CAR T¼¼Æ÷Ä¡·á ½ÃÀå ±Ô¸ð, Á¡À¯À², µ¿Ç⠺м® º¸°í¼ : Á¦Ç°º°(Abecma, Breyanzi), ÀûÀÀÁõº°(¸²ÇÁÁ¾, ¹éÇ÷º´, ´Ù¹ß¼º°ñ¼öÁ¾), ÃÖÁ¾ ¿ëµµº°, Áö¿ªº°, ºÎ¹®º° ¿¹Ãø(2023-2030³â)
CAR T-cell Therapy Market Size, Share & Trends Analysis Report by Product (Abecma, Breyanzi), By Disease Indication (Lymphoma, Leukemia, Multiple Myeloma), By End-use, By Region, And Segment Forecasts, 2023 - 2030
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Grand View Research, Inc.ÀÇ ÃֽŠº¸°í¼¿¡ µû¸£¸é ¼¼°èÀÇ CAR T¼¼Æ÷Ä¡·á ½ÃÀå ±Ô¸ð´Â 2023-2030³â 23.32%ÀÇ CAGR·Î ¼ºÀåÇÏ¿© 2030³â¿¡´Â 159¾ï 7,000¸¸ ´Þ·¯¿¡ ´ÞÇÒ °ÍÀ¸·Î ¿¹»óµË´Ï´Ù.
CAR T¼¼Æ÷Ä¡·á´Â ¸²ÇÁÁ¾, ´Ù¹ß¼º °ñ¼öÁ¾, ¹éÇ÷º´°ú °°Àº Ç÷¾×¾Ï Ä¡·á¿¡¼ ȯÀÚÀÇ ¸é¿ªÃ¼°è¸¦ ÀÌ¿ëÇØ ¾Ï¼¼Æ÷¸¦ »ç¸ê½ÃŰ´Â ÆÐ·¯´ÙÀÓÀÇ ÀüȯÀ» °¡Á®¿Ô½À´Ï´Ù. ½ÅÈï ±¹°¡ÀÇ ´Ù¹ß¼º °ñ¼öÁ¾ µî ¾Ï À¯º´·ü Áõ°¡°¡ ½ÃÀåÀ» ÁÖµµÇϰí ÀÖ½À´Ï´Ù. Á¦Ç° ½ÂÀΰú ÁýÁßÀûÀÎ ÀǾàǰ ÆÄÀÌÇÁ¶óÀÎÀÇ ÇüÅ·Π±ÔÁ¦ ´ç±¹ÀÇ Áö¿øÀÌ °ÈµÇ°í ÀÖ´Â °Íµµ ÀÌ »ê¾÷À» ´õ¿í °È½Ã۰í ÀÖ½À´Ï´Ù. ¿¹¸¦ µé¾î ¹Ì±¹ ±¹¸³ÀÇÇеµ¼°üÀÌ 2023³â 4¿ù¿¡ ¹ßÇ¥ÇÑ ÀÚ·á¿¡ µû¸£¸é CAR T¼¼Æ÷¿Í °ü·ÃµÈ ¾à 310°ÇÀÇ ¿¬±¸°¡ ¼¼°è¿¡¼ Ãʱâ 1»ó, 1»ó, 2»ó ´Ü°è¿¡ °ÉÃÄ ÁøÇàµÇ°í ÀÖ½À´Ï´Ù.
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COVID-19 ÆÒµ¥¹ÍÀ¸·Î ÀÎÇØ ȯÀÚ¿¡°Ô CAR T¼¼Æ÷Ä¡·á¸¦ ½ÃÇàÇÏ´Â °ÍÀÌ ¾î·Á¿öÁ³°í, ƯÈ÷ Àü¿°º´ Ãʱ⿡´Â ¸¹Àº º´¿ø ¹× Áø·á¼Ò°¡ COVID-19 ȯÀÚ·Î ³ÑÃijµ½À´Ï´Ù. ¸¹Àº º´¿øÀº COVID-19 ȯÀÚ¸¦ À§ÇÑ ÀÚ¿øÀ» È®º¸Çϱâ À§ÇØ CAR T¼¼Æ÷Ä¡·á¸¦ Æ÷ÇÔÇÑ ¼±ÅÃÀû Ä¡·á¸¦ ¿¬±âÇϰųª Áß´ÜÇØ¾ß Çß½À´Ï´Ù. ¶ÇÇÑ CAR T¼¼Æ÷Ä¡·á´Â ¹ß¿, ÀúÇ÷¾Ð, COVID-19 Áõ»óÀ» ¸ð¹æÇÑ Àå±â ¼Õ»óÀ» À¯¹ßÇÒ ¼ö ÀÖ´Â »çÀÌÅäÄ«ÀÎ ¹æÃâ ÁõÈıº(CRS)°ú °°Àº ½É°¢ÇÑ ºÎÀÛ¿ëÀ» À¯¹ßÇÒ ¼ö ÀÖÀ¸¹Ç·Î Ä¡·á»óÀÇ ¹®Á¦°¡ ÀÖ½À´Ï´Ù.
¶ÇÇÑ °³¹ßµµ»ó±¹¿¡ µîÀåÇÑ º´¿ø°ú ¾Ï Ä¡·á ¼¾ÅÍ´Â CAR T ¼¼Æ÷¸¦ µµÀÔÇϰí ÀÖ½À´Ï´Ù. ÀÌ ¼¾Å͵éÀº ºñ¿ë°ú ½Ã°£ È¿À²ÀûÀÎ ¾Ï Ä¡·á°¡ ½ÃÀåÀÇ Àü¹ÝÀûÀÎ ¼ºÀåÀ» °¡´ÉÇÏ°Ô ÇÏ´Â °ÍÀ¸·Î ¹øÃ¢Çϰí ÀÖ½À´Ï´Ù. ¿¹¸¦ µé¾î 2022³â 8¿ù ¸ß½ÃÄÚÀÇ ¾Ï Ä¡·á ¼¾ÅÍÀÎ Immunotherapy Institute´Â ¹Ì±¹°ú ij³ª´ÙÀÇ È¯Àڵ鿡°Ô CAR T¼¼Æ÷¸¦ Á¦°øÇÏ´Â »ç¾÷À» ½ÃÀÛÇß½À´Ï´Ù. ¸¶Âù°¡Áö·Î À̽º¶ó¿¤¿¡¼´Â ¸ðµç °úÁ¤À» ÀÚüÀûÀ¸·Î ÁøÇàÇϱ⠶§¹®¿¡ ¾à 10ÀÏ ¸¸¿¡ Ä¡·á¸¦ ¿Ï·áÇÏ¿© ºñ¿ëÀ» Å©°Ô Àý°¨ÇÒ ¼ö ÀÖ½À´Ï´Ù.
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CAR T¼¼Æ÷Ä¡·á ½ÃÀå º¸°í¼ ÇÏÀ̶óÀÌÆ®
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- 2022³â Áúȯº° ÀûÀÀÁõ¿¡¼´Â ¸²ÇÁÁ¾ÀÌ 57.15%·Î °¡Àå Å« Á¡À¯À²À» Â÷ÁöÇß½À´Ï´Ù. ÀÌ ºÐ¾ßÀÇ ³ôÀº ½ÃÀå ħÅõÀ²Àº ¼¼°è¿¡¼ ÀÌ ÁúȯÀÇ ³ôÀº À¯º´·ü¿¡ ±âÀÎÇÕ´Ï´Ù. ¶ÇÇÑ CD-19 Ç׿ø Á¦°Å¿¡ ´ëÇÑ ½ÃÀå ±â¾÷ÀÇ °·ÂÇÑ Á¦Ç° ÁýÁßµµ ¼ºÀåÀ» °¡¼ÓÇϰí ÀÖ½À´Ï´Ù.
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- ºÏ¹Ì´Â 2022³â 66.70%ÀÇ Á¡À¯À²À» Â÷ÁöÇÏ¸ç ½ÃÀå¿¡¼ ¾ÐµµÀûÀÎ À§Ä¡¸¦ Â÷ÁöÇß½À´Ï´Ù. ÀÌ·¯ÇÑ ³ôÀº Á¡À¯À²ÀÇ ÁÖ¿ä ÀÌÀ¯´Â ºü¸¥ ½ÂÀΰú źźÇÑ ÀÇ·á º¸Çè Àû¿ëÀ¸·Î ÀÎÇØ ȯÀÚ ¼ö°¡ ¸¹°í, ÀϹÝÀûÀÌ°í º¹ÀâÇÑ ÀÇ·á ¼ºñ½º¿¡ ´ëÇÑ Àü¹ÝÀûÀÎ Á¢±Ù¼ºÀÌ ³ô±â ¶§¹®ÀÎ °ÍÀ¸·Î º¸ÀÔ´Ï´Ù.
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- Á¦Ç° º¯µ¿ ºÐ¼®°ú ½ÃÀå Á¡À¯À², 2022³â°ú 2030³â
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- Abecma(idecabtagene vicleucel)
- ¼¼°èÀÇ Abecma(idecabtagene vicleucel) ½ÃÀå, 2018-2030³â(100¸¸ ´Þ·¯)
- Breyanzi(lisocabtagene maraleucel)
- ¼¼°èÀÇ Breyanzi(lisocabtagene maraleucel) ½ÃÀå, 2018-2030³â(100¸¸ ´Þ·¯)
- Carvykti(ciltacabtagene autoleucel)
- ¼¼°èÀÇ Carvykti(ciltacabtagene autoleucel) ½ÃÀå, 2018-2030(100¸¸ ´Þ·¯)
- Kymriah(tisagenlecleucel)
- ¼¼°èÀÇ Kymriah(tisagenlecleucel) ½ÃÀå, 2018-2030³â(100¸¸ ´Þ·¯)
- Tecartus(brexucabtagene autoleucel)
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- Yescarta(axicabtagene ciloleucel)
- ¼¼°èÀÇ Yescarta(axicabtagene ciloleucel) ½ÃÀå, 2018-2030(100¸¸ ´Þ·¯)
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- ¼¼°èÀÇ ±âŸ ½ÃÀå, 2018-2030³â(100¸¸ ´Þ·¯)
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- Bristol-Myers Squibb Company
- Novartis AG
- Gilead Sciences Inc
- Bluebird Bio Inc
- Johnson &Johnson Services Inc
- Merck &Co.
- Sorrento Therapeutics Inc
- Sangamo Therapeutics
- GSK Plc.
- JW Therapeutics(Shanghai) Co., Ltd.
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CAR T-cell Therapy Market Growth & Trends
The global CAR T-cell therapy market size is expected to reach USD 15.97 billion by 2030, expanding at 23.32% CAGR from 2023 to 2030, according to a new report by Grand View Research, Inc. CAR T-cell therapy presents a paradigm shift in the treatment of blood cancers such as lymphoma, multiple myeloma, and leukemia by utilizing the patient's immune system to terminate cancer cells. The rising prevalence of cancer types such as multiple myeloma in developing countries is driving the market. Rampant regulatory support in the form of product approvals and an intensive product pipeline of drugs further strengthens the industry. For instance, as per the U.S. National Library of Medicine April 2023, around 310 studies pertinent to CAR T-cells are being conducted across early phase I, phase I, and phase II in various parts of the world.
Various players are entering into strategic partnerships along with geographic expansion to necessitate therapy coverage across the world. Thereby, companies are adopting strategies to increase the geographical footprint in countries without access to potential cures or treatments for blood cancers. For instance, on August 31, 2022, Kite, a medical company operating under Gilead announced the expansion of CAR T-cell therapy in regions of Saudi Arabia, Brazil, and Singapore. The company reported an occurrence of 1000 or higher cases of non-Hodgkin lymphoma (NHL) in Singapore, while around 1700 cases of the disease are diagnosed in Saudi Arabia. Similarly, in Brazil, around 12000 cases of NHL are found each year.
The COVID-19 pandemic has made it difficult to administer CAR T-cell therapy to patients, particularly in the early stages of the pandemic when many hospitals and clinics were overwhelmed with COVID-19 patients. Many hospitals had to postpone or cancel elective procedures, including CAR T-cell therapy, to free up resources for COVID-19 patients. In addition, CAR T-cell therapy has significant side effects, including cytokine release syndrome (CRS), which can cause fever, low blood pressure, and organ damage which mimics the symptoms of COVID-19, thereby, curating problems to treat for condition.
Moreover, hospitals and cancer care centers emerging in developing countries are progressing with the adoption of CAR T-cells. These centers thrive as cost and time-efficient cancer treatments allow the market to grow holistically. For instance, in August 2022, Immunotherapy Institute, a cancer treatment center in Mexico began operations to offer CAR T-cells for American and Canadian patients. Similarly, in Israel, the therapy can be expedited in about 10 days owing to the entire process being conducted in-house, with notable cost reductions.
The lack of skilled professionals in emerging nations coupled with the high cost associated with the therapy remain challenges to market growth. However, rising awareness and increasing approvals for technologically advanced CAR T-cell therapy are anticipated to mitigate these challenges and contribute to market growth over the forecast period. According to Cancer Treatment Centers of America, six CAR T-cell therapies were approved by U.S. FDA for the treatment of blood cancers as of 2023.
CAR T-cell Therapy Market Report Highlights
- By product, the Yescarta (axicabtagene ciloleucel) segment dominated the market with a share of 43.76% in 2022. The high usage of Yescarta can be attributed to strong performance and improved survivability in adults suffering from relapsed B-cell large lymphoma
- Lymphoma accounted for the largest share of 57.15% in the disease indication segment in 2022. The high penetration of the market segment owes itself to the significant prevalence of the condition across the world. Additionally, the strong product focus by market players to eliminate the CD-19 antigen drives growth
- By end-use, the hospital segment captured a majority share of 56.26% in 2022 due to the robust presence of fiscal and operational resources. Additionally, in-house labs for hospitals expedite the process faster, helping to gain a strong share
- North America has shown a dominant position in the market with a 66.70% share in 2022. The primary reason for a sizable share can be attributed to the patient volume and overall access to general and complex healthcare, with speedy approvals and robust medical insurance coverage
Table of Contents
Chapter 1. Methodology and Scope
- 1.1. Market Segmentation and Scope
- 1.1.1. Market definitions
- 1.1.1.1. Product segment
- 1.1.1.2. Disease indication segment
- 1.1.1.3. End-use segment
- 1.2. Information Procurement
- 1.2.1. Market formulation & data visualization
- 1.2.2. Data validation & publishing
- 1.3. Research Assumptions
- 1.4. Research Methodology
- 1.4.1. Purchased database
- 1.4.2. GVR's internal database
- 1.4.3. Secondary sources
- 1.4.4. Primary research
- 1.4.5. Details of primary research
- 1.5. Information or Data Analysis
- 1.5.1. Data analysis models
- 1.6. Market Formulation & Validation
- 1.7. Model Details
- 1.7.1. Commodity flow analysis
- 1.7.1.1. Approach 1: Commodity flow approach
- 1.8. List of Secondary Sources
- 1.9. Global Market: CAGR CalculationObjectives
Chapter 2. Executive Summary
- 2.1. Market Snapshot
- 2.2. Segment Snapshot
- 2.3. Competitive Landscape Snapshot
Chapter 3. Market Variables, Trends, & Scope
- 3.1. Market Lineage Outlook
- 3.1.1. Parent Market Outlook
- 3.1.2. Related/Ancillary Market Outlook
- 3.2. Market Trends and Outlook
- 3.3. Market Dynamics
- 3.3.1. Market Driver Analysis
- 3.3.1.1. Growing cases of Cancer Malignancies across population
- 3.3.1.2. Targeted treatment approach mitigates relapsed or refracted blood cancer cases.
- 3.3.1.3. Robust product pipeline with regulatory approvals across geographies.
- 3.3.2. Market Restraint Analysis
- 3.3.2.1. High drug cost impedes the market growth
- 3.3.2.2. Side-effects of CAR T-cell therapy
- 3.3.2.3. Complex Manufacturing and Supply Chain
- 3.4. Business Environment Analysis
- 3.4.1. SWOT Analysis; By Factor (Political & Legal, Economic And Technological)
- 3.4.2. Porter's Five Forces Analysis
- 3.4.3. COVID-19 Impact Analysis
Chapter 4. CAR T-cell Therapy Market: Product Estimates & Trend Analysis
- 4.1. Product Movement Analysis & Market Share, 2022 & 2030
- 4.2. CAR T-cell Therapy Market Estimates & Forecast, By Product (USD Million)
- 4.3. Abecma (idecabtagene vicleucel)
- 4.3.1. Global Abecma (idecabtagene vicleucel) Market, 2018 - 2030 (USD Million)
- 4.4. Breyanzi (lisocabtagene maraleucel)
- 4.4.1. Global Breyanzi (lisocabtagene maraleucel) Market, 2018 - 2030 (USD Million)
- 4.5. Carvykti (ciltacabtagene autoleucel)
- 4.5.1. Global Carvykti (ciltacabtagene autoleucel) Market, 2018 - 2030 (USD Million)
- 4.6. Kymriah (tisagenlecleucel)
- 4.6.1. Global Kymriah (tisagenlecleucel) Market, 2018 - 2030 (USD Million)
- 4.7. Tecartus (brexucabtagene autoleucel)
- 4.7.1. Global Tecartus (brexucabtagene autoleucel) Market, 2018 - 2030 (USD Million)
- 4.8. Yescarta (axicabtagene ciloleucel)
- 4.8.1. Global Yescarta (axicabtagene ciloleucel) Market, 2018 - 2030 (USD Million)
- 4.9. Others
- 4.9.1. Global Others Market, 2018 - 2030 (USD Million)
Chapter 5. CAR T-cell Therapy Market: Disease Indication Estimates & Trend Analysis
- 5.1. Disease Indication Movement Analysis & Market Share, 2022& 2030
- 5.2. CAR T-cell Therapy Market Estimates & Forecast, By Disease Indication (USD Million)
- 5.3. Leukemia
- 5.3.1. Global Leukemia Market, 2018 - 2030 (USD Million)
- 5.4. Lymphoma
- 5.4.1. Global Lymphoma Market, 2018 - 2030 (USD Million)
- 5.5. Multiple Myeloma
- 5.5.1. Global Multiple Myeloma Market, 2018 - 2030 (USD Million)
Chapter 6. End-use Business Analysis
- 6.1. End-use Movement Analysis & Market Share, 2022& 2030
- 6.2. CAR T-cell Therapy Market Estimates & Forecast, By End-use (USD Million)
- 6.3. Hospitals
- 6.3.1. Hospitals Market, 2018 - 2030 (USD Million)
- 6.4. Cancer Treatment Centers
- 6.4.1. Cancer Treatment Market, 2018 - 2030 (USD Million)
Chapter 7. Regional Business Analysis
- 7.1. CAR T-cell Therapy Market: Region Outlook
- 7.2. North America
- 7.2.1. North America CAR T-cell Therapy market estimates and forecast, 2018 - 2030 (USD Million)
- 7.2.2. The U.S.
- 7.2.2.1. Key Country Dynamics
- 7.2.2.2. Competitive Scenario
- 7.2.2.3. Regulatory Framework
- 7.2.2.4. Disease Prevalence
- 7.2.2.5. U.S. CAR T-cell therapy market estimates and forecast, 2018 - 2030 (USD Million)
- 7.2.3. Canada
- 7.2.3.1. Key Country Dynamics
- 7.2.3.2. Competitive Scenario
- 7.2.3.3. Regulatory Framework
- 7.2.3.4. Disease Prevalence
- 7.2.3.5. Canada CAR T-cell therapy market estimates and forecast, 2018 - 2030 (USD Million)
- 7.3. Europe
- 7.3.1. Europe CAR T-cell Therapy market estimates and forecast, 2018 - 2030 (USD Million)
- 7.3.2. Germany
- 7.3.2.1. Key Country Dynamics
- 7.3.2.2. Competitive Scenario
- 7.3.2.3. Regulatory Framework
- 7.3.2.4. Disease Prevalence
- 7.3.2.5. Germany CAR T-cell therapy market estimates and forecast, 2018 - 2030 (USD Million)
- 7.3.3. UK
- 7.3.3.1. Key Country Dynamics
- 7.3.3.2. Competitive Scenario
- 7.3.3.3. Regulatory Framework
- 7.3.3.4. Disease Prevalence
- 7.3.3.5. UK CAR T-cell therapy market estimates and forecast, 2018 - 2030 (USD Million)
- 7.4. Asia Pacific
- 7.4.1. Asia Pacific CAR T-cell Therapy market estimates and forecast, 2018 - 2030 (USD Million)
- 7.4.2. Japan
- 7.4.2.1. Key Country Dynamics
- 7.4.2.2. Competitive Scenario
- 7.4.2.3. Regulatory Framework
- 7.4.2.4. Disease Prevalence
- 7.4.2.5. Japan CAR T-cell therapy market estimates and forecast, 2018 - 2030 (USD Million)
- 7.4.3. China
- 7.4.3.1. Key Country Dynamics
- 7.4.3.2. Competitive Scenario
- 7.4.3.3. Regulatory Framework
- 7.4.3.4. Disease Prevalence
- 7.4.3.5. China CAR T-cell therapy market estimates and forecast, 2018 - 2030 (USD Million)
- 7.5. Rest of World
- 7.5.1. Rest of World CAR T-cell Therapy market estimates and forecast, 2018 - 2030 (USD Million)
Chapter 8. Competitive Landscape
- 8.1. Company Categorization
- 8.2. Strategy Mapping
- 8.3. Company Profiles/Listing
- 8.3.1. Bristol-Myers Squibb Company
- 8.3.1.1. Overview
- 8.3.1.2. Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
- 8.3.1.3. Product Benchmarking
- 8.3.1.4. Strategic Initiatives
- 8.3.2. Novartis AG
- 8.3.2.1. Overview
- 8.3.2.2. Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
- 8.3.2.3. Product Benchmarking
- 8.3.2.4. Strategic Initiatives
- 8.3.2.5. Overview
- 8.3.2.6. Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
- 8.3.2.7. Product Benchmarking
- 8.3.2.8. Strategic Initiatives
- 8.3.3. Gilead Sciences Inc
- 8.3.3.1. Overview
- 8.3.3.2. Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
- 8.3.3.3. Product Benchmarking
- 8.3.3.4. Strategic Initiatives
- 8.3.4. Bluebird Bio Inc
- 8.3.4.1. Overview
- 8.3.4.2. Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
- 8.3.4.3. Product Benchmarking
- 8.3.4.4. Strategic Initiatives
- 8.3.5. Johnson & Johnson Services Inc
- 8.3.5.1. Overview
- 8.3.5.2. Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
- 8.3.5.3. Product Benchmarking
- 8.3.5.4. Strategic Initiatives
- 8.3.6. Merck & Co.
- 8.3.6.1. Overview
- 8.3.6.2. Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
- 8.3.6.3. Product Benchmarking
- 8.3.6.4. Strategic Initiatives
- 8.3.7. Sorrento Therapeutics Inc
- 8.3.7.1. Overview
- 8.3.7.2. Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
- 8.3.7.3. Product Benchmarking
- 8.3.7.4. Strategic Initiatives
- 8.3.8. Sangamo Therapeutics
- 8.3.8.1. Overview
- 8.3.8.2. Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
- 8.3.8.3. Product Benchmarking
- 8.3.8.4. Strategic Initiatives
- 8.3.9. GSK Plc.
- 8.3.9.1. Overview
- 8.3.9.2. Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
- 8.3.9.3. Product Benchmarking
- 8.3.9.4. Strategic Initiatives
- 8.3.10. JW Therapeutics (Shanghai) Co., Ltd.
- 8.3.10.1. Overview
- 8.3.10.2. Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
- 8.3.10.3. Product Benchmarking
- 8.3.10.4. Strategic Initiatives
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