Protein Expression Market by System (Mammalian, Non-mammalian ), Offering (Kits & Reagents, Vectors, Competent Cells, Services), Application (Industrial, Therapeutic, Research), and End User - Global Forecast to 2030
Protein Expression Market Size, Share, Forecast, & Trends Analysis by System (Mammalian [CHO, HEK 293], Non-mammalian [Bacterial, Insect]), Offering (Kits & Reagents, Competent Cells, Services), Application, and End User - Global Forecast to 2030
The protein expression market is projected to reach $5 billion by 2030 at a CAGR of 7.6% from 2023 to 2030.
Succeeding extensive secondary and primary research and an in-depth analysis of the market scenario, the report provides an analysis of key industry drivers, restraints, opportunities, and challenges.
The growing biopharmaceutical market, the rising demand for recombinant proteins, supportive government initiatives, and funding for life science research are driving the growth of this market. However, the high costs of protein-based research and the lack of skilled professionals restrain the growth of this market. Furthermore, emerging economies are expected to offer significant growth opportunities for players operating in the protein expression market. However, complexities in laboratory transformation parameters are a challenge limiting market growth.
The report offers a competitive landscape based on an extensive assessment of the product portfolios, geographic presence, and key strategic developments of leading market players during the last four years (2020-2023). The key players operating in the protein expression market are Thermo Fisher Scientific Inc. (U.S.), Promega Corporation (U.S.), Merck KGaA (Germany), Bio-Rad Laboratories, Inc. (U.S.), Takara Holdings Inc. (Japan), GenScript Biotech Corporation (U.S.), Qiagen N.V. (Germany), Agilent Technologies, Inc. (U.S.), Danaher Corporation (U.S.), and Becton, Dickinson and Company (U.S.).
Based on system, in 2023, the Chinese Hamster Ovary (CHO) cell line segment is expected to account for the largest share of the mammalian protein expression market. The large market share of this segment is attributed to the popularity of CHO cell lines in the production of biologics, the high similarity of CHO cells to the human cell system, and the high reproducibility of CHO cells.
Based on offering, the services segment is expected to grow at the highest CAGR during the forecast period. The high growth of this segment is driven by the increasing outsourcing of operations by pharma & biotech companies, the rising demand for biopharmaceuticals, collaborations between industry and academia for rapid bioproduction, and the growing demand for recombinant proteins in the non-healthcare sector.
Based on application, in 2023, the therapeutic segment is estimated to account for the largest share of the protein expression market. The large market share of this segment is attributed to the increasing incidence of diseases requiring therapeutic approaches for treatment and growth in R&D for therapeutic protein production.
Based on end user, in 2023, the contract research organizations segment is estimated to account for the largest share of the protein expression market. The large market share of this segment can be attributed to the increase in research activities and growth in outsourcing for the development of biologics.
An in-depth analysis of the geographical scenario in the protein expression market provides detailed qualitative and quantitative insights into five major geographies (North America, Europe, Asia-Pacific, Latin America, and the Middle East & Africa) along with the coverage of major countries in each region. In 2023, North America is expected to account for the largest share of the protein expression market. Furthermore, in 2023, the U.S. is expected to account for the major share of the protein expression market in North America. The large share of this market is primarily attributed to the presence of key market players, growth in R&D activities, and the significant volume of bioproduction.
Scope of the Report:
Protein Expression Market Assessment-by System
Mammalian Cell Expression Systems
Chinese Hamster Ovary (CHO) Cell Lines
HEK 293 Cell Lines
Other Mammalian Cell Lines
Non-mammalian Cell Expression Systems
Bacterial Cell Lines
Insect Cell Lines
Yeast Cell Lines
Plant Cell Lines
Algal-based Cell Lines
Cell-free Expression System
Note: Other mammalian cell lines include baby hamster kidney cells, non-secreting murine myeloma cells, and PER.C6.
Protein Expression Market Assessment-by Offering
Instruments
Kits & Reagents
Competent Cells
Chemically Competent Cells
Electrocompetent Cells
Expression Vectors
Services
Protein Expression Market Assessment-by Application
Therapeutic
Research
Industrial
Protein Expression Market Assessment-by End User
Pharmaceutical & Biotechnology Industry
Contract Research Organizations
Academic & Research Institutes
Protein Expression Market Assessment-by Geography
North America
U.S.
Canada
Europe
Germany
France
Italy
U.K.
Spain
Rest of Europe (RoE)
Asia-Pacific (APAC)
China
Japan
India
Rest of Asia-Pacific (RoAPAC)
Latin America
Middle East & Africa
TABLE OF CONTENTS
1. Introduction
1.1. Market Definition & Scope
1.2. Market Ecosystem
1.3. Currency & Limitations
1.4. Key Stakeholders
2. Research Methodology
2.1. Research Approach
2.2. Process of Data Collection & Validation
2.2.1. Secondary Research
2.2.2. Primary Research/Interviews with Key Opinion Leaders of the Industry
2.3. Market Sizing and Forecast
2.3.1. Market Estimation Approach
2.3.2. Growth Forecast Approach
2.3.3. Market Share Analysis
2.4. Assumptions for this Study
3. Executive Summary
4. Market Insights
4.1. Market Overview
4.2. Drivers
4.2.1. Growth in the Biopharmaceutical Market
4.2.2. Growing Demand for Recombinant Proteins
4.2.3. Rising Government Initiatives and Funding for Life Science Research
4.3. Restraints
4.3.1. Shortage of Skilled Professionals
4.3.2. High Cost of Protein-based Research
4.4. Opportunities
4.4.1. Potential Emerging Economies
4.5. Challenges
4.5.1. Complexities in Laboratory Transformation Parameters
4.6. Industry Trends
4.7. Parent/Adjacent Market Analysis
4.8. Regulatory Analysis
5. Protein Expression Market Assessment-by System
5.1. Overview
5.2. Mammalian Cell Expression System
5.2.1. Chinese Hamster Ovary (CHO) Cell Lines
5.2.2. HEK 293 Cell Lines
5.2.3. Other Mammalian Cell Lines
5.3. Non-mammalian Cell Expression System
5.3.1. Bacterial Cell Lines
5.3.2. Insect Cell Lines
5.3.3. Yeast Cell Lines
5.3.4. Plant Cell Lines
5.3.5. Algal Cell Lines
5.4. Cell-Free Expression System
6. Protein Expression Market Assessment-by Product & Services
6.1. Overview
6.2. Instruments
6.3. Kits & Reagents
6.4. Competent Cells
6.4.1. Chemically Competent Cells
6.4.2. Electrocompetent Cells
6.5. Expression Vectors
6.6. Services
7. Protein Expression Market Assessment-by Application
7.1. Overview
7.2. Therapeutic Application
7.3. Industrial Application
7.4. Research Application
8. Protein Expression Market Assessment-by End User
8.1. Introduction
8.2. Pharmaceutical and Biotechnology Industry
8.3. Contract Research Organizations (CROs)
8.4. Academic and Research Institutes
9. Protein Expression Market Assessment-by Geography