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Extreme Lateral Interbody Fusion (XLIF) Surgery Global Market Report 2025
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Extreme lateral interbody fusion (XLIF) surgery is a minimally invasive spinal fusion procedure designed to treat a range of spinal disorders. It involves accessing the spine through a lateral (side) approach, which helps avoid major back muscles and reduces recovery time. Specialized surgical instruments and neuromonitoring are used during the procedure to ensure safety.

Note that the outlook for this market is being affected by rapid changes in trade relations and tariffs globally. The report will be updated prior to delivery to reflect the latest status, including revised forecasts and quantified impact analysis. The report's Recommendations and Conclusions sections will be updated to give strategies for entities dealing with the fast-moving international environment.

The primary products related to XLIF surgery include XLIF interbody fusion systems and XLIF interbody cages. The procedure is applicable for various treatments, such as single-segment, multi-segment, and mini-open surgeries, and is used to address conditions such as spinal stenosis, herniated discs, and degenerative disc disease. These products are utilized by a wide range of end-users, including hospitals, ambulatory surgical centers, and orthopedic clinics.

The extreme lateral interbody fusion (XLIF) surgery market research report is one of a series of new reports from The Business Research Company that provides extreme lateral interbody fusion (XLIF) surgery market statistics, including extreme lateral interbody fusion (XLIF) surgery industry global market size, regional shares, competitors with a extreme lateral interbody fusion (XLIF) surgery market share, detailed extreme lateral interbody fusion (XLIF) surgery market segments, market trends and opportunities, and any further data you may need to thrive in the extreme lateral interbody fusion (XLIF) surgery industry. This extreme lateral interbody fusion (XLIF) surgery market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The extreme lateral interbody fusion (XLIF) surgery market size has grown strongly in recent years. It will grow from$1.49 billion in 2024 to $1.57 billion in 2025 at a compound annual growth rate (CAGR) of 6.0%. The growth during the historical period can be attributed to the rising prevalence of cancer, a growing use of plant-derived pharmaceuticals, increasing demand for natural and semi-synthetic drugs, expansion in oncology research and development, a larger geriatric population, and advancements in drug delivery mechanisms.

The extreme lateral interbody fusion (XLIF) surgery market size is expected to see strong growth in the next few years. It will grow to$1.96 billion in 2029 at a compound annual growth rate (CAGR) of 5.7%. The projected growth during the forecast period can be attributed to the increasing demand for chemotherapy drugs, the expansion of oncology research and development, rising healthcare spending, a growing prevalence of drug-resistant cancer cases, and the surge in personalized medicine approaches. Key trends expected in the forecast period include advancements in drug formulation and delivery systems, the adoption of combination therapies, the development of novel semi-synthetic alkaloid compounds, technological innovations in alkaloid extraction and purification, and strategic mergers and acquisitions among major industry players.

The increasing prevalence of spinal illnesses is expected to drive the growth of the extreme lateral interbody fusion (XLIF) surgery market in the coming years. Spinal illnesses encompass a wide range of conditions that affect the spine, including its bones (vertebrae), discs, nerves, spinal cord, and surrounding muscles and ligaments. One of the key contributors to the rise in spinal disorders is sedentary lifestyles, where prolonged sitting and limited physical activity lead to poor posture and weakened core muscles, increasing the risk of spinal degeneration and chronic back pain. XLIF surgery is essential for treating spinal illnesses as it minimally invasively restores disc height and spinal alignment, alleviates nerve compression, and stabilizes the spine, all without cutting through major back muscles. For example, in June 2024, the Australian Institute of Health and Welfare, an Australian government agency, reported that around 4.0 million people, or 16% of the population, were living with back problems in 2022. By 2023, back problems had become the third leading cause of disease burden in the country, accounting for 4.3% of the total disease burden. Consequently, the increasing incidence of spinal illnesses is significantly contributing to the growth of the XLIF surgery market.

In the XLIF surgery market, major companies are focusing on the development of innovative products, such as lateral plating systems, to reduce surgical time and promote faster patient recovery. Lateral plating systems are orthopedic implants used in spine surgery to provide stabilization and support by attaching plates to the lateral aspect (side) of the vertebrae, often used alongside interbody fusion procedures such as XLIF. For example, in August 2024, Globus Medical Inc., a medical device manufacturer based in the U.S., launched the ADIRA XLIF Plate System. This system offers a streamlined lateral plating solution with a secure coupling mechanism that aligns plates over interbody spacers for enhanced stability. It is compatible with bone screws and lateral minimally invasive surgery (MIS) anchors, supporting various fixation methods and spacer types. Integrated with Globus Medical's lateral portfolio, the system threads directly into multiple interbody spacers to minimize the risk of spacer movement and adapt to diverse patient needs and surgical preferences, improving both efficiency and reliability.

In September 2023, Globus Medical, a U.S.-based medical device company, merged with NuVasive to create a global musculoskeletal solutions provider. The merger between Globus Medical and NuVasive has resulted in the creation of one of the most comprehensive portfolios of musculoskeletal procedural solutions and enabling technologies, enhancing care across the entire treatment continuum. This strategic partnership combines complementary global reach, an expanded commercial presence, and strong offerings in both the spine and orthopedic segments. It also bolsters the companies' shared commitment to innovation, surgeon education, and operational excellence. NuVasive is a U.S.-based company specializing in XLIF products and solutions.

Major players in the extreme lateral interbody fusion (XLIF) surgery market are Medtronic plc, Stryker Corporation, Zimmer Biomet Holdings Inc., NuVasive Inc., Globus Medical Inc., Orthofix Medical Inc., Alphatec Holdings Inc. (Alphatec Spine), Spinal Elements Inc., Surgalign Holdings Inc., Spineology Inc., CoreLink LLC, Aurora Spine Corporation, Life Spine Inc., Premia Spine Ltd., Nexxt Spine LLC, TeDan Surgical Innovations LLC, Medfin India Pvt. Ltd., Spinal Simplicity LLC, CoreSpine Technologies LLC, NU-Spine LLC.

North America was the largest region in the extreme lateral interbody fusion (XLIF) surgery market in 2024. Asia-pacific is expected to be the fastest-growing region in the forecast period. The regions covered in extreme lateral interbody fusion (XLIF) surgery report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

The countries covered in the extreme lateral interbody fusion (XLIF) surgery market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

The extreme lateral interbody fusion (XLIF) surgery market consists of revenues earned by entities by providing services such as surgical training, intraoperative support, postoperative monitoring, reprocessing and sterilization services. The market value includes the value of related goods sold by the service provider or included within the service offering. The extreme lateral interbody fusion (XLIF) surgery market also includes sales of surgical access systems, fixation devices, neuromonitoring equipment and bone graft materials. Values in this market are 'factory gate' values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

Extreme Lateral Interbody Fusion (XLIF) Surgery Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.

This report focuses on extreme lateral interbody fusion (xlif) surgery market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.

Reasons to Purchase

Where is the largest and fastest growing market for extreme lateral interbody fusion (xlif) surgery ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward? The extreme lateral interbody fusion (xlif) surgery market global report from the Business Research Company answers all these questions and many more.

The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.

The forecasts are made after considering the major factors currently impacting the market. These include the Russia-Ukraine war, rising inflation, higher interest rates, and the legacy of the COVID-19 pandemic.

Scope

Table of Contents

1. Executive Summary

2. Extreme Lateral Interbody Fusion (XLIF) Surgery Market Characteristics

3. Extreme Lateral Interbody Fusion (XLIF) Surgery Market Trends And Strategies

4. Extreme Lateral Interbody Fusion (XLIF) Surgery Market - Macro Economic Scenario Including The Impact Of Interest Rates, Inflation, Geopolitics, Trade Wars and Tariffs, And Covid And Recovery On The Market

5. Global Extreme Lateral Interbody Fusion (XLIF) Surgery Growth Analysis And Strategic Analysis Framework

6. Extreme Lateral Interbody Fusion (XLIF) Surgery Market Segmentation

7. Extreme Lateral Interbody Fusion (XLIF) Surgery Market Regional And Country Analysis

8. Asia-Pacific Extreme Lateral Interbody Fusion (XLIF) Surgery Market

9. China Extreme Lateral Interbody Fusion (XLIF) Surgery Market

10. India Extreme Lateral Interbody Fusion (XLIF) Surgery Market

11. Japan Extreme Lateral Interbody Fusion (XLIF) Surgery Market

12. Australia Extreme Lateral Interbody Fusion (XLIF) Surgery Market

13. Indonesia Extreme Lateral Interbody Fusion (XLIF) Surgery Market

14. South Korea Extreme Lateral Interbody Fusion (XLIF) Surgery Market

15. Western Europe Extreme Lateral Interbody Fusion (XLIF) Surgery Market

16. UK Extreme Lateral Interbody Fusion (XLIF) Surgery Market

17. Germany Extreme Lateral Interbody Fusion (XLIF) Surgery Market

18. France Extreme Lateral Interbody Fusion (XLIF) Surgery Market

19. Italy Extreme Lateral Interbody Fusion (XLIF) Surgery Market

20. Spain Extreme Lateral Interbody Fusion (XLIF) Surgery Market

21. Eastern Europe Extreme Lateral Interbody Fusion (XLIF) Surgery Market

22. Russia Extreme Lateral Interbody Fusion (XLIF) Surgery Market

23. North America Extreme Lateral Interbody Fusion (XLIF) Surgery Market

24. USA Extreme Lateral Interbody Fusion (XLIF) Surgery Market

25. Canada Extreme Lateral Interbody Fusion (XLIF) Surgery Market

26. South America Extreme Lateral Interbody Fusion (XLIF) Surgery Market

27. Brazil Extreme Lateral Interbody Fusion (XLIF) Surgery Market

28. Middle East Extreme Lateral Interbody Fusion (XLIF) Surgery Market

29. Africa Extreme Lateral Interbody Fusion (XLIF) Surgery Market

30. Extreme Lateral Interbody Fusion (XLIF) Surgery Market Competitive Landscape And Company Profiles

31. Extreme Lateral Interbody Fusion (XLIF) Surgery Market Other Major And Innovative Companies

32. Global Extreme Lateral Interbody Fusion (XLIF) Surgery Market Competitive Benchmarking And Dashboard

33. Key Mergers And Acquisitions In The Extreme Lateral Interbody Fusion (XLIF) Surgery Market

34. Recent Developments In The Extreme Lateral Interbody Fusion (XLIF) Surgery Market

35. Extreme Lateral Interbody Fusion (XLIF) Surgery Market High Potential Countries, Segments and Strategies

36. Appendix

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