항혈관내피세포성장인자 치료 시장 규모, 점유율, 동향 분석 보고서 : 제품별, 질환별, 지역별, 부문별 예측(2025-2030년)

Anti-vascular Endothelial Growth Factor Therapeutics Market Size, Share & Trends Analysis Report By Product (Eylea, Lucentis, Beovu), By Disease (Macular Edema, Diabetic Retinopathy, Retinal Vein Occlusion), By Region, And Segment Forecasts, 2025 - 2030

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한글목차

항혈관내피세포성장인자 치료 시장 성장 및 동향

Grand View Research, Inc.의 최신 보고서에 따르면, 세계 항혈관내피세포성장인자 치료 시장 규모는 2030년까지 129억 달러에 달할 것으로 예상되며, 예측 기간 동안 연평균 -2.35%의 CAGR을 기록할 것으로 예상됩니다. 신약 개발을 촉진하기 위한 항 VEGF 치료제 연구개발에 대한 자금 지원 증가는 시장 성장을 가속화할 것으로 예상됩니다. 또한, 안과 질환에 취약한 노인 인구의 증가와 함께 새로운 혁신 제품의 채택은 예측 기간 동안 시장 성장을 촉진할 것으로 예상됩니다.

유엔 경제사회국의 데이터에 따르면 2019년 전 세계 고령자(60세 이상)는 약 7억 3천만 명으로 65세 이상 인구 비율은 6%였으며, 2019년에는 9%로 증가했습니다. 고령화 인구를 국가별로 보면 2017년 아프리카 약 6,870만 명, 아시아 약 5억 4,920만 명, 유럽 약 1억 8,300만 명, 북미 약 7,840만 명, 라틴아메리카 및 기타 중동 및 아프리카 약 7,600만 명 이상이었습니다. 따라서 노인 인구의 증가가 시장을 견인할 것으로 예상됩니다.

개발도상국의 경우, 재정보전금 제도가 없기 때문에 비용 효율적인 새로운 분자에 대한 요구가 증가하고 있습니다. 또한, 안과 의사들이 보다 효과적인 신약으로 전환함에 따라 기업들은 산업적 지위를 유지하기 위해 연구개발에 투자할 수밖에 없는 상황입니다. 기존 약물의 바이오시밀러에 대한 연구자들의 관심은 항VEGF 치료 파이프라인의 주요 트렌드입니다.

또한, 각 업체들은 이러한 치료제의 채택을 증가시킬 수 있는 다양한 제형과 약물전달 시스템을 개발하고 있습니다. 예를 들어, F. Hoffmann-La Roche Ltd.는 포트 전달 시스템-RG6321(라니비주맙)을 개발하고 있으며, 현재 임상 3상 시험을 진행 중입니다. 이 시스템은 리필 가능한 안구 임플란트로, 맞춤형 제형의 라니비주맙을 수개월에 걸쳐 지속적으로 투여할 수 있습니다.

특허 보호의 상실은 시장 성장에 부정적인 영향을 미칠 가능성이 높으며, 주요 기업들은 새로운 수익원을 모색하고 있습니다. 그러나 그 결과, 바이오시밀러 의약품 생산업체들이 새로운 시장을 형성하고 있습니다. 이러한 경쟁의 심화는 시장 성장을 저해하는 요인으로 작용할 것으로 예상됩니다. 그러나 경쟁 우위를 가진 신제품의 출시로 인해 예측 기간 동안 이러한 경쟁의 영향은 감소할 것으로 예상됩니다.

항혈관내피세포성장인자 치료 시장 보고서 하이라이트

• 2024년에는 연령 관련 황반변성(AMD)이 가장 큰 매출 점유율을 차지했으며, 예측 기간 동안에도 그 우위를 유지할 것으로 예상됩니다.
• 2024년 제품별 시장 점유율은 Eylea가 61.9%로 가장 큰 비중을 차지했으며, Eylea(aflibercept)는 Regeneron Pharmaceuticals가 Bayer와 공동 개발한 항VEGF 치료제로 습성 노인성 황반변성(AMD), 당뇨병성 황반부종(DME), 망막정맥폐쇄증(RVO) 등의 망막질환 치료제로 각광받고 있습니다.
• 북미 항혈관내피세포성장인자 치료 시장은 2024년 매출 점유율 65.71%를 차지하며 전 세계 시장을 주도했습니다. 이는 연령 관련 황반변성(AMD), 당뇨망막병증, 망막정맥폐쇄증, 황반부종 등 안과 관련 질환의 유병률 증가에 기인합니다.

목차

제1장 조사 방법과 범위

제2장 주요 요약

제3장 항혈관내피세포성장인자 치료 시장 변수, 동향, 범위

• 시장 계통 전망
  • 상부 시장 전망
  • 관련/부수 시장 전망
• 시장 역학
  • 시장 성장 촉진요인 분석
  • 시장 성장 억제요인 분석
• 항혈관내피세포성장인자 치료 시장 분석 툴
  • 산업 분석 - Porter's Five Forces 분석
  • PESTEL 분석

제4장 항혈관내피세포성장인자 치료 시장 : 제품별, 추정·동향 분석

• 부문 대시보드
• 항혈관내피세포성장인자 치료 시장 : 제품 변동 분석
• 항혈관내피세포성장인자 치료 시장 : 제품별 전망
• 2018-2030년 시장 규모와 예측과 동향 분석
• Eylea
• Lucentis
• Beovu
• Vabysmo
• 기타

제5장 항혈관내피세포성장인자 치료 시장 : 질환별, 추정·동향 분석

• 부문 대시보드
• 항혈관내피세포성장인자 치료 시장 : 질환 변동 분석
• 항혈관내피세포성장인자 치료 시장 : 질환별 전망
• 2018-2030년 시장 규모와 예측과 동향 분석
• 황반부종
• 당뇨망막병증
• 망막정맥폐쇄증
• 노인황반변성
• 근시성 맥락막 신생 혈관

제6장 항혈관내피세포성장인자 치료 시장 : 지역별, 추정·동향 분석

• 지역 대시보드
• 시장 규모, 예측 동향 분석, 2018-2030년
• 북미
  • 미국
  • 캐나다
  • 멕시코
• 유럽
  • 영국
  • 독일
  • 프랑스
  • 이탈리아
  • 스페인
  • 노르웨이
  • 스웨덴
  • 덴마크
• 아시아태평양
  • 일본
  • 중국
  • 인도
  • 호주
  • 한국
  • 태국
• 라틴아메리카
  • 브라질
  • 아르헨티나
• 중동 및 아프리카
  • 남아프리카공화국
  • 사우디아라비아
  • 아랍에미리트
  • 쿠웨이트

제7장 경쟁 구도

• 기업 분류
• 주요 시장 진출 기업의 최근 동향과 영향 분석
• 기업 시장 점유율 분석, 2024년
• 기업 개요
  • Regeneron Pharmaceuticals, Inc.
  • Bayer AG
  • Novartis AG
  • F. Hoffmann-La Roche Ltd.
  • Biogen
  • Pfizer, Inc.
  • Coherus BioSciences, Inc.
  • Amgen, Inc.
  • Bausch Health Companies, Inc.
  • Viatris, Inc.

ksm

영문 목차

영문목차

Anti-Vascular Endothelial Growth Factor Therapeutics Market Growth & Trends:

The global anti-vascular endothelial growth factor therapeutics market size is expected to reach USD 12.90 billion by 2030, registering a CAGR of -2.35% over the forecast period, according to a new report by Grand View Research, Inc. Increased funding for R&D of anti-VEGF therapeutics to boost the development of new drugs is expected to accelerate market growth. Moreover, the introduction of novel innovative products coupled with the increasing geriatric population that is susceptible to develop ophthalmic diseases is expected to propel the market growth over the forecast period.

According to the United Nations Department of Economic and Social Affairs data, the global elderly population (aged 60 years and above) was around 703 million in 2019. The share of the population aged 65 years and above was 6%, which increased to 9% in 2019. The aging population, based on countries, was around 68.7 million in Africa, 549.2 million in Asia, 183 million in Europe, 78.4 million in North America, and more than 76 million in Latin America & other regions in 2017. Hence, the increasing geriatric population is anticipated to drive the market.

The lack of reimbursement policies in developing regions is creating an opportunity for cost-effective novel molecules. In addition, ophthalmologists switching to more effective newly launched drugs has compelled companies to invest in R&D to maintain their industry position. The interest of investigators on biosimilar of existing drugs is a major trend in the pipeline of anti-VEGF therapeutics.

Moreover, companies are developing various formulations and drug delivery systems that may increase the adoption of these therapies. For instance, F. Hoffmann La Roche Ltd. is developing the port delivery system-RG6321 (Ranibizumab)-which is currently undergoing a phase III clinical trial. It is an eye implant that is refillable and continuously delivers a customized formulation of ranibizumab over a period of months.

Loss of patent protection is likely to have a negative impact on the market growth and has led big pharma companies to consider new revenue streams. However, this is creating an emerging market for biosimilar drug producers in the space. This rising competition is anticipated to impede market growth. However, the launch of novel products with a competitive advantage is anticipated to lower the impact of the restraint during the forecast period.

Anti-vascular Endothelial Growth Factor Therapeutics Market Report Highlights:

• In 2024, Age-related Macular Degeneration (AMD) accounted for the largest revenue share and is anticipated to maintain its dominance over the forecast period
• Eylea dominated the product segment with the largest market share of 61.9% in 2024. Eylea (aflibercept), developed by Regeneron Pharmaceuticals in collaboration with Bayer, has been a foremost anti-VEGF therapy for treating retinal diseases such as wet age-related macular degeneration (AMD), diabetic macular edema (DME), and retinal vein occlusion (RVO
• North America anti-vascular endothelial growth factor therapeutics market dominated the global industry and accounted for 65.71% of revenue share in 2024, which can be attributed to the increasing prevalence of eye-related conditions such as age-related macular degeneration (AMD), diabetic retinopathy, retinal vein occlusion, and macular edema

Table of Contents

Chapter 1. Methodology and Scope

• 1.1. Market Segmentation and Scope
• 1.2. Segment Definitions
  • 1.2.1. Product
  • 1.2.2. Disease
  • 1.2.3. Regional Scope
  • 1.2.4. Estimates and forecasts timeline
• 1.3. Research Methodology
• 1.4. Information Procurement
  • 1.4.1. Purchased database
  • 1.4.2. GVR's internal database
  • 1.4.3. Secondary sources
  • 1.4.4. Primary research
  • 1.4.5. Details of primary research
• 1.5. Information or Data Analysis
  • 1.5.1. Data analysis models
• 1.6. Market Formulation & Validation
• 1.7. Model Details
  • 1.7.1. Commodity flow analysis (Model 1)
  • 1.7.2. Approach 1: Commodity flow approach
  • 1.7.3. Volume price analysis (Model 2)
  • 1.7.4. Approach 2: Volume price analysis
• 1.8. List of Secondary Sources
• 1.9. List of Primary Sources
• 1.10. Objectives

Chapter 2. Executive Summary

• 2.1. Market Outlook
• 2.2. Segment Outlook
  • 2.2.1. Product outlook
  • 2.2.2. Disease outlook
• 2.3. Regional outlook
• 2.4. Competitive Insights

Chapter 3. Anti-Vascular Endothelial Growth Factor Therapeutics Market Variables, Trends & Scope

• 3.1. Market Lineage Outlook
  • 3.1.1. Parent Market Outlook
  • 3.1.2. Related/ancillary market outlook
• 3.2. Market Dynamics
  • 3.2.1. Market Driver Analysis
    • 3.2.1.1. Increasing prevalence of target diseases
    • 3.2.1.2. Advancements in drug delivery and development
    • 3.2.1.3. Rising awareness about early diagnosis and treatment of ocular disorders
  • 3.2.2. Market Restraint Analysis
    • 3.2.2.1. High cost of anti-VEGF therapeutics
    • 3.2.2.2. Potential side effects and safety concerns
• 3.3. Anti-Vascular Endothelial Growth Factor Therapeutics Market Analysis Tools
  • 3.3.1. Industry Analysis - Porter's
    • 3.3.1.1. Bargaining power of suppliers
    • 3.3.1.2. Bargaining power of buyers
    • 3.3.1.3. Threat of substitutes
    • 3.3.1.4. Threat of new entrants
    • 3.3.1.5. Competitive rivalry
  • 3.3.2. PESTEL Analysis
    • 3.3.2.1. Political landscape
    • 3.3.2.2. Economic landscape
    • 3.3.2.3. Social landscape
    • 3.3.2.4. Technological landscape
    • 3.3.2.5. Environmental landscape
    • 3.3.2.6. Legal landscape

Chapter 4. Anti-Vascular Endothelial Growth Factor Therapeutics Market: Product Estimates & Trend Analysis

• 4.1. Segment Dashboard
• 4.2. Anti-Vascular Endothelial Growth Factor Therapeutics Market: Product Movement Analysis
• 4.3. Anti-Vascular Endothelial Growth Factor Therapeutics Market by Product Outlook (USD Million)
• 4.4. Market Size & Forecasts and Trend Analyses, 2018 to 2030 for the following
• 4.5. Eylea
  • 4.5.1. Market Estimates And Forecast, 2018 - 2030 (USD Million)
• 4.6. Lucentis
  • 4.6.1. Market Estimates And Forecast, 2018 - 2030 (USD Million)
• 4.7. Beovu
  • 4.7.1. Market Estimates And Forecast, 2018 - 2030 (USD Million)
• 4.8. Vabysmo
  • 4.8.1. Market Estimates And Forecast, 2018 - 2030 (USD Million)
• 4.9. Others
  • 4.9.1. Market Estimates And Forecast, 2018 - 2030 (USD Million)

Chapter 5. Anti-Vascular Endothelial Growth Factor Therapeutics Market: Disease Estimates & Trend Analysis

• 5.1. Segment Dashboard
• 5.2. Anti-Vascular Endothelial Growth Factor Therapeutics Market: Disease Movement Analysis
• 5.3. Anti-Vascular Endothelial Growth Factor Therapeutics Market by Disease Outlook (USD Million)
• 5.4. Market Size & Forecasts and Trend Analyses, 2018 to 2030 for the following
• 5.5. Macular Edema
  • 5.5.1. Market Estimates And Forecast, 2018 - 2030 (USD Million)
• 5.6. Diabetic Retinopathy
  • 5.6.1. Market Estimates And Forecast, 2018 - 2030 (USD Million)
• 5.7. Retinal Vein Occlusion
  • 5.7.1. Market Estimates And Forecast, 2018 - 2030 (USD Million)
• 5.8. Age-related Macular Degeneration
  • 5.8.1. Market Estimates And Forecast, 2018 - 2030 (USD Million)
• 5.9. Myopic Choroidal Neovascularization
  • 5.9.1. Market Estimates And Forecast, 2018 - 2030 (USD Million)

Chapter 6. Anti-Vascular Endothelial Growth Factor Therapeutics Market: Regional Estimates & Trend Analysis

• 6.1. Regional Dashboard
• 6.2. Market Size, & Forecasts Trend Analysis, 2018 to 2030:
• 6.3. North America
  • 6.3.1. U.S.
    • 6.3.1.1. Key country dynamics
    • 6.3.1.2. Regulatory framework/ reimbursement structure
    • 6.3.1.3. Competitive scenario
    • 6.3.1.4. U.S. market estimates and forecasts 2018 to 2030 (USD Million)
  • 6.3.2. Canada
    • 6.3.2.1. Key country dynamics
    • 6.3.2.2. Regulatory framework/ reimbursement structure
    • 6.3.2.3. Competitive scenario
    • 6.3.2.4. Canada market estimates and forecasts 2018 to 2030 (USD Million)
  • 6.3.3. Mexico
    • 6.3.3.1. Key country dynamics
    • 6.3.3.2. Regulatory framework/ reimbursement structure
    • 6.3.3.3. Competitive scenario
    • 6.3.3.4. Mexico market estimates and forecasts 2018 to 2030 (USD Million)
• 6.4. Europe
  • 6.4.1. UK
    • 6.4.1.1. Key country dynamics
    • 6.4.1.2. Regulatory framework/ reimbursement structure
    • 6.4.1.3. Competitive scenario
    • 6.4.1.4. UK market estimates and forecasts 2018 to 2030 (USD Million)
  • 6.4.2. Germany
    • 6.4.2.1. Key country dynamics
    • 6.4.2.2. Regulatory framework/ reimbursement structure
    • 6.4.2.3. Competitive scenario
    • 6.4.2.4. Germany market estimates and forecasts 2018 to 2030 (USD Million)
  • 6.4.3. France
    • 6.4.3.1. Key country dynamics
    • 6.4.3.2. Regulatory framework/ reimbursement structure
    • 6.4.3.3. Competitive scenario
    • 6.4.3.4. France market estimates and forecasts 2018 to 2030 (USD Million)
  • 6.4.4. Italy
    • 6.4.4.1. Key country dynamics
    • 6.4.4.2. Regulatory framework/ reimbursement structure
    • 6.4.4.3. Competitive scenario
    • 6.4.4.4. Italy market estimates and forecasts 2018 to 2030 (USD Million)
  • 6.4.5. Spain
    • 6.4.5.1. Key country dynamics
    • 6.4.5.2. Regulatory framework/ reimbursement structure
    • 6.4.5.3. Competitive scenario
    • 6.4.5.4. Spain market estimates and forecasts 2018 to 2030 (USD Million)
  • 6.4.6. Norway
    • 6.4.6.1. Key country dynamics
    • 6.4.6.2. Regulatory framework/ reimbursement structure
    • 6.4.6.3. Competitive scenario
    • 6.4.6.4. Norway market estimates and forecasts 2018 to 2030 (USD Million)
  • 6.4.7. Sweden
    • 6.4.7.1. Key country dynamics
    • 6.4.7.2. Regulatory framework/ reimbursement structure
    • 6.4.7.3. Competitive scenario
    • 6.4.7.4. Sweden market estimates and forecasts 2018 to 2030 (USD Million)
  • 6.4.8. Denmark
    • 6.4.8.1. Key country dynamics
    • 6.4.8.2. Regulatory framework/ reimbursement structure
    • 6.4.8.3. Competitive scenario
    • 6.4.8.4. Denmark market estimates and forecasts 2018 to 2030 (USD Million)
• 6.5. Asia Pacific
  • 6.5.1. Japan
    • 6.5.1.1. Key country dynamics
    • 6.5.1.2. Regulatory framework/ reimbursement structure
    • 6.5.1.3. Competitive scenario
    • 6.5.1.4. Japan market estimates and forecasts 2018 to 2030 (USD Million)
  • 6.5.2. China
    • 6.5.2.1. Key country dynamics
    • 6.5.2.2. Regulatory framework/ reimbursement structure
    • 6.5.2.3. Competitive scenario
    • 6.5.2.4. China market estimates and forecasts 2018 to 2030 (USD Million)
  • 6.5.3. India
    • 6.5.3.1. Key country dynamics
    • 6.5.3.2. Regulatory framework/ reimbursement structure
    • 6.5.3.3. Competitive scenario
    • 6.5.3.4. India market estimates and forecasts 2018 to 2030 (USD Million)
  • 6.5.4. Australia
    • 6.5.4.1. Key country dynamics
    • 6.5.4.2. Regulatory framework/ reimbursement structure
    • 6.5.4.3. Competitive scenario
    • 6.5.4.4. Australia market estimates and forecasts 2018 to 2030 (USD Million)
  • 6.5.5. South Korea
    • 6.5.5.1. Key country dynamics
    • 6.5.5.2. Regulatory framework/ reimbursement structure
    • 6.5.5.3. Competitive scenario
    • 6.5.5.4. South Korea market estimates and forecasts 2018 to 2030 (USD Million)
  • 6.5.6. Thailand
    • 6.5.6.1. Key country dynamics
    • 6.5.6.2. Regulatory framework/ reimbursement structure
    • 6.5.6.3. Competitive scenario
    • 6.5.6.4. Thailand market estimates and forecasts 2018 to 2030 (USD Million)
• 6.6. Latin America
  • 6.6.1. Brazil
    • 6.6.1.1. Key country dynamics
    • 6.6.1.2. Regulatory framework/ reimbursement structure
    • 6.6.1.3. Competitive scenario
    • 6.6.1.4. Brazil market estimates and forecasts 2018 to 2030 (USD Million)
  • 6.6.2. Argentina
    • 6.6.2.1. Key country dynamics
    • 6.6.2.2. Regulatory framework/ reimbursement structure
    • 6.6.2.3. Competitive scenario
    • 6.6.2.4. Argentina market estimates and forecasts 2018 to 2030 (USD Million)
• 6.7. MEA
  • 6.7.1. South Africa
    • 6.7.1.1. Key country dynamics
    • 6.7.1.2. Regulatory framework/ reimbursement structure
    • 6.7.1.3. Competitive scenario
    • 6.7.1.4. South Africa market estimates and forecasts 2018 to 2030 (USD Million)
  • 6.7.2. Saudi Arabia
    • 6.7.2.1. Key country dynamics
    • 6.7.2.2. Regulatory framework/ reimbursement structure
    • 6.7.2.3. Competitive scenario
    • 6.7.2.4. Saudi Arabia market estimates and forecasts 2018 to 2030 (USD Million)
  • 6.7.3. UAE
    • 6.7.3.1. Key country dynamics
    • 6.7.3.2. Regulatory framework/ reimbursement structure
    • 6.7.3.3. Competitive scenario
    • 6.7.3.4. UAE market estimates and forecasts 2018 to 2030 (USD Million)
  • 6.7.4. Kuwait
    • 6.7.4.1. Key country dynamics
    • 6.7.4.2. Regulatory framework/ reimbursement structure
    • 6.7.4.3. Competitive scenario
    • 6.7.4.4. Kuwait market estimates and forecasts 2018 to 2030 (USD Million)

Chapter 7. Competitive Landscape

• 7.1. Company Categorization
• 7.2. Recent Developments & Impact Analysis by Key Market Participants
• 7.3. Company Market Share Analysis, 2024
• 7.4. Company overview
  • 7.4.1. Regeneron Pharmaceuticals, Inc.
    • 7.4.1.1. Company Overview
    • 7.4.1.2. Financial performance
    • 7.4.1.3. Product benchmarking
    • 7.4.1.4. Strategic initiatives
  • 7.4.2. Bayer AG
    • 7.4.2.1. Company Overview
    • 7.4.2.2. Financial performance
    • 7.4.2.3. Product benchmarking
    • 7.4.2.4. Strategic initiatives
  • 7.4.3. Novartis AG
    • 7.4.3.1. Company Overview
    • 7.4.3.2. Financial performance
    • 7.4.3.3. Product benchmarking
    • 7.4.3.4. Strategic initiatives
  • 7.4.4. F. Hoffmann-La Roche Ltd.
    • 7.4.4.1. Company Overview
    • 7.4.4.2. Financial performance
    • 7.4.4.3. Product benchmarking
    • 7.4.4.4. Strategic initiatives
  • 7.4.5. Biogen
    • 7.4.5.1. Company Overview
    • 7.4.5.2. Financial performance
    • 7.4.5.3. Product benchmarking
    • 7.4.5.4. Strategic initiatives
  • 7.4.6. Pfizer, Inc.
    • 7.4.6.1. Company Overview
    • 7.4.6.2. Financial performance
    • 7.4.6.3. Product benchmarking
    • 7.4.6.4. Strategic initiatives
  • 7.4.7. Coherus BioSciences, Inc.
    • 7.4.7.1. Company Overview
    • 7.4.7.2. Financial performance
    • 7.4.7.3. Product benchmarking
    • 7.4.7.4. Strategic initiatives
  • 7.4.8. Amgen, Inc.
    • 7.4.8.1. Company Overview
    • 7.4.8.2. Financial performance
    • 7.4.8.3. Product benchmarking
    • 7.4.8.4. Strategic initiatives
  • 7.4.9. Bausch Health Companies, Inc.
    • 7.4.9.1. Company Overview
    • 7.4.9.2. Financial performance
    • 7.4.9.3. Product benchmarking
    • 7.4.9.4. Strategic initiatives
  • 7.4.10. Viatris, Inc.
    • 7.4.10.1. Company Overview
    • 7.4.10.2. Financial performance
    • 7.4.10.3. Product benchmarking
    • 7.4.10.4. Strategic initiatives

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