Human Microbiome Market by Product (Drugs, Probiotics, Prebiotics, Synbiotics, Diagnostics), Disease (Infectious, Gastrointestinal), Route (Oral, Rectal), CDMO (Formulation, Strain Engineering), Type (BCT/FMT, Live Bacteria) - Global Forecast to 2031
The Human Microbiome market is expected to reach USD 7.09 billion in 2031 from USD 1.40 billion in 2024, at a CAGR of 31.0% during the forecast period.
Scope of the Report
Years Considered for the Study
2024-2031
Base Year
2024
Forecast Period
2025-2031
Units Considered
Value (USD billion)
Segments
Product, Disease, Drugs & Supplements Type, Drugs & Supplements Route of Administration, End User, Manufacturing Services, and Region
Regions covered
North America, Europe, the Asia Pacific, Latin America, the Middle East, and Africa
Factors such as the collaborative efforts between the microbiome industry and academia for microbiome research and the growing demand for personalized medicine are driving the growth of the human microbiome market. However, complex regulatory policies adversely impact the commercialization of microbiomes, restraining market growth.
The probiotics segment accounted for the largest share of the human microbiome supplements segment in 2024.
The market is segmented into human microbiome drugs, human microbiome supplements, and human microbiome diagnostics. The human microbiome supplements are analyzed across three key products: probiotics, prebiotics, and synbiotics. The segment with the biggest share in the human microbiome market in 2024 is probiotics. This dominance is attributed to their widespread use, strong consumer awareness, and established presence in over-the-counter health and wellness products. Probiotics are commonly used to support digestive health, boost immunity, and maintain gut microbial balance, making them a routine part of preventive healthcare. They are available in various formats, including capsules, powders, beverages, and functional foods, enhancing accessibility and consumer adoption. Additionally, a large body of clinical research supports the efficacy of specific probiotic strains, reinforcing trust among consumers and healthcare providers. The ability to pair probiotics with other bioactives like prebiotics or vitamins has further expanded their appeal across various demographics. Collectively, these factors have made probiotics the leading product type in the human microbiome supplements segment.
In 2024, the gastrointestinal diseases segment accounted for the largest share of the market.
The human microbiome market is segmented into gastrointestinal diseases, infectious diseases, endocrine & metabolic disorders, and other diseases. In 2024, the gastrointestinal diseases segment accounted for the largest share of the market. This is driven by the strong association between gut microbiota and conditions such as irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), ulcerative colitis, and Crohn's disease. These chronic disorders have a high global prevalence and often require long-term management, creating demand for alternative and adjunctive therapies that target the gut microbiome.
A growing body of research supports the role of microbial imbalances in the development and progression of gastrointestinal conditions, prompting increased investment in microbiome-based diagnostics and treatments. Several clinical-stage products targeting IBD and IBS are in development, reflecting scientific interest and unmet patient needs. The availability of microbiome supplements aimed at digestive health, such as probiotics and synbiotics, has further expanded consumer access and contributed to market growth in this segment.
In 2024, North America accounted for the largest share of the human microbiome market.
North America accounted for the largest share of the human microbiome market in 2024. This is due to several factors, including a strong presence of key market players, advanced healthcare infrastructure, and high levels of investment in microbiome research and development. The region hosts numerous clinical trials and academic collaborations focused on microbiome science, particularly in the United States. Regulatory support has also contributed to market growth, with the US FDA approving the first microbiome-based therapeutics, such as VOWST and Rebyota, setting important regulatory precedents. In addition, North America has a large and growing consumer base for microbiome supplements, particularly probiotics and synbiotics, driven by rising awareness of gut health and preventive wellness. High healthcare spending, increasing prevalence of chronic diseases, and favorable reimbursement policies further reinforce the leading position of North America in the global human microbiome market.
The primary interviews conducted for this report can be categorized as follows:
By Respondent: Tier 1-25%, Tier 2-35%, and Tier 3- 40%
By Designation: C-level Executives - 55%, Directors- 20%, and Others- 25%
By Region: North America -45%, Europe - 20%, Asia Pacific -20%, Latin America -10%, the Middle East- 3%, and Africa-2%
Seres Therapeutics (US), Ferring B.V. (Switzerland), BiomeBank (Australia), Seed Health, Inc. (US), International Flavors & Fragrances Inc. (US), Pendulum (US), Biohm Technologies (US), Actial Farmaceutica Srl (Italy), OptiBiotix Health Plc (UK), resbiotic (US), Infinant Health Inc (US), BioGaia (Sweden), ExeGi Pharma (US), Finch Therapeutics Group, Inc. (US), Infant Bacterial Therapeutics AB (Sweden), MaaT Pharma (France), Microba (Australia), Viome Life Sciences, Inc. (US), and Genova Diagnostics (US) are some of the key companies offering human microbiome drugs & supplements.
Research Coverage
This research report categorizes the Human Microbiome market by Product (Human Microbiome Drugs, Human Microbiome Supplements [Probiotics, Prebiotics, Synbiotics], Human Microbiome Diagnostics), Disease (Infectious disease, Gastrointestinal Disease, Endocrine, and metabolic disorders, Cancer, and Other Diseases), Drugs & Supplements Type (Bacterial Consortia Transplantation (BCT)/ Fecal Microbiota Transplantation (FMT), Peptides, Live Bacteria Products, and Others), Drugs & Supplements Route of Administration (Oral, Rectal), End User (Hospitals & Clinics, Long-term care Facilities, Other End Users), Manufacturing Service (Strain Development & Optimization, Fermentation & Downstream Processing, Formulation & Fill/Finish, Other Services) and by region (North America, Europe, Asia Pacific, Latin America, Middle East, and Africa). The scope of the report covers detailed information regarding the major factors, such as drivers, challenges, opportunities, and restraints influencing the growth of the Human Microbiome market. A detailed analysis of the key industry players has been done to provide insights into their business overview, service portfolio, key strategies such as collaborations, partnerships, expansions, agreements, and acquisitions, and recent developments associated with the Human Microbiome market. Competitive analysis of top players and upcoming startups in the human microbiome market ecosystem is covered in this report.
The scope of the report covers detailed information regarding the primary factors, such as drivers, restraints, challenges, and opportunities, influencing the growth of the human microbiome market. A thorough analysis of the key industry players has been conducted to provide insights into their business overview, solutions, and services; key strategies; new product & service launches, acquisitions, and recent developments associated with the human microbiome market. This report covers the competitive analysis of upcoming startups in the human microbiome market ecosystem.
Key Benefits of Buying the Report
The report will help market leaders/new entrants by providing them with the closest approximations of the revenue numbers for the overall Human Microbiome market and its subsegments. It will also help stakeholders better understand the competitive landscape and gain more insights to better position their business and make suitable go-to-market strategies. This report will enable stakeholders to understand the market's pulse and provide them with information on the key market drivers, restraints, opportunities, and challenges.
The report provides insights on the following pointers:
Analysis of key drivers (Collaborative initiatives between organizations, academia, and the microbiome industry, Increase in the number of Startups,/SMEs exploring the microbiome niche, Advancements in microbiome sequencing), restraints (Adverse impact of complex regulatory policies on commercialization of microbiomes, High investment in commercialization of microbiome drugs), opportunities (Increase in demand for personalized medicine, and Emergence of synbiotics), and challenges (Slow patient adoption of microbiome-based therapies and Complexities involved in development of microbiome therapies) influencing the growth of the market.
Product Development/Innovation: Detailed insights on newly launched products of the human microbiome market
Market Development: Comprehensive information about lucrative markets - the report analyses the market across varied regions.
Market Diversification: Exhaustive information about new services, untapped geographies, recent developments, and investments in the Human Microbiome market
Competitive Assessment: Seres Therapeutics (US), Ferring B.V. (Switzerland), BiomeBank (Australia), Seed Health, Inc. (US), International Flavors & Fragrances Inc. (US), Pendulum (US), Biohm Technologies (US), Actial Farmaceutica Srl (Italy), OptiBiotix Health Plc (UK), resbiotic (US), Infinant Health Inc (US), BioGaia (Sweden), ExeGi Pharma (US), Finch Therapeutics Group, Inc. (US), Infant Bacterial Therapeutics AB (Sweden), MaaT Pharma (France), Microba (Australia), Viome Life Sciences, Inc. (US), and Genova Diagnostics (US) among others in the market.
TABLE OF CONTENTS
1 INTRODUCTION
1.1 STUDY OBJECTIVES
1.2 MARKET DEFINITION
1.3 STUDY SCOPE
1.3.1 MARKET SEGMENTATION AND REGIONAL SCOPE
1.3.2 INCLUSIONS AND EXCLUSIONS
1.3.3 YEARS CONSIDERED
1.4 CURRENCY CONSIDERED
1.5 STAKEHOLDERS
1.6 SUMMARY OF CHANGES
2 RESEARCH METHODOLOGY
2.1 RESEARCH DATA
2.1.1 SECONDARY DATA
2.1.2 PRIMARY DATA
2.2 MARKET SIZE ESTIMATION METHODOLOGY
2.2.1 INSIGHTS FROM PRIMARY EXPERTS
2.2.2 SEGMENTAL MARKET SIZE ESTIMATION
2.3 GROWTH RATE PROJECTIONS
2.4 MARKET BREAKDOWN AND DATA TRIANGULATION
2.5 RESEARCH ASSUMPTIONS
2.6 RESEARCH LIMITATIONS
2.7 RISK ANALYSIS
3 EXECUTIVE SUMMARY
4 PREMIUM INSIGHTS
4.1 HUMAN MICROBIOME MARKET OVERVIEW
4.2 NORTH AMERICA: HUMAN MICROBIOME MARKET, BY TYPE AND COUNTRY, 2024
4.3 HUMAN MICROBIOME MARKET, BY TYPE, 2025 VS. 2031
4.4 HUMAN MICROBIOME MARKET: GEOGRAPHIC GROWTH OPPORTUNITIES
4.5 HUMAN MICROBIOME MARKET, BY END USER, 2025
5 MARKET OVERVIEW
5.1 INTRODUCTION
5.2 MARKET DYNAMICS
5.2.1 DRIVERS
5.2.1.1 Collaborative initiatives between organizations and academia
5.2.1.2 Increasing number of startups/SMEs exploring microbiome
5.2.1.3 Advancements in microbiome sequencing
5.2.2 RESTRAINTS
5.2.2.1 Complex regulatory policies
5.2.2.2 High investments in commercializing microbiome drugs
5.2.3 OPPORTUNITIES
5.2.3.1 Increasing demand for personalized medicines
5.2.3.2 Emergence of postbiotics
5.2.4 CHALLENGES
5.2.4.1 Slow patient adoption of microbiome-based therapies
5.2.4.2 Complexities in developing microbiome therapies
5.3 TRENDS/DISRUPTIONS IMPACTING CUSTOMER BUSINESS
5.3.1 DISRUPTION INDEX: MARKET READINESS VS. ADOPTION VS. MATURITY
5.3.1.1 Market readiness
5.3.1.2 Adoption
5.3.1.3 Maturity
5.4 PRICING ANALYSIS
5.4.1 AVERAGE SELLING PRICE TREND OF PRODUCTS, BY KEY PLAYER, 2022-2024
5.4.2 AVERAGE SELLING PRICE TREND OF PRODUCTS, BY REGION, 2022-2024
5.5 VALUE CHAIN ANALYSIS
5.5.1 HUMAN MICROBIOME DRUGS
5.5.2 HUMAN MICROBIOME SUPPLEMENTS
5.5.3 HUMAN MICROBIOME DIAGNOSTICS
5.6 ECOSYSTEM ANALYSIS
5.6.1 ECOSYSTEM SHIFT
5.6.1.1 Specialized raw material and data suppliers
5.6.1.2 Hot-bet innovator startups
5.6.1.3 Integrated end users and prosumer models
5.6.1.4 Regulatory and quality assurance orchestrators
5.6.1.5 Diagnostics-driven personalization
5.6.1.6 Microbiome-as-a-Service (Maas)
5.6.2 EMERGING BUSINESS MODELS
5.6.2.1 Emerging B2C model
5.6.2.2 Personalized supplements model
5.6.3 INTERCONNECTED MARKET DYNAMICS
5.7 INVESTMENT AND FUNDING SCENARIO
5.7.1 MAJOR INVESTMENTS AND FUNDING BY KEY MARKET PLAYERS
5.7.2 OTHER INVESTMENTS AND FUNDING
5.8 TECHNOLOGY ANALYSIS
5.8.1 KEY TECHNOLOGIES
5.8.1.1 Whole-genome sequencing
5.8.1.2 16s RNA sequencing method
5.8.1.3 Nanopore sequencing
5.8.2 COMPLEMENTARY TECHNOLOGIES
5.8.2.1 Metatranscriptomics
5.8.2.2 Metagenomics
5.8.2.3 Metabolomics
5.8.3 ADJACENT TECHNOLOGIES
5.8.3.1 Sample preparation
5.8.3.2 Data analysis
5.8.3.3 Library synthesis
5.9 PATENT ANALYSIS
5.10 KEY CONFERENCES AND EVENTS, 2025-2026
5.11 CASE STUDY ANALYSIS
5.11.1 EFFECT OF REBYOTA ON QUALITY OF LIFE IN PATIENTS WITH RECURRENT CLOSTRIDIOIDES DIFFICILE INFECTION
5.11.2 ECOSPOR IV STUDY OF VOWST FOR CLOSTRIDIOIDES DIFFICILE INFECTION
5.11.3 DELONG#3 STUDY FOR QUALITY OF LIFE IMPROVEMENT BY VSL#3 PROBIOTIC IN POST-COVID-19 PATIENTS
5.12 TARIFF AND REGULATORY ANALYSIS
5.12.1 TARIFF DATA (HS CODE 3002.90)
5.12.2 REGULATORY LANDSCAPE
5.12.2.1 North America
5.12.2.1.1 US
5.12.2.1.2 Canada
5.12.2.2 Europe
5.12.2.2.1 UK
5.12.2.3 Asia Pacific
5.12.2.3.1 China
5.12.2.3.2 Japan
5.12.2.3.3 South Korea
5.12.2.3.4 Australia
5.12.2.3.5 Rest of Asia Pacific
5.12.3 REGULATORY BODIES, GOVERNMENT AGENCIES, AND OTHER ORGANIZATIONS
5.13 PORTER'S FIVE FORCES ANALYSIS
5.13.1 BARGAINING POWER OF SUPPLIERS
5.13.2 BARGAINING POWER OF BUYERS
5.13.3 THREAT OF NEW ENTRANTS
5.13.4 THREAT OF SUBSTITUTES
5.13.5 INTENSITY OF COMPETITIVE RIVALRY
5.14 KEY STAKEHOLDERS AND BUYING CRITERIA
5.14.1 KEY STAKEHOLDERS IN BUYING PROCESS
5.14.2 BUYING CRITERIA
5.15 PIPELINE ANALYSIS
5.16 IMPACT OF AI/GEN AI ON HUMAN MICROBIOME MARKET
5.16.1 INTRODUCTION
5.16.2 MARKET POTENTIAL OF AI IN HUMAN MICROBIOME MARKET
5.16.3 AI USE CASES
5.16.4 KEY PLAYERS IMPLEMENTING AI
5.16.5 FUTURE OF GENERATIVE AI IN HUMAN MICROBIOME MARKET
5.17 IMPACT OF US TARIFF ON HUMAN MICROBIOME MARKET
5.17.1 KEY TARIFF RATES
5.17.2 PRICE IMPACT ANALYSIS
5.17.3 KEY IMPACT ON COUNTRY/REGION
5.17.3.1 US
5.17.3.2 Europe
5.17.3.3 Asia Pacific
5.17.3.4 Rest of the World
5.17.4 IMPACT ON END-USE INDUSTRY
5.17.4.1 Hospitals and clinics
5.17.4.2 Long-term care facilities
5.18 MANAGING GLP-1 SIDE EFFECTS WITH MICROBIOME INTERVENTIONS
5.19 FUTURE TRENDS IN HUMAN MICROBIOME MARKET
5.19.1 TYPE
5.19.2 DISEASE
5.19.3 END USER
6 HUMAN MICROBIOME MARKET, BY PRODUCT
6.1 INTRODUCTION
6.2 DRUGS
6.2.1 GROWING PIPELINE OF MICROBIOME-BASED DRUGS IN LATE-STAGE CLINICAL TRIALS TO DRIVE MARKET
6.3 SUPPLEMENTS
6.3.1 PROBIOTICS
6.3.1.1 Increasing consumer awareness about probiotics for improved gut health and immunity to aid growth
6.3.2 PREBIOTICS
6.3.2.1 Rising development of targeted prebiotics to expedite growth
6.3.3 SYNBIOTICS
6.3.3.1 Growing demand for personalized treatment and rising incidence of dysbiosis to fuel market
6.4 DIAGNOSTICS
6.4.1 INCREASING PRODUCT LAUNCHES AND TECHNOLOGY TRANSFER TO FACILITATE GROWTH
7 HUMAN MICROBIOME DRUGS & SUPPLEMENTS MARKET, BY TYPE