세계 프리팩 크로마토그래피 칼럼 시장 규모는 2024년 22억 달러에 달했습니다. 향후 IMARC 그룹은 2033년까지 시장 규모가 39억 달러에 달할 것으로 예상하며, 2025-2033년 연평균 성장률(CAGR)은 6.3%를 보일 것으로 예측했습니다. 다양한 만성질환의 유병률 증가, 질병 관리를 위한 바이오의약품에 대한 수요 증가, 다양한 산업 분야에서 크로마토그래피의 사용 확대 등이 시장 성장을 이끄는 주요 요인 중 하나입니다.
바이오의약품에 대한 수요 증가
암, 당뇨병, 심혈관질환, 자가면역질환 등 다양한 만성질환의 유병률 증가가 시장 성장을 가속하고 있습니다. 이는 질병 관리를 위한 바이오의약품에 대한 수요 증가와 함께 시장 성장을 강화하고 있습니다. NIH에 따르면 2022년 인도에서 암으로 인한 사망자 수는 14,61,427명(조사율 100.4/100,000)으로 추산됩니다. 소아(0-14세) 암 중 림프성 백혈병(남아 29.2%, 여아 24.2%)이 주요 부위였습니다. 암 발병률은 2020년 대비 2025년에는 12.8% 증가할 것으로 추정됩니다. 예를 들어 IDF 당뇨병 아틀라스(2021)에 따르면 성인 인구(20-79세)의 10.5%가 당뇨병을 앓고 있으며, 절반 가까이가 자신이 당뇨병을 앓고 있다는 사실을 모르고 있습니다. IDF의 예측에 따르면 2045년까지 성인 8명 중 1명, 약 7억 8,300만 명이 당뇨병을 앓게 될 것이며, 그 비율은 46% 증가할 것으로 예측됩니다. 이는 프리팩 크로마토그래피 칼럼 시장 통계에 큰 영향을 미칩니다.
크로마토그래피의 눈부신 기술 발전
크로마토그래피 기술의 지속적인 발전도 시장을 주도하고 있습니다. 예를 들어 고속 액체 크로마토그래피(HPLC) 및 친 화성 크로마토그래피를 포함한 크로마토그래피 기술의 지속적인 기술 혁신으로 분리 효율, 속도 및 분리 능력이 향상되고 있습니다. 환경 검사에서 크로마토그래피의 보급은 시장 성장에 영향을 미치고 있습니다. 예를 들어2023년 6월,Agilent Technologies Inc.는 두 가지 새로운 액체 크로마토그래프 질량분석 시스템(LCMS)인 Agilent 6495D LC/TQ와 Agilent Revident LC/Q-TQF를 발표했습니다. Agilent는 Revident LC/Q-TQF의 하이엔드 성능을 촉진하기 위해 새로운 Agilent MassHunter Explorer 프로파일링 소프트웨어와 새로운 Agilent ChemVistra 라이브러리 관리자 소프트웨어도 발표했습니다. 이는 향후 수년간 프리팩 크로마토그래피 칼럼 시장 예측에 탄력을 받을 것으로 예측됩니다.
바이오프로세스 및 일회용 기술에 대한 관심 증가
바이오 제약 및 생명공학 산업에서는 생산 효율화와 교차 오염 위험을 줄이기 위해 일회용 기술에 대한 관심이 높아지고 있으며, 이는 시장 성장에 기여하고 있습니다. 일회용 프리패킹 컬럼은 배치 간 세척 및 검증 과정을 생략하여 귀중한 생산 시간 활용을 최적화하고, 보다 효율적이고 비용 효율적인 제조를 가능하게 합니다. 예를 들어 2023년 9월, 바이오프로세스 기술 리더십에 초점을 맞춘 생명과학 기업 Repligen Corporation은 스웨덴 Molndal의 비상장 기업 Metenova AB(Metenova)를 인수하는 정식 계약을 체결했다고 발표했습니다. (Metenova). Metenova는 전 세계 바이오제약 기업 및 개발 및 제조수탁기관(CDMO)에서 널리 사용되고 있는 마그네틱 믹싱 기술 및 드라이브트레인 기술의 성공에 힘입어 2023년 2,400만-2,500만 달러의 매출을 예상하고 있습니다. 이 회사는 최근 기존 스테인리스강(반복 사용) 제품 라인의 성공을 바탕으로 MixOne 플랫폼을 출시하여 일회용 믹싱 시장에 진출했습니다.
The global prepacked chromatography columns market size reached USD 2.2 Billion in 2024. Looking forward, IMARC Group expects the market to reach USD 3.9 Billion by 2033, exhibiting a growth rate (CAGR) of 6.3% during 2025-2033. The growing prevalence of various chronic diseases, the rising demand for biopharmaceuticals for disease management, and increasing utilization of chromatography across various industries are some of the major factors propelling the growth of the market.
Increased Demand for Biopharmaceuticals
The rising prevalence of various chronic diseases including cancer, diabetes, cardiovascular disorders, and autoimmune conditions is driving the growth of the market. This, coupled with the escalating demand for biopharmaceuticals for disease management is strengthening the growth of the market. According to NIH, the estimated number of incident cases of cancer in India for the year 2022 was found to be 14,61,427 (crude rate:100.4 per 100000). Among the childhood (0-14 yr) cancers, lymphoid leukemia (boys: 29.2% and girls: 24.2%) was the leading site. The incidence of cancer cases is estimated to increase by 12.8% in 2025 as compared to 2020. For instance, IDF Diabetes Atlas (2021) reports that 10.5% of the adult population (20-79 years) has diabetes, with almost half unaware that they are living with the condition. By 2045, IDF projections show that one in eight adults approximately 783 million, will be living with diabetes an increase of 46%. This is infleuncing the prepacked chromatography columns market statistics significantly.
Significant Technological Advancement in Chromatography
The market is also driven by continuous advancements in chromatography technology. For instance, ongoing innovations in chromatographic techniques including high-performance liquid chromatography (HPLC) and affinity chromatography are improving the efficiency, speed, and resolution of separation. The widespread adoption of chromatography in environmental testing is influencing the growth of the market. For instance, in June 2023, Agilent Technologies Inc. announced two new liquid chromatography-mass spectrometry systems (LCMS), the Agilent 6495D LC/TQ and the Agilent Revident LC/Q-TQF. Facilitating the high-end performance of the Revident LC/Q-TQF, Agilent is also announcing the new Agilent MassHunter Explorer Profiling software and the new Agilent ChemVistra library manager software. This is expected to fuel the prepacked chromatography columns market forecast over the coming years.
Rising Emphasis on Bioprocessing and Single-Use Technologies
The increasing focus of biopharmaceutical and biotechnology industries towards single-use technologies to streamline production and reduce cross-contamination risk is contributing to the growth of the market. Single-use prepackaged columns optimize the use of valuable production time by eliminating the need for cleaning and validation steps between batches which leads to more efficient and cost-effective manufacturing. For instance, in September 2023, Repligen Corporation, a life sciences company focused on bioprocessing technology leadership, announced that it has entered into a definitive agreement to acquire privately held Metenova AB (Metenova) of Molndal, Sweden. Metenova is projected to generate revenues of $24 million to $25 million for fiscal year 2023, led by the success of its magnetic mixing and drive train technologies that are widely used by global biopharmaceutical companies and contract development and manufacturing organizations (CDMOs). The company recently entered the single-use mixing market with the launch of its MixOne platform, leveraging the success of its existing stainless steel (repeat-use) product line.
>1000 ML accounts for the majority of the market share
The rising preference for large column sizes across different industry verticals is driving the market segment. >1000 ML prepacked columns are commonly employed for the purification of biomolecules such as monoclonal antibodies, proteins, and vaccines. They facilitate high-capacity chromatographic separations, ensuring the production of pure and high-quality biopharmaceutical products. Additionally, food and beverage (F&B) manufacturers utilize >1000 mL prepacked columns for tasks like flavor extraction, quality control, and the separation of components like sugars, amino acids, and colorants. These columns aid in achieving consistent product quality and compliance with food safety regulations. In chemical research and development (R&D), these columns are essential for synthesizing and purifying compounds. Researchers can scale up their chromatographic processes efficiently, saving time and resources while ensuring product purity.
Ion-exchange chromatography holds the majority of the market share
Ion-exchange chromatography is versatile and can be applied to a wide range of biomolecules, including proteins, nucleic acids, and other charged molecules. This adaptability makes it suitable for various research and industrial applications. Additionally, it offers excellent selectivity based on the charge of the molecules being separated. By using ion-exchange resins with different functional groups, researchers can effectively separate and purify target molecules from complex mixtures. Apart from this, it provides high-resolution separation, enabling the isolation of closely related species with different charge properties. Furthermore, it can be easily scaled up for industrial production, making it suitable for large-scale purification processes in biopharmaceuticals, food processing, and other industries.
Sample preparation represents the largest market segment
Sample preparation is a fundamental prerequisite for chromatographic analyses which is fueling the segment growth in the market. It involves the extraction, clean-up, and concentration of target molecules from complex samples, ensuring that only relevant compounds reach the chromatography columns. The quality of sample preparation directly influences the accuracy and sensitivity of subsequent chromatographic analyses, making it an essential step. Additionally, diverse industries, including pharmaceuticals, biotechnology, food and beverage, environmental monitoring, and healthcare, heavily rely on chromatography for quality control, research, and product development. Furthermore, ongoing advancements in analytical techniques, such as high-performance liquid chromatography (HPLC) and mass spectrometry (MS), demand sample preparation methods that can cater to evolving needs.
Pharmaceutical and biotechnology companies account for the largest market share
Pharmaceutical and biotechnology companies are subject to rigorous regulatory requirements to ensure the safety and efficacy of their products which is further driving the segment growth in the market. Chromatography is a trusted and standardized method for characterizing and purifying compounds, making prepacked columns an attractive option for achieving compliance and maintaining consistency in manufacturing. Moreover, the continuous advancements in biopharmaceuticals, including monoclonal antibodies and gene therapies, have led to increased demand for specialized chromatography columns tailored to these complex molecules. Furthermore, these industries rely on precise and efficient separation and purification of biomolecules, such as proteins, antibodies, and nucleic acids, at various stages of drug development, production, and quality control. Prepacked chromatography columns offer ready-to-use solutions that significantly streamline these processes, reducing time and labor costs.
North America leads the market, accounting for the largest prepacked chromatography columns market share
The report has also provided a comprehensive analysis of all the major regional markets, which include North America (the United States and Canada); Europe (Germany, France, the United Kingdom, Italy, Spain, Russia, and others); Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others); Latin America (Brazil, Mexico, and others); and the Middle East and Africa. According to the report, North America represents the largest regional market for prepacked chromatography columns.
North America is home to numerous pharmaceutical and biotechnology companies engaged in drug discovery, development, and production which is driving the market growth. Additionally, pharmaceutical and biotechnology sectors in North America are subject to strict regulatory standards set by the U.S. Food and Drug Administration (FDA) and Health Canada. Apart from this, several major players in the chromatography column manufacturing industry are headquartered or have a significant presence in North America. This concentration of key industry players fosters competition, innovation, and a wide range of product offerings. Furthermore, the region boasts advanced healthcare infrastructure, including cutting-edge diagnostic laboratories and healthcare facilities. Chromatography is extensively used in clinical diagnostics and research, further fueling the demand for prepacked columns. For instance, in February 2024, Shimadzu Corporation acquired the catalytic micro-reactive business for gas chromatography (GC) from Activated Research Company, LLC (ARC, Minnesota, USA).
(Please note that this is only a partial list of the key players, and the complete list is provided in the report.)