세계의 조직 플라스미노겐 활성화 인자 시장 보고서(2025년)
Tissue Plasminogen Activator Global Market Report 2025
상품코드 : 1760727
리서치사 : The Business Research Company
발행일 : On Demand Report
페이지 정보 : 영문 175 Pages
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한글목차

조직 플라스미노겐 활성화 인자(tissue plasminogen activator) 시장 규모는 향후 몇 년 동안 강력한 성장세를 보일 것으로 예상되며, 2029년에는 9.0%의 연평균 복합 성장률(CAGR)로 53억 2,000만 달러에 달할 것으로 예측됩니다. 혈전증 위험이 높은 고령화, 빠른 혈전 용해제에 대한 수요 증가, 신흥국의 의료비 지출 증가, 폐색전증 유병률 증가, 새로운 치료 적응증을 찾기 위한 임상시험의 진행 등이 예측 기간 동안 성장을 견인할 것으로 보입니다. 주요 동향으로는 카테터 지시 혈전 용해 요법으로의 전환, 뇌졸중 분류에 인공지능의 통합, tPA 바이오시밀러의 등장, ARDS 및 코로나19 합병증에 대한 tPA 사용에 대한 연구 증가, 정밀 투약 기술 채택 등이 있습니다.

생활습관병의 유병률 증가는 조직 플라스미노겐 활성화 인자 시장의 성장을 가속할 것으로 예측됩니다. 주로 비감염성 질환인 이들 질환은 영양 부족, 운동 부족, 흡연, 과도한 음주와 같은 건강에 해로운 생활 습관에 기인하여 심혈관 질환, 당뇨병, 고혈압과 같은 증상을 유발합니다. 이러한 생활습관병의 급증은 식생활의 변화와 신체활동의 감소에 기인한 바가 크며, 앉아서 생활하는 습관은 신진대사의 건강을 해치고 혈전성 사건의 유발에 중요한 역할을 합니다. 조직 플라스미노겐 활성화 인자(tPA)는 허혈성 뇌졸중 및 심근경색과 관련된 위험한 혈전을 용해시킴으로써 이러한 장애의 결과에 대처하여 사망률을 낮추고 환자의 예후를 개선할 수 있습니다. 예를 들어, 영국 정부 기관인 Office for Health Improvement and Disparities의 데이터에 따르면, 2022년부터 2023년까지 영국 성인의 약 64.0%가 과체중 또는 비만이며, 이는 전년도 63.8%에서 증가한 것으로 나타났습니다. 밝혀졌습니다. 비만만 해도 성인의 26.2%가 앓고 있으며, 비만율은 남녀 간 비슷한 수준이었으나, 여성(58.6%)에 비해 남성(69.2%)의 과체중 유병률이 더 높았습니다. 이러한 생활습관병 증가가 조직 플라스미노겐 활성화 인자 수요를 견인하는 중요한 요인이 되고 있습니다.

조직 플라스미노겐 활성화 인자 시장의 주요 기업들은 뇌졸중 급성기 치료를 개선하기 위해 단회 혈전 용해제와 같은 혁신적인 치료법 개발에 주력하고 있습니다. 이러한 속효성 약물은 심근경색, 뇌경색, 폐색전증 등의 증상에서 혈전을 신속하게 파괴하고 정상적인 혈류를 회복시키기 위해 1회 정맥 투여로 투여됩니다. 예를 들어, 2025년 3월 미국 생명공학 기업 제네텍은 성인 급성 허혈성 뇌졸중(AIS) 치료제로 TNKase(Tenecteplase)를 미국 식품의약국(FDA)의 승인을 받았습니다. 이번 승인은 젠젠텍의 두 번째 뇌졸중 치료제로, TNKase는 액티바제(알테플라제)에 비해 60분간의 정맥주입이 아닌 5초간의 정맥주입으로 보다 효율적이고 간편한 치료방법을 제공합니다. 이번 승인은 TNKase가 Activase와 마찬가지로 AIS 환자에게 안전하고 효과적이라는 AcT 임상시험에서 얻은 확실한 임상적 근거를 바탕으로 이루어졌습니다. 이 혁신은 급성 허혈성 뇌졸중 환자의 장기적인 장애와 사망률을 감소시키는데 매우 중요한 치료의 신속성과 용이성을 개선할 것으로 기대됩니다.

목차

제1장 주요 요약

제2장 시장 특징

제3장 시장 동향과 전략

제4장 시장 - 금리, 인플레이션, 지정학, 무역 전쟁과 관세, 그리고 코로나재난과 회복이 시장에 미치는 영향을 포함한 거시경제 시나리오

제5장 세계의 성장 분석과 전략 분석 프레임워크

제6장 시장 세분화

제7장 지역별/국가별 분석

제8장 아시아태평양 시장

제9장 중국 시장

제10장 인도 시장

제11장 일본 시장

제12장 호주 시장

제13장 인도네시아 시장

제14장 한국 시장

제15장 서유럽 시장

제16장 영국 시장

제17장 독일 시장

제18장 프랑스 시장

제19장 이탈리아 시장

제20장 스페인 시장

제21장 동유럽 시장

제22장 러시아 시장

제23장 북미 시장

제24장 미국 시장

제25장 캐나다 시장

제26장 남미 시장

제27장 브라질 시장

제28장 중동 시장

제29장 아프리카 시장

제30장 경쟁 구도와 기업 개요

제31장 기타 주요 기업 및 혁신 기업

제32장 세계 시장 경쟁 벤치마킹과 대시보드

제33장 주요 인수합병(M&A)

제34장 최근 시장 동향

제35장 시장 잠재력이 높은 국가, 부문, 전략

제36장 부록

LSH
영문 목차

영문목차

Tissue plasminogen activator (tPA) is a serine protease enzyme primarily produced by endothelial cells that catalyzes the conversion of plasminogen into plasmin, the primary enzyme responsible for clot breakdown. It is commonly used as a thrombolytic agent in clinical settings for the treatment of acute ischemic stroke, pulmonary embolism, and myocardial infarction, helping to dissolve blood clots and restore normal blood flow.

The main product types of tissue plasminogen activator include alteplase, tenecteplase, reteplase, and others. Alteplase is a recombinant form of tPA that serves as a thrombolytic agent to dissolve blood clots in conditions such as acute ischemic stroke, myocardial infarction, and pulmonary embolism. These products are available in dosage forms such as powder for injection and solution for injection. They are distributed through various channels, including direct sales, distributors, online pharmacies, and retail pharmacies. These tPA products are used in applications such as thrombolysis for ischemic stroke, myocardial infarction, and pulmonary embolism, serving end users such as hospitals, specialized cardiac clinics, emergency medical services (EMS), and ambulatory surgical centers.

The tissue plasminogen activator market research report is one of a series of new reports from The Business Research Company that provides tissue plasminogen activator market statistics, including tissue plasminogen activator industry global market size, regional shares, competitors with a tissue plasminogen activator market share, detailed tissue plasminogen activator market segments, market trends and opportunities, and any further data you may need to thrive in the tissue plasminogen activator industry. This tissue plasminogen activator market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The tissue plasminogen activator market size has grown strongly in recent years. It will grow from $3.45 billion in 2024 to $3.77 billion in 2025 at a compound annual growth rate (CAGR) of 9.2%. The growth during the historic period can be attributed to the rising prevalence of ischemic stroke, an increasing incidence of myocardial infarction, growing awareness of thrombolytic therapy, improvements in emergency care infrastructure, and government initiatives aimed at reducing cardiovascular mortality.

The tissue plasminogen activator market size is expected to see strong growth in the next few years. It will grow to $5.32 billion in 2029 at a compound annual growth rate (CAGR) of 9.0%. The growth in the forecast period is expected to be driven by an aging population at higher risk of thrombosis, increasing demand for faster-acting thrombolytic agents, growing healthcare spending in emerging economies, a rising prevalence of pulmonary embolism, and ongoing clinical trials exploring new therapeutic indications. Key trends anticipated include a shift toward catheter-directed thrombolysis, the integration of artificial intelligence in stroke triage, the emergence of biosimilars for tPA, increasing research into tPA's use in ARDS and COVID-19 complications, and the adoption of precision dosing technologies.

The increasing prevalence of lifestyle-related disorders is anticipated to drive the growth of the tissue plasminogen activator market. These disorders, which are primarily non-communicable, stem from unhealthy lifestyle habits such as poor nutrition, lack of exercise, smoking, and excessive alcohol consumption, leading to conditions such as cardiovascular disease, diabetes, and hypertension. This surge in lifestyle-related disorders is largely due to shifting dietary patterns and decreased physical activity, with sedentary lifestyles playing a significant role in disrupting metabolic health and triggering thrombotic events. Tissue plasminogen activator (tPA) addresses the consequences of these disorders by dissolving dangerous blood clots, which are often associated with ischemic strokes and myocardial infarctions, thereby reducing mortality and improving outcomes for patients. For example, data from the Office for Health Improvement and Disparities, a UK government body, revealed that in 2022-2023, approximately 64.0% of adults in England were either overweight or obese, up from 63.8% in the previous year. Obesity alone affected 26.2% of adults, with men having a higher prevalence of being overweight (69.2%) compared to women (58.6%), though obesity rates were similar between the genders. This increase in lifestyle-related conditions is a key factor driving the demand for tissue plasminogen activator.

Major players in the tissue plasminogen activator market are focusing on developing innovative treatments, such as single-bolus thrombolytic agents, to improve acute stroke therapy. These fast-acting drugs are given in a single intravenous dose to quickly break down blood clots and restore normal blood flow in conditions such as myocardial infarction, stroke, or pulmonary embolism. For instance, in March 2025, Genentech Inc., a U.S.-based biotechnology company, received U.S. Food and Drug Administration (FDA) approval for TNKase (tenecteplase) as a treatment for acute ischemic stroke (AIS) in adults. This approval marks Genentech's second stroke management drug, with TNKase offering a more efficient and simpler treatment method compared to Activase (alteplase), requiring just a five-second intravenous bolus rather than a 60-minute infusion. The approval is based on robust clinical evidence from the AcT trial, which showed that TNKase is as safe and effective as Activase for AIS patients. This innovation is expected to improve the speed and ease of treatment, which is critical in reducing long-term disability and mortality in patients experiencing acute ischemic strokes.

In January 2023, Shalamar Institute of Health Sciences (SIHS), a medical complex based in Pakistan, signed a Memorandum of Understanding (MoU) with Services Institute of Medical Sciences (SIMS) to enhance collaboration between healthcare institutions in advancing stroke care. The agreement aims to establish a cooperative framework for improving patient outcomes through the coordinated use of tissue plasminogen activator (tPA) in stroke treatment. It includes the development of standardized thrombolytic protocols, joint clinical training programs, and efforts to align stroke management practices with global best practices and the institutions' capabilities. Services Institute of Medical Sciences (SIMS) is a public medical college in Pakistan.

Major players in the tissue plasminogen activator market are F. Hoffmann-La Roche Ltd., Bayer AG, Abbott Laboratories, Boehringer Ingelheim International GmbH, Genentech Inc., CHIESI Farmaceutici S.p.A., Cadila Pharmaceuticals Ltd., Lupin Ltd., Sigma-Aldrich, Gennova Biopharmaceuticals Ltd., Angde Biological Pharmaceutical Co. Ltd., Reliance Life Sciences, Cedarlane Laboratories, Microbix Biosystems, Taj Pharmaceuticals, BPS Bioscience, Aviva Systems Biology, Biotang Inc., Reprokine, and Molecular Depot.

North America was the largest region in the tissue plasminogen activator market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in tissue plasminogen activator report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

The countries covered in the tissue plasminogen activator market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

The tissue plasminogen activator market consists of sales of biosimilar formulations, recombinant tissue plasminogen activator (rtPA) variants, single-dose prefilled syringes, dual-chamber injection systems, and lyophilized tPA kits with diluent. Values in this market are 'factory gate' values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

Tissue Plasminogen Activator Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.

This report focuses on tissue plasminogen activator market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.

Reasons to Purchase

Where is the largest and fastest growing market for tissue plasminogen activator ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward? The tissue plasminogen activator market global report from the Business Research Company answers all these questions and many more.

The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.

The forecasts are made after considering the major factors currently impacting the market. These include the Russia-Ukraine war, rising inflation, higher interest rates, and the legacy of the COVID-19 pandemic.

Scope

Table of Contents

1. Executive Summary

2. Tissue Plasminogen Activator Market Characteristics

3. Tissue Plasminogen Activator Market Trends And Strategies

4. Tissue Plasminogen Activator Market - Macro Economic Scenario Including The Impact Of Interest Rates, Inflation, Geopolitics, Trade Wars and Tariffs, And Covid And Recovery On The Market

5. Global Tissue Plasminogen Activator Growth Analysis And Strategic Analysis Framework

6. Tissue Plasminogen Activator Market Segmentation

7. Tissue Plasminogen Activator Market Regional And Country Analysis

8. Asia-Pacific Tissue Plasminogen Activator Market

9. China Tissue Plasminogen Activator Market

10. India Tissue Plasminogen Activator Market

11. Japan Tissue Plasminogen Activator Market

12. Australia Tissue Plasminogen Activator Market

13. Indonesia Tissue Plasminogen Activator Market

14. South Korea Tissue Plasminogen Activator Market

15. Western Europe Tissue Plasminogen Activator Market

16. UK Tissue Plasminogen Activator Market

17. Germany Tissue Plasminogen Activator Market

18. France Tissue Plasminogen Activator Market

19. Italy Tissue Plasminogen Activator Market

20. Spain Tissue Plasminogen Activator Market

21. Eastern Europe Tissue Plasminogen Activator Market

22. Russia Tissue Plasminogen Activator Market

23. North America Tissue Plasminogen Activator Market

24. USA Tissue Plasminogen Activator Market

25. Canada Tissue Plasminogen Activator Market

26. South America Tissue Plasminogen Activator Market

27. Brazil Tissue Plasminogen Activator Market

28. Middle East Tissue Plasminogen Activator Market

29. Africa Tissue Plasminogen Activator Market

30. Tissue Plasminogen Activator Market Competitive Landscape And Company Profiles

31. Tissue Plasminogen Activator Market Other Major And Innovative Companies

32. Global Tissue Plasminogen Activator Market Competitive Benchmarking And Dashboard

33. Key Mergers And Acquisitions In The Tissue Plasminogen Activator Market

34. Recent Developments In The Tissue Plasminogen Activator Market

35. Tissue Plasminogen Activator Market High Potential Countries, Segments and Strategies

36. Appendix

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