사이클린 의존성 키나아제(CDK) 4/6 억제제 시장 보고서(2026년)
Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Global Market Report 2026
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한글목차

사이클린 의존성 키나아제(CDK) 4/6 억제제 시장 규모는 최근 빠르게 확대하고 있습니다. 2025년 148억 3,000만 달러에서 2026년에는 175억 9,000만 달러로, CAGR 18.6%로 성장할 것으로 예상됩니다. 지난 수년간의 성장에는 FDA의 파보시클립 승인, HR 양성 HER2 음성 유방암 발생률 증가, 선진국의 표적 치료제 도입, CDK4/6 억제제 임상시험 증가, 제약사 간 종양학 연구 제휴 등이 주요 요인으로 꼽히고 있습니다.

사이클린 의존성 키나아제(CDK) 4/6 억제제 시장 규모는 향후 몇 년간 급속한 성장이 전망됩니다. 2030년에는 357억 1,000만 달러에 달하고, CAGR은 19.4%로 예측됩니다. 예측 기간 동안 성장 요인으로는 유방암을 앓고 있는 고령 인구의 증가, 표적 치료의 이점에 대한 인식 증가, 신흥 시장의 종양 의료 인프라 확대, 환자 모니터링을 위한 디지털 헬스 솔루션의 통합, 차세대 CDK4/6 억제제 연구개발(R&D)의 증가 등을 꼽을 수 있습니다. 예측 기간의 주요 동향으로는 맞춤 치료 요법, 병용요법 접근법, 경구용 CDK4/6 억제제, 신흥 종양학 시장 확대, 리얼월드 데이터(RWE), 환자 모니터링 등을 꼽을 수 있습니다.

유방암 치료제 연구개발에 대한 투자 증가는 향후 몇 년간 사이클린 의존성 키나아제(CDK) 4/6 억제제 시장의 성장을 견인할 것으로 예상됩니다. 유방암은 유방 내 비정상 세포가 통제할 수 없을 정도로 증식하여 종양을 형성하는 질환입니다. 보다 효과적이고 개인화된 치료법에 대한 수요가 증가함에 따라 유방암 연구개발에 대한 투자가 증가하고 있습니다. CDK4/6 억제제는 암세포의 증식을 촉진하는 단백질을 억제하여 종양의 진행을 늦추거나 멈추게 하는 작용이 있어 유방암 치료에 사용됩니다. 예를 들어, 2025년 7월 미국 정부 기관인 국립암연구소(NCI)는 2023 회계연도에 유방암 연구 예산으로 약 5억 4,200만 달러(한화 약 6,000억 원)를 배정했다고 보고했습니다. 따라서 유방암 연구개발에 대한 투자 증가가 사이클린 의존성 키나아제(CDK) 4/6 억제제 시장의 성장을 촉진하고 있습니다.

사이클린 의존성 키나아제(CDK) 4/6 억제제 시장의 주요 기업들은 치료 시 독성을 감소시키는 AI 기반 툴 등 기술적으로 진보된 솔루션 개발에 집중하여 업계의 중요한 니즈를 충족시키고 있습니다. 호르몬 민감성 유방암 치료를 위한 AI 도구는 치료의 개인화를 통한 독성 최소화, 부작용 예측, 적절한 시기의 개입 지원을 통해 궁극적으로 치료의 안전성과 유효성을 향상시킬 수 있습니다. 예를 들어, 2024년 5월 스페인에 본사를 둔 혁신적인 유방암 연구 기업 SOLTI는 호르몬 요법을 받는 유방암 환자의 치료에서 독성을 줄이기 위해 설계된 AI 기반 도구를 발표했습니다. 이 도구는 유방 조직 샘플의 암성 및 비암성 요소를 모두 분석하여 치료 결과를 보다 정확하게 예측하고, 적극적인 화학요법이 필요하지 않은 환자를 식별할 수 있습니다. 이 AI 도구는 불필요한 부작용을 최소화하고 개인화된 치료 계획을 지원함으로써 환자의 삶의 질을 높이고 전반적인 치료 효과를 향상시키는 것을 목표로 하고 있습니다. 이번 개발은 진행성 ER+/HER2+ 유방암에 대한 호르몬 요법과 표적 치료제 병용요법의 이점을 밝힌 SOLTI의 PATRICIA 연구의 유망한 결과를 기반으로 하고 있습니다.

목차

제1장 주요 요약

제2장 시장 특징

제3장 시장 공급망 분석

제4장 세계 시장 동향과 전략

제5장 최종 이용 산업 시장 분석

제6장 시장 : 금리, 인플레이션, 지정학, 무역 전쟁과 관세의 영향, 관세 전쟁과 무역 보호주의가 공급망에 미치는 영향, 코로나가 시장에 미치는 영향을 포함한 거시경제 시나리오

제7장 세계의 전략 분석 프레임워크, 현재 시장 규모, 시장 비교 및 성장률 분석

제8장 시장에서 세계의 총 잠재 시장 규모(TAM)

제9장 시장 세분화

제10장 지역별, 국가별 분석

제11장 아시아태평양 시장

제12장 중국 시장

제13장 인도 시장

제14장 일본 시장

제15장 호주 시장

제16장 인도네시아 시장

제17장 한국 시장

제18장 대만 시장

제19장 동남아시아 시장

제20장 서유럽 시장

제21장 영국 시장

제22장 독일 시장

제23장 프랑스 시장

제24장 이탈리아 시장

제25장 스페인 시장

제26장 동유럽 시장

제27장 러시아 시장

제28장 북미 시장

제29장 미국 시장

제30장 캐나다 시장

제31장 남미 시장

제32장 브라질 시장

제33장 중동 시장

제34장 아프리카 시장

제35장 시장 규제 상황과 투자 환경

제36장 경쟁 구도와 기업 개요

제37장 기타 주요 기업과 혁신적 기업

제38장 세계의 시장 경쟁 벤치마킹과 대시보드

제39장 주요 인수합병

제40장 시장 잠재력이 높은 국가, 부문, 전략

제41장 부록

KSM
영문 목차

영문목차

Cyclin-dependent kinase (CDK) 4/6 inhibitor drugs are targeted therapy medications used to treat certain types of hormone receptor-positive, HER2-negative breast cancer. These drugs target specific enzymes, CDK4 and CDK6, and block signals that promote the proliferation of cancerous cells.

The main types of cyclin-dependent kinase (CDK) 4/6 inhibitor drugs include palbociclib (Ibrance), ribociclib (Kisqali), and abemaciclib (Verzenio). Palbociclib (Ibrance) is a targeted therapy developed for hormone receptor-positive (HR+) and human epidermal growth factor receptor 2-negative (HER2-) breast cancer and is also used in combination with endocrine therapy to provide an effective treatment option for patients with advanced or metastatic breast cancer. These drugs are used to treat patients including premenopausal and postmenopausal individuals, and are administered by end users such as hospitals, clinics, research laboratories, and retail pharmacies.

Tariffs have influenced the CDK4/6 inhibitor drugs market by increasing costs of imported active pharmaceutical ingredients (APIs) and raw materials, leading to higher production expenses for manufacturers. These tariffs particularly affect drug types like palbociclib, ribociclib, and abemaciclib, with regions such as North America and Europe facing more pronounced impacts due to reliance on global supply chains. While tariffs may slow pricing competitiveness, they also encourage local manufacturing investments and domestic supply chain development, potentially boosting market resilience and innovation in formulation strategies.

The cyclin-dependent kinase (cdk) 4/6 inhibitor drugs market research report is one of a series of new reports from The Business Research Company that provides cyclin-dependent kinase (cdk) 4/6 inhibitor drugs market statistics, including cyclin-dependent kinase (cdk) 4/6 inhibitor drugs industry global market size, regional shares, competitors with a cyclin-dependent kinase (cdk) 4/6 inhibitor drugs market share, detailed cyclin-dependent kinase (cdk) 4/6 inhibitor drugs market segments, market trends and opportunities, and any further data you may need to thrive in the cyclin-dependent kinase (cdk) 4/6 inhibitor drugs industry. This cyclin-dependent kinase (cdk) 4/6 inhibitor drugs market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The cyclin-dependent kinase (cdk) 4/6 inhibitor drugs market size has grown rapidly in recent years. It will grow from $14.83 billion in 2025 to $17.59 billion in 2026 at a compound annual growth rate (CAGR) of 18.6%. The growth in the historic period can be attributed to approval of palbociclib by fda, increasing incidence of hr-positive her2-negative breast cancer, adoption of targeted therapies in developed countries, rising clinical trials for cdk4/6 inhibitors, partnerships between pharma companies for oncology research.

The cyclin-dependent kinase (cdk) 4/6 inhibitor drugs market size is expected to see rapid growth in the next few years. It will grow to $35.71 billion in 2030 at a compound annual growth rate (CAGR) of 19.4%. The growth in the forecast period can be attributed to rising geriatric population with breast cancer, growing awareness of targeted therapy benefits, expansion of oncology healthcare infrastructure in emerging markets, integration of digital health solutions for patient monitoring, increased r&d in next-generation cdk4/6 inhibitors. Major trends in the forecast period include personalized treatment regimens, combination therapy approaches, oral cdk4/6 inhibitor formulations, expansion in emerging oncology markets, real-world evidence and patient monitoring.

The increasing investment in research and development for breast cancer treatment is expected to drive the growth of the cyclin-dependent kinase (CDK) 4/6 inhibitor drugs market in the coming years. Breast cancer is a disease in which abnormal cells in the breast grow uncontrollably and form tumors. Investment in breast cancer R&D is rising due to the growing demand for more effective and personalized treatment options. CDK 4/6 inhibitor drugs are used in breast cancer therapy by blocking proteins that drive cancer cell growth, helping to slow or halt tumor progression. For instance, in July 2025, the National Cancer Institute (NCI), a US-based government agency, reported allocating an estimated $542.0 million in FY 2023 specifically for breast cancer research. Therefore, rising investment in breast cancer R&D is propelling the growth of the cyclin-dependent kinase (CDK) 4/6 inhibitor drug market.

Major companies in the cyclin-dependent kinase (CDK) 4/6 inhibitor drugs market are concentrating on developing technologically advanced solutions, such as AI-based tools to reduce toxicities in treatment, addressing several critical industry needs. AI tools for hormonal breast cancer therapy help personalize treatments to minimize toxicities, predict adverse effects, and support timely interventions, ultimately improving treatment safety and effectiveness. For instance, in May 2024, SOLTI, a Spain-based innovative breast cancer research company, launched an AI-based tool designed to reduce toxicities in the treatment of hormonal breast cancer patients. This tool analyzes both cancerous and non-cancerous elements in breast tissue samples, enabling more accurate predictions of treatment outcomes and identifying patients who may not require aggressive chemotherapy. By minimizing unnecessary side effects and supporting personalized treatment plans, the AI tool aims to enhance patient quality of life and improve overall treatment efficacy. This development builds on promising results from SOLTI's PATRICIA study, which highlighted the benefits of combining hormone therapy with targeted treatments for advanced ER+/HER2+ breast cancer.

In October 2024, Genentech, a US-based biopharmaceutical R&D company, acquired the CDK inhibitor portfolio of Regor Pharmaceuticals, Inc. for $850 million. Through this acquisition, Genentech aimed to strengthen its breast cancer pipeline by adding next-generation CDK4/2 and CDK4 candidates designed to overcome resistance mechanisms to existing CDK4/6 inhibitors. Regor Pharmaceuticals is a US-based biotechnology company that develops selective and potent cyclin-dependent kinase (CDK) inhibitors, including RGT-419B (a CDK4/2 inhibitor in Phase I) and a preclinical CDK4 inhibitor (RGT-587).

Major companies operating in the cyclin-dependent kinase (cdk) 4/6 inhibitor drugs market are Pfizer Inc., Novartis AG, Eli Lilly and Company, AstraZeneca PLC, Roche Holding AG, Bristol-Myers Squibb Company, Merck & Co. Inc., Sanofi SA, Gilead Sciences Inc., Jiangsu Hengrui Medicine Co. Ltd., Innovent Biologics Inc., OncoMed Pharmaceuticals Inc., Puma Biotechnology Inc., Adlai Nortye Ltd., Arcus Biosciences Inc., Eisai Co. Ltd., G1 Therapeutics Inc., Simcere Pharmaceutical Group, Betta Pharmaceuticals Co. Ltd., Sihuan Pharmaceutical Holdings Group Ltd., Genor Biopharma Co. Ltd., Shanghai Fosun Pharmaceutical Group Co. Ltd.

North America was the largest region in the cyclin-dependent kinase (CDK) 4/6 inhibitor drugs market in 2025. The regions covered in the cyclin-dependent kinase (cdk) 4/6 inhibitor drugs market report are Asia-Pacific, South East Asia, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

The countries covered in the cyclin-dependent kinase (cdk) 4/6 inhibitor drugs market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Taiwan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

The cyclin-dependent kinase (CDK) 4/6 inhibitor drug market consists of sales of trilaciclib and ramiven drugs. Values in this market are 'factory gate' values, that is, the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market Global Report 2026 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.

This report focuses cyclin-dependent kinase (cdk) 4/6 inhibitor drugs market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.

Reasons to Purchase

Where is the largest and fastest growing market for cyclin-dependent kinase (cdk) 4/6 inhibitor drugs ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The cyclin-dependent kinase (cdk) 4/6 inhibitor drugs market global report from the Business Research Company answers all these questions and many more.

The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, total addressable market (TAM), market attractiveness score (MAS), competitive landscape, market shares, company scoring matrix, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.

Scope

Added Benefits available all on all list-price licence purchases, to be claimed at time of purchase. Customisations within report scope and limited to 20% of content and consultant support time limited to 8 hours.

Table of Contents

1. Executive Summary

2. Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market Characteristics

3. Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market Supply Chain Analysis

4. Global Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market Trends And Strategies

5. Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market Analysis Of End Use Industries

6. Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market - Macro Economic Scenario Including The Impact Of Interest Rates, Inflation, Geopolitics, Trade Wars and Tariffs, Supply Chain Impact from Tariff War & Trade Protectionism, And Covid And Recovery On The Market

7. Global Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Strategic Analysis Framework, Current Market Size, Market Comparisons And Growth Rate Analysis

8. Global Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Total Addressable Market (TAM) Analysis for the Market

9. Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market Segmentation

10. Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market Regional And Country Analysis

11. Asia-Pacific Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market

12. China Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market

13. India Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market

14. Japan Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market

15. Australia Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market

16. Indonesia Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market

17. South Korea Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market

18. Taiwan Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market

19. South East Asia Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market

20. Western Europe Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market

21. UK Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market

22. Germany Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market

23. France Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market

24. Italy Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market

25. Spain Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market

26. Eastern Europe Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market

27. Russia Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market

28. North America Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market

29. USA Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market

30. Canada Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market

31. South America Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market

32. Brazil Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market

33. Middle East Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market

34. Africa Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market

35. Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market Regulatory and Investment Landscape

36. Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market Competitive Landscape And Company Profiles

37. Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market Other Major And Innovative Companies

38. Global Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market Competitive Benchmarking And Dashboard

39. Key Mergers And Acquisitions In The Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market

40. Cyclin-Dependent Kinase (CDK) 4/6 Inhibitor Drugs Market High Potential Countries, Segments and Strategies

41. Appendix

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