콜린에스테라아제(ChE) 억제제 시장 보고서(2025년)
Cholinesterase (ChE) Inhibitors Global Market Report 2025
상품코드 : 1815882
리서치사 : The Business Research Company
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한글목차

콜린에스테라아제(ChE) 억제제 시장 규모는 향후 수년간 강력한 성장이 예상됩니다. 2029년에는 CAGR 7.4%를 나타내 55억 8,000만 달러로 성장할 전망입니다. 예측 기간의 성장은 신경퇴행성 질환의 조기진단, 조기진단과 치료에 대한 수요 증가, 신제품 및 신약상시 증가, 알츠하이머병 및 치매분야의 치료에 대한 높은 요구, 콜린에스테라아제 억제제의 경제적 중요성 증가 등에 기인한다고 생각됩니다. 예측 기간의 주요 동향으로는 기술의 진보, 진단기술의 진보, 새로운 콜린에스테라아제 억제제의 개발, 신제품의 상시, 전략적 제휴, 타사에의 신규 투자 등을 들 수 있습니다.

향후 5년간의 성장률 7.4%라는 예측은 이 시장의 전회 예측으로부터 0.4%의 소폭의 감소를 반영하고 있습니다. 이 감소는 주로 미국과 다른 국가 간의 관세의 영향 때문입니다. 무역 마찰은 프랑스와 이스라엘에서 생산되는 콜린에스테라아제 억제제의 가격을 늘리고 치매 치료 옵션을 줄이고 인지 장애 치료 비용을 증가시켜 미국 알츠하이머 병 치료 센터를 억제할 수 있습니다. 또한 상호관세와 무역의 긴장과 한계 증가로 인한 세계경제와 무역에 대한 악영향으로 인해 그 영향이 더욱 광범위해질 것으로 보입니다.

알츠하이머병의 유병률 증가는 향후 콜린에스테라아제(ChE) 억제제 시장 성장을 가속할 것으로 예측됩니다. 알츠하이머병은 진행성 뇌질환으로 기억과 인지능력에 손상을 주고 결국 인지기능의 저하와 자립심의 상실로 이어집니다. 알츠하이머병의 유병률 증가는 노화, 평균 수명 연장, 유전적 소인, 라이프스타일 요인, 신경학적 위험 요인에 대한 노출 증가 등의 요인에 의해 초래됩니다. 콜린에스테라아제 억제제는 기억과 인지 기능에 필수적인 중요한 신경전달물질인 아세틸콜린의 분해를 방지함으로써 알츠하이머병의 관리를 돕습니다. 이 과정은 신경전달을 촉진하고, 증상의 진행을 늦추고, 일상생활 기능을 개선하며, 궁극적으로 알츠하이머병과 관련된 인지 기능의 저하를 해결할 수 있습니다. 예를 들어, 2024년 알츠하이머병 협회는 65세 이상의 미국인 중 약 690만 명이 알츠하이머병을 앓고 있으며, 그 73%가 75세 이상에서 발생하고 있다고 보고했습니다. 2050년까지는 1,270만 명의 미국인이 알츠하이머병을 앓을 가능성이 있다고 추산되었습니다. 이와 같이 알츠하이머병의 유병률 증가는 콜린에스테라아제(ChE) 억제제 시장 확대를 견인하고 있습니다.

목차

제1장 주요 요약

제2장 시장 특징

제3장 시장 동향과 전략

제4장 시장 : 금리, 인플레이션, 지정학, 무역전쟁과 관세, 그리고 코로나 및 회복이 시장에 미치는 영향을 포함한 거시경제 시나리오

제5장 세계의 성장 분석과 전략 분석 프레임워크

제6장 시장 세분화

제7장 지역별/국가별 분석

제8장 아시아태평양 시장

제9장 중국 시장

제10장 인도 시장

제11장 일본 시장

제12장 호주 시장

제13장 인도네시아 시장

제14장 한국 시장

제15장 서유럽 시장

제16장 영국 시장

제17장 독일 시장

제18장 프랑스 시장

제19장 이탈리아 시장

제20장 스페인 시장

제21장 동유럽 시장

제22장 러시아 시장

제23장 북미 시장

제24장 미국 시장

제25장 캐나다 시장

제26장 남미 시장

제27장 브라질 시장

제28장 중동 시장

제29장 아프리카 시장

제30장 경쟁 구도와 기업 프로파일

제31장 기타 주요 기업 및 혁신 기업

제32장 세계 시장 경쟁 벤치마킹과 대시보드

제33장 주요 인수합병(M&A)

제34장 최근 시장 동향

제35장 시장의 잠재력이 높은 국가, 부문, 전략

제36장 부록

KTH
영문 목차

영문목차

Cholinesterase (ChE) inhibitors are a class of medications that block the cholinesterase enzyme, which normally breaks down acetylcholine, a neurotransmitter essential for proper nerve signaling. By inhibiting this enzyme, these drugs increase acetylcholine levels, which improves communication between nerve cells and enhances cognitive and muscular function.

The main types of cholinesterase (ChE) inhibitors include reversible cholinesterase inhibitors, irreversible cholinesterase inhibitors, and acetylcholinesterase inhibitors. Reversible cholinesterase inhibitors temporarily block the activity of the cholinesterase enzyme, thereby raising acetylcholine levels in the nervous system. These drugs are primarily used to treat conditions such as Alzheimer's disease, myasthenia gravis, glaucoma, and pediatric urinary incontinence. They are commonly distributed through hospital pharmacies, retail pharmacies, and online pharmacies.

Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report's Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.

The sudden escalation of U.S. tariffs and the resulting trade tensions in spring 2025 are having a significant impact on the pharmaceutical sector. Companies are grappling with higher costs on imported active pharmaceutical ingredients (APIs), glass vials, and laboratory equipment-many of which have limited alternative sources. Generic drug manufacturers, already operating with minimal profit margins, are particularly affected, with some scaling back production of low-margin medications. Biotech firms are also experiencing delays in clinical trials due to shortages of specialized reagents linked to tariffs. In response, the industry is shifting API production to regions like India and Europe, building up inventory reserves, and advocating for tariff exemptions on essential medicines.

The cholinesterase (ChE) inhibitors market research report is one of a series of new reports from The Business Research Company that provides cholinesterase (ChE) inhibitors market statistics, including the cholinesterase (ChE) inhibitors industry global market size, regional shares, competitors with the cholinesterase (ChE) inhibitors market share, detailed cholinesterase (ChE) inhibitors market segments, market trends, and opportunities, and any further data you may need to thrive in the cholinesterase (ChE) inhibitors industry. This cholinesterase (ChE) inhibitors market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.

The cholinesterase (ChE) inhibitors market size has grown strongly in recent years. It will grow from $3.92 billion in 2024 to $4.2 billion in 2025 at a compound annual growth rate (CAGR) of 7.1%. The growth in the historic period can be attributed to the increasing prevalence of neurological disorders, increasing prevalence of Alzheimer's disease, prevalence of late disease in elderly people, increased percentage of aged people, expanding healthcare infrastructure, and growing prevalence of glaucoma.

The cholinesterase (ChE) inhibitors market size is expected to see strong growth in the next few years. It will grow to $5.58 billion in 2029 at a compound annual growth rate (CAGR) of 7.4%. The growth in the forecast period can be attributed to early diagnosis of neurodegenerative illnesses, rising demand for early diagnosis and treatment, increased launches of new products and drugs, high requirements for therapies in the field of Alzheimer's and dementia, and increased economic importance of cholinesterase inhibitors. Major trends in the forecast period include advancements in technologies, advancements in diagnostic technologies, the development of new cholinesterase inhibitors, the launching of new products, strategic collaborations, and new investments into other companies.

The forecast of 7.4% growth over the next five years reflects a modest reduction of 0.4% from the previous estimate for this market. This reduction is primarily due to the impact of tariffs between the US and other countries. Trade tensions could hinder U.S. Alzheimer's treatment centers by inflating prices of cholinesterase inhibitors manufactured in France and Israel, resulting in reduced dementia management options and higher cognitive disorder treatment costs. The effect will also be felt more widely due to reciprocal tariffs and the negative effect on the global economy and trade due to increased trade tensions and restrictions.

The increasing prevalence of Alzheimer's disease is expected to drive the growth of the cholinesterase (ChE) inhibitors market in the future. Alzheimer's disease is a progressive brain disorder that damages memory and cognitive skills, ultimately leading to cognitive decline and loss of independence. The rising prevalence of Alzheimer's is driven by factors such as an aging population, longer life expectancies, genetic predisposition, lifestyle factors, and increased exposure to neurological risk factors. Cholinesterase inhibitors help manage Alzheimer's disease by preventing the breakdown of acetylcholine, a key neurotransmitter vital for memory and cognitive function. This process enhances neural communication, slows symptom progression, and improves daily functioning, ultimately helping manage the cognitive decline associated with the disease. For example, in 2024, the Alzheimer's Association reported that around 6.9 million Americans aged 65 and older are affected by Alzheimer's, with 73% of cases occurring in individuals aged 75 and above. By 2050, it's estimated that 12.7 million Americans may have Alzheimer's. As such, the growing prevalence of Alzheimer's disease is driving the expansion of the cholinesterase inhibitors market.

Leading companies in the cholinesterase inhibitors market are developing innovative treatment options, such as once-weekly transdermal patches, to offer Alzheimer's patients more effective and consistent treatment with improved tolerability. A once-weekly transdermal patch is a medicated adhesive patch applied to the skin, which continuously delivers a controlled dose of medication into the bloodstream over seven days. For instance, in September 2022, Corium, Inc., a US-based pharmaceutical company, launched ADLARITY, the first FDA-approved once-weekly transdermal patch. This patch delivers donepezil, an acetylcholinesterase inhibitor, for Alzheimer's treatment, offering a convenient alternative to daily oral administration and ensuring continuous drug delivery through the skin with good tolerability.

In April 2024, Essential Pharma, a UK-based pharmaceutical company, acquired Reminyl, a cholinesterase inhibitor from Janssen Pharmaceutica NV, for an undisclosed amount. This acquisition is aimed at expanding Essential Pharma's portfolio in Alzheimer's disease treatment by adding Reminyl, a cholinesterase inhibitor used to manage mild to moderately severe dementia. Janssen Pharmaceutica NV, a Belgium-based pharmaceutical company, is well-known for its development of cholinesterase inhibitors.

Major players in the cholinesterase (che) inhibitors market are Pfizer Inc., F. Hoffmann-La Roche Ltd., Sanofi S.A., Novartis International AG, Takeda Pharmaceutical Company Limited, Merck KGaA, Viatris Inc., Teva Pharmaceutical Industries Ltd., C.H. Boehringer Sohn AG & Co. KG, Eisai Co. Ltd., Apotex Inc., Dr. Reddy's Laboratories Ltd., Hikma Pharmaceuticals plc, Amneal Pharmaceuticals Inc., Lupin Pharmaceuticals Inc., Torrent Pharmaceuticals Ltd., Essential Pharma Group, Tocris Bioscience, Sparsha Pharma, Janssen Pharmaceuticals.

North America was the largest region in the cholinesterase (ChE) inhibitors market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in cholinesterase (ChE) inhibitors report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

The countries covered in the cholinesterase (ChE) inhibitors market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

The cholinesterase (ChE) inhibitors market consists of sales of donepezil, rivastigmine, and galantamine. Values in this market are 'factory gate' values, that is, the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

Cholinesterase (ChE) Inhibitors Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.

This report focuses on cholinesterase (che) inhibitors market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.

Reasons to Purchase

Where is the largest and fastest growing market for cholinesterase (che) inhibitors ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward, including technological disruption, regulatory shifts, and changing consumer preferences? The cholinesterase (che) inhibitors market global report from the Business Research Company answers all these questions and many more.

The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.

The forecasts are made after considering the major factors currently impacting the market. These include the technological advancements such as AI and automation, Russia-Ukraine war, trade tariffs (government-imposed import/export duties), elevated inflation and interest rates.

Scope

Table of Contents

1. Executive Summary

2. Cholinesterase (ChE) Inhibitors Market Characteristics

3. Cholinesterase (ChE) Inhibitors Market Trends And Strategies

4. Cholinesterase (ChE) Inhibitors Market - Macro Economic Scenario Including The Impact Of Interest Rates, Inflation, Geopolitics, Trade Wars and Tariffs, And Covid And Recovery On The Market

5. Global Cholinesterase (ChE) Inhibitors Growth Analysis And Strategic Analysis Framework

6. Cholinesterase (ChE) Inhibitors Market Segmentation

7. Cholinesterase (ChE) Inhibitors Market Regional And Country Analysis

8. Asia-Pacific Cholinesterase (ChE) Inhibitors Market

9. China Cholinesterase (ChE) Inhibitors Market

10. India Cholinesterase (ChE) Inhibitors Market

11. Japan Cholinesterase (ChE) Inhibitors Market

12. Australia Cholinesterase (ChE) Inhibitors Market

13. Indonesia Cholinesterase (ChE) Inhibitors Market

14. South Korea Cholinesterase (ChE) Inhibitors Market

15. Western Europe Cholinesterase (ChE) Inhibitors Market

16. UK Cholinesterase (ChE) Inhibitors Market

17. Germany Cholinesterase (ChE) Inhibitors Market

18. France Cholinesterase (ChE) Inhibitors Market

19. Italy Cholinesterase (ChE) Inhibitors Market

20. Spain Cholinesterase (ChE) Inhibitors Market

21. Eastern Europe Cholinesterase (ChE) Inhibitors Market

22. Russia Cholinesterase (ChE) Inhibitors Market

23. North America Cholinesterase (ChE) Inhibitors Market

24. USA Cholinesterase (ChE) Inhibitors Market

25. Canada Cholinesterase (ChE) Inhibitors Market

26. South America Cholinesterase (ChE) Inhibitors Market

27. Brazil Cholinesterase (ChE) Inhibitors Market

28. Middle East Cholinesterase (ChE) Inhibitors Market

29. Africa Cholinesterase (ChE) Inhibitors Market

30. Cholinesterase (ChE) Inhibitors Market Competitive Landscape And Company Profiles

31. Cholinesterase (ChE) Inhibitors Market Other Major And Innovative Companies

32. Global Cholinesterase (ChE) Inhibitors Market Competitive Benchmarking And Dashboard

33. Key Mergers And Acquisitions In The Cholinesterase (ChE) Inhibitors Market

34. Recent Developments In The Cholinesterase (ChE) Inhibitors Market

35. Cholinesterase (ChE) Inhibitors Market High Potential Countries, Segments and Strategies

36. Appendix

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