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Sarcopenia Market Insight, Epidemiology And Market Forecast - 2032
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ÆäÀÌÁö Á¤º¸ : ¿µ¹® 136 Pages
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Key Highlights:

DelveInsight's "Sarcopenia - Market Insights, Epidemiology, and Market Forecast - 2032" report delivers an in-depth understanding of the Sarcopenia, historical and forecasted epidemiology and the Sarcopenia market trends in the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan.

The Sarcopenia market report provides current treatment practices, emerging drugs, market share of individual therapies, and current and forecasted 7MM Sarcopenia market size from 2019 to 2032. The report also covers current Sarcopenia treatment practices/algorithms and unmet medical needs to curate the best of the opportunities and assesses the underlying potential of the market.

Geography Covered:

Study Period: 2019-2032.

Disease Understanding and Treatment Algorithm

Sarcopenia Overview

Sarcopenia is an age-related condition marked by the progressive loss of skeletal muscle mass, strength, and function. While a decline in muscle mass and quality is a natural part of aging, sarcopenia signifies an accelerated and pathological manifestation of this phenomenon. Factors contributing to its onset include hormonal changes, reduced physical activity, insufficient nutrition, and chronic illnesses. Sarcopenia can result in decreased mobility, heightened susceptibility to falls and fractures, and an overall diminished quality of life.

Sarcopenia Diagnosis

Diagnosing sarcopenia involves a comprehensive assessment that includes clinical evaluation, muscle mass measurement, and functional testing. While there is no single definitive diagnostic criterion, common methods include dual-energy X-ray absorptiometry (DXA), bioelectrical impedance analysis (BIA), and magnetic resonance imaging (MRI) to quantify muscle mass. Additionally, physical performance tests like gait speed, chair stands, and grip strength are often employed to assess functional capacity. The diagnosis considers an individual's age, gender, and overall health, comparing muscle mass and function to established reference values. Integrating these diverse measures provides a holistic understanding of the presence and severity of sarcopenia, guiding appropriate interventions and management strategies.

Sarcopenia Treatment

The treatment of sarcopenia typically involves a multifaceted approach addressing both lifestyle and medical factors. Resistance training exercises, focusing on progressive strength training, are central to improving muscle mass and function. Adequate protein intake, along with balanced nutrition, plays a crucial role in supporting muscle health. Vitamin D and calcium supplementation may be recommended, especially if deficiencies are identified.

In some cases, hormone replacement therapies and medications targeting muscle function and overall health may be considered. A personalized treatment plan, tailored to the individual's specific needs and underlying health conditions, is essential for effectively managing sarcopenia and promoting functional independence in older adults. Regular monitoring and adjustments to the treatment plan are often necessary to optimize outcomes.

Sarcopenia Epidemiology

As the market is derived using the patient-based model, the Sarcopenia epidemiology chapter in the report provides historical as well as forecasted epidemiology segmented by Total Diagnosed Prevalent Cases of Sarcopenia, Gender-specific Diagnosed Prevalent cases of Sarcopenia, Age-specific Diagnosed Prevalent cases of Sarcopenia, and Severity-specific Diagnosed Prevalent cases of Sarcopenia in the 7MM covering the United States, EU4 countries (Germany, France, Italy, and Spain) and the United Kingdom, and Japan, from 2019 to 2032. As per DelveInsight's estimations, the total diagnosed prevalent cases of Sarcopenia in the 7MM was approximately 27 million in 2022 and are projected to increase during the forecast period.

Sarcopenia Drug Chapters

The drug chapter segment of the Sarcopenia report encloses a detailed analysis of Sarcopenia marketed drugs and mid-late stage (Phase III and Phase II) pipeline drugs. It also understands Sarcopenia clinical trial details, expressive pharmacological action, agreements and collaborations, approval, and patent details, advantages and disadvantages of each included drug, and the latest news and press releases.

Emerging Drugs

Sarconeos (BIO101): Biophytis

Biophytis is developing Sarconeos (BIO101), an orally administered small molecule for neuromuscular diseases. Activating the MAS receptor in muscle cells, Sarconeos enhances biological resilience, preserving muscle function in age-related and wasting conditions. The MAS receptor is crucial in the Renin-Angiotensin System, regulating physiological functions. Positive Phase II results demonstrate improved gait speed and safety over 9 months. Anticipated global collaborations aim to advance BIO101 to Phase III, potentially addressing the unmet need in sarcopenia treatment and transforming this therapeutic field.

MYMD-1: MyMD Pharmaceuticals, Inc.

MYMD-1 is a novel therapeutic designed to address aging-related conditions such as sarcopenia and depression, particularly in the context of age or inflammatory-related diseases. Additionally, it demonstrates promise as an antifibrotic and antiprolific treatment. Functioning as a next-generation TNF-alpha inhibitor, MYMD-1 is administered orally, offering a more convenient and safer alternative compared to existing anti-TNF therapies. This innovation holds potential to provide meaningful therapeutic solutions for patients not effectively served by current TNF-alpha inhibitors.

Note: Detailed emerging therapies assessment will be provided in the final report of Sarcopenia.

Sarcopenia Market Outlook

Sarcopenia treatment can be broadly classified into lifestyle interventions, nutritional strategies, and, in some cases, pharmacological approaches. Lifestyle interventions primarily focus on resistance training exercises to improve muscle mass and strength. Nutritional strategies involve ensuring an adequate intake of protein and other essential nutrients crucial for muscle health. Pharmacological approaches may include hormone replacement therapies, such as testosterone or growth hormone, as well as emerging drug candidates targeting muscle function. The classification and selection of treatment modalities depend on the severity of sarcopenia, underlying health conditions, and individual patient characteristics, emphasizing a comprehensive and personalized approach to effectively manage this age-related condition.

The market for Sarcopenia is expected to experience positive growth with the approval of potential drugs like Sarconeos (BIO101) and MYMD-1.

Sarcopenia Drugs Uptake

This section focuses on the uptake rate of potential drugs expected to launch in the market during 2019-2032. For example, Sarconeos (BIO101) in the US is expected to be launched by 2027.

Further detailed analysis of emerging therapies drug uptake in the report…

Sarcopenia Pipeline Development Activities

The report provides insights into different therapeutic candidates in Phase III, Phase II, and Phase I stage. It also analyzes key players involved in developing targeted therapeutics.

Pipeline Development Activities

The report covers information on collaborations, acquisitions and mergers, licensing, and patent details for Sarcopenia emerging therapies.

KOL Views

To keep up with current market trends, we take KOLs and SMEs' opinions working in the domain through primary research to fill the data gaps and validate the secondary research. Industry Experts were contacted for insights on Sarcopenia evolving treatment landscape, patient reliance on conventional therapies, patient therapy switching acceptability, and drug uptake along with challenges related to accessibility, including KOL from University of Maryland School of Medicine, Baltimore, Maryland; Division of General Internal, Medicine and Geriatric Medicine, Albuquerque, New Mexico; Center for Geriatric Medicine, University Heidelberg, Agaplesion Bethanien Krankenhaus, Heidelberg; Department of Epidemiology, University of Oxford; Tokyo Metropolitan Institute of Gerontology, Tokyo, and others.

DelveInsight's analysts connected with 50+ KOLs to gather insights; however, interviews were conducted with 15+ KOLs in the 7MM. Their opinion helps understand and validate current and emerging therapies, treatment patterns, or Sarcopenia market trends. This will support the clients in potential upcoming novel treatments by identifying the overall scenario of the market and the unmet needs.

Qualitative Analysis

We perform Qualitative and market Intelligence analysis using various approaches, such as SWOT and Conjoint Analysis. In the SWOT analysis, strengths, weaknesses, opportunities, and threats in terms of disease diagnosis, patient awareness, patient burden, competitive landscape, cost-effectiveness, and geographical accessibility of therapies are provided. These pointers are based on the Analyst's discretion and assessment of the patient burden, cost analysis, and existing and evolving treatment landscape.

Conjoint Analysis analyzes multiple approved and emerging therapies based on relevant attributes such as safety, efficacy, frequency of administration, route of administration, and order of entry. Scoring is given based on these parameters to analyze the effectiveness of therapy.

Further, the therapies' safety is evaluated wherein the acceptability, tolerability, and adverse events are majorly observed, and it sets a clear understanding of the side effects posed by the drug in the trials. In addition, the scoring is also based on the route of administration, order of entry and designation, probability of success, and the addressable patient pool for each therapy. According to these parameters, the final weightage score and the ranking of the emerging therapies are decided.

Market Access and Reimbursement

The high cost of therapies for the treatment is a major factor restraining the growth of the global drug market. Because of the high cost, the economic burden is increasing, leading the patient to escape from proper treatment.

The report further provides detailed insights on the country-wise accessibility and reimbursement scenarios, cost-effectiveness scenario of approved therapies, programs making accessibility easier and out-of-pocket costs more affordable, insights on patients insured under federal or state government prescription drug programs, etc.

Scope of the Report:

Sarcopenia Report Insights

Sarcopenia Report Key Strengths

Sarcopenia Report Assessment

Key Questions:

Market Insights

Epidemiology Insights

Current Treatment Scenario, Marketed Drugs, and Emerging Therapies

Reasons to Buy:

Frequently Asked Questions

1. What is the forecast period covered in the report?

2. What are the challenges faced by the sarcopenia treatment market?

3. Who are the key players in the Sarcopenia market?

4. How is the market size estimated in the forecast report?

5. What is the key driver of the Sarcopenia market? What is the expected impact of emerging therapies or advancements in Sarcopenia treatment on the market?

6. Does the report provide insights into the competitive landscape of the market?

Table of Contents

1. Key Insights

2. Report Introduction

3. Sarcopenia Market Overview at a Glance

4. Epidemiology and Market Methodology of Sarcopenia

5. Executive Summary of Sarcopenia

6. Key Events

7. Disease Background and Overview of Sarcopenia

8. Epidemiology and Patient Population

9. Patient Journey of Sarcopenia

10. Emerging Therapies

11. Sarcopenia: Market Analysis

12. Key Opinion Leaders' Views

13. SWOT Analysis

14. Unmet Needs

15. Market Access and Reimbursement

16. Appendix

17. DelveInsight Capabilities

18. Disclaimer

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