세계의 사이토카인 방출 증후군 관리 시장 보고서(2025년)
Cytokine Release Syndrome Management Global Market Report 2025
상품코드 : 1760513
리서치사 : The Business Research Company
발행일 : On Demand Report
페이지 정보 : 영문 175 Pages
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한글목차

사이토카인 방출 증후군 관리 시장 규모는 향후 몇 년 동안 강력한 성장세를 보일 것으로 예상되며, 2029년까지 6.5%의 CAGR로 306억 9,000만 달러에 달할 것으로 예상됩니다. 예측 기간 동안 성장의 원동력은 진단 도구 및 치료에 대한 수요 증가, 정부 보조금 증가, 효과적인 치료법에 대한 수요 증가, 고령화, 공공 및 민간 기관의 이니셔티브 확대 등이 될 것으로 예상됩니다. 예측 기간의 주요 동향으로는 최소침습적 유방 생검 장비의 개발, 전략적 파트너십 및 제휴, 재택 항생제 주입 서비스, 새로운 약물전달 시스템의 출현, 감염 추적을 위한 전자 의료 기록의 통합 등을 들 수 있습니다.

표적 치료제의 사용 증가는 향후 몇 년 동안 사이토카인 방출 증후군 관리 시장의 성장을 촉진할 것으로 예상됩니다. 표적 치료제는 종양 발생에 관여하는 분자 경로를 표적으로 삼아 암의 성장과 확산을 막기 위해 특별히 고안된 치료법입니다. 표적 치료제의 증가는 주로 건강한 세포에 대한 피해를 최소화하면서 암세포를 정확하게 표적화할 수 있는 능력에 기인하며, 기존 치료법에 비해 치료 효과는 향상되고 부작용은 감소하는 등 CRS의 관리는 CAR-T 세포 치료제, 면역관문억제제 등 치료의 안전성과 유효성을 높이기 위해 심각한 염증 반응을 조절하여 표적 치료를 최적화하는 데 중요한 역할을 하고 있습니다. 예를 들어, 2024년 1월 미국 유전자 및 세포 치료학회(American Society of Gene and Cell Therapy)는 2023년 4분기에 임상 3상 시험 중인 유전자 치료제의 수가 10% 증가했다고 보고했습니다. 이에 따라 표적 치료제의 사용 확대가 사이토카인 방출 증후군 관리 시장의 성장을 견인하고 있습니다.

사이토카인 방출 증후군 관리 시장의 주요 기업들은 숙주 지향성 저분자 약물과 같은 혁신적인 치료법 개발에 주력하고 있으며, 감염이나 암과 싸우는 신체의 능력을 손상시키지 않고 면역 반응을 조절하여 사이토카인 폭풍의 심각성을 감소시키는 것을 목표로 하고 있습니다. 숙주 지향성 저분자 의약품은 숙주의 면역 신호전달 경로를 타겟으로 설계된 저분자 화합물로, 과도한 사이토카인 생성을 억제하고 면역체계의 과잉 활성화를 방지하여 CRS 관리에 도움을 줄 수 있습니다. 예를 들어, 2025년 4월 미국 생명공학 기업 사이토에이전트(CytoAgents Inc.)는 CAR-T 세포 치료 환자의 CRS 예방 및 치료를 위한 숙주 지향성 저분자 약물 CTO1681의 1b/2a상 임상 1b/2a상 시험에서 첫 번째 용량 증량 코호트가 성공적으로 종료되었다고 발표했습니다. 이 임상시험에서 CTO1681은 양호한 안전성 프로파일을 보였으며, 용량 제한 독성이나 CAR T 세포의 효능을 저해하지 않았습니다. 현재 진행 중인 임상시험은 CTO1681의 안전성, 내약성, 예비 유효성을 평가하고 권장 2상 용량을 결정하기 위한 것입니다.

목차

제1장 주요 요약

제2장 시장 특징

제3장 시장 동향과 전략

제4장 시장 - 금리, 인플레이션, 지정학, 무역 전쟁과 관세, 그리고 코로나와 회복이 시장에 미치는 영향을 포함한 거시경제 시나리오

제5장 세계의 성장 분석과 전략 분석 프레임워크

제6장 시장 세분화

제7장 지역별·국가별 분석

제8장 아시아태평양 시장

제9장 중국 시장

제10장 인도 시장

제11장 일본 시장

제12장 호주 시장

제13장 인도네시아 시장

제14장 한국 시장

제15장 서유럽 시장

제16장 영국 시장

제17장 독일 시장

제18장 프랑스 시장

제19장 이탈리아 시장

제20장 스페인 시장

제21장 동유럽 시장

제22장 러시아 시장

제23장 북미 시장

제24장 미국 시장

제25장 캐나다 시장

제26장 남미 시장

제27장 브라질 시장

제28장 중동 시장

제29장 아프리카 시장

제30장 경쟁 구도와 기업 개요

제31장 기타 주요 기업과 혁신적 기업

제32장 세계의 시장 경쟁 벤치마킹과 대시보드

제33장 주요 인수합병

제34장 최근의 시장 동향

제35장 시장 잠재력이 높은 국가, 부문, 전략

제36장 부록

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영문 목차

영문목차

Cytokine release syndrome (CRS) management involves medical strategies to control the excessive immune response caused by an overproduction of cytokines, often seen in conditions such as CAR-T cell therapy or certain infections. The management approach includes medications such as corticosteroids and cytokine inhibitors, supportive care, and, in some cases, intensive monitoring to prevent severe complications. Effective management is critical for reducing the risk of severe organ damage and improving patient outcomes.

The primary treatment options for CRS include monoclonal antibodies, corticosteroids, intravenous immunoglobulin (IVIG), targeted therapy, supportive care, and other treatments. Monoclonal antibodies are laboratory-engineered molecules that target specific cytokines or their receptors to regulate immune activity and manage CRS. These antibodies are used for a range of conditions, including chimeric antigen receptor (CAR) T-cell therapy, immune checkpoint inhibitors, hematopoietic stem cell transplantation (HSCT), autoimmune diseases, infections, and others. They can be administered intravenously (IV), subcutaneously (SC), orally, intramuscularly (IM), intrathecally, or by other methods. These treatments are provided through various channels, including hospital pharmacies, retail pharmacies, online pharmacies, specialty clinics, research institutions, and others.

The cytokine release syndrome management market research report is one of a series of new reports from The Business Research Company that provides cytokine release syndrome management market statistics, including cytokine release syndrome management industry global market size, regional shares, competitors with a cytokine release syndrome management market share, cytokine release syndrome management market segments, market trends, and opportunities, and any further data you may need to thrive in the cytokine release syndrome management industry. This cytokine release syndrome management market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The cytokine release syndrome management market size has grown strongly in recent years. It will grow from $22.32 billion in 2024 to $23.83 billion in 2025 at a compound annual growth rate (CAGR) of 6.8%. Growth during the historic period can be attributed to rising healthcare expenditures, increasing awareness, changing lifestyles, higher disposable incomes, the adoption of personalized medicine approaches, and greater use of targeted therapies.

The cytokine release syndrome management market size is expected to see strong growth in the next few years. It will grow to $30.69 billion in 2029 at a compound annual growth rate (CAGR) of 6.5%. Growth in the forecast period is expected to be driven by increased demand for diagnostic tools and treatments, growing government funding, a rising need for effective therapies, an aging population, and expanding initiatives by both public and private organizations. Key trends in the forecast period include the development of minimally invasive breast biopsy devices, strategic partnerships and collaborations, home-based antibiotic infusion services, the emergence of novel drug delivery systems, and the integration of electronic health records for infection tracking.

The increasing use of targeted therapies is expected to drive the growth of the cytokine release syndrome management market in the coming years. Targeted therapies are treatments specifically designed to block the growth and spread of cancer by targeting molecular pathways involved in tumor development. The rise in targeted therapies is mainly attributed to their ability to precisely target cancer cells while minimizing harm to healthy cells, which improves treatment efficacy and reduces side effects compared to traditional therapies. CRS management plays a vital role in optimizing targeted therapies by controlling severe inflammatory responses, thus enhancing the safety and effectiveness of treatments such as CAR-T cell therapy and immune checkpoint inhibitors. For example, in January 2024, the American Society of Gene and Cell Therapy reported that in the fourth quarter of 2023, the number of gene therapies in Phase III clinical trials increased by 10%, marking the first rise of this kind since the third quarter of 2022. Therefore, the growing use of targeted therapies is fueling the growth of the cytokine release syndrome management market.

Major companies in the cytokine release syndrome management market are focusing on developing innovative therapies, such as host-directed small molecule drugs, which aim to modulate the immune response and reduce the severity of cytokine storms without compromising the body's ability to fight infections or cancer. A host-directed small molecule drug is a low molecular weight compound designed to target immune signaling pathways in the host, helping manage CRS by suppressing excessive cytokine production and preventing immune system overactivation. For instance, in April 2025, CytoAgents Inc., a US-based biotechnology company, announced the successful completion of the first dose-escalation cohort in its Phase 1b/2a clinical trial of CTO1681, a host-directed small molecule drug aimed at preventing and treating CRS in patients receiving CAR T-cell therapy. The investigational therapy showed a favorable safety profile, with no dose-limiting toxicities or disruption to CAR T-cell efficacy. The ongoing trial is designed to assess the safety, tolerability, and preliminary efficacy of CTO1681 and determine the recommended Phase 2 dose.

In March 2024, Merck & Co., Inc., a US-based biopharmaceutical company, acquired Harpoon Therapeutics for $680 million to strengthen its oncology pipeline with innovative T-cell engager therapies. This acquisition integrates Harpoon's T-cell engager technology and lead candidate, MK-6070, currently in a Phase 1/2 trial for advanced cancers, enhancing Merck's immuno-oncology capabilities and expanding its portfolio of next-generation cancer therapies. Harpoon Therapeutics, a clinical-stage biopharmaceutical company, specializes in T-cell engagers for cancer treatment, focusing on its TriTAC-XR platform to reduce CRS and improve treatment efficacy.

Major players in the cytokine release syndrome management market are Pfizer Inc., Johnson & Johnson Private Limited, F. Hoffmann-La Roche Ltd., AbbVie Inc., Sanofi S.A., Bristol Myers Squibb Company, Novartis AG, GlaxoSmithKline plc, Amgen Inc., Gilead Sciences Inc., Regeneron Pharmaceuticals Inc., Genentech Inc., Incyte Corporation, Swedish Orphan Biovitrum AB, Biocon Limited, MacroGenics Inc., Legend Biotech Corporation, Bluebird Bio Inc., InflaRx N.V., and Humanigen Inc.

North America was the largest region in the cytokine release syndrome management market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in cytokine release syndrome management report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

The countries covered in the cytokine release syndrome management market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

The cytokine release syndrome management market consists of revenues earned by entities by providing services such as diagnostic testing, immunosuppressive therapy, supportive care, clinical trial services, and post-treatment monitoring to manage and treat patients affected by CRS. The market value includes the value of related goods sold by the service provider or included within the service offering. The cytokine release syndrome management market also includes sales of tocilizumab (actemra), siltuximab (sylvant), dexamethasone, ruxolitinib (jakafi), and ivig (intravenous immunoglobulin). Values in this market are 'factory gate' values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

Cytokine Release Syndrome Management Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.

This report focuses on cytokine release syndrome management market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.

Reasons to Purchase

Where is the largest and fastest growing market for cytokine release syndrome management ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward? The cytokine release syndrome management market global report from the Business Research Company answers all these questions and many more.

The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.

The forecasts are made after considering the major factors currently impacting the market. These include the Russia-Ukraine war, rising inflation, higher interest rates, and the legacy of the COVID-19 pandemic.

Scope

Table of Contents

1. Executive Summary

2. Cytokine Release Syndrome Management Market Characteristics

3. Cytokine Release Syndrome Management Market Trends And Strategies

4. Cytokine Release Syndrome Management Market - Macro Economic Scenario Including The Impact Of Interest Rates, Inflation, Geopolitics, Trade Wars and Tariffs, And Covid And Recovery On The Market

5. Global Cytokine Release Syndrome Management Growth Analysis And Strategic Analysis Framework

6. Cytokine Release Syndrome Management Market Segmentation

7. Cytokine Release Syndrome Management Market Regional And Country Analysis

8. Asia-Pacific Cytokine Release Syndrome Management Market

9. China Cytokine Release Syndrome Management Market

10. India Cytokine Release Syndrome Management Market

11. Japan Cytokine Release Syndrome Management Market

12. Australia Cytokine Release Syndrome Management Market

13. Indonesia Cytokine Release Syndrome Management Market

14. South Korea Cytokine Release Syndrome Management Market

15. Western Europe Cytokine Release Syndrome Management Market

16. UK Cytokine Release Syndrome Management Market

17. Germany Cytokine Release Syndrome Management Market

18. France Cytokine Release Syndrome Management Market

19. Italy Cytokine Release Syndrome Management Market

20. Spain Cytokine Release Syndrome Management Market

21. Eastern Europe Cytokine Release Syndrome Management Market

22. Russia Cytokine Release Syndrome Management Market

23. North America Cytokine Release Syndrome Management Market

24. USA Cytokine Release Syndrome Management Market

25. Canada Cytokine Release Syndrome Management Market

26. South America Cytokine Release Syndrome Management Market

27. Brazil Cytokine Release Syndrome Management Market

28. Middle East Cytokine Release Syndrome Management Market

29. Africa Cytokine Release Syndrome Management Market

30. Cytokine Release Syndrome Management Market Competitive Landscape And Company Profiles

31. Cytokine Release Syndrome Management Market Other Major And Innovative Companies

32. Global Cytokine Release Syndrome Management Market Competitive Benchmarking And Dashboard

33. Key Mergers And Acquisitions In The Cytokine Release Syndrome Management Market

34. Recent Developments In The Cytokine Release Syndrome Management Market

35. Cytokine Release Syndrome Management Market High Potential Countries, Segments and Strategies

36. Appendix

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