The Global Huntington's Disease Treatment Market size is expected to reach $805.1 million by 2031, rising at a market growth of 9.0% CAGR during the forecast period.
The Asia-Pacific region's nations are investing in expanding and modernizing its hospitals, clinics, and specialized treatment facilities. Better facilities and access to healthcare enable HD patients to receive sophisticated treatment choices, interdisciplinary care, and early diagnosis. Consequently, the Asia pacific region would acquire nearly 25% of the total market share by 2031. Genetic diversity within the Asia Pacific region provides unique opportunities for studying Huntington's Disease genetics, disease variants, and population-specific factors influencing disease progression.
Huntington's disease is caused by a mutation in the HTT gene, which produces an abnormal form of the huntingtin protein. Moreover, RNA interference (RNAi) and antisense oligonucleotides (ASOs) are biotechnological approaches that can reduce the expression of the mutant HTT gene. Moreover, RNA interference (RNAi) and antisense oligonucleotides (ASOs) are biotechnological approaches that can reduce the expression of the mutant HTT gene. Additionally, Healthcare expenditure encompasses funding allocated to biomedical research, including neurodegenerative diseases like Huntington's disease. Furthermore, investments in healthcare infrastructure, such as specialized clinics, research centers, and laboratory facilities, are essential for advancing HD research and treatment. Therefore, rising healthcare expenditures and investments are propelling the market's growth.
However, A poisonous mutant huntingtin protein (mHTT) results from an HTT gene mutation that causes HD. This genetic mutation leads to neuronal dysfunction and eventual neurodegeneration. Moreover, the clinical manifestations of HD vary widely among individuals, both in terms of symptom onset and progression. Thus, complex disease pathophysiology is hampering the growth of the market.
The pandemic led to the suspension or delay of many clinical trials for Huntington's Disease due to lockdowns, travel restrictions, and the reallocation of healthcare resources to address COVID-19. In addition, the global supply chain disruptions caused by the pandemic affected the availability of medications and medical supplies for HD patients. Thus, the COVID-19 pandemic had a negative impact on the market.
Drug Type Outlook
Based on drug type, the Huntington's disease treatment market is divided into approved drugs and offlabel drugs. In 2023, the offlable drugs segment acquired 15.3% revenue share in the Huntington's disease treatment market. Off-label drugs may offer potential benefits in managing specific symptoms of Huntington's Disease, such as psychiatric symptoms (e.g., depression, anxiety), irritability, and cognitive impairment. Healthcare providers may explore off-label options to alleviate these challenging symptoms that significantly impact patient quality of life.
Distribution Channel Outlook
On the basis of distribution channel, the Huntington's disease treatment market is segmented into hospital pharmacies, drug stores & retail pharmacies, and online pharmacies. In 2023, the drug stores & retail pharmacies segment attained 32.7% revenue share in the Huntington's disease treatment market. Retail pharmacies stock a variety of medications used to manage symptoms associated with Huntington's Disease, including medications for chorea (involuntary movements), psychiatric symptoms (e.g., depression, anxiety), and cognitive impairments.
Age Outlook
By age, the Huntington's disease treatment market is bifurcated into below 50 years and above 50 years. The above 50 segment held 43.3% revenue share in the Huntington's disease treatment market in 2023. Huntington's Disease can present with subtle or atypical symptoms in older adults, leading to delays in diagnosis. As awareness and diagnostic capabilities improve, more individuals above 50 years old may receive a diagnosis of HD, prompting the initiation of treatment and management strategies to address symptoms and optimize quality of life.
Regional Outlook
Region-wise, the Huntington's disease treatment market is analyzed across North America, Europe, Asia Pacific, and LAMEA. The North America region witnessed 42% revenue share in the Huntington's disease treatment market in 2023. North America has a relatively higher Huntington's Disease prevalence than other regions. The disease is more commonly diagnosed among populations of European descent, which are prominent in North America. Also, the region is a global leader in biomedical research and pharmaceutical innovation.
List of Key Companies Profiled
Bausch Health Companies, Inc.
Teva Pharmaceutical Industries Ltd.
Camber Pharmaceuticals, Inc. (Hetero Labs Limited)
Hikma Pharmaceuticals PLC
Takeda Pharmaceutical Company Limited
Sun Pharmaceutical Industries Ltd.
Dr. Reddy's Laboratories Ltd.
Neurocrine Biosciences Inc.
Pfizer, Inc.
F. Hoffmann-La Roche Ltd.
Global Huntington's Disease Treatment Market Report Segmentation
By Drug Type
Approved Drugs
Tetrabenazine
Deutetrabenazine
Offlabel Drugs
By Distribution Channel
Hospital Pharmacies
Drug Store & Retail Pharmacies
Online Pharmacies
By Age
Below 50 years
Above 50 years
By Geography
North America
US
Canada
Mexico
Rest of North America
Europe
Germany
UK
France
Russia
Spain
Italy
Rest of Europe
Asia Pacific
China
Japan
India
South Korea
Singapore
Malaysia
Rest of Asia Pacific
LAMEA
Brazil
Argentina
UAE
Saudi Arabia
South Africa
Nigeria
Rest of LAMEA
Table of Contents
Chapter 1. Market Scope & Methodology
1.1 Market Definition
1.2 Objectives
1.3 Market Scope
1.4 Segmentation
1.4.1 Global Huntington's Disease Treatment Market, by Drug Type
1.4.2 Global Huntington's Disease Treatment Market, by Distribution Channel
1.4.3 Global Huntington's Disease Treatment Market, by Age
1.4.4 Global Huntington's Disease Treatment Market, by Geography
1.5 Methodology for the research
Chapter 2. Market at a Glance
2.1 Key Highlights
Chapter 3. Market Overview
3.1 Introduction
3.1.1 Overview
3.1.1.1 Market Composition and Scenario
3.2 Key Factors Impacting the Market
3.2.1 Market Drivers
3.2.2 Market Restraints
3.2.3 Market Opportunities
3.2.4 Market Challenges
3.3 Porter Five Forces Analysis
Chapter 4. Global Huntington's Disease Treatment Market by Drug Type
4.1 Global Approved Drugs Market by Region
4.2 Global Huntington's Disease Treatment Market by Approved Drugs Type
4.2.1 Global Tetrabenazine Market by Region
4.2.2 Global Deutetrabenazine Market by Region
4.3 Global Offlabel Drugs Market by Region
Chapter 5. Global Huntington's Disease Treatment Market by Distribution Channel
5.1 Global Hospital Pharmacies Market by Region
5.2 Global Drug Store & Retail Pharmacies Market by Region
5.3 Global Online Pharmacies Market by Region
Chapter 6. Global Huntington's Disease Treatment Market by Age
6.1 Global Below 50 years Market by Region
6.2 Global Above 50 years Market by Region
Chapter 7. Global Huntington's Disease Treatment Market by Region
7.1 North America Huntington's Disease Treatment Market
7.1.1 North America Huntington's Disease Treatment Market by Drug Type
7.1.1.1 North America Approved Drugs Market by Region
7.1.1.2 North America Huntington's Disease Treatment Market by Approved Drugs Type
7.1.1.2.1 North America Tetrabenazine Market by Country
7.1.1.2.2 North America Deutetrabenazine Market by Country
7.1.1.3 North America Offlabel Drugs Market by Region
7.1.2 North America Huntington's Disease Treatment Market by Distribution Channel
7.1.2.1 North America Hospital Pharmacies Market by Country
7.1.2.2 North America Drug Store & Retail Pharmacies Market by Country
7.1.2.3 North America Online Pharmacies Market by Country
7.1.3 North America Huntington's Disease Treatment Market by Age
7.1.3.1 North America Below 50 years Market by Country
7.1.3.2 North America Above 50 years Market by Country
7.1.4 North America Huntington's Disease Treatment Market by Country
7.1.4.1 US Huntington's Disease Treatment Market
7.1.4.1.1 US Huntington's Disease Treatment Market by Drug Type
7.1.4.1.1.1 US Huntington's Disease Treatment Market by Approved Drugs Type
7.1.4.1.2 US Huntington's Disease Treatment Market by Distribution Channel
7.1.4.1.3 US Huntington's Disease Treatment Market by Age