한글목차

약제 요약

JARDIANCE(일반명: 엠파글리플로진)는 주로 신장에서 포도당 재흡수를 담당하는 운송체인 SGLT2를 억제하는 약물로, 2형 당뇨병 치료제 중 최초로 여러 국가에서 심혈관 질환으로 인한 사망 위험 감소에 대한 자료가 첨부된 바 있습니다. 엠파글리플로진은 신장에서 포도당의 재흡수를 억제하고 소변으로 포도당 배설량을 증가시켜 혈당을 낮춥니다. 작용 시간이 비교적 길어 하루 한 번만 복용하면 됩니다. 작용기전이 포도당의 신장 배설에 의존하기 때문에 급성 신장애가 있는 경우 투여를 자제하거나 만성 신장 질환이 있는 경우 투여를 중단할 수 있습니다.

현재 회사는 3상(EMPACT-MI) 연구(EMPACT-MI: EMPAgliflozin for the prevention of chronic heart failure and mortality after an AMI)를 진행 중입니다. 급성 심근경색으로 입원한 성인 환자를 대상으로 JARDIANCE의 유효성과 안전성을 검토하는 다기관 무작위배정, 맹검, 위약대조 시험으로 2023년 데이터를 확보할 예정입니다. 이 임상은 SGLT2 억제제 중 가장 광범위하고 종합적인 EMPOWER 임상 프로그램의 일환으로, JARDIANCE가 심장, 신장, 대사 질환 전반에 걸쳐 환자의 삶에 미치는 영향을 검토할 예정입니다.

주요 7 시장(미국·독일·프랑스·이탈리아·스페인·영국·일본)의 심근경색용 JARDIANCE에 대해 조사분석했으며, 작용기서, 용법과 용량, 연구개발 활동에 관한 인사이트, 매출의 예측 등을 제공하고 있습니다.

목차

제1장 리포트의 서론

제2장 심근경색에서의 JARDIANCE 개요

• 제품의 상세
• 임상 개발
  • 임상 연구
  • 임상시험 정보
  • 안전성과 유효성
• 기타 개발 활동
• 제품 개요

제3장 경쟁 구도(출시 치료법)

제4장 경쟁 구도(후기 신치료법)

제5장 JARDIANCE 시장 평가

• 심근경색에서 JARDIANCE의 시장 전망
• 주요 7 시장 분석
  • 주요 7 시장 심근경색용 JARDIANCE의 시장 규모
• 시장 분석 : 국가별
  • 미국의 심근경색용 JARDIANCE의 시장 규모
  • 독일의 심근경색용 JARDIANCE의 시장 규모
  • 영국의 심근경색용 JARDIANCE의 시장 규모

제6장 SWOT 분석

제7장 애널리스트의 견해

제8장 부록

제9장 DelveInsight의 서비스 내용

제10장 면책사항

제11장 DelveInsight 소개

제12장 리포트 구입 옵션

영문목차

"JARDIANCE Market Size, Forecast, and Emerging Insight - 2032" report provides comprehensive insights about JARDIANCE for myocardial infarction in the seven major markets. A detailed picture of the JARDIANCE for myocardial infarction in the 7MM, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan for the study period 2019 -2032 is provided in this report along with a detailed description of the JARDIANCE for myocardial infarction. The report provides insights about mechanism of action, dosage and administration, as well as research and development including regulatory milestones, along with other developmental activities. Further, it also consists of future market assessments inclusive of the JARDIANCE market forecast analysis for myocardial infarction in the 7MM, SWOT, analysts' views, comprehensive overview of market competitors, and brief about other emerging therapies in myocardial infarction.

Drug Summary:

JARDIANCE (Empagliflozin) is an inhibitor of sodium-glucose co-transporter-2 (SGLT2), the transporters primarily responsible for glucose re-absorption in the kidney. It is marketed under the brand name JARDIANCE and is the first type 2 diabetes medicine to include cardiovascular death risk reduction data on the label in several countries. Empagliflozin lowers blood glucose levels by preventing glucose re-absorption in the kidneys and increasing the amount of glucose excreted in the urine. It has a relatively long duration of action requiring only once-daily dosing. As its mechanism of action is contingent on the renal excretion of glucose, empagliflozin may be held in cases of acute kidney injury and/or discontinued in patients who develop chronic renal disease.

Currently, the company is conducting a Phase III (EMPACT-MI) study. EMPACT-MI (EMPAgliflozin for the prevention of chronic heart failure and mortality after an AMI) is a streamlined, randomized, blinded, placebo-controlled, multicenter trial exploring the efficacy and safety of JARDIANCE in adults hospitalized with an acute MI with data anticipated in 2023. The trial is part of the EMPOWER clinical trial program, the broadest and most comprehensive of any SGLT2 inhibitor, exploring the impact of JARDIANCE on people's lives across the spectrum of cardio-renal-metabolic conditions.

Scope of the Report:

The report provides insights into:

• A comprehensive product overview including the JARDIANCE description, mechanism of action, dosage and administration, research and development activities in myocardial infarction.
• Elaborated details on JARDIANCE regulatory milestones and other development activities have been provided in this report.
• The report also highlights the JARDIANCE research and development activities in myocardial infarction across the United States, Europe and Japan.
• The report also covers the patents information with expiry timeline around JARDIANCE.
• The report contains forecasted sales of JARDIANCE for myocardial infarction till 2032.
• Comprehensive coverage of the late-stage emerging therapies for myocardial infarction.
• The report also features the SWOT analysis with analyst views for JARDIANCE in myocardial infarction.

Methodology:

The report is built using data and information sourced primarily from internal databases, primary and secondary research and in-house analysis by DelveInsight's team of industry experts. Information and data from the secondary sources have been obtained from various printable and nonprintable sources like search engines, news websites, global regulatory authorities websites, trade journals, white papers, magazines, books, trade associations, industry associations, industry portals and access to available databases.

JARDIANCE Analytical Perspective by DelveInsight

• In-depth JARDIANCE Market Assessment

This report provides a detailed market assessment of JARDIANCE for myocardial infarction in the seven major markets, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan. This segment of the report provides forecasted sales data from 2024 to 2032.

• JARDIANCE Clinical Assessment

The report provides the clinical trials information of JARDIANCE for myocardial infarction covering trial interventions, trial conditions, trial status, start and completion dates.

Report Highlights:

• In the coming years, the market scenario for myocardial infarction is set to change due to the extensive research and incremental healthcare spending across the world; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market.
• The companies are developing therapies that focus on novel approaches to treat/improve the disease condition, assess challenges, and seek opportunities that could influence JARDIANCE dominance.
• Other emerging products for myocardial infarction are expected to give tough market competition to JARDIANCE and launch of late-stage emerging therapies in the near future will significantly impact the market.
• A detailed description of regulatory milestones, and developmental activities, provide the current development scenario of JARDIANCE in myocardial infarction.
• Our in-depth analysis of the forecasted sales data of JARDIANCE from 2024 to 2032 will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the JARDIANCE in myocardial infarction.

Key Questions:

• What is the product type, route of administration and mechanism of action of JARDIANCE?
• What is the clinical trial status of the study related to JARDIANCE in myocardial infarction and study completion date?
• What are the key collaborations, mergers and acquisitions, licensing and other activities related to the JARDIANCE development?
• What are the key designations that have been granted to JARDIANCE for myocardial infarction?
• What is the forecasted market scenario of JARDIANCE for myocardial infarction?
• What are the forecasted sales of JARDIANCE in the seven major countries, including the United States, Europe (Germany, France, Italy, Spain, and the United Kingdom), and Japan?
• What are the other emerging products available and how are these giving competition to JARDIANCE for myocardial infarction?
• Which are the late-stage emerging therapies under development for the treatment of myocardial infarction?

Table of Contents

1. Report Introduction

2. JARDIANCE Overview in myocardial infarction

• 2.1. Product Detail
• 2.2. Clinical Development
  • 2.2.1. Clinical studies
  • 2.2.2. Clinical trials information
  • 2.2.3. Safety and efficacy
• 2.3. Other Developmental Activities
• 2.4. Product Profile

3. Competitive Landscape (Marketed Therapies)

4. Competitive Landscape (Late-stage Emerging Therapies)

5. JARDIANCE Market Assessment

• 5.1. Market Outlook of JARDIANCE in myocardial infarction
• 5.2. 7MM Analysis
  • 5.2.1. Market Size of JARDIANCE in the 7MM for myocardial infarction
• 5.3. Country-wise Market Analysis
  • 5.3.1. Market Size of JARDIANCE in the United States for myocardial infarction
  • 5.3.2. Market Size of JARDIANCE in Germany for myocardial infarction
  • 5.3.3. Market Size of JARDIANCE in France for myocardial infarction
  • 5.3.4. Market Size of JARDIANCE in Italy for myocardial infarction
  • 5.3.5. Market Size of JARDIANCE in Spain for myocardial infarction
  • 5.3.6. Market Size of JARDIANCE in the United Kingdom for myocardial infarction
  • 5.3.7. Market Size of JARDIANCE in Japan for myocardial infarction

6. SWOT Analysis

7. Analysts' Views

8. Appendix

• 8.1. Bibliography
• 8.2. Report Methodology

9. DelveInsight Capabilities

10. Disclaimer

11. About DelveInsight

12. Report Purchase Options