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Prescription Orthopedic Drugs Global Market Report 2025
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Prescription orthopedic drugs are medications specifically prescribed to treat musculoskeletal conditions affecting bones, joints, muscles, and ligaments. These drugs help relieve pain, reduce inflammation, and promote healing in orthopedic injuries and disorders such as arthritis, fractures, and tendonitis.

The primary types of prescription orthopedic drugs include nonsteroidal anti-inflammatory drugs (NSAIDs), opioids, corticosteroids, disease-modifying antirheumatic drugs (DMARDs), and others. NSAIDs are a class of medications that alleviate pain, inflammation, and fever by inhibiting enzymes responsible for prostaglandin production. These drugs are commonly used to manage conditions such as osteoarthritis, rheumatoid arthritis, and osteoporosis. They are distributed through hospital pharmacies, retail pharmacies, and online pharmacies.

Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report's Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.

The sudden escalation of U.S. tariffs and the resulting trade tensions in spring 2025 are having a significant impact on the pharmaceutical sector. Companies are grappling with higher costs on imported active pharmaceutical ingredients (APIs), glass vials, and laboratory equipment-many of which have limited alternative sources. Generic drug manufacturers, already operating with minimal profit margins, are particularly affected, with some scaling back production of low-margin medications. Biotech firms are also experiencing delays in clinical trials due to shortages of specialized reagents linked to tariffs. In response, the industry is shifting API production to regions like India and Europe, building up inventory reserves, and advocating for tariff exemptions on essential medicines.

The prescription orthopedic drugs market research report is one of a series of new reports from The Business Research Company that provides prescription orthopedic drugs market statistics, including the prescription orthopedic drugs industry's global market size, regional shares, competitors with a prescription orthopedic drugs market share, detailed prescription orthopedic drugs market segments, market trends and opportunities, and any further data you may need to thrive in the prescription orthopedic drugs industry. This prescription orthopedic drugs market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.

The prescription orthopedic drugs market size has grown strongly in recent years. It will grow from $48.41 billion in 2024 to $51.06 billion in 2025 at a compound annual growth rate (CAGR) of 5.5%. The growth in the historic period can be attributed to the rise in the prevalence of musculoskeletal disorders, the increase in the geriatric population, the growth in awareness of osteoporosis treatments, the expanding healthcare access in developing regions, and the increase in sports-related injuries worldwide.

The prescription orthopedic drugs market size is expected to see strong growth in the next few years. It will grow to $63.86 billion in 2029 at a compound annual growth rate (CAGR) of 5.8%. The growth in the forecast period can be attributed to growing demand for biologics, increasing geriatric population, expanding healthcare access in emerging markets, rising prevalence of chronic musculoskeletal disorders, and increasing investments in orthopedic drug research and development. Major trends in the forecast period include advancements in targeted biologics, adoption of regenerative medicine therapies, personalized drug formulations, advancements in minimally invasive delivery methods, enhanced drug efficacy through gene therapy, innovations in injectable formulations, and innovations in artificial intelligence for drug development and clinical decision-making.

The forecast of 5.8% growth over the next five years reflects a modest reduction of 0.3% from the previous estimate for this market. This reduction is primarily due to the impact of tariffs between the US and other countries. The imposition of tariffs may pose a significant challenge for sports medicine practices by increasing costs of viscosupplementation injections and bone healing biologics imported from Sweden and South Korea, potentially delaying post-surgical recovery and raising musculoskeletal care expenses. The effect will also be felt more widely due to reciprocal tariffs and the negative effect on the global economy and trade due to increased trade tensions and restrictions.

The growing prevalence of musculoskeletal disorders is expected to propel the expansion of the prescription orthopedic drugs market. Musculoskeletal disorders (MSDs) encompass injuries and conditions that impact the movement and function of the body's musculoskeletal system, including muscles, tendons, ligaments, nerves, and joints, leading to pain and restricted mobility. The rising occurrence of these disorders can be attributed to factors such as aging, occupational activities involving repetitive motions and awkward postures, sedentary lifestyles, inadequate nutrition, and genetic predispositions. Prescription orthopedic drugs play a crucial role in managing musculoskeletal disorders by alleviating pain, reducing inflammation, and promoting the healing process, ultimately improving mobility and overall quality of life. For example, in March 2023, the Office for Health Improvement and Disparities, a UK-based government department for public health, reported that 17.6% of individuals aged 16 and older in 2022 had a long-term musculoskeletal (MSK) condition, such as arthritis or persistent back or joint problems, an increase from 17.0% in 2021. Additionally, in July 2022, the World Health Organization, a Switzerland-based intergovernmental organization, estimated that approximately 1.71 billion people worldwide suffer from musculoskeletal disorders. As a result, the increasing prevalence of musculoskeletal disorders is fueling the growth of the prescription orthopedic drugs market.

Leading companies in the prescription orthopedic drugs sector are prioritizing the expansion of indications for their drugs to extend market reach, enhance patient outcomes, and address unmet medical needs across various orthopedic conditions. For instance, in January 2023, Heron Therapeutics Inc., a US-based biotechnology company, received FDA approval for the extended use of ZYNRELEF (bupivacaine and meloxicam) in soft tissue and orthopedic procedures, including foot and ankle surgeries. This extended-release formulation is specifically designed to provide prolonged pain relief for up to 72 hours, minimizing or eliminating the need for opioid medications post-surgery. The expanded indication now encompasses a wider range of orthopedic and soft tissue procedures, broadening its use in clinical settings. The drug's innovative dual-drug combination delivers both local anesthetic and anti-inflammatory effects, offering a comprehensive solution for managing post-operative pain while improving patient outcomes.

In April 2024, ProMed Pharma LLC, a US-based pharmaceutical company, acquired SpineThera Inc. for an undisclosed sum. Through this acquisition, ProMed aims to strengthen its drug delivery capabilities by utilizing SpineThera's expertise in extended-release injectable therapies, particularly in pain management for musculoskeletal and orthopedic conditions. SpineThera Inc. is a US-based company specializing in the development of extended-release injectable therapies for treating musculoskeletal conditions, including back pain and orthopedic disorders.

Major players in the prescription orthopedic drugs market are Pfizer Inc., Johnson & Johnson, Roche Holding AG, Merck KGaA, AbbVie Inc., Bayer AG, Sanofi S.A., Bristol-Myers Squibb Company, AstraZeneca plc, GSK Plc, Takeda Pharmaceutical Company Limited, Eli Lilly and Company, Amgen Inc., Teva Pharmaceutical Industries Ltd., Mylan N.V., Biogen Inc., UCB S.A., Allergan plc, Penardo Biotech Pvt. Ltd., Horizon Therapeutics plc.

North America was the largest region in the prescription orthopedic drugs market in 2024. The regions covered in prescription orthopedic drugs report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

The countries covered in the prescription orthopedic drugs market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

The prescription orthopedic drugs market consists of sales of products such as bisphosphonates, creams, gels, or patches, calcium and vitamin D supplements, and analgesics. Values in this market are 'factory gate' values, that is, the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

Prescription Orthopedic Drugs Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.

This report focuses on prescription orthopedic drugs market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.

Reasons to Purchase

Where is the largest and fastest growing market for prescription orthopedic drugs ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The prescription orthopedic drugs market global report from the Business Research Company answers all these questions and many more.

The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.

The forecasts are made after considering the major factors currently impacting the market. These include the technological advancements such as AI and automation, Russia-Ukraine war, trade tariffs (government-imposed import/export duties), elevated inflation and interest rates.

Scope

Table of Contents

1. Executive Summary

2. Prescription Orthopedic Drugs Market Characteristics

3. Prescription Orthopedic Drugs Market Trends And Strategies

4. Prescription Orthopedic Drugs Market - Macro Economic Scenario Including The Impact Of Interest Rates, Inflation, Geopolitics, Trade Wars and Tariffs, And Covid And Recovery On The Market

5. Global Prescription Orthopedic Drugs Growth Analysis And Strategic Analysis Framework

6. Prescription Orthopedic Drugs Market Segmentation

7. Prescription Orthopedic Drugs Market Regional And Country Analysis

8. Asia-Pacific Prescription Orthopedic Drugs Market

9. China Prescription Orthopedic Drugs Market

10. India Prescription Orthopedic Drugs Market

11. Japan Prescription Orthopedic Drugs Market

12. Australia Prescription Orthopedic Drugs Market

13. Indonesia Prescription Orthopedic Drugs Market

14. South Korea Prescription Orthopedic Drugs Market

15. Western Europe Prescription Orthopedic Drugs Market

16. UK Prescription Orthopedic Drugs Market

17. Germany Prescription Orthopedic Drugs Market

18. France Prescription Orthopedic Drugs Market

19. Italy Prescription Orthopedic Drugs Market

20. Spain Prescription Orthopedic Drugs Market

21. Eastern Europe Prescription Orthopedic Drugs Market

22. Russia Prescription Orthopedic Drugs Market

23. North America Prescription Orthopedic Drugs Market

24. USA Prescription Orthopedic Drugs Market

25. Canada Prescription Orthopedic Drugs Market

26. South America Prescription Orthopedic Drugs Market

27. Brazil Prescription Orthopedic Drugs Market

28. Middle East Prescription Orthopedic Drugs Market

29. Africa Prescription Orthopedic Drugs Market

30. Prescription Orthopedic Drugs Market Competitive Landscape And Company Profiles

31. Prescription Orthopedic Drugs Market Other Major And Innovative Companies

32. Global Prescription Orthopedic Drugs Market Competitive Benchmarking And Dashboard

33. Key Mergers And Acquisitions In The Prescription Orthopedic Drugs Market

34. Recent Developments In The Prescription Orthopedic Drugs Market

35. Prescription Orthopedic Drugs Market High Potential Countries, Segments and Strategies

36. Appendix

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