Company Size
7.3.3. Analysis by Location of Headquarters
7.3.4. Analysis by Company Size and Location of Headquarters
7.3.5. Analysis by Business Model
7.3.6. Most Active Players: Analysis by Number of Technologies
8. OTHER TYPES OF LIPIDS: SERVICE PROVIDERS LANDSCAPE
8.1. Chapter Overview
8.2. Other Types of Lipids: List of Service Providers
8.2.1 Analysis by Year of Establishment
8.2.2 Analysis by Company Size
8.2.3 Analysis by Location of Headquarters
8.2.4 Analysis by Company Size and Location of Headquarters
8.2.5. Analysis by Location of Manufacturing Facility
8.2.6. Analysis by Scale of Operation
8.2.7 Analysis by Type of Lipid Manufactured
8.2.8. Analysis by Scale of Operation and Type of Lipid Manufactured
8.2.9. Analysis by Type of Product
8.2.10. Analysis by Type of Additional Services Offered
8.2.11. Analysis by Type of Product and Type of Additional Services Offered
9. COMPANY COMPETITIVENESS ANALYSIS
9.1. Chapter Overview
9.2. Assumptions and Key Parameters
9.3. Methodology
9.4. Lipid Nanoparticle Manufacturing Service Providers: Company Competitiveness Analysis
9.4.1. Company Competitiveness Analysis: Small Players
9.4.2. Company Competitiveness Analysis: Mid-sized Players
9.4.3. Company Competitiveness Analysis: Large and Very Large Players
