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Portal Hypertension Management Global Market Report 2025
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Portal hypertension management encompasses strategies aimed at treating and preventing complications arising from elevated pressure in the portal vein system, often associated with liver cirrhosis. These measures include lifestyle adjustments, medication administration (such as beta-blockers), and procedures such as variceal banding to prevent or treat complications such as variceal bleeding and ascites.

The primary approaches to portal hypertension management include medication, non-surgical procedures, and surgery. Medication for portal hypertension typically includes nonselective beta-blockers, vasoconstrictors, diuretics, and antibiotics, which are used to manage conditions such as variceal bleeding, ascites, and bacterial infections in patients with increased portal pressure. Non-surgical procedures involve techniques such as transjugular intrahepatic portosystemic shunt (TIPS), which is employed across various healthcare settings including hospitals, specialty clinics, and others.

Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report's Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.

The sharp rise in U.S. tariffs and the resulting trade tensions in spring 2025 are having a significant impact on the healthcare sector, especially in the supply of essential medical devices, diagnostic equipment, and pharmaceuticals. Hospitals and healthcare providers are grappling with higher costs for imported surgical tools, imaging systems, and consumables like syringes and catheters, many of which have limited domestic substitutes. These escalating expenses are putting pressure on healthcare budgets, prompting some providers to delay equipment upgrades or pass increased costs on to patients. Furthermore, tariffs on raw materials and components are disrupting the manufacturing of vital drugs and devices, leading to supply chain delays. In response, the industry is adopting diversified sourcing strategies, expanding local production where feasible, and pushing for tariff exemptions on critical medical products.

The portal hypertension management research report is one of a series of new reports from The Business Research Company that provides portal hypertension management market statistics, including the portal hypertension management industry's global market size, regional shares, competitors with a portal hypertension management market share, detailed portal hypertension management market segments, market trends and opportunities, and any further data you may need to thrive in the portal hypertension management industry. This portal hypertension management market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.

The portal hypertension management market size has grown strongly in recent years. It will grow from $3.07 billion in 2024 to $3.27 billion in 2025 at a compound annual growth rate (CAGR) of 6.5%. The growth in the historic period can be attributed to the increased prevalence of liver diseases, growth in the geriatric population, awareness and screening programs, economic burden of liver diseases, approval done for new drugs and therapies, and improvement done for diagnostic methods.

The portal hypertension management market size is expected to see strong growth in the next few years. It will grow to $4.15 billion in 2029 at a compound annual growth rate (CAGR) of 6.2%. The growth in the forecast period can be attributed to rising investment in healthcare infrastructure, broader health insurance coverage, favorable regulatory environments and expedited approval processes, ongoing r&d activities focused on understanding the pathophysiology of portal hypertension, and remote monitoring technologies will facilitate continuous patient management. Major trends in the forecast period include growing adoption of telemedicine, continued advancements in medical technology, such as bio-engineered liver tissue, growth in personalized medicine, development of targeted therapies tailored to individual patient profiles, improved diagnostic methods, including non-invasive imaging technologies like elastography.

The forecast of 6.2% growth over the next five years reflects a modest reduction of 0.4% from the previous estimate for this market. This reduction is primarily due to the impact of tariffs between the US and other countries. Tariff barriers are expected to hamper the U.S. by increasing the cost of transjugular intrahepatic portosystemic shunt (TIPS) kits and hepatic venous pressure gradient (HVPG) monitoring devices sourced from Germany and Japan, thereby delaying critical interventions and elevating gastroenterology department expenditures. The effect will also be felt more widely due to reciprocal tariffs and the negative effect on the global economy and trade due to increased trade tensions and restrictions.

The portal hypertension management market is poised for growth due to an increasing prevalence of liver diseases such as hepatitis. Liver diseases encompass a spectrum of conditions affecting liver structure and function, often resulting in symptoms such as jaundice, fatigue, and abdominal pain. Causes include viral infections, alcohol abuse, and metabolic disorders. Management of portal hypertension in liver disease aims to alleviate complications such as variceal bleeding, ascites, and hepatic encephalopathy by reducing pressure in the portal vein system, thereby improving patient outcomes. For example, in 2022, Cancer Australia reported approximately 2,905 new cases of liver cancer diagnosed in Australia, underscoring the rising incidence contributing to market growth.

Leading companies in the portal hypertension management sector are advancing minimally invasive devices to enhance treatment efficacy and minimize procedural risks. These devices are designed to perform procedures with minimal disruption to tissues, typically through small incisions or natural body openings. For instance, Medtronic Plc received FDA approval in November 2023 for the Symplicity Spyral renal denervation system, utilizing radiofrequency energy to manage hypertension by targeting nerves near the kidneys.

In February 2023, AstraZeneca Plc acquired CinCor Pharma Inc. for $1.8 billion. This acquisition enriches AstraZeneca's portfolio with CinCor's barostat (CIN-107), an aldosterone synthase inhibitor designed to lower blood pressure in treatment-resistant hypertension. CinCor Pharma Inc., based in the US, specializes in developing innovative medications for hypertension management.

Major companies operating in the portal hypertension management market are Pfizer Inc., AbbVie Inc., Bayer AG, Sanofi SA, Bristol-Myers Squibb Company, AstraZeneca PLC, Novartis AG, GlaxoSmithKline plc, Eli Lilly and Company, Amgen Inc., Gilead Sciences Inc., Merck & Co., Boehringer Ingelheim International GmbH, Amneal Pharmaceuticals LLC., Lupin Ltd., Daiichi Sankyo, Dr. Falk Pharma GmbH, Cumberland Pharmaceuticals Inc., Ono Pharmaceutical Co. Ltd., Chiasma Inc., Debiovision Inc.

North America was the largest region in the portal hypertension management market in 2024. The regions covered in the portal hypertension management market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

The countries covered in the portal hypertension management market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

The portal hypertension management market consists of revenues earned by entities by provide services such as medical management, endoscopic therapy, interventional radiology procedures, and monitoring and supportive care. The market value includes the value of related goods sold by the service provider or included within the service offering. The portal hypertension management market also includes sales of nonselective beta-blockers, and vasoconstrictors. Values in this market are 'factory gate' values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

Portal Hypertension Management Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.

This report focuses on portal hypertension management market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.

Reasons to Purchase

Where is the largest and fastest growing market for portal hypertension management ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The portal hypertension management market global report from the Business Research Company answers all these questions and many more.

The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.

The forecasts are made after considering the major factors currently impacting the market. These include the technological advancements such as AI and automation, Russia-Ukraine war, trade tariffs (government-imposed import/export duties), elevated inflation and interest rates.

Scope

Table of Contents

1. Executive Summary

2. Portal Hypertension Management Market Characteristics

3. Portal Hypertension Management Market Trends And Strategies

4. Portal Hypertension Management Market - Macro Economic Scenario Including The Impact Of Interest Rates, Inflation, Geopolitics, Trade Wars and Tariffs, And Covid And Recovery On The Market

5. Global Portal Hypertension Management Growth Analysis And Strategic Analysis Framework

6. Portal Hypertension Management Market Segmentation

7. Portal Hypertension Management Market Regional And Country Analysis

8. Asia-Pacific Portal Hypertension Management Market

9. China Portal Hypertension Management Market

10. India Portal Hypertension Management Market

11. Japan Portal Hypertension Management Market

12. Australia Portal Hypertension Management Market

13. Indonesia Portal Hypertension Management Market

14. South Korea Portal Hypertension Management Market

15. Western Europe Portal Hypertension Management Market

16. UK Portal Hypertension Management Market

17. Germany Portal Hypertension Management Market

18. France Portal Hypertension Management Market

19. Italy Portal Hypertension Management Market

20. Spain Portal Hypertension Management Market

21. Eastern Europe Portal Hypertension Management Market

22. Russia Portal Hypertension Management Market

23. North America Portal Hypertension Management Market

24. USA Portal Hypertension Management Market

25. Canada Portal Hypertension Management Market

26. South America Portal Hypertension Management Market

27. Brazil Portal Hypertension Management Market

28. Middle East Portal Hypertension Management Market

29. Africa Portal Hypertension Management Market

30. Portal Hypertension Management Market Competitive Landscape And Company Profiles

31. Portal Hypertension Management Market Other Major And Innovative Companies

32. Global Portal Hypertension Management Market Competitive Benchmarking And Dashboard

33. Key Mergers And Acquisitions In The Portal Hypertension Management Market

34. Recent Developments In The Portal Hypertension Management Market

35. Portal Hypertension Management Market High Potential Countries, Segments and Strategies

36. Appendix

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