부트리시란(Vutrisiran) 시장 보고서(2025년)
Vutrisiran Global Market Report 2025
상품코드 : 1815901
리서치사 : The Business Research Company
발행일 : On Demand Report
페이지 정보 : 영문 250 Pages
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한글목차

부트리시란 시장 규모는 향후 수년간 급성장할 것으로 전망됩니다. 2029년에는 CAGR 12.0%를 나타내 10억 6,000만 달러로 성장할 전망입니다. 예측 기간의 성장은 건강관리의 가용성 증가, 만성질환의 유병률 증가, 연구개발 투자 증가, 맞춤형 의료에 대한 관심 증가, 질병에 대한 의식 증가로 인한 것으로 예측됩니다. 예측 기간의 주요 동향으로는 병용요법의 개발, 표적요법의 채용, 맞춤형 의료의 진전, 디지털 헬스 기술의 개발, 생명공학의 진전 등을 들 수 있습니다.

향후 5년간의 성장률 12.0%라고 하는 예측은 이 시장의 전회 예측으로부터 0.4%의 소폭의 감소를 반영하고 있습니다. 이 감소는 주로 미국과 다른 국가 간의 관세의 영향 때문입니다. 관세 인상은 네덜란드에서 생산되는 RNAi 치료제와 유전성 트랜스사이레틴 아밀로이드증 치료제의 비용을 증가시키고 노인 환자의 진행성 다발신경염 관리를 위태롭게 하기 때문에 미국 신경과에 지장을 줄 수 있습니다. 또한 상호관세와 무역의 긴장과 한계 증가로 인한 세계경제와 무역에 대한 악영향으로 인해 그 영향이 더욱 광범위해질 것으로 보입니다.

연구개발에 대한 투자 증가는 앞으로 수년간 부트리시란 시장 성장을 가속할 것으로 예측됩니다. 연구개발은 체계적인 조사와 실험을 통해 제품, 서비스, 프로세스를 혁신·강화하는 것입니다. R&D 투자 증가는 정부의 이니셔티브와 자금 제공, 의료 및 의약품 수요 증가, 지속가능성에 대한 노력, 환경 우려에 기인합니다. 연구개발에 대한 자금제공으로 제약기업은 임상시험을 실시하고 의약품의 장기적인 효능과 안전성을 입증하며 보다 폭넓은 규제당국의 승인으로 이어질 수 있습니다. 게다가, RNA 간섭(RNAi) 기술의 진보는 약물의 정확성을 향상시키고, 부작용을 최소화하고, 환자에게의 보급을 추진합니다. 예를 들어, 2023년 12월, 룩셈부르크에 본사를 둔 유럽연합(EU)의 통계국인 유로스타트는 EU의 연구개발비가 2022년에 3,520억 유로(3,844억 2,000만 달러)에 이르렀고, 전년 3,310억 유로(3,614억 8,000만 달러)에서 6.34% 증가했다고 보고했습니다. 그 결과, R&D 투자 증가가 부트리시란 시장 확대에 박차를 가하고 있습니다.

목차

제1장 주요 요약

제2장 시장 특징

제3장 시장 동향과 전략

제4장 시장 : 금리, 인플레이션, 지정학, 무역전쟁과 관세, 그리고 코로나 및 회복이 시장에 미치는 영향을 포함한 거시경제 시나리오

제5장 세계의 성장 분석과 전략 분석 프레임워크

제6장 시장 세분화

제7장 지역별/국가별 분석

제8장 아시아태평양 시장

제9장 중국 시장

제10장 인도 시장

제11장 일본 시장

제12장 호주 시장

제13장 인도네시아 시장

제14장 한국 시장

제15장 서유럽 시장

제16장 영국 시장

제17장 독일 시장

제18장 프랑스 시장

제19장 이탈리아 시장

제20장 스페인 시장

제21장 동유럽 시장

제22장 러시아 시장

제23장 북미 시장

제24장 미국 시장

제25장 캐나다 시장

제26장 남미 시장

제27장 브라질 시장

제28장 중동 시장

제29장 아프리카 시장

제30장 경쟁 구도와 기업 프로파일

제31장 세계 시장 경쟁 벤치마킹과 대시보드

제32장 주요 인수합병(M&A)

제33장 최근 시장 동향

제34장 시장의 잠재력이 높은 국가, 부문, 전략

제35장 부록

KTH
영문 목차

영문목차

Vutrisiran is a small interfering RNA (siRNA) therapy used to treat hereditary transthyretin-mediated (hATTR) amyloidosis. It works by silencing the transthyretin (TTR) gene, reducing abnormal TTR protein deposits responsible for polyneuropathy and organ damage. Vutrisiran helps slow disease progression while improving neurological function, mobility, and overall quality of life, offering the benefit of a longer dosing interval.

The primary drug classes for vutrisiran include antisense oligonucleotides, nucleic acids, nucleotides, nucleosides, and others. Antisense oligonucleotides (ASOs) are synthetic short DNA or RNA molecules designed to target specific mRNA sequences and regulate gene expression. Vutrisiran is administered through various routes, including oral, injectable, and subcutaneous, and is suitable for different patient demographics, including pediatric, adult, and geriatric populations. It is distributed through multiple channels, such as hospital pharmacies, retail pharmacies, online pharmacies, and others.

Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report's Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.

The sudden escalation of U.S. tariffs and the resulting trade tensions in spring 2025 are having a significant impact on the pharmaceutical sector. Companies are grappling with higher costs on imported active pharmaceutical ingredients (APIs), glass vials, and laboratory equipment-many of which have limited alternative sources. Generic drug manufacturers, already operating with minimal profit margins, are particularly affected, with some scaling back production of low-margin medications. Biotech firms are also experiencing delays in clinical trials due to shortages of specialized reagents linked to tariffs. In response, the industry is shifting API production to regions like India and Europe, building up inventory reserves, and advocating for tariff exemptions on essential medicines.

The vutrisiran market research report is one of a series of new reports from The Business Research Company that provides vutrisiran market statistics, including the vutrisiran industry global market size, regional shares, competitors with the vutrisiran market share, detailed vutrisiran market segments, market trends, and opportunities, and any further data you may need to thrive in the vutrisiran industry. This vutrisiran market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.

The vutrisiran market size has grown rapidly in recent years. It will grow from $0.6 billion in 2024 to $0.67 billion in 2025 at a compound annual growth rate (CAGR) of 11.8%. The growth in the historic period can be attributed to increasing awareness of hereditary transthyretin amyloidosis, rising clinical trials, increasing healthcare spending, rising patient preference for non-invasive administration methods, and rising genetic disorders.

The vutrisiran market size is expected to see rapid growth in the next few years. It will grow to $1.06 billion in 2029 at a compound annual growth rate (CAGR) of 12.0%. The growth in the forecast period can be attributed to increasing healthcare availability, rising prevalence of chronic diseases, increasing investment in research and development, growing focus on personalized medicine, and rising awareness of disease. Major trends in the forecast period include development in combination therapy, adoption of targeted therapy, advancement in personalized medicine, development in digital health technologies, and advancements in biotechnology.

The forecast of 12.0% growth over the next five years reflects a modest reduction of 0.4% from the previous estimate for this market. This reduction is primarily due to the impact of tariffs between the US and other countries. Tariff increases could hinder U.S. neurology departments by inflating costs of RNAi therapeutics and hereditary transthyretin amyloidosis treatments manufactured in the Netherlands, compromising management of progressive polyneuropathy in elderly patients. The effect will also be felt more widely due to reciprocal tariffs and the negative effect on the global economy and trade due to increased trade tensions and restrictions.

The increasing investment in research and development is expected to drive the growth of the vutrisiran market in the coming years. Research and development involve innovating and enhancing products, services, or processes through systematic investigation and experimentation. The rise in R&D investment is attributed to government initiatives and funding, increasing healthcare and pharmaceutical demands, sustainability efforts, and environmental concerns. Funding for research and development enables pharmaceutical companies to conduct clinical trials, demonstrating the drug's long-term efficacy and safety, leading to wider regulatory approvals. Additionally, advancements in RNA interference (RNAi) technology enhance the drug's precision, minimizing side effects and increasing patient adoption. For example, in December 2023, Eurostat, a Luxembourg-based statistical office of the European Union, reported that the European Union's research and development expenditure reached €352 billion ($384.42 billion) in 2022, reflecting a 6.34% increase from €331 billion ($361.48 billion) in the previous year. As a result, rising investments in research and development are fueling the expansion of the vutrisiran market.

Companies operating in the vutrisiran market are focusing on developing innovative treatments, such as subcutaneous RNAi therapeutics, to offer more convenient and less frequent dosing options for managing hereditary transthyretin-mediated (hATTR) amyloidosis. These therapeutics utilize RNA interference technology and are administered through injections under the skin, ensuring sustained drug release. This approach maintains consistent drug levels over time, enhancing patient convenience and adherence in treating polyneuropathy associated with hereditary transthyretin-mediated (hATTR) amyloidosis. For example, in June 2022, Alnylam Pharmaceuticals, a US-based biopharmaceutical company, announced that vutrisiran (AMVUTTRA) received approval from the Food and Drug Administration (FDA) for the treatment of polyneuropathy in adults with hereditary transthyretin-mediated (hATTR) amyloidosis. The drug significantly alleviates neuropathy symptoms and slows disease progression. In the HELIOS-A Phase 3 study, more than 50% of patients showed a reversal or halt in disease manifestations. AMVUTTRA has demonstrated a favorable safety profile, with no drug-related discontinuations or fatalities, and features a dosing regimen that may enhance patient compliance.

In April 2024, Medison Pharma, an Israel-based pharmaceutical company, collaborated with Alnylam Pharmaceuticals Inc. to extend the commercialization of RNAi therapeutics. This partnership seeks to increase global availability of Alnylam's innovative RNAi treatments, particularly for patients with rare diseases, by leveraging Medison's integrated commercialization platform across multiple regions, including LATAM, APAC, and other international markets. Alnylam Pharmaceuticals, Inc. is a US-based pharmaceutical company that manufactures vutrisiran.

The key player in the vutrisiran market is Alnylam Pharmaceuticals Inc.

North America was the largest region in the vutrisiran market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in vutrisiran report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

The countries covered in the vutrisiran market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

The vutrisiran market consists of sales of pre-filled syringes and vials for subcutaneous injection. Values in this market are 'factory gate' values, that is, the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).

The revenues for a specified geography are consumption values and are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

Vutrisiran Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.

This report focuses on vutrisiran market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.

Reasons to Purchase

Where is the largest and fastest growing market for vutrisiran ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The vutrisiran market global report from the Business Research Company answers all these questions and many more.

The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.

The forecasts are made after considering the major factors currently impacting the market. These include the technological advancements such as AI and automation, Russia-Ukraine war, trade tariffs (government-imposed import/export duties), elevated inflation and interest rates.

Scope

Table of Contents

1. Executive Summary

2. Vutrisiran Market Characteristics

3. Vutrisiran Market Trends And Strategies

4. Vutrisiran Market - Macro Economic Scenario Including The Impact Of Interest Rates, Inflation, Geopolitics, Trade Wars and Tariffs, And Covid And Recovery On The Market

5. Global Vutrisiran Growth Analysis And Strategic Analysis Framework

6. Vutrisiran Market Segmentation

7. Vutrisiran Market Regional And Country Analysis

8. Asia-Pacific Vutrisiran Market

9. China Vutrisiran Market

10. India Vutrisiran Market

11. Japan Vutrisiran Market

12. Australia Vutrisiran Market

13. Indonesia Vutrisiran Market

14. South Korea Vutrisiran Market

15. Western Europe Vutrisiran Market

16. UK Vutrisiran Market

17. Germany Vutrisiran Market

18. France Vutrisiran Market

19. Italy Vutrisiran Market

20. Spain Vutrisiran Market

21. Eastern Europe Vutrisiran Market

22. Russia Vutrisiran Market

23. North America Vutrisiran Market

24. USA Vutrisiran Market

25. Canada Vutrisiran Market

26. South America Vutrisiran Market

27. Brazil Vutrisiran Market

28. Middle East Vutrisiran Market

29. Africa Vutrisiran Market

30. Vutrisiran Market Competitive Landscape And Company Profiles

31. Global Vutrisiran Market Competitive Benchmarking And Dashboard

32. Key Mergers And Acquisitions In The Vutrisiran Market

33. Recent Developments In The Vutrisiran Market

34. Vutrisiran Market High Potential Countries, Segments and Strategies

35. Appendix

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