DNA 복구 알킬화제 시장 보고서(2026년)
Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Global Market Report 2026
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리서치사 : The Business Research Company
발행일 : On Demand Report
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한글목차

데옥시리보핵산(DNA) 복구 알킬화제 시장 규모는 최근 현저한 성장을 보이고 있습니다. 2025년 37억 달러에서 2026년에는 40억 달러로, CAGR 8.1%로 확대될 전망입니다. 지난 수년간의 성장 요인으로는 알킬화제 공급 제한, 기존 화학요법에 대한 의존도, 암 환자 수 증가, 병원 기반 종양 치료의 확대, 표준 임상 프로토콜의 채택 등을 들 수 있습니다.

데옥시리보핵산(DNA) 복구 알킬화제 시장 규모는 향후 몇 년간 강력한 성장이 전망됩니다. 2030년에는 54억 5,000만 달러에 달하고, CAGR은 8.0%가 될 전망입니다. 예측 기간 동안 성장 요인으로는 신규 질소 겨자 및 니트로소우레아 계열 약물 개발, 맞춤형 암 치료 확대, 표적 알킬화제에 대한 R&D 투자 증가, 유전체 검사 및 정밀의료와의 통합, 최적화된 치료 요법에 대한 인식과 채택 확대 등을 꼽았습니다. 예측 기간 동안 주요 동향으로는 암 치료에서 DNA 복구 알킬화제의 채택 증가, 신규 알킬화 화합물 연구 확대, 임상시험 및 R&D 활동 확대, 맞춤 의료 및 표적 치료의 적용 확대, 안전성, 용량 최적화 및 규제 준수에 대한 관심 증가 등을 들 수 있습니다.

전 세계적으로 암 환자 증가 추세가 두드러지고 있으며, 향후 몇 년 동안 DNA 복구 알킬화제 시장의 성장을 견인할 것으로 예상됩니다. 암은 특정 세포가 통제할 수 없을 정도로 증식하여 주변 조직을 침범하거나 신체의 다른 부위로 전이되는 질환입니다. 전 세계 암 환자 수의 증가는 주로 고령화 사회의 진전에 기인하며, 암 발병 위험은 나이가 들어감에 따라 현저하게 증가합니다. DNA 복구 알킬화제는 빠르게 분열하는 종양세포의 DNA를 손상시켜 세포의 복제 능력을 억제함으로써 암 치료에 사용됩니다. 이 DNA 손상은 세포 사멸 또는 증식 정지를 일으켜 종양의 진행 억제에 기여합니다. 예를 들어, 2024년 2월 스위스에 본부를 둔 세계보건기구(WHO)가 발표한 자료에 따르면, 2022년에는 약 2,000만 건의 신규 암이 보고될 것으로 예상되며, 2050년에는 이 숫자가 3,500만 건을 넘어설 것으로 예측됩니다. 따라서 전 세계적으로 증가하는 암 부담은 DNA 복구 알킬화제 시장의 성장에 기여하고 있습니다.

데옥시리보핵산(DNA) 복구 알킬화제 시장에서 활동하는 주요 기업들은 치료 정확도를 높이고 표적 외 독성을 최소화하며 혈액암 치료 성적을 높이기 위해 에폭시드 형성 알킬화제 등 첨단 치료법 개발에 주력하고 있습니다. 에폭시드 형성 알킬화제는 체내에서 대사되어 반응성이 높은 에폭시드 중간체로 전환되는 프로드러그이며, DNA를 알킬화 및 가교시킴으로써 기존의 이중기능성 알킬화제에 비해 보다 제어된 활성화 메커니즘을 제공합니다. 예를 들어, 캐나다에 본사를 둔 제약회사 메덱스 파마슈티컬스(Medexus Pharmaceuticals)는 지난 1월 미국 식품의약국(FDA)으로부터 성인 및 1세 이상 소아 환자의 급성 골수성 백혈병 또는 골수이형성증후군에 대한 동종 조혈모세포 이식의 전처치 요법으로서 플루달라빈과의 병용요법으로 사용되는 알킬화제 '그라펙스(트레오설판)'를 승인 받았습니다. 트레오설판은 정맥주사용 동결건조 분말로 공급되며, 생체 내에서는 DNA를 가교하는 모노-디에폭시드 대사산물로 전환됩니다. 우수한 약동학, 부설판 계열 요법 대비 낮은 장기 독성, 임상 3상 시험에서 입증된 생존율 향상 등의 장점을 바탕으로 GRAFAPEX는 이식 치료 환경에서 보다 정교한 DNA 손상 치료제로의 시장 전환을 강조하고 있습니다.

목차

제1장 주요 요약

제2장 시장 특징

제3장 시장 공급망 분석

제4장 세계 시장 동향과 전략

제5장 최종 이용 산업 시장 분석

제6장 시장 : 금리, 인플레이션, 지정학, 무역 전쟁과 관세의 영향, 관세 전쟁과 무역 보호주의가 공급망에 미치는 영향, 코로나가 시장에 미치는 영향을 포함한 거시경제 시나리오

제7장 세계의 전략 분석 프레임워크, 현재 시장 규모, 시장 비교 및 성장률 분석

제8장 시장에서 세계의 총 잠재 시장 규모(TAM)

제9장 시장 세분화

제10장 지역별, 국가별 분석

제11장 아시아태평양 시장

제12장 중국 시장

제13장 인도 시장

제14장 일본 시장

제15장 호주 시장

제16장 인도네시아 시장

제17장 한국 시장

제18장 대만 시장

제19장 동남아시아 시장

제20장 서유럽 시장

제21장 영국 시장

제22장 독일 시장

제23장 프랑스 시장

제24장 이탈리아 시장

제25장 스페인 시장

제26장 동유럽 시장

제27장 러시아 시장

제28장 북미 시장

제29장 미국 시장

제30장 캐나다 시장

제31장 남미 시장

제32장 브라질 시장

제33장 중동 시장

제34장 아프리카 시장

제35장 시장 규제 상황과 투자 환경

제36장 경쟁 구도와 기업 개요

제37장 기타 주요 기업과 혁신적 기업

제38장 세계의 시장 경쟁 벤치마킹과 대시보드

제39장 주요 인수합병

제40장 시장 잠재력이 높은 국가, 부문, 전략

제41장 부록

KSM
영문 목차

영문목차

A deoxyribonucleic acid (DNA) repair alkylating agent is a type of chemotherapy drug that introduces alkyl groups into DNA molecules, resulting in DNA damage that disrupts the ability of cancer cells to replicate and survive. These agents form covalent bonds with DNA, leading to cross-linking or incorrect base pairing, which can cause cell cycle arrest or apoptosis if the damage cannot be repaired.

The main product types of deoxyribonucleic acid (DNA) repair alkylating agents include nitrogen mustards, nitrosoureas, alkyl sulfonates, triazines, and others. Nitrogen mustards are strong bifunctional alkylating agents used in cancer therapy and are also associated with adverse effects such as skin injury, inflammation, and potential carcinogenic risks. These agents are used in various applications, including cancer treatment, research and development, and other areas, and are utilized by end users such as hospitals, research institutes, pharmaceutical companies, and others.

Tariffs have affected the DNA repair alkylating agent market by increasing the cost of imported active pharmaceutical ingredients (APIs) and raw materials used in drug synthesis. Segments such as nitrogen mustards, nitrosoureas, and triazines are particularly impacted, with Asia-Pacific regions including China and India experiencing higher import duties. This has led to increased production costs and potential delays in drug availability. Positively, tariffs have encouraged local manufacturing initiatives, promoted domestic API production, and spurred investment in supply chain diversification.

The deoxyribonucleic acid (dna) repair alkylating agent market research report is one of a series of new reports from The Business Research Company that provides deoxyribonucleic acid (dna) repair alkylating agent market statistics, including deoxyribonucleic acid (dna) repair alkylating agent industry global market size, regional shares, competitors with a deoxyribonucleic acid (dna) repair alkylating agent market share, detailed deoxyribonucleic acid (dna) repair alkylating agent market segments, market trends and opportunities, and any further data you may need to thrive in the deoxyribonucleic acid (dna) repair alkylating agent industry. This deoxyribonucleic acid (dna) repair alkylating agent market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The deoxyribonucleic acid (dna) repair alkylating agent market size has grown strongly in recent years. It will grow from $3.7 billion in 2025 to $4 billion in 2026 at a compound annual growth rate (CAGR) of 8.1%. The growth in the historic period can be attributed to limited availability of alkylating agents, reliance on conventional chemotherapy regimens, growing cancer patient population, increasing hospital-based oncology treatments, adoption of standard clinical protocols.

The deoxyribonucleic acid (dna) repair alkylating agent market size is expected to see strong growth in the next few years. It will grow to $5.45 billion in 2030 at a compound annual growth rate (CAGR) of 8.0%. The growth in the forecast period can be attributed to development of novel nitrogen mustards and nitrosoureas, expansion of personalized oncology therapies, increasing r&d investment in targeted alkylating agents, integration with genomic testing and precision medicine, rising awareness and adoption of optimized treatment regimens. Major trends in the forecast period include rising adoption of dna repair alkylating agents in cancer therapy, increasing research on novel alkylating compounds, expansion of clinical trials and r&d activities, growing personalized medicine and targeted therapy applications, enhanced focus on safety, dosage optimization and regulatory compliance.

The increasing prevalence of cancer cases globally is expected to drive the growth of the DNA repair alkylating agent market in the coming years. Cancer is a disease in which certain cells grow uncontrollably and can invade nearby tissues or spread to other parts of the body. The rise in cancer cases worldwide is largely attributed to the growing aging population, as the risk of developing cancer increases significantly with age. DNA repair alkylating agents are used in cancer treatment by damaging the DNA of rapidly dividing tumor cells, thereby inhibiting their ability to replicate. This DNA damage results in cell death or growth arrest, helping to suppress tumor progression. For instance, in February 2024, according to the World Health Organization, a Switzerland-based healthcare organization, an estimated 20 million new cancer cases were reported in 2022, with projections indicating this number could exceed 35 million by 2050. Therefore, the rising global burden of cancer is contributing to the growth of the DNA repair alkylating agent market.

Major players operating in the deoxyribonucleic acid (DNA) repair alkylating agent market are concentrating on the development of advanced therapies, such as epoxide-forming alkylators, to improve treatment precision, minimize off-target toxicity, and enhance outcomes in hematologic cancers. Epoxide-forming alkylators are prodrugs that are metabolized in the body into highly reactive epoxide intermediates, which alkylate and cross-link DNA, providing a more controlled activation mechanism compared to conventional bifunctional alkylating agents. For instance, in January 2025, Medexus Pharmaceuticals, a Canada-based pharmaceutical company, received approval from the US Food and Drug Administration for GRAFAPEX (treosulfan), an alkylating agent used in combination with fludarabine as a conditioning regimen for allogeneic hematopoietic stem cell transplantation in adult and pediatric patients aged one year and older with acute myeloid leukemia or myelodysplastic syndrome. Treosulfan is supplied as a lyophilized powder for intravenous infusion and is converted in vivo into mono- and diepoxide metabolites that cross-link DNA. Supported by favorable pharmacokinetics, lower long-term toxicity compared with busulfan-based regimens, and demonstrated survival benefits in a Phase III trial, GRAFAPEX highlights the market's transition toward more refined DNA-damaging therapies in transplant settings.

In June 2024, Dr. Reddy's Laboratories USA, a US-based pharmaceutical manufacturer involved in the development and production of anticancer drugs including alkylating agents, partnered with Ingenus Pharmaceuticals LLC to expand access to quality cancer treatments. This collaboration aims to strengthen the availability of cyclophosphamide injection in the US market by combining Ingenus's manufacturing capabilities with Dr. Reddy's extensive distribution network. Ingenus Pharmaceuticals LLC is a US-based producer of cost-effective generic medicines for patients.

Major companies operating in the deoxyribonucleic acid (dna) repair alkylating agent market are Bristol-Myers Squibb Company, Teva Pharmaceutical Industries Limited, Fresenius Kabi, Intas Pharmaceuticals, Dr. Reddy's Laboratories, Aurobindo Pharma, Hikma Pharmaceuticals, Natco Pharma Ltd, Medac GmbH, Emcure Pharmaceuticals, Jiangsu Hengrui Pharmaceuticals Co. Ltd.

North America was the largest region in the deoxyribonucleic acid (DNA) repair alkylating agent market in 2025. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the deoxyribonucleic acid (dna) repair alkylating agent market report are Asia-Pacific, South East Asia, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

The countries covered in the deoxyribonucleic acid (dna) repair alkylating agent market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Taiwan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

The deoxyribonucleic acid (DNA) repair alkylating agent market consists of sales of ethylenimines and methylmelamines, hydrazines, aziridines, and procarbazine. Values in this market are 'factory gate' values, that is, the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market Global Report 2026 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.

This report focuses deoxyribonucleic acid (dna) repair alkylating agent market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.

Reasons to Purchase

Where is the largest and fastest growing market for deoxyribonucleic acid (dna) repair alkylating agent ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The deoxyribonucleic acid (dna) repair alkylating agent market global report from the Business Research Company answers all these questions and many more.

The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, total addressable market (TAM), market attractiveness score (MAS), competitive landscape, market shares, company scoring matrix, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.

Scope

Added Benefits available all on all list-price licence purchases, to be claimed at time of purchase. Customisations within report scope and limited to 20% of content and consultant support time limited to 8 hours.

Table of Contents

1. Executive Summary

2. Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market Characteristics

3. Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market Supply Chain Analysis

4. Global Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market Trends And Strategies

5. Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market Analysis Of End Use Industries

6. Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market - Macro Economic Scenario Including The Impact Of Interest Rates, Inflation, Geopolitics, Trade Wars and Tariffs, Supply Chain Impact from Tariff War & Trade Protectionism, And Covid And Recovery On The Market

7. Global Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Strategic Analysis Framework, Current Market Size, Market Comparisons And Growth Rate Analysis

8. Global Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Total Addressable Market (TAM) Analysis for the Market

9. Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market Segmentation

10. Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market Regional And Country Analysis

11. Asia-Pacific Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market

12. China Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market

13. India Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market

14. Japan Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market

15. Australia Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market

16. Indonesia Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market

17. South Korea Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market

18. Taiwan Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market

19. South East Asia Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market

20. Western Europe Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market

21. UK Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market

22. Germany Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market

23. France Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market

24. Italy Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market

25. Spain Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market

26. Eastern Europe Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market

27. Russia Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market

28. North America Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market

29. USA Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market

30. Canada Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market

31. South America Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market

32. Brazil Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market

33. Middle East Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market

34. Africa Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market

35. Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market Regulatory and Investment Landscape

36. Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market Competitive Landscape And Company Profiles

37. Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market Other Major And Innovative Companies

38. Global Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market Competitive Benchmarking And Dashboard

39. Key Mergers And Acquisitions In The Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market

40. Deoxyribonucleic Acid (DNA) Repair Alkylating Agent Market High Potential Countries, Segments and Strategies

41. Appendix

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