In-vitro transcription templates are specific DNA sequences crafted to guide RNA synthesis under controlled laboratory conditions. These templates feature designated promoter regions recognized by RNA polymerase, enabling the efficient production of RNA molecules for diverse applications such as research, diagnostic advancements, and therapeutic development. They serve as reliable and precise resources for RNA synthesis, supporting activities in molecular biology and genetic investigations.
The primary applications of in-vitro transcription templates are in vaccine development and therapeutic production. Integral multi-tandem valves represent a category of single-unit valves that consolidate multiple control functions into a compact body. These valves find utility across various research stages including exploratory and clinical phases in treating ailments such as cancer, infectious diseases, lifestyle disorders, genetic conditions, and other medical conditions. They are utilized by pharmaceutical and biotechnology firms, contract research organizations (CROs) and contract manufacturing organizations (CMOs), academic and research institutions, and other relevant entities.
The in-vitro transcription templates market research report is one of a series of new reports from The Business Research Company that provides in-vitro transcription templates market statistics, including the in-vitro transcription templates industry global market size, regional shares, competitors with in-vitro transcription templates market share, detailed in-vitro transcription templates market segments, market trends, and opportunities, and any further data you may need to thrive in the in-vitro transcription templates industry. These in-vitro transcription templates market research reports deliver a complete perspective of everything you need, with an in-depth analysis of the current and future scenarios of the industry.
The in-vitro transcription templates market size has grown exponentially in recent years. It will grow from $1.01 billion in 2024 to $1.25 billion in 2025 at a compound annual growth rate (CAGR) of 23.7%. The growth in the historic period can be attributed to rise in cases of chronic diseases, increase in investments in R&D in healthcare and pharmaceutical sectors, improvements in gene therapy technology, collaborations and partnerships and developments in gene therapy.
The in-vitro transcription templates market size is expected to see exponential growth in the next few years. It will grow to $2.9 billion in 2029 at a compound annual growth rate (CAGR) of 23.4%. The growth in the forecast period can be attributed to Increase in advancement in biotechnology, rise in focus in R&D activities, rise in usage of in-vitro transcription templates, demand for early diagnosis of diseases and increasing need for mRNA-based vaccines. Major trends in the forecast period include developments in RNA synthesis technologies, technological advancements, advancement in biotechnology, advancements in enzymatic synthesis techniques, and integration of automation and digitalization.
The rise in gene therapy's prominence is anticipated to drive growth in the in-vitro transcription templates market. Gene therapy involves modifying cellular genes to treat or prevent illnesses by rectifying defective genes. Technological advancements such as CRISPR, substantial investments, and recent treatment successes have heightened interest in this approach. In-vitro transcription templates play a crucial role in gene therapy by providing the necessary RNA molecules for mRNA-based therapies, siRNA-based therapies, and gene editing technologies, enabling the treatment of genetic disorders and diseases. For instance, as of March 2024, the Food and Drug Administration (FDA), a US-based federal agency under the Department of Health and Human Services, reported approving 36 gene therapies, with another 500 in the pipeline. They expect to approve 10-20 annually by 2025, further emphasizing the growing focus on gene therapy driving the in-vitro transcription templates market's expansion.
Key players in the in-vitro transcription templates market are actively developing self-amplifying RNA synthesis services to enhance RNA-based therapy efficiency and effectiveness, reduce production costs, and improve patient outcomes across various therapeutic applications. This technology allows RNA production capable of self-replication within host cells, leading to heightened protein expression from minimal RNA input, thereby improving RNA-based therapy efficiency and effectiveness. For example, in May 2024, GenScript Biotech Corporation, a US-based biotechnology firm, unveiled a self-amplifying RNA (saRNA) synthesis service, expanding its in-vitro transcription RNA synthesis offerings. This new service boosts the potency and efficacy of vaccines, immunotherapies, and gene therapies by enabling robust protein expression from small RNA quantities. The saRNA platform aims to decrease dosages, lower production costs, and enhance patient outcomes, supported by extensive research and development ensuring high purity and improved protein expression.
In September 2022, Lonza, a Switzerland-based pharmaceutical and biotechnology company, partnered with Torchlight to incorporate Touchlight's innovative doggybone DNA (dbDNA) technology into its mRNA development and manufacturing services. This collaboration broadens Lonza's customer offerings, providing faster, scalable, and purer alternatives to traditional plasmid DNA (pDNA) methods, strengthening Lonza's integrated mRNA manufacturing capabilities. Torchlight, a UK-based biotechnology firm, specializes in DNA production and development through an enzymatic process.
Major companies operating in the in-vitro transcription templates market are Thermo Fisher Scientific Inc., Danaher Corporation, Merck KGaA, Eurofins Genomics LLC, Agilent Technologies Inc., Illumina Inc., Bio-Rad Laboratories Inc., Qiagen N.V., Integrated DNA Technologies Inc., Promega Corporation, Genescript Biotech Corporation, Takara Bio Inc., New England Biolabs, OriGene Technologies Inc., Cayman Chemical, Synthego Corporation, Synbio Technologies, Creative Diagnostics, VectorBuilder Inc., Bio-Synthesis Inc., TriLink BioTechnologies, Norgen Biotek Corporation, Genaxxon BioScience GmbH, Enzo Life Sciences Inc., GeneCopoeia
North America was the largest region in the in-vitro transcription templates market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the in-vitro transcription templates market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
The countries covered in the in-vitro transcription templates market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
The in-vitro transcription templates market consists of revenues earned by entities by providing services such as RNA synthesis, quality control services, scale-up production, and technical support. The market value includes the value of related goods sold by the service provider or included within the service offering. The in-vitro transcription templates market also includes sales of DNA plasmids, linearized DNA, and synthetic oligonucleotides. Values in this market are 'factory gate' values, that is the value of goods sold by the manufacturers or creators of the goods, whether to other entities (including downstream manufacturers, wholesalers, distributors and retailers) or directly to end customers. The value of goods in this market includes related services sold by the creators of the goods.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
In-Vitro Transcription Templates Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.
This report focuses on in-vitro transcription templates market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
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Where is the largest and fastest growing market for in-vitro transcription templates ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward? The in-vitro transcription templates market global report from the Business Research Company answers all these questions and many more.
The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.
The market characteristics section of the report defines and explains the market.
The market size section gives the market size ($b) covering both the historic growth of the market, and forecasting its development.
The forecasts are made after considering the major factors currently impacting the market. These include:
The forecasts are made after considering the major factors currently impacting the market. These include the Russia-Ukraine war, rising inflation, higher interest rates, and the legacy of the COVID-19 pandemic.
Market segmentations break down the market into sub markets.
The regional and country breakdowns section gives an analysis of the market in each geography and the size of the market by geography and compares their historic and forecast growth. It covers the growth trajectory of COVID-19 for all regions, key developed countries and major emerging markets.
The competitive landscape chapter gives a description of the competitive nature of the market, market shares, and a description of the leading companies. Key financial deals which have shaped the market in recent years are identified.
The trends and strategies section analyses the shape of the market as it emerges from the crisis and suggests how companies can grow as the market recovers.
Scope
Markets Covered:1) By Treatment: Vaccine; Therapeutic
2) By Research Stage: Exploratory; Clinical
3) By Disease: Cancer; Infectious Disease; Lifestyle Disease; Genetic Disease; Other Diseases
4) By End User: Pharmaceutical And Biotechnology Companies; Contract Research Organizations (CROs) And Contract Manufacturing Organizations (CMOs); Academics And Research; Other End Users
Subsegments:
1) By Vaccine: MRNA Vaccines; DNA Vaccines
2) By Therapeutic: Gene Therapy; RNA-Based Therapeutics
3. In-Vitro Transcription Templates Market Trends And Strategies
4. In-Vitro Transcription Templates Market - Macro Economic Scenario Including The Impact Of Interest Rates, Inflation, Geopolitics, Covid And Recovery On The Market
5. Global In-Vitro Transcription Templates Growth Analysis And Strategic Analysis Framework
5.1. Global In-Vitro Transcription Templates PESTEL Analysis (Political, Social, Technological, Environmental and Legal Factors, Drivers and Restraints)
5.2. Analysis Of End Use Industries
5.3. Global In-Vitro Transcription Templates Market Growth Rate Analysis
5.4. Global In-Vitro Transcription Templates Historic Market Size and Growth, 2019 - 2024, Value ($ Billion)
5.5. Global In-Vitro Transcription Templates Forecast Market Size and Growth, 2024 - 2029, 2034F, Value ($ Billion)
5.6. Global In-Vitro Transcription Templates Total Addressable Market (TAM)
6.1. Global In-Vitro Transcription Templates Market, Segmentation By Treatment, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
Vaccine
Therapeutic
6.2. Global In-Vitro Transcription Templates Market, Segmentation By Research Stage, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
Exploratory
Clinical
6.3. Global In-Vitro Transcription Templates Market, Segmentation By Disease, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
Cancer
Infectious Disease
Lifestyle Disease
Genetic Disease
Other Diseases
6.4. Global In-Vitro Transcription Templates Market, Segmentation By End User, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
Pharmaceutical And Biotechnology Companies
Contract Research Organizations (CROs) And Contract Manufacturing Organizations (CMOs)
Academics And Research
Other End Users
6.5. Global In-Vitro Transcription Templates Market, Sub-Segmentation Of Vaccine, By Type, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
MRNA Vaccines
DNA Vaccines
6.6. Global In-Vitro Transcription Templates Market, Sub-Segmentation Of Therapeutic, By Type, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
Gene Therapy
RNA-Based Therapeutics
7. In-Vitro Transcription Templates Market Regional And Country Analysis
7.1. Global In-Vitro Transcription Templates Market, Split By Region, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
7.2. Global In-Vitro Transcription Templates Market, Split By Country, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
Region Information, Market Information, Background Information, Government Initiatives, Regulations, Regulatory Bodies, Major Associations, Taxes Levied, Corporate Tax Structure, Investments, Major Companies
8.2. Asia-Pacific In-Vitro Transcription Templates Market, Segmentation By Treatment, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
8.3. Asia-Pacific In-Vitro Transcription Templates Market, Segmentation By Research Stage, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
8.4. Asia-Pacific In-Vitro Transcription Templates Market, Segmentation By Disease, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
9. China In-Vitro Transcription Templates Market
9.1. China In-Vitro Transcription Templates Market Overview
9.2. China In-Vitro Transcription Templates Market, Segmentation By Treatment, Historic and Forecast, 2019-2024, 2024-2029F, 2034F,$ Billion
9.3. China In-Vitro Transcription Templates Market, Segmentation By Research Stage, Historic and Forecast, 2019-2024, 2024-2029F, 2034F,$ Billion
9.4. China In-Vitro Transcription Templates Market, Segmentation By Disease, Historic and Forecast, 2019-2024, 2024-2029F, 2034F,$ Billion
10. India In-Vitro Transcription Templates Market
10.1. India In-Vitro Transcription Templates Market, Segmentation By Treatment, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
10.2. India In-Vitro Transcription Templates Market, Segmentation By Research Stage, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
10.3. India In-Vitro Transcription Templates Market, Segmentation By Disease, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
11. Japan In-Vitro Transcription Templates Market
11.1. Japan In-Vitro Transcription Templates Market Overview
11.2. Japan In-Vitro Transcription Templates Market, Segmentation By Treatment, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
11.3. Japan In-Vitro Transcription Templates Market, Segmentation By Research Stage, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
11.4. Japan In-Vitro Transcription Templates Market, Segmentation By Disease, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
12. Australia In-Vitro Transcription Templates Market
12.1. Australia In-Vitro Transcription Templates Market, Segmentation By Treatment, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
12.2. Australia In-Vitro Transcription Templates Market, Segmentation By Research Stage, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
12.3. Australia In-Vitro Transcription Templates Market, Segmentation By Disease, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
13. Indonesia In-Vitro Transcription Templates Market
13.1. Indonesia In-Vitro Transcription Templates Market, Segmentation By Treatment, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
13.2. Indonesia In-Vitro Transcription Templates Market, Segmentation By Research Stage, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
13.3. Indonesia In-Vitro Transcription Templates Market, Segmentation By Disease, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
14. South Korea In-Vitro Transcription Templates Market
14.1. South Korea In-Vitro Transcription Templates Market Overview
14.2. South Korea In-Vitro Transcription Templates Market, Segmentation By Treatment, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
14.3. South Korea In-Vitro Transcription Templates Market, Segmentation By Research Stage, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
14.4. South Korea In-Vitro Transcription Templates Market, Segmentation By Disease, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
15. Western Europe In-Vitro Transcription Templates Market
15.1. Western Europe In-Vitro Transcription Templates Market Overview
15.2. Western Europe In-Vitro Transcription Templates Market, Segmentation By Treatment, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
15.3. Western Europe In-Vitro Transcription Templates Market, Segmentation By Research Stage, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
15.4. Western Europe In-Vitro Transcription Templates Market, Segmentation By Disease, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
16. UK In-Vitro Transcription Templates Market
16.1. UK In-Vitro Transcription Templates Market, Segmentation By Treatment, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
16.2. UK In-Vitro Transcription Templates Market, Segmentation By Research Stage, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
16.3. UK In-Vitro Transcription Templates Market, Segmentation By Disease, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
17.1. Germany In-Vitro Transcription Templates Market, Segmentation By Treatment, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
17.2. Germany In-Vitro Transcription Templates Market, Segmentation By Research Stage, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
17.3. Germany In-Vitro Transcription Templates Market, Segmentation By Disease, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
18. France In-Vitro Transcription Templates Market
18.1. France In-Vitro Transcription Templates Market, Segmentation By Treatment, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
18.2. France In-Vitro Transcription Templates Market, Segmentation By Research Stage, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
18.3. France In-Vitro Transcription Templates Market, Segmentation By Disease, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
19. Italy In-Vitro Transcription Templates Market
19.1. Italy In-Vitro Transcription Templates Market, Segmentation By Treatment, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
19.2. Italy In-Vitro Transcription Templates Market, Segmentation By Research Stage, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
19.3. Italy In-Vitro Transcription Templates Market, Segmentation By Disease, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
20. Spain In-Vitro Transcription Templates Market
20.1. Spain In-Vitro Transcription Templates Market, Segmentation By Treatment, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
20.2. Spain In-Vitro Transcription Templates Market, Segmentation By Research Stage, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
20.3. Spain In-Vitro Transcription Templates Market, Segmentation By Disease, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
21. Eastern Europe In-Vitro Transcription Templates Market
21.1. Eastern Europe In-Vitro Transcription Templates Market Overview
21.2. Eastern Europe In-Vitro Transcription Templates Market, Segmentation By Treatment, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
21.3. Eastern Europe In-Vitro Transcription Templates Market, Segmentation By Research Stage, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
21.4. Eastern Europe In-Vitro Transcription Templates Market, Segmentation By Disease, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
22. Russia In-Vitro Transcription Templates Market
22.1. Russia In-Vitro Transcription Templates Market, Segmentation By Treatment, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
22.2. Russia In-Vitro Transcription Templates Market, Segmentation By Research Stage, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
22.3. Russia In-Vitro Transcription Templates Market, Segmentation By Disease, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
23. North America In-Vitro Transcription Templates Market
23.1. North America In-Vitro Transcription Templates Market Overview
23.2. North America In-Vitro Transcription Templates Market, Segmentation By Treatment, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
23.3. North America In-Vitro Transcription Templates Market, Segmentation By Research Stage, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
23.4. North America In-Vitro Transcription Templates Market, Segmentation By Disease, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
24. USA In-Vitro Transcription Templates Market
24.1. USA In-Vitro Transcription Templates Market Overview
24.2. USA In-Vitro Transcription Templates Market, Segmentation By Treatment, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
24.3. USA In-Vitro Transcription Templates Market, Segmentation By Research Stage, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
24.4. USA In-Vitro Transcription Templates Market, Segmentation By Disease, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
25.2. Canada In-Vitro Transcription Templates Market, Segmentation By Treatment, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
25.3. Canada In-Vitro Transcription Templates Market, Segmentation By Research Stage, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
25.4. Canada In-Vitro Transcription Templates Market, Segmentation By Disease, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
26. South America In-Vitro Transcription Templates Market
26.1. South America In-Vitro Transcription Templates Market Overview
26.2. South America In-Vitro Transcription Templates Market, Segmentation By Treatment, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
26.3. South America In-Vitro Transcription Templates Market, Segmentation By Research Stage, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
26.4. South America In-Vitro Transcription Templates Market, Segmentation By Disease, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
27. Brazil In-Vitro Transcription Templates Market
27.1. Brazil In-Vitro Transcription Templates Market, Segmentation By Treatment, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
27.2. Brazil In-Vitro Transcription Templates Market, Segmentation By Research Stage, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
27.3. Brazil In-Vitro Transcription Templates Market, Segmentation By Disease, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
28. Middle East In-Vitro Transcription Templates Market
28.1. Middle East In-Vitro Transcription Templates Market Overview
28.2. Middle East In-Vitro Transcription Templates Market, Segmentation By Treatment, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
28.3. Middle East In-Vitro Transcription Templates Market, Segmentation By Research Stage, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
28.4. Middle East In-Vitro Transcription Templates Market, Segmentation By Disease, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
29. Africa In-Vitro Transcription Templates Market
29.1. Africa In-Vitro Transcription Templates Market Overview
29.2. Africa In-Vitro Transcription Templates Market, Segmentation By Treatment, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
29.3. Africa In-Vitro Transcription Templates Market, Segmentation By Research Stage, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
29.4. Africa In-Vitro Transcription Templates Market, Segmentation By Disease, Historic and Forecast, 2019-2024, 2024-2029F, 2034F, $ Billion
30. In-Vitro Transcription Templates Market Competitive Landscape And Company Profiles