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Metastatic Melanoma Therapeutics Global Market Report 2025
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Metastatic melanoma therapeutics encompass a range of treatment options available for individuals diagnosed with metastatic melanoma, a type of skin cancer that has spread to other parts of the body. Melanoma arises from the transformation of pigmented cells called melanocytes, leading to the formation of tumors.

The primary types of metastatic melanoma therapeutics include chemotherapy, immunotherapy, targeted therapy, radiation therapy, and surgery. Chemotherapy involves the use of potent chemicals to eliminate rapidly proliferating cells in the body. The treatment may be administered at various stages, including stage 0, stage I, stage II, stage III, and stage IV, depending on the extent of the cancer. These therapeutic options are utilized by various healthcare providers, including hospitals, specialty clinics, home healthcare, and other medical facilities.

Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report's Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.

The sharp rise in U.S. tariffs and the resulting trade tensions in spring 2025 are having a significant impact on the healthcare sector, especially in the supply of essential medical devices, diagnostic equipment, and pharmaceuticals. Hospitals and healthcare providers are grappling with higher costs for imported surgical tools, imaging systems, and consumables like syringes and catheters, many of which have limited domestic substitutes. These escalating expenses are putting pressure on healthcare budgets, prompting some providers to delay equipment upgrades or pass increased costs on to patients. Furthermore, tariffs on raw materials and components are disrupting the manufacturing of vital drugs and devices, leading to supply chain delays. In response, the industry is adopting diversified sourcing strategies, expanding local production where feasible, and pushing for tariff exemptions on critical medical products.

The metastatic melanoma therapeutics market research report is one of a series of new reports from The Business Research Company that provides metastatic melanoma therapeutics market statistics, including metastatic melanoma therapeutics industry global market size, regional shares, competitors with a metastatic melanoma therapeutics market share, detailed metastatic melanoma therapeutics market segments, market trends and opportunities, and any further data you may need to thrive in the metastatic melanoma therapeutics industry. This metastatic melanoma therapeutics market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The metastatic melanoma therapeutics market size has grown rapidly in recent years. It will grow from $8.28 billion in 2024 to $9.29 billion in 2025 at a compound annual growth rate (CAGR) of 12.2%. The growth in the historic period can be attributed to pioneering immunotherapy approval, targeted therapy innovations, clinical trial successes, introduction of combination therapies, advancements in diagnostic technologies.

The metastatic melanoma therapeutics market size is expected to see rapid growth in the next few years. It will grow to $14.64 billion in 2029 at a compound annual growth rate (CAGR) of 12.1%. The growth in the forecast period can be attributed to expanding patient pool, research and development initiatives, biomarker identification, accelerated regulatory approvals, market expansion into emerging economies. Major trends in the forecast period include immunotherapy combinations, precision medicine advances, emerging targeted therapies, adjuvant therapies after surgery, development of bi-specific antibodies.

The forecast of 12.1% growth over the next five years reflects a slight reduction of 0.1% from the previous projection. This reduction is primarily due to the impact of tariffs between the US and other countries. The imposition of tariffs may disrupt U.S. immunotherapy access by increasing costs for PD-1 checkpoint inhibitors and BRAF/MEK inhibitor combinations imported from the UK and Singapore, potentially compromising survival outcomes and raising melanoma treatment costs. The effect will also be felt more widely due to reciprocal tariffs and the negative effect on the global economy and trade due to increased trade tensions and restrictions.

The anticipated growth in the metastatic melanoma therapeutics market is expected to be propelled by two significant factors. Firstly, the rising incidence of melanoma cases is poised to contribute to market expansion. Melanoma, a form of skin cancer originating in melanocytes, the pigment-regulating cells in the skin, can occur anywhere on the skin. Metastatic melanoma therapeutics encompass various treatments designed to block mutant chemicals and impede the growth of melanoma cells while minimizing harm to healthy tissue. According to the American Cancer Society, it is estimated that there will be 58,120 new cases of melanomas diagnosed in males and 39,490 in females in the US in 2023, totaling around 97,610 cases, with approximately 7,990 predicted deaths. The rising incidence of melanoma is a key driver for the growth of the metastatic melanoma therapeutics market.

The growing demand for biologics is expected to further propel market growth. Biologics, therapeutic products derived from living organisms or containing components of living organisms, have transformed the treatment landscape for metastatic melanoma. They offer targeted and immunotherapy-based approaches that have significantly improved patient outcomes with minimal side effects compared to traditional chemotherapy. For instance, according to the US Food and Drug Administration reported that by the end of 2022, 40 biosimilars had received approval, with 27 of them available in the United States, providing alternatives to 10 brand-name biologics. The growing demand for biologics, with their targeted and immunotherapy benefits, is a significant driver for the metastatic melanoma therapeutics market.

The metastatic melanoma therapeutics market is currently witnessing a significant trend towards product innovations, with companies strategically leveraging recent technologies to enhance their market standing. Notably, in January 2022, UK-based biotechnology firm Immunocore obtained FDA approval for KIMMTRAK, the first-ever FDA-approved T cell receptor (TCR) therapy designed for treating unresectable or metastatic uveal melanoma. Developed using Immunocore's ImmTAC technology platform, KIMMTRAK demonstrated a noteworthy overall survival (OS) advantage, boasting a hazard ratio of 0.51 and a median OS of nearly 22 months.

Leading companies in the metastatic melanoma therapeutics sector are actively engaging in strategic collaborations to assess treatments for metastatic cutaneous melanoma. An example of this is the collaboration between Immunocore and Sanofi, announced in June 2022. The partnership involves a clinical trial collaboration and supply agreement, wherein Sanofi will evaluate its engineered IL-2, SAR444245, in combination with Immunocore's KIMMTRAK in patients with advanced unresectable or metastatic skin cancers.

In April 2022, Germany-based investment firm EMZ Partners acquired a majority stake in FotoFinder Systems GmbH, a move undisclosed in terms of financial details. This strategic partnership aims to facilitate FotoFinder Systems GmbH's expansion of its product portfolio and market reach. FotoFinder Systems GmbH specializes in providing skin visualization equipment utilized in melanoma therapeutics.

Major companies operating in the metastatic melanoma therapeutics market include Pfizer Inc., F. Hoffmann-La Roche AG, Merck & Co. Inc., AbbVie Inc., Novartis AG, Bristol-Myers Squibb Company, AstraZeneca PLC, GlaxoSmithKline PLC, Takeda Pharmaceutical Company Limited, Eli Lilly and Company, Amgen Inc., Regeneron Pharmaceuticals Inc., Daiichi Sankyo Company Ltd., Eisai Co. Ltd., Incyte Corporation, Exelixis Inc., BeiGene Ltd, Immunocore Holdings plc, Genentech Inc., Iovance Biotherapeutics Inc., Nektar Therapeutics, Adaptimmune Therapeutics plc, AIVITA Biomedical Inc., Idera Pharmaceuticals Inc., Evaxion Biotech A/S, AB Science, AgonOX Inc., InxMed Co. Ltd., NewLink Genetics Corporation, Vical Inc.

North America was the largest region in the metastatic melanoma therapeutics market in 2024. The regions covered in the metastatic melanoma therapeutics market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

The countries covered in the metastatic melanoma therapeutics market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

The metastatic melanoma therapeutics market consists of sales of surgical resection, lymph node dissection, and lymphatic mapping and sentinel lymph node biopsy. The market value includes the value of related goods sold by the service provider or included within the service offering. The metastatic melanoma therapeutics market also includes sales of trametinib (Mekinist), cobimetinib (Cotellic), and binimetinib (Mektovi). Values in this market are 'factory gate' values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

Metastatic Melanoma Therapeutics Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.

This report focuses on metastatic melanoma therapeutics market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.

Reasons to Purchase

Where is the largest and fastest growing market for metastatic melanoma therapeutics ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The metastatic melanoma therapeutics market global report from the Business Research Company answers all these questions and many more.

The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.

The forecasts are made after considering the major factors currently impacting the market. These include the technological advancements such as AI and automation, Russia-Ukraine war, trade tariffs (government-imposed import/export duties), elevated inflation and interest rates.

Scope

Table of Contents

1. Executive Summary

2. Metastatic Melanoma Therapeutics Market Characteristics

3. Metastatic Melanoma Therapeutics Market Trends And Strategies

4. Metastatic Melanoma Therapeutics Market - Macro Economic Scenario Including The Impact Of Interest Rates, Inflation, Geopolitics, Trade Wars and Tariffs, And Covid And Recovery On The Market

5. Global Metastatic Melanoma Therapeutics Growth Analysis And Strategic Analysis Framework

6. Metastatic Melanoma Therapeutics Market Segmentation

7. Metastatic Melanoma Therapeutics Market Regional And Country Analysis

8. Asia-Pacific Metastatic Melanoma Therapeutics Market

9. China Metastatic Melanoma Therapeutics Market

10. India Metastatic Melanoma Therapeutics Market

11. Japan Metastatic Melanoma Therapeutics Market

12. Australia Metastatic Melanoma Therapeutics Market

13. Indonesia Metastatic Melanoma Therapeutics Market

14. South Korea Metastatic Melanoma Therapeutics Market

15. Western Europe Metastatic Melanoma Therapeutics Market

16. UK Metastatic Melanoma Therapeutics Market

17. Germany Metastatic Melanoma Therapeutics Market

18. France Metastatic Melanoma Therapeutics Market

19. Italy Metastatic Melanoma Therapeutics Market

20. Spain Metastatic Melanoma Therapeutics Market

21. Eastern Europe Metastatic Melanoma Therapeutics Market

22. Russia Metastatic Melanoma Therapeutics Market

23. North America Metastatic Melanoma Therapeutics Market

24. USA Metastatic Melanoma Therapeutics Market

25. Canada Metastatic Melanoma Therapeutics Market

26. South America Metastatic Melanoma Therapeutics Market

27. Brazil Metastatic Melanoma Therapeutics Market

28. Middle East Metastatic Melanoma Therapeutics Market

29. Africa Metastatic Melanoma Therapeutics Market

30. Metastatic Melanoma Therapeutics Market Competitive Landscape And Company Profiles

31. Metastatic Melanoma Therapeutics Market Other Major And Innovative Companies

32. Global Metastatic Melanoma Therapeutics Market Competitive Benchmarking And Dashboard

33. Key Mergers And Acquisitions In The Metastatic Melanoma Therapeutics Market

34. Recent Developments In The Metastatic Melanoma Therapeutics Market

35. Metastatic Melanoma Therapeutics Market High Potential Countries, Segments and Strategies

36. Appendix

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