세계의 순환종양 DNA(CtDNA) 메틸화 시장 보고서(2025년)
Circulating Tumor DNA (CtDNA) Methylation Global Market Report 2025
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리서치사 : The Business Research Company
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한글목차

순환종양 DNA(CtDNA) 메틸화 시장 규모는 최근 급속도로 확대되고 있습니다. 2024년 13억 달러에서 2025년에는 14억 8,000만 달러에 달하고, CAGR 13.6%로 확대될 전망입니다. 실적기간 내 성장의 원동력은 ctDNA 메틸화에 대한 임상 연구 증가, 정밀의료 전략의 채용 증가, 예후에서의 바이오마커 이용의 확대, ctDNA 메틸화 응용을 지지하는 연구 발표 증가, 고급 검사 자동화의 광범위한 도입 등입니다.

순환종양 DNA(CtDNA) 메틸화 시장 규모는 향후 수년간 급성장할 것으로 전망됩니다. 2029년에는 CAGR 13.2%로 24억 3,000만 달러로 성장할 전망입니다. 예측기간 내 성장은 포인트 오브 케어 ctDNA 검사 솔루션의 확대, 원격 진단을 위한 원격 의료 채용의 확대, 후성 바이오마커에 대한 세계적인 인지도 상승, 다른 업종 간의 파트너십 확대, 연구기관과 진단기업 간의 협력관계 강화 등에 의해 지원될 것으로 예상됩니다. 예측 기간 동안 예상되는 주요 동향으로는 메틸화 프로파일링을 위한 바이오인포매틱스의 통합, 치료 반응 모니터링의 진전, 집단 수준의 스크리닝 프로그램의 혁신, 자동 샘플 처리 시스템의 채용, 표적 치료 지침의 개발 등이 있습니다.

암의 유병률 상승이 향후 수년간 순환종양 DNA(CtDNA) 메틸화 시장의 성장을 가속화할 것으로 예측되고 있습니다. 암 이환율은 인구의 고령화와 건강에 해로운 식생활, 흡연, 운동 부족 등 생활 습관과 관련된 위험 인자에 의해 증가하고 있으며, 이들은 유전자 변이와 종양 형성의 원인이 되고 있습니다. 순환종양 DNA 메틸화 분석은 조기적이고 비침습적인 암의 검출을 지원하고, 질병의 진행을 정확하게 모니터링할 수 있게 해주며, 맞춤 치료 정책의 결정을 지원하고, 적시에 효과적인 임상 개입으로 이어집니다. 예를 들어 2024년 5월 미국 정부기관인 국립암연구소는 미국의 암 생존자 수가 2022년 1억 8,100만명에서 2040년에는 2,600만명으로 증가한 것으로 보고했습니다. 따라서 암의 유병률 증가가 ctDNA 메틸화 시장의 확대에 기여하고 있습니다.

순환종양 DNA 메틸화 시장의 주요 기업은 ctDNA의 암 특이적 메틸화 패턴을 해석하고 다양한 암종의 조기적 및 비침습적 검출을 가능하게 하는 다중암 조기진단 혈액 검사를 개발하고 있습니다. 이러한 검사는 명확한 메틸화 시그니처를 확인하여 임상 결과를 개선하고 시기 적절한 진단을 지원하며 정확한 치료 전략을 제공합니다. 예를 들어 미국을 거점으로 하는 분자진단회사 Exact Sciences Corporation은 2025년 9월 ctDNA 메틸화 해석을 통합한 다중암 조기진단 혈액 검사인 Cancerguard를 발표했습니다. Cancerguard는 50가지 이상의 암의 특정한 메틸화 패턴을 검출하고 고감도 비침습적 검출을 제공하는 동시에 임상 의사에게 지속적인 모니터링 및 치료 계획을 지원하는 유용한 인사이트를 제공합니다. 이 개발은 암의 조기 발견과 정밀 기반 치료에 중요한 진보입니다.

목차

제1장 주요 요약

제2장 시장 특징

제3장 시장 동향과 전략

제4장 시장 : 금리, 인플레이션, 지정학, 무역전쟁과 관세, 그리고 코로나 및 회복이 시장에 미치는 영향을 포함한 거시경제 시나리오

제5장 세계의 성장 분석과 전략 분석 프레임워크

제6장 시장 세분화

제7장 지역별/국가별 분석

제8장 아시아태평양 시장

제9장 중국 시장

제10장 인도 시장

제11장 일본 시장

제12장 호주 시장

제13장 인도네시아 시장

제14장 한국 시장

제15장 서유럽 시장

제16장 영국 시장

제17장 독일 시장

제18장 프랑스 시장

제19장 이탈리아 시장

제20장 스페인 시장

제21장 동유럽 시장

제22장 러시아 시장

제23장 북미 시장

제24장 미국 시장

제25장 캐나다 시장

제26장 남미 시장

제27장 브라질 시장

제28장 중동 시장

제29장 아프리카 시장

제30장 경쟁 구도와 기업 프로파일

제31장 기타 주요 기업 및 혁신 기업

제32장 세계 시장 경쟁 벤치마킹과 대시보드

제33장 주요 인수합병(M&A)

제34장 최근 시장 동향

제35장 시장의 잠재력이 높은 국가, 부문, 전략

제36장 부록

CSM
영문 목차

영문목차

Circulating tumor DNA (ctDNA) methylation refers to the addition of methyl groups to DNA fragments released by tumor cells into the bloodstream. This epigenetic modification influences gene expression and is frequently altered in cancer cells. Detecting ctDNA methylation patterns in blood enables non-invasive cancer diagnosis, monitoring of tumor progression, and evaluation of treatment response through liquid biopsy techniques.

The primary product types in the circulating tumor DNA (ctDNA) methylation market include reagents and kits, instrumentation, software and bioinformatics solutions, and services. Reagents and kits consist of consumable materials used in ctDNA methylation analysis, such as those for DNA extraction, bisulfite conversion, methylation detection, library preparation, and targeted enrichment. Key technologies include polymerase chain reaction (PCR), next-generation sequencing (NGS), microarray, and other methods. Sample types include blood, urine, saliva, tissue, and others. Major applications encompass oncology, cardiovascular diseases, neurological disorders, infectious diseases, and additional areas. End-users include hospitals and clinics, research and diagnostic laboratories, pharmaceutical and biotechnology companies, and academic institutions.

Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report's Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.

The fast surge in U.S. tariffs and the trade tensions that followed in spring 2025 are heavily affecting the medical equipment sector, particularly for imported imaging machine components, surgical-grade stainless steel, and plastic disposables. Hospitals and clinics resist price hikes, pressuring manufacturers' margins. Regulatory hurdles compound the problem, as tariff-related supplier changes often require re-certification of devices, delaying time-to-market. Companies are mitigating risks by dual-sourcing critical parts, expanding domestic production of commoditized items, and accelerating R&D in cost-efficient materials.

The circulating tumor DNA (ctDNA) methylation market research report is one of a series of new reports from The Business Research Company that provides circulating tumor DNA (ctDNA) methylation market statistics, including circulating tumor DNA (ctDNA) methylation industry global market size, regional shares, competitors with a circulating tumor DNA (ctDNA) methylation market share, detailed circulating tumor DNA (ctDNA) methylation market segments, market trends and opportunities, and any further data you may need to thrive in the circulating tumor DNA (ctDNA) methylation industry. The circulating tumor DNA (ctDNA) methylation market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The circulating tumor DNA (CtDNA) methylation market size has grown rapidly in recent years. It will grow from $1.30 billion in 2024 to $1.48 billion in 2025 at a compound annual growth rate (CAGR) of 13.6%. Growth in the historic period was driven by the rising number of clinical studies on ctDNA methylation, increasing adoption of precision medicine strategies, greater use of biomarkers for prognosis, growing publication of research supporting ctDNA methylation applications, and wider implementation of advanced laboratory automation.

The circulating tumor DNA (CtDNA) methylation market size is expected to see rapid growth in the next few years. It will grow to $2.43 billion in 2029 at a compound annual growth rate (CAGR) of 13.2%. Growth in the forecast period is expected to be supported by the expansion of point-of-care ctDNA testing solutions, increased adoption of telemedicine for remote diagnostics, rising global awareness of epigenetic biomarkers, growth in cross-industry partnerships, and greater collaboration between research institutes and diagnostic companies. Key trends anticipated for the forecast period include integration of bioinformatics for methylation profiling, advancements in treatment response monitoring, innovation in population-level screening programs, adoption of automated sample processing systems, and development of targeted therapy guidance.

The rising prevalence of cancer is expected to drive the growth of the circulating tumor DNA (ctDNA) methylation market in the coming years. Cancer rates are increasing due to aging populations and lifestyle-related risk factors such as unhealthy diets, tobacco use, and lack of physical activity, which contribute to genetic mutations and tumor formation. Circulating tumor DNA methylation assays support early and non-invasive cancer detection, enable accurate monitoring of disease progression, and assist in making personalized treatment decisions, leading to timely and effective clinical interventions. For example, in May 2024, the National Cancer Institute, a United States-based government agency, reported that the number of cancer survivors in the United States is projected to grow from eighteen point one million in 2022 to twenty six million by 2040. Therefore, the increasing prevalence of cancer is contributing to the expansion of the ctDNA methylation market.

Leading companies in the circulating tumor DNA methylation market are developing multi-cancer early detection blood tests that analyze cancer-specific methylation patterns in ctDNA to allow for early and non-invasive detection of various cancer types. These tests improve clinical outcomes by identifying distinct methylation signatures, supporting timely diagnosis and guiding precise treatment strategies. For instance, in September 2025, Exact Sciences Corporation, a United States-based molecular diagnostics company, introduced Cancerguard, a multi-cancer early detection blood test that incorporates ctDNA methylation analysis. Cancerguard detects specific methylation patterns across more than fifty types of cancer, offering sensitive and non-invasive detection while delivering useful insights for clinicians to support ongoing monitoring and treatment planning. This development marks a significant advancement in early cancer detection and precision-based care.

In January 2023, Agilent Technologies Incorporated, a United States-based provider of laboratory instruments, software, services, and consumables, acquired Avida Biomed Incorporated for an undisclosed amount. The acquisition aims to integrate Avida Biomed's target enrichment technologies to enhance Agilent's precision oncology offerings and broaden its role in molecular diagnostics. Avida Biomed is a biotechnology company based in the United States that develops circulating tumor DNA methylation technologies for sensitive, non-invasive, and targeted early cancer detection.

Major players in the circulating tumor DNA (ctDNA) methylation market are Thermo Fisher Scientific Inc., Agilent Technologies Inc., Illumina Inc., Sysmex Corporation, Bio-Rad Laboratories Inc., Exact Sciences Corporation, Qiagen N.V., Natera Inc., BGI Group, Guardant Health Inc., Invitae Corporation, Grail Inc., Genetron Holdings Limited, Buing Rock Biotech Limited, Zymo Research Corp, Agena Bioscience Inc., Phalanx Biotech Group Inc., Epigenomics Ag, EpigenDx Inc., Singlera Genomics Inc., Sampled.

North America was the largest region in the circulating tumor DNA (CtDNA) methylation market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in circulating tumor DNA (ctDNA) methylation report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

The countries covered in the circulating tumor DNA (ctDNA) methylation market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

The circulating tumor DNA (ctDNA) methylation market consists of revenues earned by entities by providing services such as early cancer detection services, prognostic testing services, clinical trial support services, liquid biopsy services, and epigenetic profiling services. The market value includes the value of related goods sold by the service provider or included within the service offering. The circulating tumor DNA (ctDNA) methylation market also includes sales of bisulfite conversion kits, methylation arrays, capillary electrophoresis systems, methyl-capture enrichment kits, and targeted methylation sequencing panels. Values in this market are 'factory gate' values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

Circulating Tumor DNA (CtDNA) Methylation Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.

This report focuses on circulating tumor dna (ctdna) methylation market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.

Reasons to Purchase

Where is the largest and fastest growing market for circulating tumor dna (ctdna) methylation ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The circulating tumor dna (ctdna) methylation market global report from the Business Research Company answers all these questions and many more.

The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.

The forecasts are made after considering the major factors currently impacting the market. These include the technological advancements such as AI and automation, Russia-Ukraine war, trade tariffs (government-imposed import/export duties), elevated inflation and interest rates.

Scope

Table of Contents

1. Executive Summary

2. Circulating Tumor DNA (CtDNA) Methylation Market Characteristics

3. Circulating Tumor DNA (CtDNA) Methylation Market Trends And Strategies

4. Circulating Tumor DNA (CtDNA) Methylation Market - Macro Economic Scenario Including The Impact Of Interest Rates, Inflation, Geopolitics, Trade Wars and Tariffs, And Covid And Recovery On The Market

5. Global Circulating Tumor DNA (CtDNA) Methylation Growth Analysis And Strategic Analysis Framework

6. Circulating Tumor DNA (CtDNA) Methylation Market Segmentation

7. Circulating Tumor DNA (CtDNA) Methylation Market Regional And Country Analysis

8. Asia-Pacific Circulating Tumor DNA (CtDNA) Methylation Market

9. China Circulating Tumor DNA (CtDNA) Methylation Market

10. India Circulating Tumor DNA (CtDNA) Methylation Market

11. Japan Circulating Tumor DNA (CtDNA) Methylation Market

12. Australia Circulating Tumor DNA (CtDNA) Methylation Market

13. Indonesia Circulating Tumor DNA (CtDNA) Methylation Market

14. South Korea Circulating Tumor DNA (CtDNA) Methylation Market

15. Western Europe Circulating Tumor DNA (CtDNA) Methylation Market

16. UK Circulating Tumor DNA (CtDNA) Methylation Market

17. Germany Circulating Tumor DNA (CtDNA) Methylation Market

18. France Circulating Tumor DNA (CtDNA) Methylation Market

19. Italy Circulating Tumor DNA (CtDNA) Methylation Market

20. Spain Circulating Tumor DNA (CtDNA) Methylation Market

21. Eastern Europe Circulating Tumor DNA (CtDNA) Methylation Market

22. Russia Circulating Tumor DNA (CtDNA) Methylation Market

23. North America Circulating Tumor DNA (CtDNA) Methylation Market

24. USA Circulating Tumor DNA (CtDNA) Methylation Market

25. Canada Circulating Tumor DNA (CtDNA) Methylation Market

26. South America Circulating Tumor DNA (CtDNA) Methylation Market

27. Brazil Circulating Tumor DNA (CtDNA) Methylation Market

28. Middle East Circulating Tumor DNA (CtDNA) Methylation Market

29. Africa Circulating Tumor DNA (CtDNA) Methylation Market

30. Circulating Tumor DNA (CtDNA) Methylation Market Competitive Landscape And Company Profiles

31. Circulating Tumor DNA (CtDNA) Methylation Market Other Major And Innovative Companies

32. Global Circulating Tumor DNA (CtDNA) Methylation Market Competitive Benchmarking And Dashboard

33. Key Mergers And Acquisitions In The Circulating Tumor DNA (CtDNA) Methylation Market

34. Recent Developments In The Circulating Tumor DNA (CtDNA) Methylation Market

35. Circulating Tumor DNA (CtDNA) Methylation Market High Potential Countries, Segments and Strategies

36. Appendix

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