Global Biological Skin Substitutes Market Size, Share & Trends Analysis Report By Type, By End Use, By Application, By Regional Outlook and Forecast, 2024 - 2031
The Global Biological Skin Substitutes Market size is expected to reach $568.3 billion by 2031, rising at a market growth of 8.6% CAGR during the forecast period.
The North American market for biological skin substitutes leads globally, propelled by advanced healthcare infrastructure, significant investment in R&D, and a high prevalence of chronic wounds and burn injuries. Additionally, rising awareness about advanced wound care therapies and the continuous introduction of innovative products contribute to the segment's growth, making North America the dominant region for biological skin substitutes. Thus, the North America segment procured 40% revenue share in the biological skin substitutes market in 2023.
Chronic wounds, such as diabetic foot ulcers, venous leg ulcers, and pressure ulcers, are often challenging to heal due to underlying health conditions like diabetes, poor circulation, and prolonged immobility. It is anticipated that 1 to 2 percent of the population in developed countries will endure a chronic wound at some point in their lives. Additionally, Reconstructive surgeries, often performed after trauma, burn injuries, cancer treatments, or congenital disabilities, also drive the demand for biological skin substitutes. Many patients undergoing reconstructive surgery require skin grafts to restore skin loss due to injury or illness, and biological substitutes offer an effective solution by promoting natural healing and minimizing visible scarring. Reconstructive surgeries, often performed after trauma, burn injuries, cancer treatments, or congenital disabilities, also drive the demand for biological skin substitutes. Many patients undergoing reconstructive surgery require skin grafts to restore skin loss due to injury or illness, and biological substitutes offer an effective solution by promoting natural healing and minimizing visible scarring.
However, biological skin substitutes significantly advance wound care and skin regeneration, providing a promising solution for burn victims and individuals with chronic wounds. However, one of the primary barriers to their widespread adoption is the high cost associated with these products. Developing biological skin substitutes requires sophisticated, cost-intensive manufacturing processes, including the harvesting, processing, and preserving of human or animal-derived tissues. Hence, the high cost of biological skin substitutes restricts their accessibility, limiting their impact on global health outcomes in wound care and skin regeneration.
Type Outlook
Based on type, the market is bifurcated into human donor tissue-derived products and acellular animal-derived products. The human donor tissue-derived products segment garnered 64% revenue share in the market in 2023. This segment leads the market due to its high compatibility and acceptance rates within the human body, which results in improved healing outcomes.
End Use Outlook
On the basis of end use, the market is classified into hospitals, outpatient facilities, and research & manufacturing. The hospitals segment acquired 53% revenue share in the market in 2023. This prominence is attributed to hospitals' comprehensive infrastructure and specialized medical personnel, enabling them to effectively manage complex wound care cases.
Application Outlook
By application, the market is divided into acute wounds and chronic wounds. The chronic wounds segment garnered 47% revenue share in the market in 2023. These wounds are often challenging to heal and require long-term management strategies. Biological skin substitutes offer effective solutions by providing a conducive environment for tissue regeneration and reducing healing time.
Regional Outlook
Region-wise, the market is analyzed across North America, Europe, Asia Pacific, and LAMEA. The Europe segment acquired 30% revenue share in the market in 2023. The European market is driven by increasing awareness of advanced wound care solutions, a growing elderly population susceptible to chronic wounds, and proactive government initiatives supporting healthcare advancements.
List of Key Companies Profiled
Smith & Nephew plc
Stryker Corporation
MIMEDX Group, Inc.
Organogenesis Holdings, Inc.
Integra LifeSciences Corporation
3M Company
Essity AB (BSN Medical)
Zimmer Biomet Holdings, Inc.
Vericel Corporation
Molnlycke Health Care AB
Global Biological Skin Substitutes Market Report Segmentation
By Type
Human Donor Tissue-derived Products
Acellular Animal-derived Products
By End Use
Hospitals
Outpatient Facilities
Research & Manufacturing
By Application
Acute Wounds
Chronic Wounds
By Geography
North America
US
Canada
Mexico
Rest of North America
Europe
Germany
UK
France
Russia
Spain
Italy
Rest of Europe
Asia Pacific
China
Japan
India
South Korea
Singapore
Malaysia
Rest of Asia Pacific
LAMEA
Brazil
Argentina
UAE
Saudi Arabia
South Africa
Nigeria
Rest of LAMEA
Table of Contents
Chapter 1. Market Scope & Methodology
1.1 Market Definition
1.2 Objectives
1.3 Market Scope
1.4 Segmentation
1.4.1 Global Biological Skin Substitutes Market, by Type
1.4.2 Global Biological Skin Substitutes Market, by End Use
1.4.3 Global Biological Skin Substitutes Market, by Application
1.4.4 Global Biological Skin Substitutes Market, by Geography
1.5 Methodology for the research
Chapter 2. Market at a Glance
2.1 Key Highlights
Chapter 3. Market Overview
3.1 Introduction
3.1.1 Overview
3.1.1.1 Market Composition and Scenario
3.2 Key Factors Impacting the Market
3.2.1 Market Drivers
3.2.2 Market Restraints
3.2.3 Market Opportunities
3.2.4 Market Challenges
Chapter 4. Competition Analysis - Global
4.1 Market Share Analysis, 2023
4.2 Porter Five Forces Analysis
Chapter 5. Global Biological Skin Substitutes Market by Type
5.1 Global Human Donor Tissue-derived Products Market by Region
5.2 Global Acellular Animal-derived Products Market by Region
Chapter 6. Global Biological Skin Substitutes Market by End Use
6.1 Global Hospitals Market by Region
6.2 Global Outpatient Facilities Market by Region
6.3 Global Research & Manufacturing Market by Region
Chapter 7. Global Biological Skin Substitutes Market by Application
7.1 Global Acute Wounds Market by Region
7.2 Global Chronic Wounds Market by Region
Chapter 8. Global Biological Skin Substitutes Market by Region
8.1 North America Biological Skin Substitutes Market
8.1.1 North America Biological Skin Substitutes Market by Type
8.1.1.1 North America Human Donor Tissue-derived Products Market by Region
8.1.1.2 North America Acellular Animal-derived Products Market by Region
8.1.2 North America Biological Skin Substitutes Market by End Use
8.1.2.1 North America Hospitals Market by Country
8.1.2.2 North America Outpatient Facilities Market by Country
8.1.2.3 North America Research & Manufacturing Market by Country
8.1.3 North America Biological Skin Substitutes Market by Application
8.1.3.1 North America Acute Wounds Market by Country
8.1.3.2 North America Chronic Wounds Market by Country
8.1.4 North America Biological Skin Substitutes Market by Country
8.1.4.1 US Biological Skin Substitutes Market
8.1.4.1.1 US Biological Skin Substitutes Market by Type
8.1.4.1.2 US Biological Skin Substitutes Market by End Use
8.1.4.1.3 US Biological Skin Substitutes Market by Application
8.1.4.2 Canada Biological Skin Substitutes Market
8.1.4.2.1 Canada Biological Skin Substitutes Market by Type
8.1.4.2.2 Canada Biological Skin Substitutes Market by End Use
8.1.4.2.3 Canada Biological Skin Substitutes Market by Application
8.1.4.3 Mexico Biological Skin Substitutes Market
8.1.4.3.1 Mexico Biological Skin Substitutes Market by Type
8.1.4.3.2 Mexico Biological Skin Substitutes Market by End Use
8.1.4.3.3 Mexico Biological Skin Substitutes Market by Application
8.1.4.4 Rest of North America Biological Skin Substitutes Market
8.1.4.4.1 Rest of North America Biological Skin Substitutes Market by Type
8.1.4.4.2 Rest of North America Biological Skin Substitutes Market by End Use
8.1.4.4.3 Rest of North America Biological Skin Substitutes Market by Application
8.2 Europe Biological Skin Substitutes Market
8.2.1 Europe Biological Skin Substitutes Market by Type
8.2.1.1 Europe Human Donor Tissue-derived Products Market by Country
8.2.1.2 Europe Acellular Animal-derived Products Market by Country
8.2.2 Europe Biological Skin Substitutes Market by End Use
8.2.2.1 Europe Hospitals Market by Country
8.2.2.2 Europe Outpatient Facilities Market by Country
8.2.2.3 Europe Research & Manufacturing Market by Country
8.2.3 Europe Biological Skin Substitutes Market by Application
8.2.3.1 Europe Acute Wounds Market by Country
8.2.3.2 Europe Chronic Wounds Market by Country
8.2.4 Europe Biological Skin Substitutes Market by Country