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Cholangiocarcinoma Global Market Report 2025
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Cholangiocarcinoma is a malignant tumor that develops in the bile ducts, which transport bile from the liver to the small intestine. It is characterized by the uncontrolled growth of abnormal cells, leading to bile duct obstruction and liver dysfunction. Common symptoms include jaundice, abdominal pain, weight loss, and fatigue. Early diagnosis and timely treatment are essential for improving prognosis and disease management.

The primary types of cholangiocarcinoma are intrahepatic and extrahepatic cholangiocarcinoma. Intrahepatic cholangiocarcinoma (ICC) is a rare and aggressive form of liver cancer that originates within the liver's bile ducts. Treatment options vary based on different product types, including capecitabine, 5-fluorouracil, oxaliplatin, gemcitabine, and cisplatin. Available therapies include targeted drug therapy, chemotherapy, and immunotherapy, which are administered through oral, subcutaneous, or intravenous routes. These treatments are distributed through hospital pharmacies, retail pharmacies, and e-commerce platforms.

The cholangiocarcinoma market research report is one of a series of new reports from The Business Research Company that provides cholangiocarcinoma market statistics, including the cholangiocarcinoma industry global market size, regional shares, competitors with the cholangiocarcinoma market share, detailed cholangiocarcinoma market segments, market trends, and opportunities, and any further data you may need to thrive in the cholangiocarcinoma industry. This cholangiocarcinoma market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.

The cholangiocarcinoma market size has grown rapidly in recent years. It will grow from $0.55 billion in 2024 to $0.63 billion in 2025 at a compound annual growth rate (CAGR) of 13.4%. The growth during the historic period can be credited to the increasing incidence of liver and bile duct cancers, rising awareness of rare cancers, a growing focus on personalized treatment, the expansion of immunotherapy approaches, and the rising geriatric population.

The cholangiocarcinoma market size is expected to see rapid growth in the next few years. It will grow to $1.02 billion in 2029 at a compound annual growth rate (CAGR) of 13.1%. The growth during the forecast period can be credited to the increasing adoption of precision medicine, rising healthcare expenditure, the growing prevalence of genetic testing, and the expanding popularity of retail pharmacies. Key trends include advancements in diagnostic techniques, the expansion of clinical trials, the integration of AI in diagnostics, innovations in drug delivery systems, and continued progress in drug development.

The increasing incidence of liver disease is expected to drive the growth of the cholangiocarcinoma market. Liver disease encompasses various conditions that impair the liver's function or structure, including hepatitis, cirrhosis, fatty liver disease, and liver cancer. The rising prevalence of liver disease is attributed to risk factors such as obesity, diabetes, alcohol consumption, and viral hepatitis infections. Chronic inflammation and cirrhosis, in particular, contribute to the development of cholangiocarcinoma by promoting bile duct damage and malignant cell transformation. For instance, in December 2024, the Office for Health Improvement and Disparities, a UK-based government agency, reported that premature deaths from alcoholic liver disease increased by 3.6% in 2023, reaching 5,984 cases compared to 5,776 in 2022. As a result, the rising incidence of liver disease is fueling growth in the cholangiocarcinoma market.

Leading companies in the cholangiocarcinoma market are focusing on innovative treatments, such as targeted therapies, to improve patient outcomes. Targeted therapies are designed to act on specific genes, proteins, or molecules that drive cancer growth. By blocking these processes, targeted therapies can slow tumor progression, minimize side effects, and enhance treatment effectiveness. For instance, in August 2023, Taiho Pharmaceutical Co. Ltd., a Japan-based pharmaceutical company, introduced LYTGOBI (futibatinib), an FGFR inhibitor, for the treatment of unresectable biliary tract cancer with FGFR2 gene fusions. LYTGOBI selectively and irreversibly inhibits FGFR signaling, helping to slow tumor growth and improve patient outcomes in cholangiocarcinoma cases that have progressed after chemotherapy.

In July 2023, Lucence, a US-based precision health company, partnered with Innovent Biologics Inc. to enhance bile duct cancer diagnostics. As part of this collaboration, Innovent sponsored Lucence's LiquidMARK Bile Duct test for eligible patients in Hong Kong, aiming to improve diagnostic accuracy and expand treatment options. Innovent Biologics Inc. is a China-based biotechnology company specializing in innovative therapies, including treatments for cholangiocarcinoma. This partnership underscores the growing focus on precision diagnostics to enhance early detection and personalized treatment strategies in the cholangiocarcinoma market.

Major players in the cholangiocarcinoma market are F. Hoffmann-La Roche Ltd, Merck & Co. Inc., AbbVie Inc., Bristol-Myers Squibb Company, AstraZeneca PLC, Novartis AG, Takeda Pharmaceutical Company Limited, Eli Lilly and Company, Boston Scientific Corporation, Servier Laboratories, Incyte Corporation, Exelixis Inc., Hutchison China MediTech Limited, Zymeworks Inc., Agios Pharmaceuticals Inc., RenovoRx Inc., Specialised Therapeutics Pty Ltd, Ascletis Pharma Inc., Tiziana Life Sciences Ltd., and Taiho Pharmaceutical Co. Ltd.

North America was the largest region in the cholangiocarcinoma market in 2024. The regions covered in cholangiocarcinoma report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

The countries covered in the cholangiocarcinoma market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.

The cholangiocarcinoma market consists of revenues earned by entities by providing services such as diagnostic testing and imaging, surgical services, and supportive treatments to manage symptoms and improve patient outcomes. The market value includes the value of related goods sold by the service provider or included within the service offering. The cholangiocarcinoma market also includes sales of advanced imaging systems, molecular diagnostic tests, and drugs. Values in this market are 'factory gate' values, that is, the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors, and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).

The revenues for a specified geography are consumption values and are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

Cholangiocarcinoma Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.

This report focuses on cholangiocarcinoma market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.

Reasons to Purchase

Where is the largest and fastest growing market for cholangiocarcinoma ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward? The cholangiocarcinoma market global report from the Business Research Company answers all these questions and many more.

The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.

The forecasts are made after considering the major factors currently impacting the market. These include the Russia-Ukraine war, rising inflation, higher interest rates, and the legacy of the COVID-19 pandemic.

Scope

Table of Contents

1. Executive Summary

2. Cholangiocarcinoma Market Characteristics

3. Cholangiocarcinoma Market Trends And Strategies

4. Cholangiocarcinoma Market - Macro Economic Scenario Macro Economic Scenario Including The Impact Of Interest Rates, Inflation, Geopolitics And Covid And Recovery On The Market

5. Global Cholangiocarcinoma Growth Analysis And Strategic Analysis Framework

6. Cholangiocarcinoma Market Segmentation

7. Cholangiocarcinoma Market Regional And Country Analysis

8. Asia-Pacific Cholangiocarcinoma Market

9. China Cholangiocarcinoma Market

10. India Cholangiocarcinoma Market

11. Japan Cholangiocarcinoma Market

12. Australia Cholangiocarcinoma Market

13. Indonesia Cholangiocarcinoma Market

14. South Korea Cholangiocarcinoma Market

15. Western Europe Cholangiocarcinoma Market

16. UK Cholangiocarcinoma Market

17. Germany Cholangiocarcinoma Market

18. France Cholangiocarcinoma Market

19. Italy Cholangiocarcinoma Market

20. Spain Cholangiocarcinoma Market

21. Eastern Europe Cholangiocarcinoma Market

22. Russia Cholangiocarcinoma Market

23. North America Cholangiocarcinoma Market

24. USA Cholangiocarcinoma Market

25. Canada Cholangiocarcinoma Market

26. South America Cholangiocarcinoma Market

27. Brazil Cholangiocarcinoma Market

28. Middle East Cholangiocarcinoma Market

29. Africa Cholangiocarcinoma Market

30. Cholangiocarcinoma Market Competitive Landscape And Company Profiles

31. Cholangiocarcinoma Market Other Major And Innovative Companies

32. Global Cholangiocarcinoma Market Competitive Benchmarking And Dashboard

33. Key Mergers And Acquisitions In The Cholangiocarcinoma Market

34. Recent Developments In The Cholangiocarcinoma Market

35. Cholangiocarcinoma Market High Potential Countries, Segments and Strategies

36. Appendix

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