The global market for protein expression is estimated to grow from $4.7 billion in 2025 to reach $7.9 billion by 2030, at a compound annual growth rate (CAGR) of 10.9% from 2025 through 2030.
The North American market for protein expression is estimated to grow from $1.9 billion in 2025 to reach $3.1 billion by 2030, at a CAGR of 10.6% from 2025 through 2030.
The Asia-Pacific market for protein expression is estimated to grow from $951.8 million in 2025 to reach $1.7 billion by 2030, at a CAGR of 12.3% from 2025 through 2030.
Report Scope
The report provides an overview of the global protein expression market and analyzes key market trends. Global revenue ($ million) for the base year 2024 and estimated data for the forecast period, 2025 through 2030, are also included. The market is segmented into expression system, product types, application, end user and regions. The regions covered in this study are North America, Europe, Asia-Pacific (APAC) and the Rest of the World (RoW), with a focus on major countries in these regions.
The report examines trends and challenges that affect the market and vendor landscape; analyzes environmental, social and corporate governance (ESG) developments; and discusses emerging technologies related to the market.
The report concludes with an analysis of the competitive landscape, providing rankings and market shares of key companies in the global protein expression market. A dedicated section of company profiles provides an overview, key financials, product portfolios and recent developments of leading companies, including a patent analysis.
Report Includes
- 52 data tables and 65 additional tables
- An overview of the global market for protein expression
- In-depth analysis of global market trends, featuring historical revenue data for 2022-2024, estimated figures for 2025, as well as forecasts for 2030. This analysis includes projections of compound annual growth rates (CAGRs) through 2030
- Evaluation of the current market size and revenue growth prospects specific to the protein expression, accompanied by a market share analysis by system type, product, application, end user and region
- Analysis of current and future demand in the global protein expression, along with a detailed analysis of the competitive environment, market regulations and reimbursement practices
- Analysis of drivers, challenges and opportunities affecting market growth
- Coverage of evolving technologies, the current and future market potential, R&D activities, growth strategies, new product pipeline, regulatory framework and reimbursement scenarios, and ESG trends of the market
- Market share analysis of the key market participants in the protein expression industry, along with their research priorities, product portfolios, global rankings and competitive landscape
- Profiles of the major companies, including Thermo Fisher Scientific Inc., Bio-Rad Laboratories Inc., Merck KGaA, Sartorius AG and Agilent Technologies Inc.
Table of Contents
Chapter 1 Executive Summary
- Market Outlook
- Scope of Report
- Market Summary
- Market Growth Factors
- Emerging Technologies
- Segmental Analysis
- Regional Analysis
- Conclusion
Chapter 2 Market Overview
- Technology Background
- Protein Expression Workflow
- Choice of Cell Type
- Choice of Plasmid
- Choice of Cell Expression System
- Introduction to Protein Expression Systems
- Protein Synthesis Machinery
- Cloning Technologies
- Constitutive and Inducible Promoters Commonly Used in Recombinant Protein Expression Systems
- Production of Recombinant Proteins
- Recombinant Protein Expression Methods
- Comparison of Expression Systems
- Post-Translational Processing
- Problems Associated with the Production of Protein
- Loss of Expression
- Macroeconomic Factors Analysis
- PESTEL Analysis
- Impact of U.S. Tariff Laws on the Protein Expression Market
- Porter's Five Forces Analysis
- Bargaining Power of Buyers: Moderate
- Bargaining Power of Suppliers: Moderate
- Threat of Substitute Products: Low
- Threat of New Entrants: Moderate
- Industry Competition: High
Chapter 3 Market Dynamics
- Overview
- Market Drivers
- Demand for Therapeutic Proteins and Biologics
- Investments in Biopharmaceuticals
- Technological Advances in Protein Expression Systems
- Market Restraints
- Complex Government Regulations and Policies
- High Cost of Protein Drugs
- Market Opportunities
- Demand for Biopharmaceuticals in Emerging Countries
- Expanded Applications for CRISPR Technology
Chapter 4 Regulatory Landscape
- Overview
- The U.S.
- Europe
- Asia-Pacific
- Rest of the World
Chapter 5 Emerging Technologies and New Developments
- Overview
- CRISPR/Cas9 Genome Editing
- Synthetic Biology
- AI Integration in Protein Expression
Chapter 6 Market Segmentation Analysis
- Segmentation Breakdown
- Market Breakdown by System Type
- Key Takeaways
- Prokaryotic Expression Systems
- Mammalian Cell Expression Systems
- Yeast Expression Systems
- Insect Cell Expression Systems
- Cell-Free Expression Systems
- Algal-based Expression Systems
- Market Breakdown by Product Type
- Key Takeaways
- Reagents
- Expression Vectors
- Competent Cells
- Instruments
- Services
- Market Breakdown by Application
- Key Takeaways
- Therapeutics
- Industrial
- Research
- Market Breakdown by End User
- Key Takeaways
- Pharmaceutical and Biotechnology Companies
- Contract Research Organizations
- Academic Research Institutes
- Others
- Geographic Breakdown
- Market Breakdown by Region
- Key Takeaways
- North America
- Europe
- Asia-Pacific
- Rest of the World
Chapter 7 Competitive Intelligence
- Key Takeaways
- Top Companies' Ranking, 2024
- Strategic Analysis
Chapter 8 Sustainability in the Protein Expression Market: ESG Perspective
- Sustainability in the Protein Expression Market
- Understanding ESG Data
- ESG Performance Analysis
- Environmental Performance
- Social Performance
- Governance Performance
- Concluding Remarks from BCC
Chapter 9 Patent Landscape
- Overview
- Patents, by Year
- Patents, by Leading Applicants
- Patents, by Document Type
- Recent Patents Relating to Protein Expression Technology
Chapter 10 Appendix
- Methodology
- References
- Abbreviations
- Company Profiles
- AGILENT TECHNOLOGIES INC.
- BIO-RAD LABORATORIES INC.
- CORNING INC.
- DANAHER CORP.
- FUJIFILM CELLULAR DYNAMICS INC.
- GENSCRIPT
- LONZA
- MERCK KGAA
- NEW ENGLAND BIOLABS
- ORIGENE TECHNOLOGIES INC.
- PROMEGA CORP.
- PROTEOGENIX INC.
- QIAGEN
- SARTORIUS AG
- THERMO FISHER SCIENTIFIC INC.
