U.S. DNA Synthesis Market Size, Share & Trends Analysis Report By Service Type (Gene Synthesis, Oligonucleotide Synthesis), By Application (Research Development, Diagnostics), By End Use, And Segment Forecasts, 2025 - 2033
The U.S. DNA synthesis market size was estimated at USD 1.25 billion in 2024 and is projected to reach USD 4.62 billion by 2033, expanding at a CAGR of 15.93% from 2025 to 2033. This high growth is driven by increasing demand in synthetic biology, personalized medicine, and biotechnology research. Advancements in gene editing technologies and declining costs of U.S. DNA synthesis are further accelerating market expansion. The U.S. remains a key player in global genomic innovation, supported by strong investment in R&D and a well-established biotech infrastructure.
U.S. DNA Synthesis Market Report Segmentation
This report forecasts revenue growth and provides an analysis on the latest trends in each of the sub-segments from 2021 to 2033. For the purpose of this report, Grand View Research has segmented the U.S. DNA synthesis market on the basis of service type, application, and end use.
Service Type Outlook (Revenue, USD Million, 2021 - 2033)
Oligonucleotide Synthesis
By Type
Standard Oligonucleotide Synthesis
Custom Oligonucleotide Synthesis
By Length
Less than 50 nt
51-100 nt
101-150 nt
More than 150 nt
Gene Synthesis
By Type
Custom Gene Synthesis
Gene Library Synthesis
By Length
Less than 500 nt
501-1000 nt
1001-1500 nt
1501-2000 nt
2001-2500 nt
More than 2500 nt
Application Outlook (Revenue, USD Million, 2021 - 2033)
Research and Development
Oligonucleotide Synthesis
PCR
NGS
CRISPR
Cloning and Mutagenesis
Others
Gene Synthesis
Synthetic Biology
Vaccine Development
Genetic Engineering
Others
Diagnostics
Therapeutics
RNAi Therapies
Antisense Oligonucleotide-based Therapies
Others
End Use Outlook (Revenue, USD Million, 2021 - 2033)
Biopharmaceutical and Diagnostics Companies
Academic and Research Institutes
Contract Research Organizations
Table of Contents
Chapter 1. Methodology and Scope
1.1. Market Segmentation & Scope
1.2. Segment Definitions
1.2.1. Service Type
1.2.2. Application
1.2.3. End Use
1.3. Research Methodology
1.4. Information Procurement
1.4.1. Purchased database
1.4.2. GVR's internal database
1.4.3. Secondary sources
1.4.4. Primary research
1.5. Information or Data Analysis
1.5.1. Data analysis models
1.6. Market Formulation & Validation
1.7. Model Details
1.8. List of Secondary Sources
1.9. List of Primary Sources
1.10. Objectives
Chapter 2. Executive Summary
2.1. Market Outlook
2.2. Segment Snapshot
2.3. Competitive Insights Landscape
Chapter 3. U.S. DNA Synthesis Market Variables, Trends & Scope
3.1. Market Lineage Outlook
3.1.1. Parent market outlook
3.1.2. Related/ancillary market outlook.
3.2. Market Dynamics
3.2.1. Market driver analysis
3.2.2. Market restraint analysis
3.3. U.S. DNA synthesis Market Analysis Tools
3.3.1. Industry Analysis - Porter's
3.3.2. PESTEL Analysis
Chapter 4. U.S. DNA Synthesis Market: Service Type Estimates & Trend Analysis
4.1. Segment Dashboard
4.2. U.S. DNA Synthesis Market Service Type Movement Analysis
4.3. U.S. DNA Synthesis Market Size & Trend Analysis, by Service Type, 2021 to 2033 (USD Million)
4.4. Oligonucleotide synthesis
4.4.1. Oligonucleotides synthesis market estimates and forecasts 2021 to 2033 (USD Million)
4.4.2. By Type
4.4.2.1. Standard oligonucleotides synthesis
4.4.2.1.1. Standard oligonucleotides synthesis market estimates and forecasts 2021 to 2033 (USD Million)
4.4.2.2. Custom oligonucleotide synthesis
4.4.2.2.1. Custom oligonucleotides synthesis market estimates and forecasts 2021 to 2033 (USD Million)
4.4.3. By Length
4.4.3.1. Less than 50nt
4.4.3.1.1. Less than 50nt market estimates and forecasts 2021 to 2033 (USD Million)
4.4.3.2. 51-100nt
4.4.3.2.1. 51-100nt market estimates and forecasts 2021 to 2033 (USD Million)
4.4.3.3. 101-150nt
4.4.3.3.1. 101-150nt synthesis market estimates and forecasts 2021 to 2033 (USD Million)
4.4.3.4. More than 150nt
4.4.3.4.1. More than 150nt synthesis market estimates and forecasts 2021 to 2033 (USD Million)
4.5. Gene synthesis
4.5.1. Gene synthesis market estimates and forecasts 2021 to 2033 (USD Million)
4.5.2. By Type
4.5.2.1. Custom gene synthesis
4.5.2.1.1. Custom gene synthesis market estimates and forecasts 2021 to 2033 (USD Million)
4.5.2.2. Gene library synthesis
4.5.2.2.1. Gene library synthesis market estimates and forecasts 2021 to 2033 (USD Million)
4.5.3. By Length
4.5.3.1. Less than 500nt
4.5.3.1.1. Less than 500nt market estimates and forecasts 2021 to 2033 (USD Million)
4.5.3.2. 501-1000nt
4.5.3.2.1. 501-1000nt market estimates and forecasts 2021 to 2033 (USD Million)
4.5.3.3. 1001-1500nt
4.5.3.3.1. 1001-1500nt synthesis market estimates and forecasts 2021 to 2033 (USD Million)
4.5.3.4. 1501-2000nt
4.5.3.4.1. 1501-2000nt synthesis market estimates and forecasts 2021 to 2033 (USD Million)
4.5.3.5. 2001-2500nt
4.5.3.5.1. 2001-2500nt synthesis market estimates and forecasts 2021 to 2033 (USD Million)
4.5.3.6. More than 2500nt
4.5.3.6.1. More than 2500nt synthesis market estimates and forecasts 2021 to 2033 (USD Million)
Chapter 5. U.S. DNA Synthesis Market: Application Estimates & Trend Analysis
5.1. Segment Dashboard
5.2. U.S. DNA Synthesis Market Application Movement Analysis
5.3. U.S. DNA Synthesis Market Size & Trend Analysis, by Application, 2021 to 2033 (USD Million)
5.4. Research & Development
5.4.1. Research & development market estimates and forecasts 2021 to 2033 (USD Million)
5.4.2. Oligonucleotide synthesis
5.4.2.1. Oligonucleotide synthesis tumors market estimates and forecasts 2021 to 2033 (USD Million)
5.4.2.2. PCR
5.4.2.2.1. PCR synthesis tumors market estimates and forecasts 2021 to 2033 (USD Million)
5.4.2.3. NGS
5.4.2.3.1. NGS synthesis tumors market estimates and forecasts 2021 to 2033 (USD Million)
5.4.2.4. CRISPR
5.4.2.4.1. CRISPR synthesis tumors market estimates and forecasts 2021 to 2033 (USD Million)
5.4.2.5. Cloning and mutagenesis
5.4.2.5.1. Cloning and mutagenesis synthesis tumors market estimates and forecasts 2021 to 2033 (USD Million)
5.4.2.6. Others
5.4.2.6.1. Others synthesis tumors market estimates and forecasts 2021 to 2033 (USD Million)
5.4.3. Gene synthesis
5.4.3.1. Gene synthesis market estimates and forecasts 2021 to 2033 (USD Million)
5.4.3.2. Synthetic biology
5.4.3.2.1. Synthetic biology tumors market estimates and forecasts 2021 to 2033 (USD Million)
5.4.3.3. Vaccine development
5.4.3.3.1. Vaccine development synthesis tumors market estimates and forecasts 2021 to 2033 (USD Million)
5.4.3.4. Genetic engineering
5.4.3.4.1. Genetic engineering synthesis tumors market estimates and forecasts 2021 to 2033 (USD Million)
5.4.3.5. Others
5.4.3.5.1. Others synthesis tumors market estimates and forecasts 2021 to 2033 (USD Million)
5.5. Diagnostics
5.5.1. Diagnostics market estimates and forecasts 2021 to 2033 (USD Million)
5.6. Therapeutics
5.6.1. Therapeutics market estimates and forecasts 2021 to 2033 (USD Million)
5.6.2. RNAi therapies
5.6.2.1. RNAi therapies market estimates and forecasts 2021 to 2033 (USD Million)
5.6.3. Antisense and oligonucleotide-based therapies
5.6.3.1. Antisense and oligonucleotide-based therapies market estimates and forecasts 2021 to 2033 (USD Million)
5.6.4. Others
5.6.4.1. Others market estimates and forecasts 2021 to 2033 (USD Million)
Chapter 6. U.S. DNA Synthesis Market: End Use Estimates & Trend Analysis
6.1. Segment Dashboard
6.2. U.S. DNA Synthesis Market End Use Movement Analysis
6.3. U.S. DNA Synthesis Market Size & Trend Analysis, by End Use, 2021 to 2033 (USD Million)
6.4. Biopharmaceutical & Diagnostic Companies
6.4.1. Biopharmaceutical & diagnostic companies market estimates and forecasts 2021 to 2033 (USD Million)
6.5. Academic & Research Institutes
6.5.1. Academic & research institutes market estimates and forecasts 2021 to 2033 (USD Million)
6.6. Contract Research Organizations
6.6.1. Contract Research Organizations market estimates and forecasts 2021 to 2033 (USD Million)