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Neurotrophic Keratitis Treatment Global Market Report 2025
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Neurotrophic keratitis treatment is a method aimed at addressing a rare eye condition resulting from damage to the trigeminal nerve, leading to reduced corneal sensation and potential corneal harm. The objective of this treatment is to safeguard the cornea, facilitate recovery, alleviate symptoms, and prevent further damage. aimed at addressing a rare.

The main approaches of neurotrophic keratitis treatment are employed in neurotrophic keratitis treatment, including topical antibiotics, recombinant human nerve growth factor (rhNGF), amniotic membrane transplantation, keratoplasty, among others. Topical antibiotics are antimicrobial drugs administered directly to the skin or mucous membranes. They can be administered through various routes, such as oral, topical, and others, catering to stages I, II, and III of neurotropic keratitis. These treatments are utilized by different end-users, including hospitals, homecare, specialty clinics, among others.

Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report's Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.

The sharp rise in U.S. tariffs and the resulting trade tensions in spring 2025 are having a significant impact on the healthcare sector, especially in the supply of essential medical devices, diagnostic equipment, and pharmaceuticals. Hospitals and healthcare providers are grappling with higher costs for imported surgical tools, imaging systems, and consumables like syringes and catheters, many of which have limited domestic substitutes. These escalating expenses are putting pressure on healthcare budgets, prompting some providers to delay equipment upgrades or pass increased costs on to patients. Furthermore, tariffs on raw materials and components are disrupting the manufacturing of vital drugs and devices, leading to supply chain delays. In response, the industry is adopting diversified sourcing strategies, expanding local production where feasible, and pushing for tariff exemptions on critical medical products.

The neurotrophic keratitis treatment market research report is one of a series of new reports from The Business Research Company that provides neurotrophic keratitis treatment market statistics, including neurotrophic keratitis treatment industry global market size, regional shares, competitors with a neurotrophic keratitis treatment market share, detailed neurotrophic keratitis treatment market segments, market trends and opportunities and any further data you may need to thrive in the neurotrophic keratitis treatment industry. This neurotrophic keratitis treatment market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.

The neurotrophic keratitis treatment market size has grown exponentially in recent years. It will grow from $1.08 billion in 2024 to $1.47 billion in 2025 at a compound annual growth rate (CAGR) of 36.3%. The growth in the historic period can be attributed to increased diagnoses, increasing injury and surgical procedures, rising research and development, global healthcare infrastructure.

The neurotrophic keratitis treatment market size is expected to see exponential growth in the next few years. It will grow to $4.99 billion in 2029 at a compound annual growth rate (CAGR) of 35.9%. The growth in the forecast period can be attributed to educational initiatives, increasing clinical trials, advanced therapies, regulatory approvals. Major trends in the forecast period include improved diagnostic tools, digital health solutions, neuroprotection strategies, advanced ocular surface imaging.

The forecast of 35.9% growth over the next five years remains unchanged from the previous projection for this market. This reduction is primarily due to the impact of tariffs between the US and other countries. The imposition of tariffs may pose a significant challenge for the U.S. by restricting access to recombinant nerve growth factor (NGF) eye drops imported from Italy and France, potentially worsening corneal healing and increasing ophthalmology clinic costs. The effect will also be felt more widely due to reciprocal tariffs and the negative effect on the global economy and trade due to increased trade tensions and restrictions.

The increasing prevalence of eye diseases is expected to drive the growth of the neurotrophic keratitis treatment market in the coming years. Eye diseases encompass a wide range of conditions that impact the structure and function of the eyes. Neurotrophic keratitis is a condition that can help improve corneal sensation, promote healing, prevent infection, and alleviate pain. For example, in March 2022, Eye Care One, a U.S.-based eyecare career development platform, reported that an estimated 35 million people in the U.S. were affected by dry eye disease (DED) in 2022, with the prevalence expected to rise annually. Furthermore, in May 2024, the Centers for Disease Control and Prevention (CDC), a U.S. federal agency under the Department of Health and Human Services, stated that over 3.4 million Americans aged 40 and older are blind or visually impaired, a number expected to double by 2030. As a result, the growing prevalence of eye diseases is driving the expansion of the neurotrophic keratitis treatment market.

The growing investments in healthcare, particularly in eye care, are expected to drive the growth of the neurotrophic keratitis treatment market in the future. Investments in healthcare, including eye care, refer to the financial resources allocated to enhance the development, improvement, and accessibility of medical services and treatments, with a specific focus on vision-related health issues. These investments can play a pivotal role in advancing the treatment of neurotrophic keratitis, leading to breakthroughs in therapies, drug development, and ultimately improving patient outcomes and quality of life for those affected by the condition. For example, in March 2022, the Department of Health and Aged Care, an Australian government department overseeing health research and funding, reported that government investment in health systems amounted to $132 billion in 2022-23, with projections to increase to $140 billion by 2025-26, totaling $537 billion over the next four years. Therefore, the rise in healthcare investments, including in eye care, is contributing to the growth of the neurotrophic keratitis treatment market.

Major companies operating in the neurotrophic keratitis treatment market are focusing on developing innovative drugs to strengthen their market presence. Drug development is crucial in the treatment of neurotrophic keratitis, as current therapies are limited, and there is a pressing need for more effective treatments to halt disease progression. For example, in December 2022, BRIM Biotechnology Inc., a Taiwan-based clinical-stage company, received Orphan Drug Designation (ODD) from the U.S. Food and Drug Administration (FDA) for its drug BRM424, aimed at treating neurotrophic keratitis (NK). BRM424 is a recombinant human nerve growth factor that works by stimulating the proliferation and differentiation of corneal limbal stem cells, which helps regenerate and restore the cornea's health in patients with neurotrophic keratitis. This innovative approach reflects the ongoing efforts to address the unmet medical needs in this field.

In July 2022, Regenerx Biopharmaceuticals Inc., a US-based clinical-stage drug development company, along with its joint venture and licensee partner, HLB Therapeutics Co. Ltd., a biotechnology company based in South Korea, entered into a letter of intent with a global ophthalmology contract research organization (CRO). This collaboration is focused on conducting Phase III clinical trials in the US and Europe for the treatment of neurotrophic keratitis (NK). RGN-259, a sterile and preservative-free eye drop formulation containing thymosin beta 4, a naturally occurring peptide that facilitates tissue repair and healing, is the subject of evaluation. The Phase III clinical trial will assess the efficacy and safety of RGN-259 ophthalmic solution in promoting the healing of persistent epithelial defects in patients with Stages 2 and 3 neurotrophic keratopathies.clinical-stage drug development company.

Major companies operating in the neurotrophic keratitis treatment market are Eyevance Pharmaceuticals LLC, Grand Pharma Co. Ltd., Walgreen Co., Pfizer Inc., Johnson and Johnson, Bayer AG, Novartis AG, Abbott Laboratories, Gilead Biosciences Inc., Merck and Co. Inc., Allergan Inc., Alcon Inc., Bausch Health Companies Inc., Bausch & Lomb Inc., CooperVision Inc., Rohto Pharmaceutical Co. Ltd., Santen Pharmaceutical Co. Ltd., Zhejiang Conba Pharmaceutical Co. Ltd., Glenmark Pharmaceuticals Limited, Dompe farmaceutici S.p.A, Aurolab, Ocular Therapeutix Inc., Laboratoires Thea SAS, Leadiant Biosciences Inc., ReGenTree LLC, Contacare Opthalmic Private Limited, Neuroptika Inc., Surgitech Innovation Private Limited.

North America was the largest region in the neurotrophic keratitis treatment market in 2024. The regions covered in neurotrophic keratitis treatment report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

The countries covered in the neurotrophic keratitis treatment market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

The neurotrophic keratitis treatment market consists of revenues earned by entities by providing services such as ophthalmic evaluation, prescription of medications, corneal neurotization, customized treatment plans, counseling and support, tarsorrhaphy and antibiotic medication supplements. The market value includes the value of related goods sold by the service provider or included within the service offering. The neurotrophic keratitis market also includes sales of artificial tears, recombinant human nerve growth factor eye drops, antibiotics and bandage contact lenses. Values in this market are 'factory gate' values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

Neurotrophic Keratitis Treatment Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.

This report focuses on neurotrophic keratitis treatment market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.

Reasons to Purchase

Where is the largest and fastest growing market for neurotrophic keratitis treatment ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The neurotrophic keratitis treatment market global report from the Business Research Company answers all these questions and many more.

The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.

The forecasts are made after considering the major factors currently impacting the market. These include the technological advancements such as AI and automation, Russia-Ukraine war, trade tariffs (government-imposed import/export duties), elevated inflation and interest rates.

Scope

Table of Contents

1. Executive Summary

2. Neurotrophic Keratitis Treatment Market Characteristics

3. Neurotrophic Keratitis Treatment Market Trends And Strategies

4. Neurotrophic Keratitis Treatment Market - Macro Economic Scenario Including The Impact Of Interest Rates, Inflation, Geopolitics, Trade Wars and Tariffs, And Covid And Recovery On The Market

5. Global Neurotrophic Keratitis Treatment Growth Analysis And Strategic Analysis Framework

6. Neurotrophic Keratitis Treatment Market Segmentation

7. Neurotrophic Keratitis Treatment Market Regional And Country Analysis

8. Asia-Pacific Neurotrophic Keratitis Treatment Market

9. China Neurotrophic Keratitis Treatment Market

10. India Neurotrophic Keratitis Treatment Market

11. Japan Neurotrophic Keratitis Treatment Market

12. Australia Neurotrophic Keratitis Treatment Market

13. Indonesia Neurotrophic Keratitis Treatment Market

14. South Korea Neurotrophic Keratitis Treatment Market

15. Western Europe Neurotrophic Keratitis Treatment Market

16. UK Neurotrophic Keratitis Treatment Market

17. Germany Neurotrophic Keratitis Treatment Market

18. France Neurotrophic Keratitis Treatment Market

19. Italy Neurotrophic Keratitis Treatment Market

20. Spain Neurotrophic Keratitis Treatment Market

21. Eastern Europe Neurotrophic Keratitis Treatment Market

22. Russia Neurotrophic Keratitis Treatment Market

23. North America Neurotrophic Keratitis Treatment Market

24. USA Neurotrophic Keratitis Treatment Market

25. Canada Neurotrophic Keratitis Treatment Market

26. South America Neurotrophic Keratitis Treatment Market

27. Brazil Neurotrophic Keratitis Treatment Market

28. Middle East Neurotrophic Keratitis Treatment Market

29. Africa Neurotrophic Keratitis Treatment Market

30. Neurotrophic Keratitis Treatment Market Competitive Landscape And Company Profiles

31. Neurotrophic Keratitis Treatment Market Other Major And Innovative Companies

32. Global Neurotrophic Keratitis Treatment Market Competitive Benchmarking And Dashboard

33. Key Mergers And Acquisitions In The Neurotrophic Keratitis Treatment Market

34. Recent Developments In The Neurotrophic Keratitis Treatment Market

35. Neurotrophic Keratitis Treatment Market High Potential Countries, Segments and Strategies

36. Appendix

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