세계의 진행성 다초점 백질뇌병증 치료 시장 보고서(2025년)
Progressive Multifocal Leukoencephalopathy Treatment Global Market Report 2025
상품코드 : 1825524
리서치사 : The Business Research Company
발행일 : On Demand Report
페이지 정보 : 영문 250 Pages
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한글목차

진행성 다초점 백질뇌병증 치료 시장 규모는 향후 수년간 급성장이 전망됩니다. 2029년에는 CAGR 10.1%로 23억 5,000만 달러로 성장합니다. 예측 기간의 성장은 디지털 헬스 및 원격의료 증가, 표적 치료의 채택 확대, 진단 툴의 개선, 진행성 다발성 백혈병(PML)에 대한 인식 증가에 기인하는 것으로 보입니다. 예측 기간의 주요 동향으로는 진행성 다발성 백질뇌병증(PML) 치료 기술 발전, 연구개발 및 임상시험, 조기 진단 및 스크리닝, 신약 치료제 개발 등이 있습니다.

향후 5년간 성장률 10.1%라는 예측은 지난번 예측보다 0.1% 소폭 하락한 수치입니다. 이 감소는 주로 미국과 다른 국가 간의 관세의 영향에 기인합니다. 관세 부과로 인해 미국에서는 벨기에와 싱가포르에서 수입되는 단클론 항체 치료제와 특수 수액 분석 장비에 대한 접근이 차단되어 희귀질환 관리가 어려워지고, 신경계 감염 질환의 치료비 부담이 증가할 수 있습니다. 또한 상호 관세와 무역 긴장과 제한 증가로 인한 세계 경제와 무역에 대한 악영향으로 인해 그 영향은 더욱 광범위하게 나타날 것으로 보입니다.

진행성 다발성 백혈병 뇌병증(PML) 시장 확대는 인간면역결핍바이러스(HIV) 감염 증가가 원동력이 될 것으로 예측됩니다. 레트로바이러스의 일종인 HIV는 면역계, 특히 CD4 세포(T세포라고도 함)를 표적으로 삼아 감염에 대한 신체 방어에 중요한 역할을 합니다. PML은 CD4 세포 수 감소(200/L 이하)를 특징으로 하는 면역 결핍으로 인해 HIV 감염 환자에서 가장 흔하게 발생하며, 이는 전 세계 PML 사례의 주요 원인으로 작용합니다. HIV와 관련된 심각한 면역 결핍이 있으면 뇌에 잠복해 있던 존 커닝햄 바이러스(JCV)의 원형 균주가 활성화되어 뇌백질 병변과 PML의 발병으로 이어질 수 있습니다. 예를 들어 2022년 12월 현재 스위스에 본부를 둔 유엔의 에이즈 관련 구상인 유엔에이즈계획(UNAIDS)의 데이터에 따르면 63만 명(48만-88만 명)이 에이즈 관련 질병으로 사망하고, 전 세계 3,900만 명(3,310만-4,500만 명)이 에이즈에 감염된 것으로 나타났습니다. 570만 명)입니다. 2022년에는 130만 명(100만-170만 명)이 추가로 HIV 진단을 받을 것으로 예측됩니다. 그 결과, HIV 감염 유병률 증가는 진행성 다발성 백혈병 뇌병증 시장의 성장을 가속하는 주요 요인으로 작용하고 있습니다.

목차

제1장 개요

제2장 시장의 특징

제3장 시장 동향과 전략

제4장 시장 : 금리, 인플레이션, 지정학, 무역 전쟁과 관세 및 Covid와 회복이 시장에 미치는 영향을 포함한 거시경제 시나리오

제5장 세계의 성장 분석과 전략 분석 프레임워크

제6장 시장 세분화

제7장 지역별·국가별 분석

제8장 아시아태평양 시장

제9장 중국 시장

제10장 인도 시장

제11장 일본 시장

제12장 호주 시장

제13장 인도네시아 시장

제14장 한국 시장

제15장 서유럽 시장

제16장 영국 시장

제17장 독일 시장

제18장 프랑스 시장

제19장 이탈리아 시장

제20장 스페인 시장

제21장 동유럽 시장

제22장 러시아 시장

제23장 북미 시장

제24장 미국 시장

제25장 캐나다 시장

제26장 남미 시장

제27장 브라질 시장

제28장 중동 시장

제29장 아프리카 시장

제30장 경쟁 구도와 기업 개요

제31장 기타 대기업과 혁신적 기업

제32장 세계의 시장 경쟁 벤치마킹과 대시보드

제33장 주요 합병과 인수

제34장 최근 시장 동향

제35장 시장의 잠재력이 높은 국가, 부문, 전략

제36장 부록

KSA
영문 목차

영문목차

Progressive multifocal leukoencephalopathy is a rare and severe viral brain infection that primarily afflicts individuals with weakened immune systems. Treatment aims to manage symptoms, slow the disease's progression, and prevent complications. Unfortunately, there is currently no known cure for PML, and the damage caused by the virus cannot be reversed.

The main treatment approaches for progressive multifocal leukoencephalopathy include anti-retroviral therapy, antiviral or anti-John Cunningham virus (JCV) medications, and other interventions. Anti-retroviral therapy involves a combination of drugs used to manage infections caused by retroviruses, especially the human immunodeficiency virus (HIV). These therapies are employed in conditions such as HIV/AIDS, organ transplantation, multiple sclerosis, and hematologic malignancies. They can be administered through various methods, including oral and parenteral routes, and are utilized by a range of healthcare facilities, including hospitals, homecare services, specialty centers, and more.

Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report's Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.

The sharp rise in U.S. tariffs and the resulting trade tensions in spring 2025 are having a significant impact on the healthcare sector, especially in the supply of essential medical devices, diagnostic equipment, and pharmaceuticals. Hospitals and healthcare providers are grappling with higher costs for imported surgical tools, imaging systems, and consumables like syringes and catheters, many of which have limited domestic substitutes. These escalating expenses are putting pressure on healthcare budgets, prompting some providers to delay equipment upgrades or pass increased costs on to patients. Furthermore, tariffs on raw materials and components are disrupting the manufacturing of vital drugs and devices, leading to supply chain delays. In response, the industry is adopting diversified sourcing strategies, expanding local production where feasible, and pushing for tariff exemptions on critical medical products.

The progressive multifocal leukoencephalopathy market research report is one of a series of new reports from The Business Research Company that provides progressive multifocal leukoencephalopathy market statistics, including progressive multifocal leukoencephalopathy industry global market size, regional shares, competitors with a progressive multifocal leukoencephalopathy market share, detailed progressive multifocal leukoencephalopathy market segments, market trends and opportunities and any further data you may need to thrive in the progressive multifocal leukoencephalopathy industry. This progressive multifocal leukoencephalopathy market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The progressive multifocal leukoencephalopathy treatment market size has grown strongly in recent years. It will grow from $1.46 billion in 2024 to $1.6 billion in 2025 at a compound annual growth rate (CAGR) of 9.6%. The growth in the historic period can be attributed to prevalence of underlying conditions, rise in immunosuppressed patients, patient advocacy and awareness, rise of HIV/aids epidemic.

The progressive multifocal leukoencephalopathy treatment market size is expected to see rapid growth in the next few years. It will grow to $2.35 billion in 2029 at a compound annual growth rate (CAGR) of 10.1%. The growth in the forecast period can be attributed to increasing digital health and telemedicine, growing adoption of targeted therapy, improved diagnostic tools, growing awareness of progressive multifocal leukoencephalopathy (PML). Major trends in the forecast period include technological advancements in progressive multifocal leukoencephalopathy (PML) treatment, research and clinical trials, early diagnosis and screening, development of new drug therapies.

The forecast of 10.1% growth over the next five years reflects a slight reduction of 0.1% from the previous projection. This reduction is primarily due to the impact of tariffs between the US and other countries. The imposition of tariffs may disrupt U.S. access to monoclonal antibody therapies and specialized CSF analysis equipment imported from Belgium and Singapore, potentially compromising rare disease management and increasing neuroinfectious disease unit burdens. The effect will also be felt more widely due to reciprocal tariffs and the negative effect on the global economy and trade due to increased trade tensions and restrictions.

The expected increase in the prevalence of human immunodeficiency virus (HIV) infection is anticipated to be a driving force behind the expansion of the progressive multifocal leukoencephalopathy (PML) market. HIV, a retrovirus, targets the immune system, specifically CD4 cells (also known as T cells), which play a crucial role in the body's defense against infections. PML is most commonly observed in patients with HIV due to their compromised immune status, often characterized by a low CD4 cell count (below 200/L), which is the primary factor contributing to PML cases worldwide. When there is a severe immune deficiency related to HIV, the latent John Cunningham virus (JCV) archetype strain in the brain can become active, leading to the development of brain white matter lesions and PML. For instance, as of December 2022, data from the Joint United Nations Programme on HIV and AIDS (UNAIDS), a Switzerland-based United Nations initiative focused on AIDS, indicates that 630,000 (480,000-880,000) people succumbed to AIDS-related illnesses, and there were 39.0 million (33.1 million-45.7 million) individuals living with HIV worldwide. In 2022, an additional 1.3 million (1 million-1.7 million) people were newly diagnosed with HIV. Consequently, the increasing prevalence of HIV infection is a key factor propelling the growth of the progressive multifocal leukoencephalopathy market.

The growth of the progressive multifocal leukoencephalopathy (PML) treatment market is anticipated to be fueled by increasing research and development (R&D) activities. These activities encompass heightened efforts and investments in scientific exploration, experimentation, and innovation across various sectors. R&D is essential for advancing the treatment and management of PML, as it leads to the creation of improved therapies, earlier diagnoses, and enhanced disease management strategies. For example, in December 2023, Eurostat, a Luxembourg-based government agency, reported that the European Union allocated €352 billion ($380.40 billion) to R&D in 2022, marking a 6.34% increase from the €331 billion ($357.71 billion) invested in 2021. Thus, the rise in research and development efforts is driving growth in the PML treatment market.

Leading companies in the progressive multifocal leukoencephalopathy (PML) treatment market are increasingly dedicating their efforts to innovating their products to offer reliable solutions to their customers and to bolster their market standing. As an example, in October 2022, Cellevolve Bio, a clinical company based in the United States, obtained clearance from the United States Food and Drug Administration (FDA) for an investigational new drug (IND) application and secured orphan drug designation for CE-VST01-JC. This drug is developed to address progressive multifocal leukoencephalopathy and will undergo assessment in a global, multi-center, randomized, double-blind, placebo-controlled Phase 2 trial named ASCEND-JC. The primary objective of this trial is to compare the efficacy of CE-VST01-JC with a placebo, aiming to determine whether CE-VST01-JC can mitigate or prevent neurological progression in patients with PML. CE-VST01-JC is a T-cell therapy precisely targeting the JC virus, the causal agent of PML. This represents a significant milestone for both the PML community and Cellevolve, as ASCEND-JC stands as the largest-ever cell treatment study in the realm of PML research.

In March 2022, Cellevolve Bio, a US-based company focused on the treatment of progressive multifocal leukoencephalopathy, formed a partnership with Seattle Children's Therapeutics. This collaboration aims to enhance the BrainChild research program, which is dedicated to developing multiplex chimeric antigen receptors (CARs) for the treatment of pediatric central nervous system (CNS) malignancies. Seattle Children's Therapeutics is a non-profit enterprise in the United States that specializes in therapeutics development.

Major companies operating in the progressive multifocal leukoencephalopathy treatment market are Pfizer Inc., Johnson & Johnson, Roche Holding AG, Merck & Co. Inc., AbbVie Inc., Novartis AG, Bristol Myers Squibb Company, Sanofi S.A., Takeda Pharmaceutical Company Limited, Acorda Therapeutics, Eli Lilly and Company, Gilead Sciences Inc., Amgen Inc., Viatris Inc., Teva Pharmaceutical Industries Ltd., Biogen Inc., Eisai Co. Ltd., Otsuka Pharmaceutical Co. Ltd., Jazz Pharmaceuticals PLC, Ipsen Pharma, Apotex Inc., Alkermes PLC, Alnylam Pharmaceuticals Inc., Genentech Inc., Karyopharm Therapeutics Inc., ARIAD Pharmaceuticals Inc., Spectrum Pharmaceuticals, Neurimmune AG, NeoImmuneTech, Inhibikase Therapeutics Inc.

North America was the largest region in the progressive multifocal leukoencephalopathy treatment market in 2024. The regions covered in the progressive multifocal leukoencephalopathy treatment report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, the Middle East, and Africa.

The countries covered in the progressive multifocal leukoencephalopathy treatment market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, and Spain.

The progressive multifocal leukoencephalopathy treatment market consists of revenues earned by entities by providing plasmapheresis, immune reconstitution therapy, physical therapy, supportive care, and consultation. The market value includes the value of related goods sold by the service provider or included within the service offering. The progressive multifocal leukoencephalopathy treatment market also includes sales of cidofovir, Brin cidofovir, and mefloquine. Values in this market are 'factory gate' values, that is, the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

Progressive Multifocal Leukoencephalopathy Treatment Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.

This report focuses on progressive multifocal leukoencephalopathy treatment market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.

Reasons to Purchase

Where is the largest and fastest growing market for progressive multifocal leukoencephalopathy treatment ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The progressive multifocal leukoencephalopathy treatment market global report from the Business Research Company answers all these questions and many more.

The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.

The forecasts are made after considering the major factors currently impacting the market. These include the technological advancements such as AI and automation, Russia-Ukraine war, trade tariffs (government-imposed import/export duties), elevated inflation and interest rates.

Scope

Table of Contents

1. Executive Summary

2. Progressive Multifocal Leukoencephalopathy Treatment Market Characteristics

3. Progressive Multifocal Leukoencephalopathy Treatment Market Trends And Strategies

4. Progressive Multifocal Leukoencephalopathy Treatment Market - Macro Economic Scenario Including The Impact Of Interest Rates, Inflation, Geopolitics, Trade Wars and Tariffs, And Covid And Recovery On The Market

5. Global Progressive Multifocal Leukoencephalopathy Treatment Growth Analysis And Strategic Analysis Framework

6. Progressive Multifocal Leukoencephalopathy Treatment Market Segmentation

7. Progressive Multifocal Leukoencephalopathy Treatment Market Regional And Country Analysis

8. Asia-Pacific Progressive Multifocal Leukoencephalopathy Treatment Market

9. China Progressive Multifocal Leukoencephalopathy Treatment Market

10. India Progressive Multifocal Leukoencephalopathy Treatment Market

11. Japan Progressive Multifocal Leukoencephalopathy Treatment Market

12. Australia Progressive Multifocal Leukoencephalopathy Treatment Market

13. Indonesia Progressive Multifocal Leukoencephalopathy Treatment Market

14. South Korea Progressive Multifocal Leukoencephalopathy Treatment Market

15. Western Europe Progressive Multifocal Leukoencephalopathy Treatment Market

16. UK Progressive Multifocal Leukoencephalopathy Treatment Market

17. Germany Progressive Multifocal Leukoencephalopathy Treatment Market

18. France Progressive Multifocal Leukoencephalopathy Treatment Market

19. Italy Progressive Multifocal Leukoencephalopathy Treatment Market

20. Spain Progressive Multifocal Leukoencephalopathy Treatment Market

21. Eastern Europe Progressive Multifocal Leukoencephalopathy Treatment Market

22. Russia Progressive Multifocal Leukoencephalopathy Treatment Market

23. North America Progressive Multifocal Leukoencephalopathy Treatment Market

24. USA Progressive Multifocal Leukoencephalopathy Treatment Market

25. Canada Progressive Multifocal Leukoencephalopathy Treatment Market

26. South America Progressive Multifocal Leukoencephalopathy Treatment Market

27. Brazil Progressive Multifocal Leukoencephalopathy Treatment Market

28. Middle East Progressive Multifocal Leukoencephalopathy Treatment Market

29. Africa Progressive Multifocal Leukoencephalopathy Treatment Market

30. Progressive Multifocal Leukoencephalopathy Treatment Market Competitive Landscape And Company Profiles

31. Progressive Multifocal Leukoencephalopathy Treatment Market Other Major And Innovative Companies

32. Global Progressive Multifocal Leukoencephalopathy Treatment Market Competitive Benchmarking And Dashboard

33. Key Mergers And Acquisitions In The Progressive Multifocal Leukoencephalopathy Treatment Market

34. Recent Developments In The Progressive Multifocal Leukoencephalopathy Treatment Market

35. Progressive Multifocal Leukoencephalopathy Treatment Market High Potential Countries, Segments and Strategies

36. Appendix

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