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High-Performance Liquid Chromatography Global Market Report 2025
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High-performance liquid chromatography (HPLC) is a technique employed to separate, identify, and quantify the components within a mixture. It plays a crucial role in the quantitative determination of plasma levels of drugs and their metabolites, particularly in the development of novel medications and therapy monitoring.

The primary products associated with high-performance liquid chromatography include instruments, consumables, accessories, and software. HPLC instrumentation typically comprises nine basic components, incorporating data collection, an output system, and connective tubing and fittings. These components find application in various fields such as clinical research, diagnostics, forensics, and others. The technology is utilized by diverse end-users, including pharmaceutical and biotechnology companies, academic and research institutes, food and beverage companies, hospitals and clinics, environmental agencies, and other entities.

The high-performance liquid chromatography market research report is one of a series of new reports from The Business Research Company that provides high-performance liquid chromatography market statistics, including high-performance liquid chromatography industry global market size, regional shares, competitors with a high-performance liquid chromatography market share, detailed high-performance liquid chromatography market segments, market trends and opportunities, and any further data you may need to thrive in the high-performance liquid chromatography industry. This high-performance liquid chromatography market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.

The high-performance liquid chromatography market size has grown strongly in recent years. It will grow from $6.28 billion in 2024 to $6.79 billion in 2025 at a compound annual growth rate (CAGR) of 8.0%. The growth in the historic period can be attributed to increase in pharmaceutical research, rise in food and beverage analysis, rise in demand from environmental testing, increase in increased use in clinical diagnostics, rise in research and development.

The high-performance liquid chromatography market size is expected to see rapid growth in the next few years. It will grow to $10.59 billion in 2029 at a compound annual growth rate (CAGR) of 11.8%. The growth in the forecast period can be attributed to increasing drug safety and quality assurance, demand from precision medicine, expansion of cannabis testing, increasing environmental monitoring, increasing method development. Major trends in the forecast period include advanced detectors, high-throughput hplc, green and sustainable hplc, uhplc adoption, lc-ms integration.

An increase in the prevalence of chronic diseases is anticipated to drive the growth of the high-performance liquid chromatography (HPLC) market moving forward. Chronic diseases, including cancer, heart disease, stroke, diabetes, and arthritis, are conditions that typically persist for extended periods and require ongoing medical care. HPLC is used to analyze medications to verify their identity, provide quantitative data, and monitor the effectiveness of disease treatment. It can also enhance the understanding of both normal and pathological processes in the human body through biological and therapeutic research before drug approval, thereby contributing to market growth. For example, in 2022, the American Cancer Society, a U.S.-based voluntary organization, estimated that there would be approximately 1.9 million new cancer cases diagnosed and 609,360 cancer deaths in the United States. Additionally, a report from the International Diabetes Federation (IDF), published in December 2021, indicated that around 537 million individuals aged 20 to 79 were estimated to have diabetes in 2021, with projections of 643 million by 2030 and 783 million by 2045. Thus, the rising prevalence of chronic diseases is driving the expansion of the high-performance liquid chromatography market.

An increasing number of ongoing clinical trials is expected to drive the growth of the high-performance liquid chromatography (HPLC) market in the future. Clinical trials are research studies conducted with human participants to assess the safety and effectiveness of new medical treatments, interventions, or diagnostic procedures. HPLC plays a crucial role in clinical trials by delivering precise analyses of pharmaceutical compounds and biomarkers, ensuring drug safety and efficacy. It aids in quality control, pharmacokinetic studies, and biomarker quantification, supporting drug development and enhancing patient safety. For example, in October 2023, ClinicalTrials.gov, a component of the National Institutes of Health (NIH), a U.S.-based government agency responsible for conducting and supporting medical research, reported an increase in registered studies from 437,523 in 2022 to 468,457 across all 50 states and 221 countries. Additionally, it was noted that 143,613 studies (31% of the total) are registered in the U.S., while 251,159 studies (54% of the total) are registered outside the U.S. Therefore, the growing number of ongoing clinical trials is driving the expansion of the high-performance liquid chromatography market.

Key companies in the market are developing advanced high-performance liquid chromatography (HPLC) technologies, such as integrated HPLC, for various research applications. For example, in April 2024, Waters Corporation, a U.S.-based life sciences firm, introduced the Alliance iS Bio. This system is specifically designed for biopharmaceutical applications, ensuring precise and reliable separation of complex biological molecules. It features smart technology that aids quality control analysts, thereby reducing operational errors and enhancing system performance. The system addresses up to 40% of common errors, which minimizes the time spent investigating failed runs and out-of-spec results. By improving workflow efficiency, it allows for faster and more accurate results in biopharma quality control processes.

Major players in the high-performance liquid chromatography market are intensifying their focus on introducing cutting-edge systems to gain a competitive advantage. Waters Corporation, a leading US-based manufacturer of laboratory instruments, exemplifies this trend with the launch of the next-generation Alliance iS High-Performance Liquid Chromatography (HPLC) System in March 2023. This intelligent and advanced instrument is tailored to meet the distinctive needs of quality control (QC) laboratories. The Alliance iS HPLC System is engineered to reduce laboratory errors by up to 40%, featuring enhanced temperature control in the sample manager, column manager, and detector, making it adaptable to global requirements. Noteworthy features include tool-free fittings, clearly labeled and organized solvent lines, and auto-recognition of Waters eConnect HPLC columns to prevent leaks and user errors during setup. The system is designed with intuitive mechanisms for fast feedback, a touchscreen interface for troubleshooting and maintenance guidance, and optimized accessibility to serviceable components, ensuring efficient operation and maximizing return on investment.

In July 2024, Catalyze Partners, a U.S.-based firm focused on transforming innovative technologies, acquired Axcend, LLC, for an undisclosed sum. This acquisition enhances Catalyze Partners' capacity to address the growing demand for advanced analytical solutions in sectors such as pharmaceuticals, environmental monitoring, and chemical manufacturing. Axcend, LLC, is a U.S.-based company specializing in high-performance liquid chromatography systems.

Major companies operating in the high-performance liquid chromatography market include Waters Corporation, Agilent Technologies Inc., Shimadzu Corporation, Thermo Fisher Scientific Inc., PerkinElmer Inc., Bio-Rad Laboratories Inc., Merck Millipore, Hitachi Ltd., Phenomenex Inc., JASCO Corporation, Gilson Inc., Knauer GmbH, SIELC Technologies, Tosoh Bioscience LLC, YMC Co. Ltd., GL Sciences Inc., Sepax Technologies Inc., Restek Corporation, Hamilton Company, ACE HPLC Columns, Advanced Chromatography Technologies Ltd., Analytical Sales and Services Inc., Chromatography Research Supplies Inc., Daicel Corporation, Eksigent Technologies LLC, Hichrom Limited

North America was the largest region in the high-performance liquid chromatography market analysis in 2024. Asia-Pacific is expected to be the fastest-growing region in the global high performance liquid chromatography market during the forecast period. The regions covered in the global high performance liquid chromatography market share report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

The countries covered in the high-performance liquid chromatography market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK and USA.

The high-performance liquid chromatography market includes revenues earned by entities by providing reverse phase columns, normal phase columns, ion exchange columns, and size exclusion columns. The market value includes the value of related goods sold by the service provider or included within the service offering. Only goods and services traded between entities or sold to end consumers are included.

The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD unless otherwise specified).

The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.

High-Performance Liquid Chromatography Global Market Report 2025 from The Business Research Company provides strategists, marketers and senior management with the critical information they need to assess the market.

This report focuses on high-performance liquid chromatography market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.

Reasons to Purchase

Where is the largest and fastest growing market for high-performance liquid chromatography ? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward? The high-performance liquid chromatography market global report from the Business Research Company answers all these questions and many more.

The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market's historic and forecast market growth by geography.

The forecasts are made after considering the major factors currently impacting the market. These include the Russia-Ukraine war, rising inflation, higher interest rates, and the legacy of the COVID-19 pandemic.

Scope

Table of Contents

1. Executive Summary

2. High-Performance Liquid Chromatography Market Characteristics

3. High-Performance Liquid Chromatography Market Trends And Strategies

4. High-Performance Liquid Chromatography Market - Macro Economic Scenario Including The Impact Of Interest Rates, Inflation, Geopolitics And Covid And Recovery On The Market

5. Global High-Performance Liquid Chromatography Growth Analysis And Strategic Analysis Framework

6. High-Performance Liquid Chromatography Market Segmentation

7. High-Performance Liquid Chromatography Market Regional And Country Analysis

8. Asia-Pacific High-Performance Liquid Chromatography Market

9. China High-Performance Liquid Chromatography Market

10. India High-Performance Liquid Chromatography Market

11. Japan High-Performance Liquid Chromatography Market

12. Australia High-Performance Liquid Chromatography Market

13. Indonesia High-Performance Liquid Chromatography Market

14. South Korea High-Performance Liquid Chromatography Market

15. Western Europe High-Performance Liquid Chromatography Market

16. UK High-Performance Liquid Chromatography Market

17. Germany High-Performance Liquid Chromatography Market

18. France High-Performance Liquid Chromatography Market

19. Italy High-Performance Liquid Chromatography Market

20. Spain High-Performance Liquid Chromatography Market

21. Eastern Europe High-Performance Liquid Chromatography Market

22. Russia High-Performance Liquid Chromatography Market

23. North America High-Performance Liquid Chromatography Market

24. USA High-Performance Liquid Chromatography Market

25. Canada High-Performance Liquid Chromatography Market

26. South America High-Performance Liquid Chromatography Market

27. Brazil High-Performance Liquid Chromatography Market

28. Middle East High-Performance Liquid Chromatography Market

29. Africa High-Performance Liquid Chromatography Market

30. High-Performance Liquid Chromatography Market Competitive Landscape And Company Profiles

31. High-Performance Liquid Chromatography Market Other Major And Innovative Companies

32. Global High-Performance Liquid Chromatography Market Competitive Benchmarking And Dashboard

33. Key Mergers And Acquisitions In The High-Performance Liquid Chromatography Market

34. Recent Developments In The High-Performance Liquid Chromatography Market

35. High-Performance Liquid Chromatography Market High Potential Countries, Segments and Strategies

36. Appendix

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