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Thermo Fisher Scientific Inc.
Merck KGaA
Qiagen N.V.
F. Hoffmann-La Roche Ltd.
New England Biolabs
Worthington Biochemical Corporation
Norgen Biotek Corp.
BIORON GmbH
Sisco Research Laboratories Pvt. Ltd
Bioline(Meridian Biosciences Inc.)
Promega Corporation
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Proteinase K Market is estimated to be valued at USD 31.5 Mn in 2025 and is expected to reach USD 48.0 Mn by 2032, growing at a compound annual growth rate (CAGR) of 6.2% from 2025 to 2032.
Report Coverage
Report Details
Base Year:
2024
Market Size in 2025:
USD 31.5 Mn
Historical Data for:
2020 To 2024
Forecast Period:
2025 To 2032
Forecast Period 2025 to 2032 CAGR:
6.20%
2032 Value Projection:
USD 48.0 Mn
Proteinase K (also known as protease K or endopeptidase K) is a broad-spectrum serine protease widely used in molecular biology. Proteinase K can digest native keratin (hair), hence, the name "Proteinase K". It is commonly used because of its broad specificity, which makes it useful to clean nucleic acid complexes and to lyse cells. It has been used for the isolation of mRNA, and high-molecular-weight DNA and to inactivate other enzymatic activities. The enzyme was discovered in 1974 in extracts of the fungus Engyodontium album (formerly Tritirachium album). Proteinase K is commonly used in molecular biology to digest proteins and remove contamination from preparations of nucleic acid. The addition of proteinase K to nucleic acid preparations rapidly inactivates nucleases that might otherwise degrade the DNA or RNA during purification, hence ideal for these applications. Proteinase K is a cation. It is highly suited to this application since the enzyme is active in the presence of chemicals that denature proteins, such as sodium dodecyl sulphate and urea, chelating agents such as EDTA, sulfhydryl reagents, as well as trypsin or chymotrypsin inhibitors. Proteinase K is used for the destruction of proteins in cell lysates (tissue, cell culture cells) and the release of nucleic acids.
Market Dynamics
In order to accelerate and broaden the development program and to further diversify the company's portfolio, the key market players are focusing on the adoption of growth strategies such as applications of the proteinase K enzyme in novel diagnostic kits which is attributed to the growth of the global Proteinase K market. For instance, according to an article published in the Journal Med, on December 25, 2020, Proteinase K has the potential to work as an affordable, fast, and easy alternative to nucleic acid extraction with only a minor loss of sensitivity. Hence, it was used in SalivaDirect, an alternative diagnostic procedure for COVID-19 that uses saliva instead of nasopharyngeal swabs.
Key features of the study
This report provides an in-depth analysis of the global Proteinase K market and provides market size (US$ Million) and compound annual growth rate (CAGR) for the forecast period 2025-2032, considering 2024 as the base year
It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market
This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends, regional outlook, and competitive strategies adopted by key players
It profiles key players in the global Proteinase K market based on the following parameters-Company highlights, products portfolio, key highlights, financial performance, and strategies
Key companies covered as a part of this study include Thermo Fisher Scientific Inc., Merck KGaA, Qiagen N.V., F. Hoffmann-La Roche Ltd, New England Biolabs. Worthington Biochemical Corporation, Norgen Biotek Corp., Bioron GmbH, Sisco Research Laboratories Pvt. Ltd., Bioline (Meridian Biosciences Inc.), Promega Corporation.
Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future product launches, type up-gradation, market expansion, and marketing tactics
Global Proteinase K Market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts
Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the global proteinase K market
Market Segmentation
Global Proteinase K Market, By Form
Lyophilized Powder Form
Liquid Form
Global Proteinase K Market, By Application
Purificaion of DNA & RNA
In situ Hybridization
Mitochondria Isolation
Enzyme Removal
Global Proteinase K Market, By End User
Contract Research Organization
Academic Institutes
Biotechnology Companies
Diagnosis Laboratories
Global Proteinase K Market, By Region
North America
U.S.
Canada
Latin America
Brazil
Mexico
Argentina
Rest of Latin America
Europe
Germany
U.K.
France
Italy
Spain
Russia
Rest of Europe
Asia Pacific
China
India
Japan
Australia
South Korea
ASEAN
Rest of Asia Pacific
Middle East
GCC
Israel
Rest of Middle East
Africa
South Africa
Central Africa
North Africa
Company Profiles
Thermo Fisher Scientific Inc.
Merck KGaA
Qiagen N.V.
F. Hoffmann-La Roche Ltd.
New England Biolabs
Worthington Biochemical Corporation
Norgen Biotek Corp.
BIORON GmbH
Sisco Research Laboratories Pvt. Ltd.
Bioline (Meridian Biosciences Inc.)
Promega Corporation
Table of Contents
1. Research Objectives and Assumptions
Research Objectives
Assumptions
Abbreviations
2. Market Purview
Report Description
Market Definition and Scope
Executive Summary
Market Snapshot, By Form
Market Snapshot, By Application
Market Snapshot, By End User
Market Snapshot, By Region
Coherent Opportunity Map (COM)
3. Market Dynamics, Regulations, and Trends Analysis
Market Dynamics
Drivers
Restraints
Market Opportunities
Impact Analysis
Recent Product Launches
Epidemiology
Merger, Acquisition, and Collaborations
Regulatory Scenario
Key Developments
PEST Analysis
4. Global Proteinase K Market , By Form, 2020 - 2032, (US$ Million)
Introduction
Market Share Analysis, 2025 and 2032 (%)
Y-o-Y Growth Analysis, 2021-2032
Segment Trends
Lyophilized Powder Form
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020 - 2032, (US$ Mn)
Liquid Form
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020 - 2032, (US$ Mn)
5. Global Proteinase K Market , By Application, 2020 - 2032, (US$ Million)
Introduction
Market Share Analysis, 2025 and 2032 (%)
Y-o-Y Growth Analysis, 2021-2032
Segment Trends
Purification of DNA & RNA
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020 - 2032, (US$ Mn)
In situ Hybridization
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020 - 2032, (US$ Mn)
Mitochondria Isolation
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020 - 2032, (US$ Mn)
Enzyme Removal
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020 - 2032, (US$ Mn)
6. Global Proteinase K Market , By End User , 2020 - 2032, (US$ Million)
Introduction
Market Share Analysis, 2025 and 2032 (%)
Y-o-Y Growth Analysis, 2021-2032
Segment Trends
Contract Research Organization
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020 - 2032, (US$ Mn)
Academic Institutes
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020 - 2032, (US$ Mn)
Biotechnology Companies
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020 - 2032, (US$ Mn)
Diagnostics Laboratories
Introduction
Market Size and Forecast, and Y-o-Y Growth, 2020 - 2032, (US$ Mn)
7. Global Proteinase K Market , By Region, 2020 - 2032, (US$ Million)
Introduction
Market Share Analysis, By Region, 2025 and 2032 (%)
Y-o-Y Growth Analysis, For Regions, 2021-2032
Regional Trends
North America
Introduction
Market Size and Forecast, and Y-o-Y Growth, By Form, 2020 - 2032, (US$ Million)
Market Size and Forecast, and Y-o-Y Growth, By Application , 2020 - 2032, (US$ Million)
Market Size and Forecast, and Y-o-Y Growth, By End user , 2020 - 2032, (US$ Million)
Market Size and Forecast, and Y-o-Y Growth, By Country, 2020 - 2032, (US$ Million)
U.S.
Canada
Latin America
Introduction
Market Size and Forecast, and Y-o-Y Growth, By Form, 2020 - 2032, (US$ Million)
Market Size and Forecast, and Y-o-Y Growth, By Application , 2020 - 2032, (US$ Million)
Market Size and Forecast, and Y-o-Y Growth, By End user , 2020 - 2032, (US$ Million)
Market Size and Forecast, and Y-o-Y Growth, By Country, 2020- 2032, (US$ Million)
Brazil
Mexico
Argentina
Rest of Latin America
Europe
Introduction
Market Size and Forecast, and Y-o-Y Growth, By Form, 2020 - 2032, (US$ Million)
Market Size and Forecast, and Y-o-Y Growth, By Application , 2020 - 2032, (US$ Million)
Market Size and Forecast, and Y-o-Y Growth, By End user , 2020 - 2032, (US$ Million)
Market Size and Forecast, and Y-o-Y Growth, By Country, 2020- 2032, (US$ Million)
U.K.
Germany
Italy
France
Spain
Russia
Rest of Europe
Asia Pacific
Introduction
Market Size and Forecast, and Y-o-Y Growth, By Form, 2020 - 2032, (US$ Million)
Market Size and Forecast, and Y-o-Y Growth, By Application , 2020 - 2032, (US$ Million)
Market Size and Forecast, and Y-o-Y Growth, By End user , 2020 - 2032, (US$ Million)
Market Size and Forecast, and Y-o-Y Growth, By Country, 2020- 2032, (US$ Million)
China
India
Japan
ASEAN
Australia
South Korea
Rest of Asia Pacific
Middle East
Introduction
Market Size and Forecast, and Y-o-Y Growth, By Form, 2020 - 2032, (US$ Million)
Market Size and Forecast, and Y-o-Y Growth, By Application , 2020 - 2032, (US$ Million)
Market Size and Forecast, and Y-o-Y Growth, By End user , 2020 - 2032, (US$ Million)
Market Size and Forecast, and Y-o-Y Growth, By Country, 2020- 2032, (US$ Million)
GCC
Israel
Rest of Middle East
Africa
Introduction
Market Size and Forecast, and Y-o-Y Growth, By Form, 2020 - 2032, (US$ Million)
Market Size and Forecast, and Y-o-Y Growth, By Application , 2020 - 2032, (US$ Million)
Market Size and Forecast, and Y-o-Y Growth, By End user , 2020 - 2032, (US$ Million)
Market Size and Forecast, and Y-o-Y Growth, By Country/Region, 2020- 2032, (US$ Million)