한글목차

주요 7 시장(미국, 독일, 프랑스, 이탈리아, 스페인, 영국, 일본)에서 킴리아(KYMRIAH)에 대해 조사분석했으며, 작용기서, 용법과 용량, 연구개발 활동에 관한 인사이트 및 시장 예측 등을 제공하고 있습니다.

목차

제1장 리포트의 서론

제2장 DLBCL용 킴리아의 개요

• 제품 상세
• 임상 개발
  • 임상 연구
  • 임상시험 정보
  • 안전성과 유효성
• 규제상 마일스톤
• 기타 개발 활동
• 제품 개요

제3장 경쟁 구도(출시 치료법)

제4장 경쟁 구도(후기 신치료법)

제5장 킴리아 시장 평가

• DLBCL용 킴리아의 시장 전망
• 주요 7 시장 분석
  • 주요 7 시장의 DLBCL용 킴리아의 시장 규모
• 시장 분석 : 국가별
  • 미국의 DLBCL용 킴리아의 시장 규모
  • 독일의 DLBCL용 킴리아의 시장 규모
  • 영국의 DLBCL용 킴리아의 시장 규모

제6장 SWOT 분석

제7장 애널리스트의 견해

제8장 부록

제9장 DelveInsight의 서비스 내용

제10장 면책사항

제11장 DelveInsight 소개

제12장 리포트 구입 옵션

영문목차

"KYMRIAH Drug Insight and Market Forecast - 2032" report provides comprehensive insights about KYMRIAH for Diffuse Large B-cell lymphoma (DLBCL) in the seven major markets. A detailed picture of the KYMRIAH for DLBCL in the 7MM, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan for the study period 2019 -2032 is provided in this report along with a detailed description of the KYMRIAH for DLBCL. The report provides insights about mechanism of action, dosage and administration, as well as research and development including regulatory milestones, along with other developmental activities. Further, it also consists of future market assessments inclusive of the KYMRIAH market forecast analysis for DLBCL in the 7MM, SWOT, analysts' views, comprehensive overview of market competitors, and brief about other emerging therapies in DLBCL.

Drug Summary:

KYMRIAH (tisagenlecleucel) is a CD19-directed genetically modified autologous T-cell immunotherapy comprised of autologous T cells that are genetically modified using a lentiviral vector to encode an anti-CD19 chimeric antigen receptor (CAR). The CAR comprises a murine single-chain antibody fragment (scFv) specific for CD19, followed by a CD8 hinge and transmembrane region fused to the intracellular signaling domains for 4-1BB (CD137) and CD3 zeta.

It involves reprogramming a patient's T cells with a transgene encoding a chimeric antigen receptor (CAR) to identify and eliminate CD19-expressing malignant and normal cells. The CAR comprises a murine single-chain antibody fragment that recognizes CD19 and is fused to intracellular signaling domains from 4-1BB (CD137) and CD3 zeta. The CD3 zeta component is critical for initiating T-cell activation and antitumor activity, upon binding to CD19-expressing cells, the CAR transmits a signal to promote T-cell expansion, activation, target cell elimination, and persistence of the KYMRIAH cells.

KYMRIAH is approved for treating adult patients with R/R large B-cell lymphoma after two or more lines of systemic therapy, including DLBCL not otherwise specified, primary mediastinal large B-cell, high-grade B-cell lymphoma, and DLBCL arising from follicular lymphoma.

Scope of the Report:

The report provides insights into:

• A comprehensive product overview including the KYMRIAH description, mechanism of action, dosage and administration, research and development activities in Diffuse Large B-cell lymphoma (DLBCL).
• Elaborated details on KYMRIAH regulatory milestones and other development activities have been provided in this report.
• The report also highlights the KYMRIAH research and development activities in DLBCL across the United States, Europe and Japan.
• The report also covers the patents information with expiry timeline around KYMRIAH.
• The report contains forecasted sales of KYMRIAH for DLBCL till 2032.
• Comprehensive coverage of the late-stage emerging therapies for DLBCL.
• The report also features the SWOT analysis with analyst views for KYMRIAH in DLBCL.

Methodology:

The report is built using data and information sourced primarily from internal databases, primary and secondary research and in-house analysis by DelveInsight's team of industry experts. Information and data from the secondary sources have been obtained from various printable and nonprintable sources like search engines, news websites, global regulatory authorities websites, trade journals, white papers, magazines, books, trade associations, industry associations, industry portals and access to available databases.

KYMRIAH Analytical Perspective by DelveInsight

In-depth KYMRIAH Market Assessment

This report provides a detailed market assessment of KYMRIAH for Diffuse Large B-cell lymphoma (DLBCL) in the seven major markets, i.e., the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan. This segment of the report provides forecasted sales data from 2023 to 2032.

KYMRIAH Clinical Assessment

The report provides the clinical trials information of KYMRIAH for DLBCL covering trial interventions, trial conditions, trial status, start and completion dates.

Report Highlights:

• In the coming years, the market scenario for Diffuse Large B-cell lymphoma (DLBCL) is set to change due to the extensive research and incremental healthcare spending across the world; which would expand the size of the market to enable the drug manufacturers to penetrate more into the market.
• The companies are developing therapies that focus on novel approaches to treat/improve the disease condition, assess challenges, and seek opportunities that could influence KYMRIAH dominance.
• Other emerging products for DLBCL are expected to give tough market competition to KYMRIAH and launch of late-stage emerging therapies in the near future will significantly impact the market.
• A detailed description of regulatory milestones, and developmental activities, provide the current development scenario of KYMRIAH in DLBCL.
• Our in-depth analysis of the forecasted sales data of KYMRIAH from 2023 to 2032 will support the clients in the decision-making process regarding their therapeutic portfolio by identifying the overall scenario of the KYMRIAH in DLBCL.

Key Questions:

• What is the product type, route of administration and mechanism of action of KYMRIAH?
• What is the clinical trial status of the study related to KYMRIAH in Diffuse Large B-cell lymphoma (DLBCL) and study completion date?
• What are the key collaborations, mergers and acquisitions, licensing and other activities related to the KYMRIAH development?
• What are the key designations that have been granted to KYMRIAH for DLBCL?
• What is the forecasted market scenario of KYMRIAH for DLBCL?
• What are the forecasted sales of KYMRIAH in the seven major countries, including the United States, Europe (Germany, France, Italy, Spain, and the United Kingdom), and Japan?
• What are the other emerging products available and how are these giving competition to KYMRIAH for DLBCL?
• Which are the late-stage emerging therapies under development for the treatment of DLBCL?

Table of Contents

1. Report Introduction

2. KYMRIAH Overview in DLBCL

• 2.1. Product Detail
• 2.2. Clinical Development
  • 2.2.1. Clinical studies
  • 2.2.2. Clinical trials information
  • 2.2.3. Safety and efficacy
• 2.3. Regulatory Milestone
• 2.4. Other Developmental Activities
• 2.5. Product Profile

3. Competitive Landscape (Marketed Therapies)

4. Competitive Landscape (Late-stage Emerging Therapies)

5. KYMRIAH Market Assessment

• 5.1. Market Outlook of KYMRIAH in DLBCL
• 5.2. 7MM Analysis
  • 5.2.1. Market Size of KYMRIAH in the 7MM for DLBCL
• 5.3. Country-wise Market Analysis
  • 5.3.1. Market Size of KYMRIAH in the United States for DLBCL
  • 5.3.2. Market Size of KYMRIAH in Germany for DLBCL
  • 5.3.3. Market Size of KYMRIAH in France for DLBCL
  • 5.3.4. Market Size of KYMRIAH in Italy for DLBCL
  • 5.3.5. Market Size of KYMRIAH in Spain for DLBCL
  • 5.3.6. Market Size of KYMRIAH in the United Kingdom for DLBCL
  • 5.3.7. Market Size of KYMRIAH in Japan for DLBCL

6. SWOT Analysis

7. Analysts' Views

8. Appendix

• 8.1. Bibliography
• 8.2. Report Methodology

9. DelveInsight Capabilities

10. Disclaimer

11. About DelveInsight

12. Report Purchase Options